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16 p, 2.5 MB The C-Terminus of Panusin, a Lobster β-Defensin, Is Crucial for Optimal Antimicrobial Activity and Serum Stability / Bello-Madruga, Roberto (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Valle García, Javier (Universitat Pompeu Fabra) ; Jiménez, María Ángeles (Instituto de Química Física Blas Cabrera) ; Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Montero-Alejo, Vivian (Center for Pharmaceutical Research and Development (La Habana, Cuba)) ; Andreu Martínez, David (Universitat Pompeu Fabra)
β-defensins are one of the most abundant and studied families of antimicrobial peptides (AMPs). Because of their selective toxicity to bacterial membranes and a broad spectrum of microbicidal action, β-defensins are regarded as potential therapeutic agents. [...]
2023 - 10.3390/pharmaceutics15061777
Pharmaceutics, Vol. 15 (june 2023)  

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