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12 p, 2.4 MB Biomarkers and polymorphisms in pancreatic neuroendocrine tumors treated with sunitinib / Jiménez-Fonseca, Paula (Medical Oncology Department, Hospital Universitario Central de Asturias) ; Martín, Miguel Navarro (Medical Oncology Department, Hospital Universitario de Salamanca, IBSAL) ; Carmona-Bayonas, Alberto (Hematology and Medical Oncology Department, Hospital Universitario Morales Meseguer, UMU, IMIB) ; Calvo, Alfonso (Clínica Universidad de Navarra. Centro de Investigación Médica Aplicada) ; Fernández-Mateos, Javier (Molecular Medicine Unit, IBSAL, Department of Medicine, University of Salamanca) ; Redrado, Miriam (IDISNA and Program in Solid Tumors and Biomarkers, Center for Applied Medical Research (CIMA), Department of Histology and Pathology, University of Navarra, Pamplona) ; Capdevila Castillon, Jaume (Hospital Universitari Vall d'Hebron) ; Lago, Nieves Martínez (Medical Oncology Department, Hospital Universitario de A Coruña) ; Lacasta, Adelaida (Medical Oncology Department, Hospital Universitario Donostia) ; Muñarriz, Javier (Medical Oncology Department, Hospital General Universitario de Castellón) ; Segura, Ángel (Medical Oncology Department, Hospital Universitario La Fe) ; Fuster, Josep (Medical Oncology Department, Hospital Universitario Son Espases) ; Barón, Francisco (Medical Oncology Department, Hospital Universitario de Santiago de Compostela) ; Llanos, Marta (Medical Oncology Department, Hospital Universitario de Canarias) ; Serrano, Raquel (Medical Oncology Department, Hospital Universitario Reina Sofia, Cordoba, Spain) ; Castillo, Alfredo (Medical Oncology Department, Hospital Universitario Central de Asturias, Oviedo, Spain) ; Cruz Hernández, Juan Jesús (Medical Oncology Department, Hospital Universitario de Salamanca, IBSAL, Salamanca, Spain) ; Grande, Enrique (Medical Oncology Department, MD Anderson Cancer Center) ; Universitat Autònoma de Barcelona
Several circulating biomarkers and single nucleotide polymorphisms (SNPs) have been correlated with efficacy and tolerability to antiangiogenic agents. These associations remain unexplored in well-differentiated, metastatic pancreatic neuroendocrine tumors treated with the multitargeted tyrosine kinase inhibitor sunitinib. [...]
2018 - 10.18632/oncotarget.26380
Oncotarget, Vol. 9 (december 2018) , p. 36894-36905  

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