Lupu, Ruth - Resultados de la búsqueda - Depósito Digital de Documentos de la UAB

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27 p, 2.8 MB

Tumor Cell-Intrinsic Immunometabolism and Precision Nutrition in Cancer Immunotherapy / Cuyàs, Elisabet (Institut d'Investigació Biomèdica de Girona) ; Verdura, Sara (Institut d'Investigació Biomèdica de Girona) ; Martin-Castillo, Begoña (Institut Català d'Oncologia) ; Alarcón Cor, Tomás (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Lupu, Ruth (Mayo Clinic Cancer Center) ; Bosch-Barrera, J (Universitat de Girona. Departament de Ciències Mèdiques) ; Menendez, Javier A. (Institut d'Investigació Biomèdica de Girona)
One of the greatest challenges in the cancer immunotherapy field is the need to biologically rationalize and broaden the clinical utility of immune checkpoint inhibitors (ICIs). The balance between metabolism and immune response has critical implications for overcoming the major weaknesses of ICIs, including their lack of universality and durability. [...]
2020 - DOI (Digital Object Identifier)

10.3390/cancers12071757
Cancers, Vol. 12, Issue 7 (July 2020) , art. 1757

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18 p, 8.3 MB

Suppression of endogenous lipogenesis induces reversion of the malignant phenotype and normalized differentiation in breast cancer / Gonzalez-Guerrico, Anatilde M. (Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, MN, USA) ; Espinoza, Ingrid (Department of Biochemistry, University of Mississippi Medical Center, Jackson, MS, USA) ; Schroeder, Barbara (Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, MN, USA) ; Park, Cheol Hong (Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, MN, USA) ; Chandra Mohan, KVP (Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, MN, USA) ; Khurana, Ashwani (Department of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, MN, USA) ; Corominas-Faja, Bruna (Institut d'Investigació Biomèdica de Girona) ; Cuyàs, Elisabet (Institut d'Investigació Biomèdica de Girona) ; Alarcón Cor, Tomás (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Kleer, Celina (Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA) ; Menendez, Javier A. (Institut d'Investigació Biomèdica de Girona) ; Lupu, Ruth (Mayo Clinic Cancer Center, Rochester, MN, USA)
The correction of specific signaling defects can reverse the oncogenic phenotype of tumor cells by acting in a dominant manner over the cancer genome. Unfortunately, there have been very few successful attempts at identifying the primary cues that could redirect malignant tissues to a normal phenotype. [...]
2016 - DOI (Digital Object Identifier)

10.18632/oncotarget.9463
Oncotarget, Vol. 7 (may 2016) , p. 71151-71168

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