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Results overview: Found 5 records in 0.04 seconds.
Articles, 5 records found
Articles 5 records found  
1.
Human lysyl oxidase over-expression enhances baseline cardiac oxidative stress but does not aggravate ros generation or infarct size following myocardial ischemia-reperfusion / Valls-Lacalle, Laura (Instituto de Salud Carlos III) ; Puertas Umbert, Lídia (Institut d'Investigació Biomèdica Sant Pau) ; Varona, Saray (Institut d'Investigació Biomèdica Sant Pau) ; Martínez-González, José (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Rodríguez-Sinovas, Antonio (Instituto de Salud Carlos III) ; Universitat Autònoma de Barcelona
Lysyl oxidase (LOX) is an enzyme critically involved in collagen maturation, whose activity releases HO as a by-product. Previous studies demonstrated that LOX over-expression enhances reactive oxygen species (ROS) production and exacerbates cardiac remodeling induced by pressure overload. [...]
2022 - 10.3390/antiox11010075
Antioxidants, Vol. 11 Núm. 1 (january 2022) , p. 75  
Detailed record - Creative Commons
2.
64 p, 3.2 MB Connexins in the Heart : Regulation, Function and Involvement in Cardiac Disease / Rodríguez-Sinovas, Antonio (Universitat Autònoma de Barcelona. Departament de Medicina) ; Sánchez, Jose Antonio (Universitat Autònoma de Barcelona. Departament de Medicina) ; Valls-Lacalle, Laura (Universitat Autònoma de Barcelona. Departament de Medicina) ; Consegal, Marta (Universitat Autònoma de Barcelona. Departament de Medicina) ; Ferreira-Gonzalez, Ignacio (Universitat Autònoma de Barcelona. Departament de Medicina)
Connexins are a family of transmembrane proteins that play a key role in cardiac physiology. Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes, allowing the existence of electrical coupling. [...]
2021 - 10.3390/ijms22094413
International journal of molecular sciences, Vol. 22 (april 2021)  
Detailed record - Creative Commons
3.
10 p, 1.7 MB Selective Inhibition of Succinate Dehydrogenase in Reperfused Myocardium with Intracoronary Malonate Reduces Infarct Size / Valls-Lacalle, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Miró-Casas, Elisabet (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ruiz Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez-Sinovas, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Inhibition of succinate dehydrogenase (SDH) with malonate during reperfusion reduces infarct size in isolated mice hearts submitted to global ischemia. However, malonate has toxic effects that preclude its systemic administration in animals. [...]
2018 - 10.1038/s41598-018-20866-4
Scientific reports, Vol. 8 (february 2018)  
Detailed record - Creative Commons
4.
1 p, 665.2 KB Author Correction : Selective Inhibition of Succinate Dehydrogenase in Reperfused Myocardium with Intracoronary Malonate Reduces Infarct Size / Valls-Lacalle, Laura (Hospital Universitari Vall d'Hebron) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron) ; Miró-Casas, Elisabet (Hospital Universitari Vall d'Hebron) ; Ruiz-Meana, Marisol (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Rodríguez-Sinovas, Antonio (Hospital Universitari Vall d'Hebron) ; García-Dorado, David (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
2019 - 10.1038/s41598-019-42591-2
Scientific reports, Vol. 9 (april 2019)  
Detailed record - Creative Commons
5.
10 p, 2.0 MB Connexin 43 deficiency is associated with reduced myocardial scar size and attenuated tgfβ1 signaling after transient coronary occlusion in conditional knock-out mice / Valls-Lacalle, Laura (Universitat Autònoma de Barcelona. Departament de Medicina) ; Consegal, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ruiz Meana, Marisol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Benito, Begoña (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Inserte, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferreira-Gonzalez, Ignacio (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rodríguez-Sinovas, Antonio (Universitat Autònoma de Barcelona. Departament de Medicina)
Previous studies demonstrated a reduction in myocardial scar size in heterozygous Cx43-mice subjected to permanent coronary occlusion. However, patients presenting with ST segment elevation myocardial infarction often undergo rapid coronary revascularization leading to prompt restoration of coronary flow. [...]
2020 - 10.3390/biom10040651
Biomolecules, Vol. 10 Núm. 4 (april 2020) , p. 651  
Detailed record - Creative Commons

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