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12 p, 983.1 KB |
Bioavailability of once-daily tacrolimus formulations used in clinical practice in the management of De Novo kidney transplant recipients : the better study
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Fernandez Rivera, Constantino (Complejo Hospitalario Universitario de A Coruña) ;
Calvo Rodríguez, María (Complejo Hospitalario Universitario de A Coruña) ;
Poveda, José Luís (Hospital Universitari i Politècnic La Fe (València)) ;
Pascual, Julio (Pascual Santos) (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Crespo, Marta (Hospital del Mar (Barcelona, Catalunya)) ;
Gomez, Gonzalo (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Cabello Pelegrin, Sheila (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Paul, Javier (Hospital Universitario Miguel Servet (Saragossa)) ;
Lauzurica, Ricardo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perez Mir, Mònica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Moreso, Francesc (Hospital Universitari Vall d'Hebron) ;
Perelló, Manel (Hospital Universitari Vall d'Hebron) ;
Andres, Amado (Hospital 12 de Octubre (Madrid)) ;
González, Esther (Hospital 12 de Octubre (Madrid)) ;
Fernandez, Ana (Hospital Universitario Ramón y Cajal (Madrid)) ;
Mendiluce, Alicia (Hospital Universitario Clínico de Valladolid) ;
Fernández Carbajo, Beatriz (Hospital Universitario Clínico de Valladolid) ;
Sanchez Fructuoso, Ana (Hospital Universitario Clínico San Carlos (Madrid)) ;
Calvo, Natividad (Hospital Universitario Clínico San Carlos (Madrid)) ;
Suarez, Alejandro (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Bernal Blanco, Gabriel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Osuna, Antonio (Hospital Universitario Virgen de las Nieves (Granada)) ;
Ruiz-Fuentes, M. Carmen (Hospital Universitario Virgen de las Nieves (Granada)) ;
Melilli, Edoardo (Hospital Universitari de Bellvitge) ;
Montero, Nuria (Hospital Universitari de Bellvitge) ;
Ramos, Ana (Hospital Universitario Fundación Jiménez Díaz) ;
Fernández, Beatriz (Hospital Universitario Fundación Jiménez Díaz) ;
López, Verónica (Universidad de Málaga) ;
Hernandez, Domingo (Universidad de Málaga) ;
Universitat Autònoma de Barcelona
Multicenter, prospective, observational study to compare the relative bioavailability of once-daily tacrolimus formulations in de novo kidney transplant recipients. De novo kidney transplant recipients who started a tacrolimus-based regimen were included 14 days post-transplant and followed up for 6 months. [...]
2021 -  10.1111/ctr.14550
Clinical Transplantation, Vol. 36 (december 2021)
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12 p, 550.3 KB |
Critically ill patients with community-onset intraabdominal infections : Influence of healthcare exposure on resistance rates and mortality
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Maseda, Emilio (Universidad Autónoma de Madrid) ;
Ramírez, Sofía (Universidad Autónoma de Madrid) ;
Picatto, Pedro (Hospital Universitario Central de Asturias) ;
Peláez-Peláez, Eva (Hospital Universitari Vall d'Hebron) ;
García-Bernedo, Carlos A. (Hospital del Mar (Barcelona, Catalunya)) ;
Ojeda-Betancur, Nazario (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Aguilar, Gerardo (Hospital Clínic Universitari (València)) ;
Forés, Beatriz (Hospital de Basurto (Bilbao, Biscaia)) ;
Solera-Marín, Jorge (Hospital Universitario de Canarias (La Laguna)) ;
Aliaño-Piña, María (Hospital Virgen de la Salud (Toledo)) ;
Tamayo, Eduardo (Hospital Clínico Universitario de Valladolid) ;
Ramasco, Fernando (Hospital Universitario de la Princesa (Madrid)) ;
García-Álvarez, Raquel (Hospital Universitario 12 de Octubre (Madrid)) ;
González-Lisorge, Ada (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Giménez, María-José (Universidad Europea de Madrid) ;
Suárez-de-la-Rica, Alejandro (Universidad Autónoma de Madrid) ;
Universitat Autònoma de Barcelona
The concept of healthcare-associated infections (as opposed to hospital-acquired infections) in intraabdominal infections (IAIs) is scarcely supported by data in the literature. The aim of the present study was to analyse community-onset IAIs (non-postoperative/non-nosocomial) in patients admitted to intensive care units (ICUs), to investigate differences in resistance patterns linked to healthcare exposure and mortality-associated factors. [...]
2019 - 10.1371/journal.pone.0223092
PloS one, Vol. 14 (september 2019)
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18 p, 7.7 MB |
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
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Moreira-Teixeira, Lúcia (The Francis Crick Institute, London) ;
Stimpson, Philippa J. (The Francis Crick Institute, London) ;
Stavropoulos, Evangelos (The Francis Crick Institute, London) ;
Hadebe, Sabelo (The Francis Crick Institute, London) ;
Chakravarty, Probir (The Francis Crick Institute, London) ;
Ioannou, Marianna (The Francis Crick Institute, London) ;
Aramburu, Iker Valle (The Francis Crick Institute, London) ;
Herbert, Eleanor (The Francis Crick Institute, London) ;
Priestnall, Simon L. (The Francis Crick Institute, London) ;
Suarez-Bonnet, Alejandro (The Francis Crick Institute, London) ;
Sousa, Jeremy (Universidade do Porto. ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Porto) ;
Fonseca, Kaori L. (Instituto Gulbenkian de Ciência (IGC), Oeiras) ;
Wang, Qian (The Francis Crick Institute, London) ;
Vashakidze, Sergo (National Center for Tuberculosis and Lung Diseases (NCTLD), Tbilisi) ;
Rodríguez-Martínez, Paula (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vilaplana, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Saraiva, Margarida (Universidade do Porto. IBMC - Instituto de Biologia Molecular e Celular) ;
Papayannopoulos, Venizelos (The Francis Crick Institute, London) ;
O'Garra, Anne (Imperial College London)
Tuberculosis (TB) is a leading cause of mortality due to infectious disease, but the factors determining disease progression are unclear. Transcriptional signatures associated with type I IFN signalling and neutrophilic inflammation were shown to correlate with disease severity in mouse models of TB. [...]
2020 - 10.1038/s41467-020-19412-6
Nature communications, Vol. 11 (november 2020)
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9 p, 1.2 MB |
Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients
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Maseda, Emilio (Madrid, Spain) ;
Grau, Santiago (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Luque, Sonia (Hospital del Mar (Barcelona, Catalunya)) ;
Castillo-Mafla, Maria-Pilar (Paseo de la Castellana 261, 28046 Madrid, Spain) ;
Suárez-de-la-Rica, Alejandro (Paseo de la Castellana 261, 28046 Madrid, Spain) ;
Montero-Feijoo, Ana (Paseo de la Castellana 261, 28046 Madrid, Spain) ;
Salgado, Patricia (Paseo de la Castellana 261, 28046 Madrid, Spain) ;
Gimenez, Maria-Jose (PRISM-AG, Madrid, Spain) ;
García-Bernedo, Carlos A. (Hospital del Mar (Barcelona, Catalunya)) ;
Gilsanz, Fernando (Madrid, Spain) ;
Roberts, Jason A. (Brisbane, Australia) ;
Universitat Autònoma de Barcelona
Dosing in obese critically ill patients is challenging due to pathophysiological changes derived from obesity and/or critical illness, and it remains fully unexplored. This study estimated the micafungin probability of reaching adequate 24-h area under the curve (AUC)/minimum inhibitory concentration (MIC) values against Candida spp. [...]
2018 - 10.1186/s13054-018-2019-8
Critical Care, Vol. 22 (april 2018)
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31 p, 2.0 MB |
Flexible Graphene Solution-Gated Field-Effect Transistors : Efficient Transducers for Micro-Electrocorticography
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Hébert, Clément (Institut Català de Nanociència i Nanotecnologia) ;
Masvidal Codina, Eduard (Institut Català de Nanociència i Nanotecnologia) ;
Suarez-Pérez, Alejandro (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bonaccini Calia, Andrea (Institut Català de Nanociència i Nanotecnologia) ;
Piret, Gaelle (INSERM U1205 (Grenoble, França)) ;
Garcia Cortadella, Ramon (Institut Català de Nanociència i Nanotecnologia) ;
Illa, Xavi (Institut de Microelectrònica de Barcelona) ;
Del Corro, Elena (Institut Català de Nanociència i Nanotecnologia) ;
De la Cruz, Jose (Institut Català de Nanociència i Nanotecnologia) ;
Viana Casals, Damià (Institut Català de Nanociència i Nanotecnologia) ;
Prats Alfonso, Elisabet (Institut de Microelectrònica de Barcelona) ;
Bousquet, Jessica (Institut Català de Nanociència i Nanotecnologia) ;
Godignon, Philippe (Institut de Microelectrònica de Barcelona) ;
Yvert, Blayse (INSERM U1205 (Grenoble, França)) ;
Villa, Rosa (Institut de Microelectrònica de Barcelona) ;
Sánchez-Vives, María V (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Guimerà Brunet, Anton (Institut de Microelectrònica de Barcelona) ;
Garrido, Jose (Institut Català de Nanociència i Nanotecnologia)
Brain-computer interfaces and neural prostheses based on the detection of electrocorticography (ECoG) signals are rapidly growing fields of research. Several technologies are currently competing to be the first to reach the market; however, none of them fulfill yet all the requirements of the ideal interface with neurons. [...]
2018 - 10.1002/adfm.201703976
Advanced functional materials, Vol. 28, Núm. 12 (March 2018) , article 1703976
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