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1.
7 p, 998.5 KB Assessing the electrochemical CO2 reduction reaction performance requires more than reporting coulombic efficiency / Izadi, Paniz (Helmholtz Centre for Environmental Research (Leipzig, Alemanya)) ; Song,Jia (Vlaamse Instelling voor Technologisch Onderzoek) ; Singh,Chandani (Vlaamse Instelling voor Technologisch Onderzoek) ; Pant, Deepak (Vlaamse Instelling voor Technologisch Onderzoek) ; Harnisch, Falk (Helmholtz Centre for Environmental Research (Leipzig, Alemanya))
Reporting coulombic efficiency (CE) is the common way to assess the performance of electrochemical carbon dioxide (CO2) reduction reaction (eCO2RR) in literature, whereas its carbon conversion efficiency (CCE) is frequently neglected. [...]
2024 - 10.1002/aesr.202400031
Advanced Energy & Sustainability research, (February 2024) , art. 2400031
2 documentos
2.
10 p, 1.4 MB Cardiac and pulmonary findings in dysferlinopathy : A 3-year, longitudinal study / Moore, Ursula (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Fernandez-Torron, Roberto (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Jacobs, Marni (Pediatrics. Epidemiology and Biostatistics. George Washington University) ; Gordish-Dressman, Heather (Pediatrics. Epidemiology and Biostatistics. George Washington University) ; Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; James, Meredith K (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Mayhew, Anna G. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Harris, Elizabeth (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Guglieri, Michela (Newcastle University) ; Rufibach, Laura E. (The Jain Foundation) ; Feng, Jia (Center for Translational Science. Division of Biostatistics and Study Methodology. Children's National Health System) ; Blamire, Andrew (Translational and Clinical Research Institute. Newcastle University) ; Carlier, Pierre G. (University Paris-Saclay. CEA. DRF. Service Hospitalier Frederic Joliot) ; Spuler, Simone (Charite Muscle Research Unit. Experimental and Clinical Research Center. a joint cooperation of the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine) ; Day, John W (Stanford University School of Medicine) ; Jones, Kristi J. (The Children's Hospital at Westmead. and The University of Sydney) ; Bharucha-Goebel, Diana (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Salort-Campana, Emmanuelle (Service des maladies neuromusculaire et de la SLA. Hôpital de La Timone) ; Pestronk, Alan (Washington University School of Medicine) ; Walter, Maggie C. (Friedrich-Baur-Institute. Department of Neurology. Ludwig-Maximilians-University of Munich) ; Paradas, Carmen (Instituto de Biomedicina de Sevilla) ; Stojkovic, Tanya (Sorbonne Université) ; Mori-Yoshimura, Madoka (National Center of Neurology and Psychiatry Tokyo) ; Bravver, Elena (Neuroscience Institute. Carolinas Neuromuscular/ALS-MDA Center. Carolinas HealthCare System) ; Pegoraro, Elena (Department of Neuroscience. University of Padova) ; Lowes, Linda Pax (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ; Mendell, Jerery R. (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ; Bushby, Kate (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Bourke, John (Department of Cardiology. Freeman Hospital. NUTH NHS Hospitals Foundation Trust) ; Straub, Volker (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust)
Introduction/Aims: There is debate about whether and to what extent either respiratory or cardiac dysfunction occurs in patients with dysferlinopathy. This study aimed to establish definitively whether dysfunction in either system is part of the dysferlinopathy phenotype. [...]
2022 - 10.1002/mus.27524
Muscle & nerve, Vol. 65 Núm. 5 (may 2022) , p. 531-540  
3.
10 p, 1.7 MB Assessing the Relationship of Patient Reported Outcome Measures With Functional Status in Dysferlinopathy : A Rasch Analysis Approach / Mayhew, Anna G. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; James, Meredith K. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Moore, Ursula (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Sutherland, Helen (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Jacobs, Marni (Pediatrics. Epidemiology and Biostatistics. George Washington University) ; Feng, Jia (Center for Translational Science. Division of Biostatistics and Study Methodology. Children's National Health System) ; Lowes, Linda Pax (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ; Alfano, Lindsay N. (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ; Muni Lofra, Robert (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Rufibach, Laura E. (The Jain Foundation) ; Rose, Kristy (The Children's Hospital at Westmead. The University of Sydney) ; Duong, Tina (Lucile Salter Packard Children's Hospital at Stanford. Neurology) ; Bello, Luca (Department of Neuroscience. University of Padova) ; Pedrosa-Hernández, Irene (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Holsten, S. (Neuroscience Institute. Carolinas Neuromuscular/ALS-MDA Center. Carolinas HealthCare System) ; Sakamoto, C. (Department of Physical Rehabilitation. National Center Hospital. National Center of Neurology and Psychiatry Tokyo) ; Canal, Aurélie (Institut de Myologie. AP-HP. GH Pitié-Salpêtrière) ; Sánchez-Aguilera Práxedes, N. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Thiele, S. (Department of Neurology. Friedrich-Baur-Institute. Ludwig-Maximilians-University of Munich) ; Siener, C. (Department of Neurology. Washington University School of Medicine) ; Vandevelde, B. (Service des Maladies Neuromusculaire et de la SLA. Hôpital de La Timone) ; DeWolf, Brittney (Cooperative International Neuromuscular Research Group. Children's National Health System) ; Maron, E. (ELAN-PHYSIO. Praxis für Physiotherapie Maron) ; Gordish-Dressman, H. (Pediatrics. Epidemiology and Biostatistics. George Washington University) ; Hilsden, H. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Guglieri, M. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust) ; Hogrel, J.Y. (Institut de Myologie. AP-HP. GH Pitié-Salpêtrière) ; Blamire, Andrew (Magnetic Resonance Centre. Institute for Cellular Medicine. Newcastle University) ; Carlier, Pierre G. (Pitié-Salpêtrière University Hospital) ; Spuler, S. (Charite Muscle Research Unit. Experimental and Clinical Research Center. A Joint Cooperation of the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine) ; Day, John W. (Stanford University School of Medicine) ; Jones, K.J. (The Children's Hospital at Westmead. The University of Sydney) ; Bharucha-Goebel, Diana (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Salort-Campana, E. (Service des Maladies Neuromusculaire et de la SLA. Hôpital de La Timone) ; Pestronk, Alan (Washington University School of Medicine) ; Walter, M.C. (Department of Neurology. Friedrich-Baur-Institute. Ludwig-Maximilians-University of Munich) ; Paradas, C. (Instituto de Biomedicina de Sevilla) ; Stojkovic, T. (Institut de Myologie. AP-HP. GH Pitié-Salpêtrière) ; Mori-Yoshimura, Madoka (National Center of Neurology and Psychiatry Tokyo) ; Bravver, Elena (Neuroscience Institute. Carolinas Neuromuscular/ALS-MDA Center. Carolinas HealthCare System) ; Diaz-Manera, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Pegoraro, Elena (University of Padova) ; Mendell, J. R. (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ; Jain COS Consortium, None (The Abigail Wexner Research Institute at Nationwide Children's Hospital) ; Straub, V. (The John Walton Muscular Dystrophy Research Centre. Translational and Clinical Research Institute. Newcastle University and Newcastle Hospitals NHS Foundation Trust)
Dysferlinopathy is a muscular dystrophy with a highly variable functional disease progression in which the relationship of function to some patient reported outcome measures (PROMs) has not been previously reported. [...]
2022 - 10.3389/fneur.2022.828525
Frontiers in neurology, Vol. 13 (october 2022) , p. 828525  
4.
19 p, 1.3 MB State-of-the-art of lumbar puncture and its place in the journey of patients with Alzheimer's disease / Hampel, Harald (Eisai Inc. Neurology Business Group) ; Shaw, Leslie M. (Perelman School of Medicine. Department of Pathology and Laboratory Medicine. University of Pennsylvania) ; Aisen, Paul (USC Alzheimer's Therapeutic Research Institute) ; Chen, Christopher (Memory Aging and Cognition Centre. Departments of Pharmacology and Psychological Medicine. Yong Loo Lin School of Medicine. National University of Singapore) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Iwatsubo, Takeshi (Department of Neuropathology. Graduate School of Medicine. The University of Tokyo) ; Iwata, Atsushi (Tokyo Metropolitan Geriatric Hospital) ; Yamada, Masahito (Department of Neurology and Neurobiology of Aging. Kanazawa University Graduate School of Medical Science) ; Ikeuchi, Takeshi (Department of Molecular Genetics. Brain Research Institute. Niigata University) ; Jia, Jianping (Innovation Center for Neurological Disorders. Department of Neurology. Xuan Wu Hospital. Capital Medical University) ; Wang, Huali (Dementia Care and Research Center. Peking University Institute of Mental Health (Sixth Hospital). Beijing Dementia Key Lab. National Clinical Research Center for Mental Disorders) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers (AUMC)) ; Peskind, Elaine (VA Northwest Mental Illness Research. Education and Clinical Center. VA Puget Sound Health Care System. Department of Psychiatry and Behavioral Sciences. University of Washington School of Medicine) ; Blennow, Kaj (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Cummings, Jeffrey (Chambers-Grundy Center for Transformative Neuroscience. Department of Brain Health. School of Integrated Health Sciences. University of Nevada Las Vegas (UNLV)) ; Vergallo, Andrea (Eisai Inc. Neurology Business Group) ; Universitat Autònoma de Barcelona
Recent advances in developing disease-modifying therapies (DMT) for Alzheimer's disease (AD), and the recognition that AD pathophysiology emerges decades before clinical symptoms, necessitate a paradigm shift of health-care systems toward biomarker-guided early detection, diagnosis, and therapeutic decision-making. [...]
2022 - 10.1002/alz.12372
Alzheimer's & Dementia, Vol. 18 Núm. 1 (january 2022) , p. 159-177  
5.
9 p, 1.5 MB The use of lumbar puncture and safety recommendations in Alzheimer's disease : a plain language summary / Hampel, Harald (Eisai Inc. Neurology Business Group) ; Elhage, Aya (Eisai Inc. Neurology Business Group) ; Shaw, Leslie M. (Perelman School of Medicine. Department of Pathology & Laboratory Medicine. University of Pennsylvania) ; Aisen, Paul (Usc Alzheimer's Therapeutic Research Institute) ; Chen, Christopher (Memory Aging & Cognition Centre. Departments of Pharmacology & Psychological Medicine. Yong Loo Lin School of Medicine. National University of Singapore) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Iwatsubo, Takeshi (Department of Neuropathology. Graduate School of Medicine. The University of Tokyo) ; Iwata, Atsushi (Tokyo Metropolitan Geriatric Hospital) ; Yamada, Masahito (Department of Neurology & Neurological Science. Tokyo Medical & Dental University) ; Ikeuchi, Takeshi (Department of Molecular Genetics. Brain Research Institute. Niigata University) ; Jia, Jianping (Innovation Center for Neurological Disorders. Department of Neurology. Xuan Wu Hospital. Capital Medical University) ; Wang, Huali (Dementia Care & Research Center. Peking University Institute of Mental Health (Sixth Hospital). Beijing Dementia Key Lab. National Clinical Research Center for Mental Disorders) ; Teunissen, Charlotte E. (Amsterdam University Medical Centers (AUMC)) ; Peskind, Elaine (Va Northwest Mental Illness Research. Education & Clinical Center. Va Puget Sound Health Care System. Department of Psychiatry & Behavioral Sciences. University of Washington School of Medicine) ; Blennow, Kaj (Clinical Neurochemistry Laboratory. Sahlgrenska University Hospital) ; Cummings, Jeffrey (Chambers-Grundy Center for Transformative Neuroscience. Department of Brain Health. School of Integrated Health Sciences. University of Nevada Las Vegas (UNLV)) ; Vergallo, Andrea (Eisai Inc. Neurology Business Group) ; Universitat Autònoma de Barcelona
What is this summary about? This is a plain language summary of an article published in Alzheimer's & Dementia. It looks at a type of test called a lumbar puncture (also known as spinal tap) used in people suspected of having Alzheimer's disease or some other form of dementia. [...]
2022 - 10.2217/nmt-2022-0012
Neurodegenerative Disease Management, Vol. 12 Núm. 5 (january 2022) , p. 221-229  
6.
42 p, 2.1 MB Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis / Kanoni, Stavroula (Queen Mary University of London) ; Graham, Sarah E. (University of Michigan) ; Wang, Yuxuan (Boston University School of Public Health) ; Surakka, Ida (University of Michigan) ; Ramdas, Shweta (University of Pennsylvania) ; Zhu, Xiang (Stanford University) ; Clarke, Shoa L. (Stanford University School of Medicine) ; Bhatti, Konain Fatima (Queen Mary University of London) ; Vedantam, Sailaja (Broad Institute of MIT and Harvard) ; Winkler, Thomas W. (University of Regensburg) ; Locke, Adam E. (Washington University) ; Marouli, Eirini (Queen Mary University of London) ; Zajac, Greg J. M. (University of Michigan) ; Wu, Kuan-Han H. (University of Michigan) ; Ntalla, Ioanna (Queen Mary University of London) ; Hui, Qin (Atlanta VA Health Care System) ; Klarin, Derek (Stanford University School of Medicine) ; Hilliard, Austin T. (VA Palo Alto Health Care Systems) ; Wang, Zeyuan (Atlanta VA Health Care System) ; Xue, Chao (University of Michigan) ; Thorleifsson, Gudmar (deCODE Genetics/Amgen) ; Helgadottir, Anna (deCODE Genetics/Amgen) ; Gudbjartsson, Daniel F. (University of Iceland) ; Holm, Hilma (deCODE Genetics/Amgen) ; Olafsson, Isleifur (Landspitali - National University Hospital of Iceland) ; Hwang, Mi Yeong (National Institute of Health) ; Han, Sohee (National Institute of Health) ; Akiyama, Masato (Kyushu University) ; Sakaue, Saori (The University of Tokyo) ; Terao, Chikashi (RIKEN Center for Integrative Medical Sciences) ; Kanai, Masahiro (Harvard Medical School) ; Zhou, Wei (Massachusetts General Hospital) ; Brumpton, Ben M. (St Olav's University Hospital) ; Rasheed, Humaira (University of Oslo) ; Havulinna, Aki S. (Finnish Institute for Health and Welfare) ; Veturi, Yogasudha (University of Pennsylvania) ; Pacheco, Jennifer Allen (Northwestern University) ; Rosenthal, Elisabeth A. (University of Washington) ; Lingren, Todd (Cincinnati Children's Hospital Medical Center) ; Feng, QiPing (Vanderbilt University Medical Center) ; Kullo, Iftikhar J. (Mayo Clinic) ; Narita, Akira (Tohoku Medical Megabank Organization) ; Takayama, Jun (Tohoku Medical Megabank Organization) ; Martin, Hilary C. (Wellcome Trust Sanger Institute (Regne Unit)) ; Hunt, Karen A. (Queen Mary University of London) ; Trivedi, Bhavi (Queen Mary University of London) ; Haessler, Jeffrey (Fred Hutchinson Cancer Center) ; Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Bradford, Yuki (University of Pennsylvania) ; Miller, Jason E. (University of Pennsylvania) ; Campbell, Archie (University of Edinburgh) ; Lin, Kuang (University of Oxford) ; Millwood, Iona Y. (University of Oxford) ; Rasheed, Asif (Center for Non-Communicable Diseases) ; Hindy, George (Qatar University College of Medicine) ; Faul, Jessica D. (University of Michigan) ; Zhao, Wei (University of Michigan) ; Weir, David R. (University of Michigan) ; Turman, Constance (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Huang, Hongyan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Graff, Mariaelisa (University of North Carolina) ; Choudhury, Ananyo (University of the Witwatersrand) ; Sengupta, Dhriti (University of the Witwatersrand) ; Mahajan, Anubha (University of Oxford) ; Brown, Michael R. (The University of Texas Health Science Center at Houston) ; Zhang, Weihua (London North West University Healthcare NHS Trust) ; Yu, Ketian (University of Michigan) ; Schmidt, Ellen M. (University of Michigan) ; Pandit, Anita (University of Michigan) ; Gustafsson, S (Uppsala University) ; Yin, Xianyong (University of Michigan) ; Luan, Jian'an (University of Cambridge School of Clinical Medicine) ; Zhao, Jing-Hua (University of Cambridge) ; Matsuda, Fumihiko (Kyoto University Graduate School of Medicine) ; Jang, Hye-Mi (National Institute of Health) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Medina-Gomez, Carolina (University Medical Center Rotterdam) ; Pitsillides, Achilleas (Boston University School of Public Health) ; Hottenga, Jouke Jan (Amsterdam Public Health Research Institute) ; Wood, Andrew R. (University of Exeter Medical School) ; Ji, Yingji (University of Exeter Medical School) ; Gao, Zishan (German Research Center for Environmental Health) ; Haworth, Simon (University of Bristol) ; Yousri, Noha A. (Alexandria University) ; Mitchell, Ruth E. (University of Bristol) ; Chai, Jin Fang (National University of Singapore and National University Health System) ; Aadahl, Mette (University of Copenhagen) ; Bjerregaard, Anne A. (Bispebjerg and Frederiksberg Hospital) ; Yao, Jie (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Manichaikul, Ani (University of Virginia) ; Hwu, Chii-Min (Taipei Veterans General Hospital) ; Hung, Yi-Jen (National Defense Medical Center) ; Warren, Helen R. (Queen Mary University of London) ; Ramirez, Julia (Universidad de Zaragoza) ; Bork-Jensen, Jette (University of Copenhagen) ; Kårhus, Line L. (Bispebjerg and Frederiksberg Hospital) ; Goel, Anuj (University of Oxford) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Noordam, Raymond (Leiden University Medical Center) ; Mauro, Pala (Consiglio Nazionale Delle Ricerche) ; Matteo, Floris (Università Degli Studi Di Sassari) ; McDaid, Aaron F. (Swiss Institute of Bioinformatics) ; Marques-Vidal, Pedro (Lausanne University Hospital) ; Wielscher, Matthias (Imperial College London) ; Trompet, Stella (Leiden University Medical Center) ; Sattar, Naveed (BHF Glasgow Cardiovascular Research Centre) ; Møllehave, Line T. (Bispebjerg and Frederiksberg Hospital) ; Munz, Matthias (University of Lübeck) ; Zeng, Lingyao (Partner Site Munich Heart Alliance) ; Huang, Jianfeng (Fuwai Hospital) ; Yang, Bin (Fuwai Hospital) ; Poveda, Alaitz (Lund University Diabetes Center) ; Kurbasic, Azra (Lund University Diabetes Center) ; Lamina, Claudia (German Chronic Kidney Disease Study) ; Forer, Lukas (German Chronic Kidney Disease Study) ; Scholz, Markus (University of Leipzig) ; Galesloot, Tessel E. (Radboud University Medical Center) ; Bradfield, Jonathan Paul (Quantinuum Research LLC) ; Ruotsalainen, Sanni E. (University of Helsinki) ; Daw, E. Warwick (Washington University School of Medicine) ; Zmuda, Joseph M. (University of Pittsburgh) ; Mitchell, Jonathan S. (Affiliated Institute of the University of Lübeck) ; Fuchsberger, Christian (Affiliated Institute of the University of Lübeck) ; Christensen, Henry (Lillebaelt Hospital) ; Brody, Jennifer A. (University of Washington) ; Vazquez-Moreno, Miguel (Centro Medico Nacional Siglo XXI) ; Feitosa, Mary F. (Washington University School of Medicine) ; Wojczynski, Mary K. (Washington University School of Medicine) ; Wang, Zhe (The Charles Bronfman Institute for Personalized Medicine) ; Preuss, Michael H. (The Charles Bronfman Institute for Personalized Medicine) ; Mangino, Massimo (NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust) ; Christofidou, Paraskevi (King's College London) ; Verweij, Niek (University of Groningen) ; Benjamins, Jan W. (University of Groningen) ; Engmann, Jorgen (University College London) ; Tsao, Noah L. (University of Pennsylvania) ; Verma, Anurag (University of Pennsylvania) ; Slieker, Roderick C. (Leiden University Medical Center) ; Lo, Ken Sin (Montreal Université de Montréal) ; Zilhao, Nuno R. (Icelandic Heart Association) ; Le, Phuong (University of Toronto at Mississauga) ; Kleber, Marcus E. (SYNLAB MVZ Humangenetik Mannheim GmbH) ; Delgado, Graciela E. (Heidelberg University) ; Huo, Shaofeng (University of Chinese Academy of Sciences) ; Ikeda, Daisuke D. (Tokushima Research Institute) ; Iha, Hiroyuki (Tokushima Research Institute) ; Yang, Jian (The University of Queensland) ; Liu, Jun (University Medical Center Rotterdam) ; Demirkan, Ayşe (University of Surrey) ; Leonard, Hampton L. (Data Tecnica International) ; Marten, Jonathan (University of Edinburgh) ; Frank, Mirjam (University of Duisburg-Essen) ; Schmidt, Börge (University of Duisburg-Essen) ; Smyth, Laura J. (Queen's University of Belfast) ; Cañadas-Garre, Marisa (Instituto de Investigación Biosanitaria de Granada) ; Wang, Chaolong (Genome Institute of Singapore) ; Nakatochi, Masahiro (Nagoya University Graduate School of Medicine) ; Wong, Andrew (MRC Unit for Lifelong Health and Ageing at UCL) ; Hutri-Kähönen, Nina (Tampere University) ; Sim, Xueling (National University of Singapore and National University Health System) ; Xia, Rui (University of Texas Health Science Center at Houston) ; Huerta-Chagoya, Alicia (Instituto de Investigaciones Biomédicas (Mèxic)) ; Fernandez-Lopez, Juan Carlos (Instituto Nacional de Medicina Genómica) ; Lyssenko, Valeriya (University of Bergen) ; Nongmaithem, Suraj S. (Academy of Scientific and Innovative Research (AcSIR)) ; Bayyana, Swati (Academy of Scientific and Innovative Research (AcSIR)) ; Stringham, Heather M. (University of Michigan.) ; Irvin, Marguerite R. (University of Alabama at Birmingham) ; Oldmeadow, Christopher (Hunter Medical Research Institute) ; Kim, Han-Na (SAIHST, Sungkyunkwan University) ; Ryu, Seungho (Kangbuk Samsung Hospital) ; Timmers, Paul R. H. J. (University of Edinburgh) ; Arbeeva, Liubov (University of North Carolina) ; Dorajoo, Rajkumar (Duke-NUS Medical School) ; Lange, Leslie A. (University of Colorado) ; Prasad, Gauri (CSIR-Human Resource Development Centre) ; Lorés-Motta, Laura (Radboud University Nijmegen Medical Center) ; Pauper, Marc (Radboud University Nijmegen Medical Center) ; Long, Jirong (Vanderbilt University Medical Center) ; Li, Xiaohui (Harbor-UCLA Medical Center) ; Theusch, Elizabeth (University of California San Francisco) ; Takeuchi, Fumihiko (National Center for Global Health and Medicine) ; Spracklen, Cassandra N. (University of Massachusetts-Amherst) ; Loukola, Anu (University of Helsinki) ; Bollepalli, Sailalitha (University of Helsinki) ; Warner, Sophie C. (Glenfield Hospital) ; Wang, Ya Xing (Beijing Institute of Ophthalmology) ; Wei, Wen B. (Beijing Tongren Eye Center) ; Nutile, Teresa (Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" - CNR) ; Ruggiero, Daniela (IRCCS Neuromed) ; Sung, Yun Ju (Washington University) ; Chen, Shufeng (Fuwai Hospital) ; Liu, Fangchao (Fuwai Hospital) ; Yang, Jingyun (Rush University Medical Center) ; Kentistou, Katherine A. (University of Edinburgh) ; Banas, Bernhard (University Hospital Regensburg) ; Nardone, Giuseppe Giovanni (IRCCS Burlo Garofolo) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Bielak, Lawrence F. (University of Michigan) ; Smith, Jennifer A. (University of Michigan) ; Hebbar, Prashantha (Dasman Diabetes Institute) ; Farmaki, Aliki-Eleni (University College London) ; Hofer, Edith (Medical University of Graz) ; Lin, Maoxuan (Massachusetts General Hospital Cancer Center) ; Concas, Maria Pina (IRCCS Burlo Garofolo) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research) ; van der Most, Peter J (University of Groningen) ; Pitkänen, Niina (University of Turku and Turku University Hospital) ; Cade, Brian E. (Harvard Medical School) ; van der Laan, Sander W (University Medical Center Utrecht) ; Chitrala, Kumaraswamy Naidu (University of Houston-Sugarland) ; Weiss, Stefan (University of Greifswald and University Medicine Greifswald) ; Bentley, Amy R. (National Human Genome Research Institute) ; Doumatey, Ayo P. (National Human Genome Research Institute) ; Adeyemo, Adebowale A. (National Human Genome Research Institute) ; Lee, Jong Young (Soonchunhyang Mirai Medical Center 173) ; Petersen, Eva R. B. (Hospital of Southern Jutlandy and Immunology) ; Nielsen, Aneta A. (Lillebaelt Hospital) ; Choi, Hyeok Sun (Hallym University) ; Nethander, Maria (University of Gothenburg) ; Freitag-Wolf, Sandra (Kiel University) ; Southam, Lorraine (Institute of Translational Genomics) ; Rayner, Nigel W. (University of Oxford) ; Wang, Carol A (University of Newcastle) ; Lin, Shih-Yi (National Defense Medical Center) ; Wang, Jun-Sing (National Yang Ming Chiao Tung University) ; Couture, Christian (Université Laval) ; Lyytikäinen, Leo-Pekka (Finnish Cardiovascular Research Center - Tampere) ; Nikus, Kjell (Finnish Cardiovascular Research Center - Tampere) ; Cuellar-Partida, Gabriel (University of Queensland Diamantina Institute) ; Vestergaard, Henrik (Bornholms Hospital) ; Hidalgo, Bertha (University of Alabama at Birmingham) ; Giannakopoulou, Olga (Queen Mary University of London) ; Cai, Qiuyin (Vanderbilt University Medical Center) ; Obura, Morgan O. (Amsterdam Public Health Research Institute) ; van Setten, Jessica (University Medical Center Utrecht) ; Li, Xiaoyin (Case Western Reserve University) ; Liang, Jingjing (Case Western Reserve University) ; Tang, Hua (Stanford University School of Medicine Stanford) ; Terzikhan, Natalie (University Medical Center Rotterdam) ; Shin, Jae Hun (Hallym University) ; Jackson, Rebecca D. (Ohio State University) ; Reiner, Alexander P. (University of Washington) ; Martin, Lisa Warsinger (George Washington University) ; Chen, Zhengming (University of Oxford) ; Li, Liming (Peking University Health Science Center) ; Kawaguchi, Takahisa (Kyoto University Graduate School of Medicine) ; Thiery, Joachim (University Hospital Leipzig) ; Bis, Joshua C (University of Washington) ; Launer, Lenore J. (National Institute On Aging) ; Li, Huaixing (University of Chinese Academy of Sciences) ; Nalls, Mike A. (Data Tecnica International) ; Raitakari, Olli T. (Turku University Hospital (Finlàndia)) ; Ichihara, Sahoko (Jichi Medical University School of Medicine) ; Wild, Sarah H. (University of Edinburgh) ; Nelson, Christopher P. (NIHR Leicester Biomedical Research Centre) ; Campbell, Harry (University of Edinburgh) ; Jäger, Susanne (German Center for Diabetes Research (DZD)) ; Nabika, Toru (Shimane University School of Medicine) ; Al-Mulla, Fahd (Dasman Diabetes Institute) ; Niinikoski, Harri (University of Turku) ; Braund, Peter S. (NIHR Leicester Biomedical Research Centre) ; Kolcic, Ivana (University of Split School of Medicine) ; Kovacs, Peter (University of Leipzig Medical Center) ; Giardoglou, Tota (Harokopio University) ; Katsuya, Tomohiro (Osaka University Graduate School of Medicine) ; de Kleijn, Dominique (University Medical Center Utrecht) ; de Borst, Gert J. (University Medical Center Utrecht) ; Kim, Eung Kweon (Yonsei University College of Medicine) ; Adams, Hieab H. H. (Universidad Adolfo Ibáñez) ; Ikram, M. Arfan (University Medical Center Rotterdam) ; Zhu, X (Case Western Reserve University) ; Asselbergs, Folkert W. (University Medical Center Utrecht) ; Kraaijeveld, Adriaan O. (University Medical Center Utrecht) ; Beulens, Joline W. J. (University Medical Centre Utrecht) ; Shu, Xiao-Ou (Vanderbilt University Medical Center) ; Rallidis, Loukianos S. (National and Kapodistrian University of Athens) ; Pedersen, Oluf (University of Copenhagen) ; Hansen, Torben (University of Copenhagen) ; Mitchell, Paul (University of Sydney) ; Hewitt, Alex W. (University of Melbourne) ; Kähönen, Mika (Tampere University) ; Pérusse, Louis (Institute of Nutrition and Functional Foods (INAF)) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Tönjes, Anke (University of Leipzig Medical Center) ; Chen, Yii Der Ida (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Pennell, Craig E. (University of Newcastle) ; Mori, Trevor A. (The University of Western Australia) ; Lieb, Wolfgang (Kiel University) ; Franke, Andre (Kiel University) ; Ohlsson, Claes (Sahlgrenska University Hospital (Suècia)) ; Mellström, Dan (University of Gothenburg) ; Cho, Yoon Shin (Hallym University) ; Lee, Hyejin (EwhaWomans University School of Medicine) ; Yuan, Jian-Min (University of Pittsburgh) ; Koh, Woon-Puay (Singapore Institute for Clinical Sciences) ; Rhee, Sang Youl (Kyung Hee University School of Medicine) ; Woo, Jeong-Taek (Kyung Hee University School of Medicine) ; Heid, Iris M. (University of Regensburg) ; Stark, Klaus J. (University of Regensburg) ; Zimmermann, Martina E. (University of Regensburg) ; Völzke, Henry (University Medicine Greifswald) ; Homuth, Georg (University of Greifswald and University Medicine Greifswald) ; Evans, Michele K. (National Institute On Aging Intramural Research Program) ; Zonderman, Alan B. (National Institute On Aging Intramural Research Program) ; Polasek, Ozren (Algebra University College) ; Pasterkamp, Gerard (University Medical Center Utrecht) ; Hoefer, Imo E. (University Medical Center Utrecht) ; Redline, Susan (Harvard Medical School) ; Pahkala, Katja (University of Turku) ; Oldehinkel, Albertine J. (University of Groningen) ; Snieder, Harold (University Medical Center Groningen) ; Biino, Ginevra (National Research Council of Italy) ; Schmidt, Reinhold (Medical University of Graz) ; Schmidt, Helena (Medical University of Graz) ; Bandinelli, Stefania (Local Health Unit Toscana Centro) ; Dedoussis, George (Harokopio University of Athens) ; Thanaraj, Thangavel Alphonse (Dasman Diabetes Institute. Department of Genetics and Bioinformatics) ; Kardia, Sharon L. R. (University of Michigan) ; Peyser, Patricia A. (University of Michigan) ; Kato, Norihiro (National Center for Global Health and Medicine) ; Schulze, Matthias B. (University of Potsdam) ; Girotto, Giorgia (University of Trieste) ; Böger, Carsten A. (KfH Kidney Center Traunstein) ; Jung, Bettina (KfH Kidney Center Traunstein) ; Joshi, Peter K. (University of Edinburgh) ; Bennett, David A. (Rush University Medical Center) ; De Jager, Philip L. (Columbia University Medical Center) ; Lu, Xiangfeng (Fuwai Hospital) ; Mamakou, Vasiliki (Dromokaiteio Psychiatric Hospital) ; Brown, Morris (Queen Mary University of London) ; Caulfield, Mark J. (Queen Mary University of London) ; Munroe, Patricia B. (Queen Mary University of London) ; Guo, Xiuqing (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Ciullo, Marina (IRCCS Neuromed) ; Jonas, Jost B. (Privatpraxis Prof Jonas Und Dr Panda-Jonas) ; Samani, Nilesh J. (NIHR Leicester Biomedical Research Centre) ; Kaprio, Jaakko (University of Helsinki) ; Pajukanta, Päivi (University of California) ; Tusié-Luna, Teresa (Instituto de Investigaciones Biomédicas UNAM/ Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ; Aguilar-Salinas, Carlos Alberto (Instituto Nacional de Ciencias Médicas Y Nutrición Salvador Zubirán) ; Adair, Linda S. (University of North Carolina) ; Bechayda, Sonny Augustin (University of San Carlos) ; de Silva, H. Janaka (University of Kelaniya) ; Wickremasinghe, Ananda R. (University of Kelaniya) ; Krauss, Ronald M. (Children's Hospital Oakland Research Institute) ; Wu, Jer-Yuarn (Institute of Biomedical Sciences) ; Zheng, Wei (Vanderbilt University Medical Center) ; Hollander, Anneke Iden (Radboud University Nijmegen Medical Center) ; Bharadwaj, Dwaipayan (Jawaharlal Nehru University) ; Correa, Adolfo (University of Mississippi Medical Center) ; Wilson, James G. (University of Mississippi Medical Center) ; Lind, Lars (Uppsala University) ; Heng, Chew-Kiat (Yong Loo Lin School of Medicine) ; Nelson, Amanda E. (University of North Carolina) ; Golightly, Yvonne M. (University of North Carolina) ; Wilson, James F. (University of Edinburgh) ; Penninx, Brenda (Vrije Universiteit Amsterdam) ; Kim, Hyung-Lae (Ewha Womans University) ; Attia, John (University of Newcastle) ; Scott, Rodney J. (University of Newcastle) ; Rao, D. C. (Washington University School of Medicine) ; Arnett, Donna K. (University of South Carolina) ; Hunt, Steven C. (University of Utah) ; Walker, Mark (Institute of Cellular Medicine (Diabetes)) ; Koistinen, Heikki A. (Minerva Foundation Institute for Medical Research) ; Chandak, Giriraj R. (JSS Academy of Higher Education and Research) ; Mercader, Josep M. (Harvard Medical School) ; Costanzo, Maria C. (Broad Institute of MIT and Harvard) ; Jang, Dongkeun (Broad Institute of MIT and Harvard) ; Burtt, Noël P. (Broad Institute of MIT and Harvard) ; Villalpando, Clicerio Gonzalez (InstitutoNacional de Salud Publica Y Centro de Estudios en Diabetes (Mèxic)) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Fornage, Myriam (University of Texas Health Science at Houston) ; Tai, EShyong (Yong Loo Lin School of Medicine) ; van Dam, Rob M. (Milken Institute School of Public Health) ; Lehtimäki, Terho (Finnish Cardiovascular Research Center - Tampere) ; Chaturvedi, Nish (MRC Unit for Lifelong Health and Ageing at UCL) ; Yokota, Mitsuhiro (Kurume University School of Medicine) ; Liu, Jianjun (Genome Institute of Singapore) ; Reilly, Dermot F. (Merck Sharp & Dohme Corp.. Genetics) ; McKnight, Amy Jayne (Queen's University of Belfast) ; Kee, Frank (Queen's University of Belfast) ; Jöckel, Karl-Heinz (University of Duisburg-Essen) ; McCarthy, Mark I. (University of Oxford) ; Palmer, Colin N. A. (University of Dundee) ; Vitart, Veronique (University of Edinburgh) ; Hayward, Caroline (University of Edinburgh) ; Simonsick, Eleanor (National Institute On Aging) ; van Duijn, Cornelia M. (University Medical Center Rotterdam) ; Jin, Zi-Bing (Wenzhou Medical University) ; Qu, Jia (Wenzhou Medical University) ; Hishigaki, Haretsugu (Tokushima Research Institute) ; Lin, Xu (University of Chinese Academy of Sciences) ; März, Winfried (Medical University of Graz) ; Gudnason, Vilmundur (University of Iceland) ; Tardif, Jean-Claude (Université de Montréal) ; Lettre, Guillaume (Université de Montréal) ; Hart, Leen M.'t (Amsterdam Public Health Research Institute) ; Elders, Petra J. M. (Amsterdam Public Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Kumari, Meena (University of Essex) ; Kivimaki, Mika (University College London) ; van der Harst, Pim (Utrecht University) ; Spector, Tim D. (King's College London) ; Loos, Ruth J. F. (Icahn School of Medicine at Mount Sinai) ; Province, Michael A. (Washington University School of Medicine) ; Parra, Esteban J. (University of Toronto at Mississauga) ; Cruz, Miguel (Centro Medico Nacional Siglo XXI) ; Psaty, Bruce M. (University of Washington) ; Brandslund, Ivan (University of Southern Denmark) ; Pramstaller, Peter P. (Affiliated Institute of the University of Lübeck) ; Rotimi, Charles N. (Center for Research On Genomics and Global Health) ; Christensen, Kaare (University of Southern Denmark) ; Ripatti, Samuli (Broad Institute of MIT and Harvard) ; Widén, Elisabeth (University of Helsinki) ; Hakonarson, Hakon (The University of Pennsylvania Perelman School of Medicine) ; Grant, Struan F. A. (Children's Hospital of Philadelphia (Pennsilvània)) ; Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ; de Graaf, Jacqueline (Radboud University Medical Center) ; Loeffler, Markus (University of Leipzig) ; Kronenberg, Florian (German Chronic Kidney Disease Study (Alemanya)) ; Gu, Dongfeng (Southern University of Science and Technology) ; Erdmann, Jeanette (University Heart Center Lübeck) ; Schunkert, Heribert (Partner Site Munich Heart Alliance) ; Franks, Paul W. (Lund University Diabetes Centre) ; Linneberg, Allan (University of Copenhagen) ; Jukema, J. Wouter (Netherlands Heart Institute) ; Khera, Amit V. (Verve Therapeutics) ; Männikkö, Minna (Northern Finland Birth Cohorts) ; Jarvelin, Marjo-Riitta (University of Oulu) ; Kutalik, Zoltan (Swiss Institute of Bioinformatics) ; Francesco, Cucca (University of Sassari) ; Mook-Kanamori, Dennis O. (Leiden University Medical Center) ; van Dijk, Ko Willems (Leiden University Medical Center) ; Watkins, Hugh (University of Oxford) ; Strachan, David P. (University of London) ; Grarup, Niels (University of Copenhagen) ; Sever, Peter (Imperial College London) ; Poulter, Neil (Imperial College London) ; Chuang, Lee-Ming (National Taiwan University Hospital (Taipei, Taiwan)) ; Rotter, Jerome I. (Lundquist Institute for Biomedical Innovations (Formerly LABioMed) at Harbor-UCLA Medical Center) ; Dantoft, Thomas M. (Bispebjerg and Frederiksberg Hospital) ; Karpe, Fredrik (NIHR Oxford Biomedical Research Centre) ; Neville, Matt J. (NIHR Oxford Biomedical Research Centre) ; Timpson, Nicholas J. (University of Bristol) ; Cheng, Ching-Yu (Duke-NUS Medical School) ; Wong, Tien-Yin (Duke-NUS Medical School) ; Khor, Chiea Chuen (Genome Institute of Singapore) ; Li, Hengtong (Singapore Eye Research Institute) ; Sabanayagam, Charumathi (Duke-NUS Medical School) ; Peters, Annette (German Center for Diabetes Research (DZD)) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Hattersley, Andrew T. (University of Exeter) ; Pedersen, Nancy L. (Karolinska Institutet (Estocolm, Suècia)) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia)) ; Boomsma, Dorret I. (Amsterdam Public Health Research Institute) ; Willemsen, Allegonda H. M. (Amsterdam Public Health Research Institute) ; Cupples, LAdrienne (US National Institutes of Health) ; van Meurs, Joyce B. J. (University Medical Center Rotterdam) ; Ghanbari, Mohsen (Mashhad University of Medical Sciences) ; Gordon-Larsen, Penny (University of North Carolina) ; Huang, Wei (Chinese National Human Genome Center at Shanghai) ; Kim, Young Jin (National Institute of Health) ; Tabara, Yasuharu (Kyoto University Graduate School of Medicine) ; Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine) ; Langenberg, Claudia (Berlin Institute of Health at Charité - Universitätsmedizin) ; Zeggini, Eleftheria (Helmholtz Zentrum München - German Research Center for Environmental Health) ; Kuusisto, Johanna (University of Eastern Finland and Kuopio University Hospital) ; Laakso, Markku (University of Eastern Finland and Kuopio University Hospital) ; Ingelsson, Erik (Stanford University) ; Abecasis, Goncalo (Regeneron Pharmaceuticals) ; Chambers, John C. (Imperial College London) ; Kooner, Jaspal S. (Imperial College London) ; de Vries, Paul S. (The University of Texas Health Science Center at Houston) ; Morrison, Alanna C. (The University of Texas Health Science Center at Houston) ; Hazelhurst, Scott (University of the Witwatersrand) ; Ramsay, Michèle (University of the Witwatersrand) ; North, Kari E. (University of North Carolina) ; Daviglus, Martha (University of Illinois College of Medicine) ; Kraft, Peter (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Whitfield, John B. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Abbas, Shahid (Faisalabad Institute of Cardiology) ; Saleheen, Danish (Columbia University Irving Medical Center) ; Walters, Robin G. (University of Oxford) ; Holmes, Michael V. (Oxford University Hospitals) ; Black, Corri (University of Aberdeen) ; Smith, Blair H. (University of Dundee) ; Baras, Aris (Regeneron Pharmaceuticals) ; Justice, Anne E. (Geisinger Health) ; Buring, Julie E. (Harvard Medical School) ; Ridker, Paul M. (Harvard Medical School) ; Chasman, Daniel I. (Harvard Medical School) ; Kooperberg, Charles (Fred Hutchinson Cancer Center) ; Tamiya, Gen (Tohoku University) ; Yamamoto, Masayuki (Tohoku University) ; van Heel, David A (Queen Mary University of London) ; Trembath, Richard C. (King's College London) ; Wei, Wei-Qi (Vanderbilt University Medical Center) ; Jarvik, Gail P. (University of Washington) ; Namjou, Bahram (Cincinnati Children's Hospital Medical Center) ; Hayes, M. Geoffrey (Northwestern University) ; Ritchie, Marylyn D. (University of Pennsylvania) ; Jousilahti, Pekka (Finnish Institute for Health and Welfare) ; Salomaa, Veikko (Finnish Institute for Health and Welfare) ; Hveem, Kristian (St Olav's University Hospital) ; Åsvold, Bjørn Olav (St Olav's University Hospital) ; Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences) ; Kamatani, Yoichiro (The University of Tokyo) ; Okada, Yukinori (The University of Tokyo) ; Murakami, Yoshinori (The University of Tokyo) ; Kim, Bong-Jo (National Institute of Health) ; Thorsteinsdottir, Unnur (University of Iceland) ; Stefansson, Kari (The University of Manchester) ; Zhang, Jifeng (University of Michigan) ; Chen, YEugene (University of Michigan) ; Ho, Yuk-Lam (VA Boston Healthcare System) ; Lynch, Julie A. (University of Massachusetts) ; Rader, Daniel J. (University of Pennsylvania) ; Tsao, Philip S. (Stanford University School of Medicine) ; Chang, Kyong-Mi (University of Pennsylvania Perelman School of Medicine) ; Cho, Kelly (Brigham Women's Hospital) ; O'Donnell, Christopher J. (Brigham Women's Hospital) ; Gaziano, John M. (Brigham Women's Hospital) ; Wilson, Peter W. F. (Emory University School of Medicine) ; Frayling, Timothy M. (University of Exeter Medical School) ; Hirschhorn, Joel N. (Harvard Medical School) ; Kathiresan, Sekar (Harvard Medical School) ; Mohlke, Karen L. (University of North Carolina) ; Sun, Yan V. (Atlanta VA Health Care System) ; Morris, Andrew P. (The University of Manchester) ; Boehnke, Michael (University of Michigan) ; Brown, Christopher D. (University of Pennsylvania) ; Natarajan, Pradeep (Massachusetts General Hospital) ; Deloukas, Panos (King Abdulaziz University) ; Willer, Cristen J. (University of Michigan) ; Assimes, Themistocles (Stanford University School of Medicine. Cardiovascular Institute) ; Peloso, Gina M (Boston University School of Public Health. Department of Biostatistics) ; Universitat Autònoma de Barcelona
Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hindering downstream translational efforts such as drug target discovery. [...]
2022 - 10.1186/s13059-022-02837-1
Genome biology, Vol. 23 (december 2022)  
7.
13 p, 1.9 MB Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome / Barry, Alexandra (Broad Institute of MIT and Harvard) ; McNulty, Michelle T. (Broad Institute of MIT and Harvard) ; Jia, Xiaoyuan (The University of Tokyo) ; Gupta, Yask (Columbia University College of Physicians and Surgeons) ; Debiec, Hanna (Institut National de la Santé et de la Recherde Médicale) ; Luo, Yang (Broad Institute of MIT and Harvard) ; Nagano, China (Kobe University Graduate School of Medicine) ; Horinouchi, Tomoko (Kobe University Graduate School of Medicine) ; Jung, Seulgi (University of Ulsan College of Medicine) ; Colucci, Manuela (Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Pediatrico Bambino Gesù) ; Ahram, Dina F. (Columbia University College of Physicians and Surgeons) ; Mitrotti, Adele (University of Bari Aldo Moro) ; Sinha, Aditi (AIIMS) ; Teeninga, Nynke (Radboud University Medical Center) ; Jin, Gina (Columbia University College of Physicians and Surgeons) ; Shril, Shirlee (Harvard Medical School) ; Caridi, Gianluca (IRCCS Instituto Giannina Gaslini) ; Bodria, Monica (IRCCS Instituto Giannina Gaslini) ; Lim, Tze Y. (Columbia University College of Physicians and Surgeons) ; Westland, Rik (Amsterdam UMC. University Medical Center) ; Zanoni, Francesca (University of Pennsylvania) ; Marasa, Maddalena (Columbia University College of Physicians and Surgeons) ; Turudic, Daniel (University of Zagreb Medical School) ; Giordano, Mario (Bari Polyclinic Giovanni XXIII Children's Hospital) ; Gesualdo, Loreto (University of Bari Aldo Moro) ; Magistroni, Riccardo (University of Modena and Reggio Emilia) ; Pisani, Isabella (Università di Parma) ; Fiaccadori, Enrico (Università di Parma) ; Reiterova, Jana (Charles University) ; Maringhini, Silvio (ISMETT) ; Morello, William (Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico) ; Montini, Giovanni (University of Milan) ; Weng, Patricia L. (UCLA Medical Center and UCLA Medical Center-Santa Monica) ; Scolari, Francesco (University of Brescia and ASST Spedali Civili of Brescia) ; Saraga, Marijan (University of Split) ; Tasic, Velibor (University Children's Hospital Macedonia) ; Santoro, Domenica (University of Messina) ; van Wijk, Joanna A. E. (Amsterdam UMC. University Medical Center) ; Milošević, Danko (Croatian Academy of Medical Sciences) ; Kawai, Yosuke (The University of Tokyo) ; Kiryluk, Krzysztof (Columbia University College of Physicians and Surgeons) ; Pollak, Martin R. (Columbia University Irving Medical Center New York-Presbyterian Morgan Stanley Children's Hospital in New York) ; Gharavi, Ali (Columbia University College of Physicians and Surgeons) ; Lin, Fangmin (Columbia University Irving Medical Center New York-Presbyterian Morgan Stanley Children's Hospital in New York) ; Simœs e Silva, Ana Cristina (Federal University of Minas Gerais) ; Loos, Ruth J. F. (Icahn School of Medicine at Mount Sinai) ; Kenny, Eimear E. (Icahn School of Medicine at Mount Sinai) ; Schreuder, Michiel F. (Radboud University Medical Center) ; Zurowska, Aleksandra (Medical University Gdansk.) ; Dossier, Claire (Hôpital Robert-Debré) ; Ariceta Iraola, Gema (Hospital Universitari Vall d'Hebron) ; Drozynska-Duklas, Magdalena (Medical University Gdansk) ; Hogan, Julien (Hôpital Robert-Debré) ; Jankauskiene, Augustina (Vilnius University) ; Hildebrandt, Friedhelm (Harvard Medical School) ; Prikhodina, Larisa (Pirogov Russian National Research Medical University) ; Song, Kyuyoung (University of Ulsan College of Medicine) ; Bagga, Arvind (AIIMS) ; Cheong, Hae (Hallym University Sacred Heart Hospital) ; Ghiggeri, Gian Marco (IRCCS Instituto Giannina Gaslini) ; Vachvanichsanong, Prayong (Prince of Songkla University) ; Nozu, Kandai (Kobe University Graduate School of Medicine) ; Lee, Dongwon (Harvard Medical School) ; Vivarelli, Marina (Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Pediatrico Bambino Gesù) ; Raychaudhuri, Soumya (University of Manchester) ; Tokunaga, Katsushi (The University of Tokyo) ; Sanna-Cherchi, Simone (Columbia University College of Physicians and Surgeons) ; Ronco, Pierre (Centre Hospitalier du Mans) ; Iijima, Kazumoto (Kobe University Graduate School of Medicine) ; Sampson, Matthew G. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Universitat Autònoma de Barcelona
Pediatric steroid-sensitive nephrotic syndrome (pSSNS) is the most common childhood glomerular disease. Previous genome-wide association studies (GWAS) identified a risk locus in the HLA Class II region and three additional independent risk loci. [...]
2023 - 10.1038/s41467-023-37985-w
Nature communications, Vol. 14 (april 2023)  
8.
8 p, 3.2 MB Reversible Electrical Control of Interfacial Charge Flow across van der Waals Interfaces / Fu, Shuai (Max Planck Institute for Polymer Research (Germany)) ; Jia, Xiaoyu (Max Planck Institute for Polymer Research (Germany)) ; Hassan, Aliaa S. (Max Planck Institute for Polymer Research (Germany)) ; Zhang, Heng (Max Planck Institute for Polymer Research (Germany)) ; Zheng, Wenhao (Max Planck Institute for Polymer Research (Germany)) ; Gao, Lei (Max Planck Institute for Polymer Research (Germany)) ; Di Virgilio, Lucia (Max Planck Institute for Polymer Research (Germany)) ; Krasel, Sven (Max Planck Institute for Polymer Research (Germany)) ; Beljonne, David (Université de Mons) ; Tielrooij, Klaas-Jan (Institut Català de Nanociència i Nanotecnologia) ; Bonn, Mischa (Max Planck Institute for Polymer Research (Germany)) ; Wang, Hai I. (Max Planck Institute for Polymer Research (Germany))
Bond-free integration of two-dimensional (2D) materials yields van der Waals (vdW) heterostructures with exotic optical and electronic properties. Manipulating the splitting and recombination of photogenerated electron-hole pairs across the vdW interface is essential for optoelectronic applications. [...]
2023 - 10.1021/acs.nanolett.2c04795
Nano letters, Vol. 23, Issue 5 (March 2023) , p. 1850-1857  
9.
32 p, 13.6 MB The Arabidopsis SAC9 enzyme is enriched in a cortical population of early endosomes and restricts PI(4,5)P2 at the plasma membrane / Lebecq, Alexis (Université de Lyon) ; Doumane, Mehdi (Université de Lyon) ; Fangain, Aurelie (Université de Lyon) ; Bayle, Vincent (Université de Lyon) ; Leong, Jia Xuan (University of Tübingen) ; Rozier, Frédérique (Université de Lyon) ; Marques-Bueno, Mar (Centre de Recerca en Agrigenòmica) ; Armengot, Laia (Centre de Recerca en Agrigenòmica) ; Boisseau, Romain (University of Montana. Division of Biological Science) ; Simon, Mathilde Laetitia (Université de Lyon) ; Franz-Wachtel, Mirita (University of Tübingen. Department of Quantitative Proteomics) ; Macek, Boris (University of Tübingen. Department of Quantitative Proteomics) ; Üstün, Suayib (Ruhr-University Bochum) ; Jaillais, Yvon (Université de Lyon) ; Caillaud, Marie-Cécile (Université de Lyon)
Membrane lipids, and especially phosphoinositides, are differentially enriched within the eukaryotic endomembrane system. This generates a landmark code by modulating the proper-ties of each membrane. [...]
2022 - 10.7554/eLife.73837
eLife, Vol. 11 (August 2022) , art. e73837  
10.
9 p, 1.5 MB Correlations between experiments and simulations for formic acid oxidation / Bagger, Alexander (University of Copenhagen. Department of Chemistry) ; Jensen, Kim D. (University of Copenhagen. Department of Chemistry) ; Rashedi, Maryam (University of Tehran. College of Science) ; Luo, Rui (Nanjing University of Science & Technology. School of Environmental and Biological Engineering) ; Du, Jia (University of Bern. Department of Chemistry, Biochemistry and Pharmaceutical Sciences) ; Zhang, Damin (University of Bern. Department of Chemistry, Biochemistry and Pharmaceutical Sciences) ; Pereira, Inês J. (University of Copenhagen. Department of Chemistry) ; Escudero-Escribano, María (Institut Català de Nanociència i Nanotecnologia) ; Arenz, Matthias (University of Bern. Department of Chemistry, Biochemistry and Pharmaceutical Sciences) ; Rossmeisl, Jan (University of Copenhagen. Department of Chemistry)
Electrocatalytic conversion of formic acid oxidation to CO2 and the related CO2 reduction to formic acid represent a potential closed carbon-loop based on renewable energy. However, formic acid fuel cells are inhibited by the formation of site-blocking species during the formic acid oxidation reaction. [...]
2022 - 10.1039/d2sc05160e
Chemical science, Vol. 13, Issue 45 (December 2022) , p. 13409-13417  

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