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62 p, 266.9 KB Importancia de los metaloreguladores Fur y Zur en la virulencia de Salmonella typhimurium / Campoy Sánchez, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Barbé García, Jordi, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
El eje central de la presente Tesis Doctoral ha sido la conexión existente entre la capacidad infectiva de Salmonella typhimurium y el mantenimiento de sus concentraciones intracelulares óptimas de hierro y zinc. [...]
The Fur protein is involved in either iron-uptake or iron-storage regulation. In a fur mutant these systems are deregulated, giving raise an increased free Fe2+ concentration. In this situation the enzymic activity of some proteins like 3',5'- cAMP phosphodiesterase, encoded by cpdA gene, may be stimulated, decreasing the fur mutant final cAMP intracellular concentration. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2003
6 documents

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