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Depósito Digital de Documentos de la UAB Encontrados 3 registros  La búsqueda tardó 0.00 segundos. 
1.
37 p, 20.5 MB Epigenetic regulation during cancer transitions across 11 tumour types / Terekhanova, Nadezhda V. (Washington University in St Louis) ; Karpova, Alla (Washington University in St Louis) ; Liang, Wen Wei (Washington University in St Louis) ; Strzalkowski, Alexander (Department of Computer Science. Princeton University) ; Chen, Siqi (Washington University in St Louis) ; Li, Yize (Washington University in St Louis) ; Southard-Smith, Austin N. (Washington University in St Louis) ; Iglesia, Michael D. (Washington University in St Louis) ; Wendl, Michael C. (Washington University in St Louis) ; Jayasinghe, Reyka G. (Washington University in St Louis) ; Liu, Jingxian (Washington University in St Louis) ; Song, Yizhe (Washington University in St Louis) ; Cao, Song (Washington University in St Louis) ; Houston, Andrew (Washington University in St Louis) ; Liu, Xiuting (Department of Medicine. Washington University in St Louis) ; Wyczalkowski, Michael A. (Washington University in St Louis) ; Lu, Rita Jui-Hsien (Washington University in St Louis) ; Caravan, Wagma (Washington University in St Louis) ; Shinkle, Andrew (Department of Medicine. Washington University in St Louis) ; Naser Al Deen, Nataly (Washington University in St Louis) ; Herndon, John M. (Washington University in St Louis) ; Mudd, Jacqueline (Department of Surgery. Washington University in St Louis) ; Ma, Cong (Department of Computer Science. Princeton University) ; Sarkar, Hirak (Department of Computer Science. Princeton University) ; Sato, Kazuhito (Washington University in St Louis) ; Ibrahim, Omar.M. (Washington University in St Louis) ; Mo, Chia-Kuei (Washington University in St Louis) ; Chasnoff, Sara E. (Washington University in St Louis) ; Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Held, Jasson M. (Washington University in St Louis) ; Pachynski, Russell (Washington University in St Louis) ; Schwarz, Julie K. (Department of Radiation Oncology. Washington University in St Louis) ; Gillanders, William E. (Washington University in St Louis) ; Kim, Albert H. (Department of Neurological Surgery. Washington University in St Louis) ; Vij, Ravi (Washington University in St Louis) ; DiPersio, John.F. (Washington University in St Louis) ; Puram, Sidharth V. (Department of Otolaryngology-Head & Neck Surgery. Washington University in St Louis) ; Chheda, Milan G. (Washington University in St Louis) ; Fuh, Katherine C. (Department of Obstetrics and Gynecology. Washington University in St Louis) ; DeNardo, David G. (Washington University in St Louis) ; Fields, Ryan C. (Washington University in St Louis) ; Chen, Feng (Washington University in St Louis) ; Raphael, Benjamin J. (Department of Computer Science. Princeton University) ; Ding, Li (Department of Genetics. Washington University in St Louis)
Chromatin accessibility is essential in regulating gene expression and cellular identity, and alterations in accessibility have been implicated in driving cancer initiation, progression and metastasis. [...]
2023 - 10.1038/s41586-023-06682-5
Nature, Vol. 623 Núm. 7986 (september 2023) , p. 432-441  
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2.
27 p, 8.1 MB Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin / Liang, Wen-Wei (Washington University in St. Louis) ; Lu, Rita Jui-Hsien Lu (Washington University in St. Louis) ; Jayasinghe, Reyka G. (Washington University in St. Louis) ; Foltz, Steven M. (Washington University in St. Louis) ; Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Geffen, Yifat (Massachusetts General Hospital) ; Wendl, Michael C. (Department of Mathematics. Washington University in St. Louis) ; Lazcano, Rossana (Departments of Pathology & Genomic Medicine. The University of Texas MD Anderson Cancer Center) ; Kolodziejczak, Iga (Medical University of Warsaw) ; Song, Yizhe (Washington University in St. Louis) ; Govindan, Akshay (Washington University in St. Louis) ; Demicco, Elisabeth G. (University of Toronto) ; Li, Xiang (Washington University in St. Louis) ; Li, Yize (Washington University in St. Louis) ; Sethuraman, Sunantha (Washington University in St. Louis) ; Payne, Samuel H. (Department of Biology. Brigham Young University) ; Fenyö, David (Department of Biochemistry and Molecular Pharmacology. NYU Grossman School of Medicine) ; Rodriguez, Henry (Office of Cancer Clinical Proteomics Research. National Cancer Institute) ; Wiznerowicz, Maciej (Poznań University of Medical Sciences) ; Shen, Hui (Van Andel Research Institute) ; Mani, D.R. (Broad Institute of Massachusetts Institute of Technology and Harvard) ; Rodland, Karin D. (Developmental. and Cancer Biology. Oregon Health & Science University) ; Lazar, Alexander J. (Departments of Pathology & Genomic Medicine. The University of Texas MD Anderson Cancer Center) ; Robles, Ana I. (Office of Cancer Clinical Proteomics Research) ; Ding, Li (Washington University in St. Louis) ; Universitat Autònoma de Barcelona
DNA methylation plays a critical role in establishing and maintaining cellular identity. However, it is frequently dysregulated during tumor development and is closely intertwined with other genetic alterations. [...]
2023 - 10.1016/j.ccell.2023.07.013
Cancer Cell, Vol. 41 Núm. 9 (november 2023) , p. 1567-1585.e7  
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3.
27 p, 2.4 MB Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples / Bailey, Matthew H. (Washington University School of Medicine. Department of Medicine (USA)) ; Meyerson, William U. (Yale University. Program in Computational Biology and Bioinformatics (USA)) ; Dursi, Lewis Jonathan (Ontario Institute for Cancer Research. Computational Biology Program (Canada)) ; Wang, Liang-Bo (Washington University School of Medicine. Department of Medicine (USA)) ; Dong, Guanlan (Washington University School of Medicine. Department of Medicine (USA)) ; Liang, Wen-Wei (Washington University School of Medicine. Department of Medicine(USA)) ; Weerasinghe, Amila (Washington University School of Medicine. Department of Medicine (USA)) ; Li, Shantao (Yale University. Program in Computational Biology and Bioinformatics (USA)) ; Kelso, Sean (Washington University School of Medicine. Department of Medicine (USA)) ; Saksena, Gordon (Broad Institute of MIT and Harvard) ; Ellrott, Kyle (Oregon Health and Science University. Biomedical Engineering (USA)) ; Wendl, Michael C. (Washington University School of Medicine. Department of Genetics (USA)) ; Wheeler, David A. (Baylor College of Medicine. Department of Molecular and Human Genetics (USA)) ; Getz, Gad (Broad Institute of MIT and Harvard) ; Simpson, Jared T. (Ontario Institute for Cancer Research. Computational Biology Program (Canada)) ; Gerstein, Mark B. (Yale University. Program in Computational Biology and Bioinformatics (USA)) ; Ding, Li (Washington University School of Medicine. Department of Medicine (USA))
The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. [...]
2020 - 10.1038/s41467-020-18151-y
Nature communications, Vol. 11 (September 2020) , art. 4748
2 documentos
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