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1.
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18 p, 1.1 MB |
Motor Fluctuations Development Is Associated with Non-Mostor Symptoms Burden Progression in Parkinson's Disease Patients : A 2-Year Follow-Up Study
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Santos-García, D. (Complejo Hospitalario Universitario de A Coruña (CHUAC)) ;
Deus Fonticoba, T.D. (Complejo Hospitalario Universitario de Ferrol) ;
Bartolomé, C.C. (Complejo Hospitalario Universitario de A Coruña (CHUAC)) ;
Feal Painceiras, M.J. (Complejo Hospitalario Universitario de A Coruña (CHUAC)) ;
Castro, E.S. (Complejo Hospitalario Universitario de Ferrol) ;
Canfield, H. (Complejo Hospitalario Universitario de Ferrol) ;
Miró, C.M. (Complejo Hospitalario Universitario de A Coruña (CHUAC)) ;
Jesús, S. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Aguilar, M. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Pastor, P. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Planellas, Lluis (Hospital Clínic i Provincial de Barcelona) ;
Cosgaya, Marina (Hospital Clínic i Provincial de Barcelona) ;
Caldentey, J.G. ;
Caballol, N. (Hospital de Sant Joan Despí Moisès Broggi) ;
Legarda, I. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Hernández-Vara, Jorge (Hospital Universitari Vall d'Hebron) ;
Cabo, I. (Complejo Hospitalario Universitario de Pontevedra) ;
Manzanares, L.L. (Hospital Universitario de la Princesa (Madrid)) ;
Aramburu, I.G. (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Ávila Rivera, M.A. (Consorci Sanitari Integral. Hospital General de L'Hospitalet) ;
Mayordomo, V.G. (Hospital Universitario Clínico San Carlos (Madrid)) ;
Nogueira, V. (Hospital Da Costa) ;
Puente, Víctor (Hospital del Mar (Barcelona, Catalunya)) ;
García-Soto, J.D. (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Borrué, C. (Hospital Universitario Infanta Sofía (San Sebastián de los Reyes)) ;
Vila, B.S. (Institut Català de la Salut) ;
Sauco, M.Á. (Hospital General Universitario de Elche) ;
Vela, L. (Hospital Universitario Fundación Alcorcón) ;
Escalante, S. (Hospital de Tortosa Verge de la Cinta) ;
Cubo, E. (Complejo Asistencial Universitario de Burgos) ;
Padilla, F.C. (Hospital Universitario de Canarias (La Laguna)) ;
Martínez Castrillo, J.C. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Alonso, P.S. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Alonso Losada, M.G. (Hospital Álvaro Cunqueiro (Vigo)) ;
Ariztegui, N.L. (Complejo Hospitalario de Toledo) ;
Gastón, I. (Complejo Hospitalario de Navarra) ;
Kulisevsky, Jaime (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Blázquez Estrada, M. (Hospital Universitario Central de Asturias) ;
Seijo, M. (Complejo Hospitalario Universitario de Pontevedra) ;
Martínez, J.R. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Valero, C. (Hospital Arnau de Vilanova (València)) ;
Kurtis, M. (Hospital Ruber Internacional) ;
de Fábregues, Oriol (Hospital Universitari Vall d'Hebron) ;
Ardura, J.G. (Hospital Universitario de Cabueñes (Gijón)) ;
Redondo, R.A. (Hospital Universitario Lucus Augusti (Lugo)) ;
Ordás, C. (Hospital Universitario Rey Juan Carlos (Madrid)) ;
López Díaz, L.M. (Complejo Hospitalario Universitario de Ourense) ;
McAfee, D. (University of Maryland School of Medicine) ;
Martinez-Martin, P. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Mir, P. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Santacruz, Pilar (Hospital Clínic i Provincial de Barcelona) ;
Pascual Sedano, Berta María (Institut d'Investigació Biomèdica Sant Pau) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Martí, Maria José (Hospital Clínic i Provincial de Barcelona) ;
Martí-Andres, Gloria (Hospital Universitari Vall d'Hebron) ;
Lucas-del-Pozo, Sara (Hospital Universitari Vall d'Hebron) ;
Horta Barba, Andrea (Institut d'Investigació Biomèdica Sant Pau) ;
Crespo Cuevas, Ane Miren (Hospital del Mar (Barcelona, Catalunya)) ;
Cámara Lorenzo, Ana (Hospital Clínic i Provincial de Barcelona) ;
Bejr-kasem, Helena (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
The aim of the present study was to analyze the progression of non-motor symptoms (NMS) burden in Parkinson's disease (PD) patients regarding the development of motor fluctuations (MF). PD patients without MF at baseline, who were recruited from January 2016 to November 2017 (V0) and evaluated again at a 2-year follow-up (V2) from 35 centers of Spain from the COPPADIS cohort, were included in this analysis. [...]
2022 -  10.3390/diagnostics12051147
Diagnostics, Vol. 12 Núm. 5 (may 2022) , p. 1147
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7 p, 637.7 KB |
Reducing the Frequency of Follow-up Cystoscopy in Low-grade pTa Non-muscle-invasive Bladder Cancer Using the ADXBLADDER Biomarker
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Rouprêt, Morgan (Sorbonne Université GRC 5 Predictive Onco-Uro. Urology Department. AP-HP. Hôpital Pitié-Salpêtrière) ;
Gontero, Paolo (Ospedale Molinette) ;
McCracken, Stuart R.C. (Sunderland Royal Hospital) ;
Dudderidge, Tim (University Hospital Southampton) ;
Stockley, Jacqueline (Arquer Diagnostics) ;
Kennedy, Ashleigh (Arquer Diagnostics) ;
Rodríguez Faba, Óscar (Institut d'Investigació Biomèdica Sant Pau) ;
Sieverink, Caroline (Radboud University Medical Centre) ;
Vanié, Felicien (Hôpital Pitié-Salpêtrière) ;
Allasia, Marco (Ospedale Molinette) ;
Witjes, J.Alfred (Radboud University Medical Centre) ;
Colombel, Marc (Hôpital Edouard Herriot) ;
Longo, Fabrizio (Università Policlinico Milano) ;
Montanari, Emanuele (Università Policlinico Milano) ;
Palou, Joan (Ospedale Molinette) ;
Sylvester, Richard J. (European Association of Urology Non-muscle-invasive Bladder Cancer Guidelines Panel) ;
Universitat Autònoma de Barcelona
Non-muscle-invasive bladder cancer (NMIBC) is one of the most expensive cancers owing to frequent follow-up cystoscopies for detection of recurrence. Objective: To assess if the noninvasive ADXBLADDER urine test could permit a less intensive surveillance schedule for patients with low-grade (LG) pTa tumor without carcinoma in situ (CIS) at the previous diagnosis. [...]
2022 - 10.1016/j.euf.2022.02.006
European Urology Focus, Vol. 8 Núm. 6 (november 2022) , p. 1643-1649
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3.
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11 p, 1.9 MB |
Many people with chronic lymphocytic leukemia or small lymphocytic lymphoma benefit from ibrutinib treatment up to 8 years : a plain language summary
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Barr, Paul M. (University of Rochester Medical Center, USA) ;
Owen, Carolyn (University of Calgary, Canada) ;
Robak, Tadeusz (Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland) ;
Tedeschi, Alessandra (ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy) ;
Bairey, Osnat (Rabin Medical Center, Petah Tikva, Israel) ;
Burger, Jan A (University of Texas MD Anderson Cancer Center, Houston, USA) ;
Hillmen, Peter (The Leeds Teaching Hospitals, St James Institute of Oncology, Leeds, UK) ;
Dearden, Claire (The Royal Marsden Hospital, London, UK) ;
Grosicki, Sebastian (Silesian Medical University, Katowice, Poland) ;
McCarthy, Helen (Royal Bournemouth General Hospital (Dorset, Regne Unit)) ;
Li, Jian Yong (Jiangsu Province Hospital, Nanjing, China) ;
Offner, Fritz (Universitair Ziekenhuis Gent, Belgium) ;
Moreno, Carol (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Jermain, Mandy (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ;
Zhou, Cathy (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ;
Hsu, Emily (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ;
Szoke, Anita (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ;
Kipps, Thomas J. (UCSD Moores Cancer Center, San Diego, USA) ;
Ghia, Paolo (Università Vita-Salute San Raffaele &IRCCS Ospedale San Raffaele, Milan, Italy)
What is this summary about? This is a plain language summary of a publication describing long-term results from the RESONATE-2 study with up to 8 years of follow-up. The original paper was published in Blood Advances in June 2022. [...]
2022 - 10.2217/fon-2022-0898
Future oncology (London, England), Vol. 18 Núm. 37 (january 2022)
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13 p, 680.7 KB |
Macrophages of genetically characterized familial hypercholesterolaemia patients show up-regulation of LDL-receptor-related proteins
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Escate, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Padró, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Borrell-Pages, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Suades, Rosa (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Aledo, Rosa (Institut d'Investigació Biomèdica Sant Pau) ;
Mata, Pedro (Foundation Jimenez Diaz) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Familial hypercholesterolaemia (FH) is a major risk for premature coronary heart disease due to severe long-life exposure to high LDL levels. Accumulation of LDL in the vascular wall triggers atherosclerosis with activation of the innate immunity system. [...]
2017 - 10.1111/jcmm.12993
Journal of Cellular and Molecular Medicine, Vol. 21 Núm. 3 (january 2017) , p. 487-499
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19 p, 837.6 KB |
Malignant bone tumors (other than Ewing's) : clinical practice guidelines for diagnosis, treatment and follow-up by Spanish Group for Research on Sarcomas (GEIS)
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Redondo, Andrés (Hospital Universitario La Paz (Madrid)) ;
Bagué Rosell, Sílvia (Institut d'Investigació Biomèdica Sant Pau) ;
Bernabeu, Daniel (Hospital Universitario La Paz (Madrid)) ;
Ortiz-Cruz, Eduardo (Hospital Universitario La Paz (Madrid)) ;
Valverde, Claudia (Hospital Universitari Vall d'Hebron) ;
Alvarez, Rosa (Hospital General Universitario Gregorio Marañón) ;
Martínez-Trufero, Javier (Hospital Universitario Miguel Servet (Saragossa)) ;
Lopez-Martin, Jose A. (Hospital 12 de Octubre (Madrid)) ;
Correa, Raquel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Cruz, Josefina (Hospital Universitario de Canarias (La Laguna)) ;
López Pousa, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Santos, Aurelio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
García del Muro, Xavier (Institut Catalá d'Oncologia Hospitalet) ;
Martin-Broto, Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Universitat Autònoma de Barcelona
Primary malignant bone tumors are uncommon and heterogeneous malignancies. This document is a guideline developed by the Spanish Group for Research on Sarcoma with the participation of different specialists involved in the diagnosis and treatment of bone sarcomas. [...]
2017 - 10.1007/s00280-017-3436-0
Cancer Chemotherapy and Pharmacology, Vol. 80 Núm. 6 (january 2017) , p. 1113-1131
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41 p, 588.1 KB |
Drivers of plant richness patterns of Mediterranean riparian forests at local and regional scales have bottom-up and top-down effects
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Leo, María (Real Jardín Botánico) ;
Calleja, Juan Antonio (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Lara, Francisco (Universidad Autónoma de Madrid) ;
Garilleti, Ricardo (Universidad de Valencia. Departamento de Botánica y Geología) ;
Medina, Nagore G. (University of South Bohemia. Department of Botany) ;
Universitat Autònoma de Barcelona.
Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia
Questions: It has been long recognized that community species richness depends on factors operating at different spatial scales. Most frequently, across-scale studies have focused on the impact of regional factors on local richness (top-down effects) while few have analyzed the importance of local factors on regional richness (bottom-up) and even fewer have tried to integrate effects on both directions. [...]
2019 - 10.1111/jvs.12728
Journal of vegetation science, Vol. 30, Issue 3 (May 2019) , p. 485-497
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18 p, 1.4 MB |
Intensive follow-up for women with breast cancer : Review of clinical, economic and patient's preference domains through evidence to decision framework
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Lafranconi, Alessandra (European Commission. Joint Research Centre (JRC)) ;
Pylkkänen, Liisa (European Commission. Joint Research Centre (JRC)) ;
Deandrea, Silvia (European Commission. Joint Research Centre (JRC)) ;
Bramesfeld, Anke (European Commission. Joint Research Centre (JRC)) ;
Lerda, Donata (European Commission. Joint Research Centre (JRC)) ;
Neamtiu, Luciana (European Commission. Joint Research Centre (JRC)) ;
Saz-Parkinson, Zuleika (European Commission. Joint Research Centre (JRC)) ;
Posso, Margarita (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Rigau, David (Institut d'Investigació Biomèdica Sant Pau) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Martinez-Zapata, Maria José (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Women treated for breast cancer are followed-up for monitoring of treatment effectiveness and for detecting recurrences at an early stage. The type of follow-up received may affect women's reassurance and impact on their quality of life. [...]
2017 - 10.1186/s12955-017-0779-5
Health and quality of life outcomes, Vol. 15 Núm. 1 (19 2017) , p. 206
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9 p, 500.3 KB |
Extended follow-up and impact of high-risk prognostic factors from the phase 3 RESONATE study in patients with previously treated CLL/SLL
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Brown, J.R. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Hillmen, Peter (St James Institute of Oncology) ;
O'Brien, S. (MD Anderson Cancer Center) ;
Barrientos, J.C. (Hofstra Northwell School of Medicine) ;
Reddy, N.M. (Vanderbilt-Ingram Cancer Center) ;
Coutre, S.E. (Stanford University) ;
Tam, Constantine S (Peter MacCallum Cancer Centre. St Vincent's Hospital) ;
Mulligan, S.P. (Royal North Shore Hospital) ;
Jaeger, U. (Medical University of Vienna) ;
Barr, P.M. (University of Rochester Cancer Center) ;
Furman, R.R. (New York Presbyterian Hospital) ;
Kipps, Thomas J (UCSD Moores Cancer Center) ;
Cymbalista, F. (Hôpital Avicenne) ;
Thornton, P. (Beaumont Hospital (Dublín, Irlanda)) ;
Caligaris-Cappio, F. (Universita Vita-Salute San Raffaele) ;
Delgado, J. (Hospital Clínic i Provincial de Barcelona) ;
Montillo, M. (Niguarda Hospital) ;
DeVos, S. (David Geffen School of Medicine at UCLA) ;
Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ;
Pagel, J.M. (Swedish Cancer Institute) ;
Munir, Talha (St James Institute of Oncology) ;
Burger, Jan A (MD Anderson Cancer Center) ;
Chung, D. (Pharmacyclics LLC. AbbVie Company) ;
Lin, J. (Pharmacyclics LLC. AbbVie Company) ;
Gau, L. (Pharmacyclics LLC. AbbVie Company) ;
Chang, B. (Pharmacyclics LLC. AbbVie Company) ;
Cole, G. (Pharmacyclics LLC. AbbVie Company) ;
Hsu, E. (Pharmacyclics LLC. AbbVie Company) ;
James, D.F. (Pharmacyclics LLC. AbbVie Company) ;
Byrd, J.C. (Ohio State University) ;
Universitat Autònoma de Barcelona
In the phase 3 RESONATE study, ibrutinib demonstrated superior progression-free survival (PFS), overall survival (OS) and overall response rate (ORR) compared with ofatumumab in relapsed/refractory CLL patients with high-risk prognostic factors. [...]
2018 - 10.1038/leu.2017.175
Leukemia, Vol. 32 Núm. 1 (january 2018) , p. 83-91
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11 p, 183.8 KB |
Multimodal treatment for smoking cessation with varenicline in alcoholic, methadone-maintained, and psychotic patients : A one-year follow-up
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Raich, Antonia (Universitat de Barcelona) ;
Pinet, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Ballbè, Montse ;
Mondon, Silvia (Hospital Clínic i Provincial de Barcelona) ;
Tejedor, Rosa (Althaia Xarxa Assistencial Universitària de Manresa) ;
Arnau, Anna (Althaia Xarxa Assistencial Universitària de Manresa) ;
Fernández, Esteve (Hospital Universitari de Bellvitge) ;
Cano, Margarita ;
Carcolé, Blanca ;
Fernández, Teresa ;
Martínez, Àngela ;
Nieva, Gemma ;
Roig, Pilar ;
Serra, Imma ;
Serrano, Jaume ;
Universitat Autònoma de Barcelona
Numerous studies have evaluated the efficacy and safety of varenicline for smoking cessation in smokers in the general population and, to a lesser extent, among the psychiatric population. However, few studies have evaluated varenicline in patients with other addictions. [...]
2018 - 10.18332/tid/99541
Tobacco Induced Diseases, Vol. 16 Núm. December (december 2018) , p. 58
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Climate change increases carbon allocation to leaves in early leaf green-up
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Meng, Fandong (Chinese Academy of Sciences. Institute of Tibetan Plateau Research) ;
Hong, Songbai (Peking University. College of Urban and Environmental Sciences) ;
Wang, Jiawei (Peking University. College of Urban and Environmental Sciences) ;
Chen, Anping (Colorado State University. Department of Biology) ;
Zhang, Yao (Sino-French Institute for Earth System Science) ;
Zhang, Yichen (Peking University. College of Urban and Environmental Sciences) ;
Janssens, Ivan (University of Antwerp. Department of Biology) ;
Mao, Jiafu (Oak Ridge National Laboratory) ;
Myneni, Ranga B. (Boston University. Department of Earth and Environment) ;
Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Piao, Shilong (Chinese Academy of Sciences. Institute of Tibetan Plateau Research)
Global greening, characterized by an increase in leaf area index (LAI), implies an increase in foliar carbon (C). Whether this increase in foliar C under climate change is due to higher photosynthesis or to higher allocation of C to leaves remains unknown. [...]
2023 - 10.1111/ele.14205
Ecology letters, Vol. 26, Issue 5 (May 2023) , p. 816-826
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