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24 p, 14.0 MB Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor : Morphine and Fentanyl Elicit Different Activation Patterns / Ricarte, Adrián (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Dalton, James A. R.. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències)
Over the past two decades, the opioid epidemic in the United States and Canada has evidenced the need for a better understanding of the molecular mechanisms of medications used to fight pain. Morphine and fentanyl are widely used in opiate-mediated analgesia for the treatment of chronic pain. [...]
2021 - 10.1021/acs.jcim.0c00890
Journal of Chemical Information and Modeling, Vol. 61 Núm. 3 (22 2021) , p. 1251-1274
2 documents
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