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8 p, 1.3 MB Preclinical evaluation of antigen-specific nanotherapy based on phosphatidylserine-liposomes for type 1 diabetes / Villalba Felipe, Adrián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ; Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Perna-Barrull, David (Institut Germans Trias i Pujol) ; Bertran-Cobo, Cesc (Institut Germans Trias i Pujol) ; Ehrenberg, Clara (Institut Germans Trias i Pujol) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Vives Pi, Marta (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of insulin-producing cells. Due to the ability of apoptotic cells clearance to induce tolerance, we previously generated liposomes rich in phophatidylserine (PS) -a feature of apoptotic cells- loaded with insulin peptides to mimic apoptotic beta-cells. [...]
2020 - 10.1080/21691401.2019.1699812
Artificial Cells, Nanomedicine and Biotechnology, Vol. 48, issue 1 (2020) , p. 77-83  
Detailed record - Creative Commons

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