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14 p, 3.7 MB Investigating potential inhibitory effect of Uncaria tomentosa (Cat's Claw) against the main protease 3CL pro of SARS-CoV-2 by molecular modeling / Yepes-Pérez, Andres F. (Universidad de Antioquia) ; Herrera-Calderon, Oscar (Universidad Nacional Mayor de San Marcos. Academic Department of Pharmacology, Bromatology and Toxicology (Perú)) ; Sánchez-Aparicio, José-Emilio (Universitat Autònoma de Barcelona. Departament de Química) ; Tiessler-Sala, Laura (Universitat Autònoma de Barcelona. Departament de Química) ; Maréchal, Jean-Didier (Universitat Autònoma de Barcelona. Departament de Química) ; Cardona-G, Wilson (Universidad de Antioquia)
COVID-19 is a disease caused by severe acute respiratory syndrome coronavirus 2. Presently, there is no effective treatment for COVID-19. As part of the worldwide efforts to find efficient therapies and preventions, it has been reported the crystalline structure of the SARS-CoV-2 main protease M pro (also called 3CL pro) bound to a synthetic inhibitor, which represents a major druggable target. [...]
2020 - 10.1155/2020/4932572
Evidence-based Complementary and Alternative Medicine, Vol. 2020 (September 2020) , art. 4932572  
Detailed record - Creative Commons

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