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12 p, 1.1 MB |
Extremely low viral reservoir in treated chronically HIV-1-infected individuals
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Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Jiménez Valero, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Monceaux, Valérie (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Huot, Nicolas (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Leal, Lorna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
González Soler, Victoria (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
González-Cao, María (Hospital Universitari Dexeus (Barcelona, Catalunya)) ;
Müller-Trutwin, Michaela (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Sáez-Cirión, Asier (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
García, Felipe (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
Small viral reservoirs are found predominantly in HIV-1 controllers and individuals treated during acute/early HIV-1 infection. However, other HIV + individuals could naturally also harbour low viral reservoirs. [...]
2020 -  10.1016/j.ebiom.2020.102830
EBioMedicine, Vol. 57 (june 2020)
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9 p, 1.7 MB |
Switching From a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen : A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human Immunodeficiency Virus-infected Individuals
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Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Navarro, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jimenez, Montse (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rutsaert, Sofie (Universitair Ziekenhuis Gent) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron) ;
De Clercq, Laura (Universitair Ziekenhuis Gent) ;
Ribas, Bibiana Planas (Hospital Universitari Vall d'Hebron) ;
Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Vandekerckhove, Linos (Universitair Ziekenhuis Gent) ;
Blanco, Julià (Universitat de Vic - Universitat Central de Catalunya) ;
Crespo Casal, Manuel (Instituto de Investigación Sanitaria Galicia Sur) ;
Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats) ;
Universitat Autònoma de Barcelona
Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted protease inhibitor (PI/r)-based therapy to dolutegravir (DTG)-based therapy. [...]
2018 - 10.1093/cid/ciy1095
Clinical Infectious Diseases, Vol. 69 (december 2018) , p. 1320-1328
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10 p, 2.1 MB |
Sensitive quantification of the HIV-1 reservoir in gut-associated lymphoid tissue
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Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Navarro, Jordi (Hospital Universitari Vall d'Hebron) ;
Carrasco-Rozas, Ana (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Esteve, Maria (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Manyè, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Crespo Casal, Manuel (Hospital Universitari Vall d'Hebron) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martinez Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
Background. The implementation of successful strategies to achieve an HIV cure has become a priority in HIV research. However, the current location and size of HIV reservoirs is still unknown since there are limited tools to evaluate HIV latency in viral sanctuaries such as gut-associated lymphoid tissue (GALT). [...]
2017 - 10.1371/journal.pone.0175899
PloS one, Vol. 12 Núm. 4 (2017) , p. 1-10
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16.
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11 p, 1018.7 KB |
Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects
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Hancock, Gemma ;
Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Kopycinski, Jakub ;
Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Giannoulatou, Eleni (University of New South Wales) ;
Rose, Annie ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Hayton, Emma-Jo ;
Crook, Alison ;
Morgan, Catharine ;
Angus, Brian ;
Chen, Fabian ;
Yang, Hongbing ;
Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Hanke, Tomáš ;
Dorrell, Lucy ;
Universitat Autònoma de Barcelona
Introduction : Vaccines may be key components of a curative strategy for HIV-1. We investigated whether a novel immunogen, HIVconsv, designed to re-direct T cell responses to conserved viral epitopes, could impact the HIV-1 reservoir in chronic antiretroviral therapy (ART)-treated subjects when delivered by modified vaccinia virus Ankara (MVA). [...]
2017 - 10.7448/IAS.20.1.21171
Journal of the International AIDS Society, Vol. 20 (may 2017)
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85 p, 2.1 MB |
Young children (0-8) and digital technology. : A qualitative exploratory study. National report : Spain
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Matsumoto, Mitsuko (Universidad Autónoma de Madrid. Departamento de Psicología Evolutiva y de la Salud) ;
Aliagas, Cristina (Universitat Autònoma de Barcelona. Departament de Didàctica de la Llengua i la Literatura i de les Ciències Socials) ;
Morgade Salgado, Marta (Universidad Autónoma de Madrid. Departamento de Psicología Evolutiva y de la Salud) ;
Correro Iglesias, Cristina 1974- (Universitat Autònoma de Barcelona. Departament de Didàctica de la Llengua i la Literatura i de les Ciències Socials) ;
Galera Suárez, Nieves (Universidad Autónoma de Madrid. Departamento de Psicología Evolutiva y de la Salud) ;
Roncero, Cristina (Universidad Autónoma de Madrid. Departamento de Psicología Evolutiva y de la Salud) ;
Poveda, David (Universidad Autónoma de Madrid. Departamento de Psicología Evolutiva y de la Salud)
The study is a part of a larger qualitative study carried out across 16 European countries aimed at exploring experiences with digital technologies, e. g. smart phones, tablets, computers, TVs, video-games, etc. [...]
2016
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25 p, 1.9 MB |
Discrimination of soils and assessment of soil fertility using information from an ion selective electrodes array and artificial neural networks
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Mimendia Sancho, Aitor (Universitat Autònoma de Barcelona. Departament de Química) ;
Gutiérrez Salgado, Juan Manuel (Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional. Departamento de Ingeniería Eléctrica) ;
Alcañiz, Josep M. (Josep Maria) (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ;
Valle Zafra, Manuel del (Universitat Autònoma de Barcelona. Departament de Química)
Multichannel sensor measurements combined with advanced treatment is the departure point for a new concept in sensorics, the electronic tongue. Our setup worked with an array of 20 ion selective electrodes plus an artificial neural network used as a pattern recognition method applied to soil analysis. [...]
2014 - 10.1002/clen.201300923
CLEAN, Vol. 42, Issue 12 (Dec. 2014) , p. 1808-1815
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4 p, 43.2 KB |
O corpo humano e o discurso expositivo em museus universitários de ciências
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Gruzman, C. (Universidade de São Paulo. Ensino de Ciências e Matemática) ;
Iszlaji, C. (Universidade de São Paulo) ;
Salgado, M. (Universidade de São Paulo. Programa Interunidades em Ensino de Ciências) ;
Senac, A. (Universidade de São Paulo)
Os atuais desafios colocados aos museus e centros de ciências visam aproximar a produção do conhecimento científico e a população. Neste contexto, a concepção e o desenvolvimento das exposições científicas e, mais especificamente, os processos de transformação do conhecimento científico para fins educacionais e de divulgação científica necessitam de debate. [...]
2009
Enseñanza de las ciencias, Núm. Extra (2009) , p. 2420-2423
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