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11 p, 771.0 KB |
Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?
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Cabrera Serrano, Antonio José (Instituto de Investigación Sanitaria de Granada) ;
Sánchez Maldonado, José Manuel (Instituto de Investigación Sanitaria de Granada) ;
ter Horst, Rob (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) ;
Macauda, Angelica (German Cancer Research Center) ;
García Martín, Paloma (Hospital Campus de la Salud (Granada)) ;
Benavente, Yolanda (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Landi, Stefano (Department of Biology. University of Pisa) ;
Clay-Gilmour, Alyssa (Department of Epidemiology & Biostatistics. Arnold School of Public Health. University of South Carolina) ;
Niazi, Yasmeen (Hopp Children's Cancer Center) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez-Sevilla, Juan Jose (Department of Leukemia. The University of Texas MD Anderson Cancer Center) ;
Pérez, Eva María (Hospital Campus de la Salud) ;
Maffei, Rossana (University of Modena and Reggio Emilia) ;
Blanco, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giaccherini, Matteo (Department of Biology. University of Pisa) ;
Cerhan, James R. (Department of Quantitative Health Sciences. Mayo Clinic) ;
Marasca, Roberto (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia. AOU Policlinico) ;
Lopez Nevot, Miguel Angel (Hospital Universitario Virgen de las Nieves (Granada)) ;
Chen-Liang, Tzu Hua (Hospital Universitario Morales Meseguer (Múrcia)) ;
Thomsen, Hauke (MSB Medical School Berlin) ;
Gámez, Irene (Hematology Department. Morales Meseguer University Hospital) ;
Campa, Daniele (Department of Biology. University of Pisa) ;
Moreno Aguado, Víctor (Facultat de Medicina. Universitat de Barcelona) ;
de Sanjosé, Silvia (Universitat de Barcelona) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Álvarez, María Flor (Instituto de Investigación Biomédica de Salamanca) ;
Dierssen-Sotos, Trinidad (Universidad de Cantabria) ;
Jerez, Andrés (Vall d'Hebron Institut d'Oncologia) ;
Butrym, Aleksandra (Department of Cancer Prevention and Therapy. Medical University of Wrocław) ;
Norman, Aaron D. (Department of Quantitative Health Sciences. Mayo Clinic) ;
Luppi, Mario (University of Modena and Reggio Emilia) ;
Slager, Susan L. (Mayo Clinic) ;
Hemminki, Kari (Charles University in Prague) ;
Li, Yang (Hannover Medical School) ;
Berndt, Sonja I. (National Institutes of Health (Estats Units d'Amèrica)) ;
Casabonne, Delphine (Universitat de Barcelona) ;
Alcoceba, Miguel (Instituto de Investigación Biomédica de Salamanca) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Netea, Mihai G. (Department for Immunology & Metabolism. University of Bonn) ;
Försti, Asta (Hopp Children's Cancer Center) ;
Canzian, Federico (German Cancer Research Center) ;
Sainz, Juan (Department of Biochemistry and Molecular Biology. Universidad de Granada)
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults worldwide. Although genome-wide association studies (GWAS) have uncovered the germline genetic component underlying CLL susceptibility, the potential use of GWAS-identified risk variants to predict disease progression and patient survival remains unexplored. [...]
2023 -  10.3390/ijms24098005
International journal of molecular sciences, Vol. 24 Núm. 9 (may 2023) , p. 8005
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15 p, 2.3 MB |
Induction of Innate Memory in Human Monocytes Exposed to Mixtures of Bacterial Agents and Nanoparticles
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Della Camera, Giacomo (European Commission. Joint Research Centre) ;
Liu, Tinghao (China-Italy Joint Laboratory of Pharmacobiotechnology for Medical Immunomodulation) ;
Yang, Wenjie (China-Italy Joint Laboratory of Pharmacobiotechnology for Medical Immunomodulation) ;
Li, Yang (China-Italy Joint Laboratory of Pharmacobiotechnology for Medical Immunomodulation) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Gioria, Sabrina (European Commission. Joint Research Centre) ;
Italiani, Paola (China-Italy Joint Laboratory of Pharmacobiotechnology for Medical Immunomodulation) ;
Boraschi, Diana (China-Italy Joint Laboratory of Pharmacobiotechnology for Medical Immunomodulation)
We assessed whether concomitant exposure of human monocytes to bacterial agents and different engineered nanoparticles can affect the induction of protective innate memory, an immune mechanism that affords better resistance to diverse threatening challenges. [...]
2022 - 10.3390/ijms232314655
International journal of molecular sciences, Vol. 23, Issue 23 (November 2022) , art. 14655
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6 p, 1.5 MB |
Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia : a CRuCIAL study
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García Martín, Paloma (Hospital Campus de la Salud (Granada)) ;
Moñiz Díez, Ana (Instituto de Investigación Sanitaria de Granada) ;
Sánchez Maldonado, José Manuel (Instituto de Investigación Sanitaria de Granada) ;
Cabrera Serrano, Antonio José (Instituto de Investigación Sanitaria de Granada) ;
ter Horst, Rob (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) ;
Benavente, Yolanda (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Landi, Stefano (Department of Biology. University of Pisa) ;
Macauda, Angelica (German Cancer Research Center) ;
Clay-Gilmour, Alyssa (University of South Carolina) ;
Hernández-Mohedo, Francisca (Instituto de Investigación Sanitaria de Granada) ;
Niazi, Yasmeen (Hopp Children's Cancer Center) ;
González-Sierra, Pedro Antonio (Instituto de Investigación Sanitaria de Granada) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez-Sevilla, Juan Jose (Hospital del Mar (Barcelona, Catalunya)) ;
Maffei, Rossana (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia) ;
Blanco, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giaccherini, Matteo (Department of Biology. University of Pisa) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cerhan, James (Mayo Clinic) ;
Marasca, Roberto (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia) ;
Cañadas-Garre, Marisa (Instituto de Investigación Sanitaria de Granada) ;
Lopez Nevot, Miguel Angel (Hospital Universitario Virgen de las Nieves (Granada)) ;
Chen-Liang, Tzu (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Thomsen, Hauke (ProtaGene CGT GmbH (Alemanya)) ;
Gámez, Irene (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Morros, Rosa (Institut d'Investigació Biomèdica de Bellvitge) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Álvarez, María (Hospital Universitario de Salamanca) ;
Llorca, Javier (Universidad de Cantabria) ;
Jerez, Andrés (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Berndt, Sonja (National Institutes of Health (Estats Units d'Amèrica)) ;
Butrym, Aleksandra (Medical University of Wrocław) ;
Norman, Aaron D. (Mayo Clinic) ;
Casabonne, Delphine (CCIBER Epidemiología y Salud Pública (Madrid)) ;
Luppi, Mario (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia) ;
Slager, Susan L. (Mayo Clinic) ;
Hemminki, Kari (Charles University in Prague) ;
Li, Yang (CHannover Medical School) ;
Alcoceba, Miguel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Campa, Daniele (Department of Biology. University of Pisa) ;
Canzian, Federico (German Cancer Research Center (Alemanya)) ;
De Sanjose, Silvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Försti, Asta (Hopp Children's Cancer Center) ;
Netea, Mihai G. (University of Bonn) ;
Jurado, Manuel (Instituto de Investigación Sanitaria de Granada) ;
Sainz, Juan (Universidad de Granada. Departamento de Bioquímica y Biología Molecular) ;
Universitat Autònoma de Barcelona
2022 - 10.1038/s41408-022-00676-8
Blood Cancer Journal, Vol. 12 Núm. 5 (may 2022) , p. 79
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20 p, 3.7 MB |
Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation
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Li, Yang (Hebei Normal University) ;
Shi, Zhenzhen (Kansas State University. Department of Anatomy and Physiology) ;
Radauer-Preiml, Isabella (University of Salzburg. Department of Molecular Biology) ;
Andosch, Ancuela (University of Salzburg. Department of Molecular Biology) ;
Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Luetz-Meindl, Ursula (University of Salzburg. Department of Molecular Biology) ;
Cobaleda-Siles, Macarena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lin, Zhoumeng (Kansas State University. Department of Anatomy and Physiology) ;
Jaberi-Douraki, Majid (Kansas State University. Department of Anatomy and Physiology) ;
Italiani, Paola (National Research Council) ;
Horejs-Hoeck, Jutta (University of Salzburg. Department of Molecular Biology) ;
Himly, Martin (University of Salzburg. Department of Molecular Biology) ;
Monteiro-Riviere, Nancy A. (Kansas State University. Department of Anatomy and Physiology) ;
Duschl, Albert (University of Salzburg. Department of Molecular Biology) ;
Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ;
Boraschi, Diana (National Research Council)
Nanoparticles (NPs) are easily contaminated by bacterial endotoxin (lipopolysaccharide [LPS]). The presence of LPS can be responsible for many immune/inflammatory effects attributed to NPs. In this study, we examined the effects of LPS adsorption on the NP surface on the formation of a biocorona in biological fluids and on the subsequent inflammation-inducing activity of NPs. [...]
2017 - 10.1080/17435390.2017.1401142
Nanotoxicology, Vol. 11, Issue 9-10 (December 2017) , p. 1157-1175
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6 p, 1.1 MB |
Analysis on the filament structure evolution in reset transition of Cu/HfO₂/Pt RRAM device
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Zhang, Meiyun (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Long, Shibing (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Li, Yang (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Liu, Qi (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Lv, Hangbing (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Miranda, Enrique (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Suñé, Jordi, 1963- (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Liu, Ming (Chinese Academy of Sciences. Institute of Microelectronics (Beijing))
The resistive switching (RS) process of resistive random access memory (RRAM) is dynamically correlated with the evolution process of conductive path or conductive filament (CF) during its breakdown (rupture) and recovery (reformation). [...]
2016 - 10.1186/s11671-016-1484-8
Nanoscale Research Letters, Vol. 11 (May 2016) , art. 269
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30 p, 3.6 MB |
Conductance quantization in resistive random access memory
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Li, Yang (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Long, Shibing (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Liu, Yang (University of Science and Technology Beijing. Department of Materials Physics and Chemistry) ;
Hu, Chen (University of Science and Technology Beijing. Department of Materials Physics and Chemistry) ;
Teng, Jiao (University of Science and Technology Beijing. Department of Materials Physics and Chemistry) ;
Liu, Qi (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Lv, Hangbing (Chinese Academy of Sciences. Institute of Microelectronics (Beijing)) ;
Suñé, Jordi 1963- (Universitat Autònoma de Barcelona. Departament d'Enginyeria Electrònica) ;
Liu, Ming (Chinese Academy of Sciences. Institute of Microelectronics (Beijing))
The intrinsic scaling-down ability, simple metal-insulator-metal (MIM) sandwich structure, excellent performances, and complementary metal-oxide-semiconductor (CMOS) technology-compatible fabrication processes make resistive random access memory (RRAM) one of the most promising candidates for the next-generation memory. [...]
2015 - 10.1186/s11671-015-1118-6
Nanoscale Research Letters, Vol. 10 (December 2015) , art. 420
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7 p, 1.2 MB |
designGG : an R-package and web tool for the optimal design of genetical genomics experiments
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Li, Yang (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ;
Swertz, Morris A. (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ;
Vera Rodríguez, Gonzalo (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ;
Fu, Jingyuan (University of Groningen. Department of Genetics (Groningen, Països Baixos)) ;
Breitling, Rainer (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos)) ;
Jansen, Ritsert C. (University of Groningen. Groningen Biomolecular Sciences and Biotechnology Institute (Haren, Països Baixos))
Background: High-dimensional biomolecular profiling of genetically different individuals in one or more environmental conditions is an increasingly popular strategy for exploring the functioning of complex biological systems. [...]
2009 - 10.1186/1471-2105-10-188
BMC bioinformatics, Vol. 10, N. 188 (June 2009) , p. 1-7
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