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1.
10 p, 736.9 KB Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage : a systematic review and meta-analysis of individual patient data / Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences. University of Edinburgh) ; Frantzias, Joseph (King's College Hospital NHS Foundation Trust) ; Lee, Robert J. (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK) ; Lyden, Patrick D. (Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA) ; Battey, Thomas W. K. (Massachusetts General Hospital (Boston)) ; Ayres, Alison M. (Massachusetts General Hospital (Boston)) ; Goldstein, Joshua N. (Massachusetts General Hospital (Boston)) ; Mayer, Stephan A. (Department of Neurology, Henry Ford Health System, Detroit, MI, USA) ; Steiner, Thorsten (Heidelberg University Hospital (Alemanya)) ; Wang, Xia (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ; Arima, Hisatomi (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ; Hasegawa, Hitoshi (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Oishi, Makoto (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Godoy, Daniel A. (Intensive Care Unit, Hospital Interzonal de Agudos "San Juan Bautista", Catamarca, Argentina) ; Masotti, Luca (Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy) ; Dowlatshahi, Dar (Department of Medicine (Neurology), University of Ottawa and Ottawa Hospital Research Institute, Ottawa, ON, Canada) ; Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jang, Dong-Kyu (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ; Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castillo, José (Complejo Hospitalario Universitario de Santiago de Compostela) ; Yao, Xiaoying (Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China) ; Claassen, Jan (Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ; Volbers, Bastian (Bern University Hospital) ; Kazui, Seiji (Kazui Medical Office, Ikeda, Osaka, Japan) ; Okada, Yasushi (Department of Cerebrovascular Medicine and Neurology, National Hospital Organisation Kyushu Medical Centre, Fukuoka, Japan) ; Fujimoto, Shigeru (Division of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan) ; Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Li, Qi (Department of Neurology, ThE First Affiliated Hospital of Chongqing Medical University, Chongqing, China) ; Khoury, Jane (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Álvarez Sabín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández-Guillamon, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ; Cai, Chunyan (Centre for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA) ; Kate, Mahesh P. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; McCourt, Rebecca (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; Venkatasubramanian, Chitra (Division of Stroke and Neurocritical Care, Stanford University, Palo Alto, CA, USA) ; Diringer, Michael N. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ; Ikeda, Yukio (Department of Neurosurgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan) ; Worthmann, Hans (Department of Neurology, Hannover Medical School, Hannover, Germany) ; Ziai, Wendy C. (Johns Hopkins University School of Medicine, Department of Neurology, Anaesthesia and Critical Care Medicine, Division of Neurocritical Care, Baltimore, MD, USA) ; d'Esterre, Christopher D. (Department of Radiology, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada) ; Aviv, Richard I (Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada) ; Raab, Peter (Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany) ; Murai, Yasuo (Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan) ; Zazulia, Allyson R. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ; Butcher, Kenneth S. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; Seyedsaadat, Seyed Mohammad (Department of Radiology, Mayo Clinic, Rochester, MN, USA) ; Grotta, James C. (Memorial Hermann Hospital (Houston, Estats Units d'Amèrica)) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Broderick, Joseph P (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ; Yamamoto, Haruko (Center for Advanced Clinical and Translational Sciences, National Cerebral and Cerebrovascular Center, Suita, Osaka, Japan) ; Staykov, Dimitre (Department of Neurology, Hospital of the Brothers of St John, Eisenstadt, Austria) ; Connolly, E. Sander (Department of Neurosurgery, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ; Selim, Magdy (Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ; Leira, Rogelio (Complejo Hospitalario Universitario de Santiago de Compostela) ; Moon, Byung Hoo (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ; Demchuk, Andrew (Department of Clinical Neurosciences and Department of Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada) ; Di Napoli, Mario (Neurological Service, San Camillo de'Lellis General Hospital, Rieti, Italy) ; Fujii, Yukihiko (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Anderson, Craig S.. (The George Institute for Global Health, China at Peking University Health Science Center, Beijing, China) ; Rosand, Jonathan (Massachusetts General Hospital (Boston)) ; Universitat Autònoma de Barcelona
Intracerebral haemorrhage growth is associated with poor clinical outcome and is a therapeutic target for improving outcome. We aimed to determine the absolute risk and predictors of intracerebral haemorrhage growth, develop and validate prediction models, and evaluate the added value of CT angiography. [...]
2018 - 10.1016/S1474-4422(18)30253-9
The Lancet neurology, Vol. 17 (october 2018) , p. 885-894  
2.
13 p, 818.2 KB Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack : a pooled analysis of individual patient data from cohort studies / Wilson, Duncan (New Zealand Brain Research Institute, Christchurch, New Zealand) ; Ambler, Gareth (Department of Statistical Science, University College London, London, UK) ; Lee, Keon-Joo (Department of Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, South Korea) ; Lim, Jae-Sung (Department of Neurology, Hallym University Sacred Heart Hospital, Anyang, South Korea) ; Shiozawa, Masayuki (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Koga, Masatoshi (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Li, Linxin (University of Oxford. Centre for Prevention of Stroke and Dementia) ; Lovelock, Caroline (University of Oxford. Centre for Prevention of Stroke and Dementia) ; Chabriat, Hugues (Département Hospitalo-Universtaire NeuroVasc, University Paris Diderot, and INSERM U1141, Paris, France) ; Hennerici, Michael (Department of Neurology, Universitätsmedizin Mannheim, University of Heidelberg, Mannheim, Germany) ; Wong, Yuen Kwun (Division of Neurology, Department of Medicine, The University of Hong Kong, Hong Kong) ; Mak, Henry Ka Fung (Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong) ; Prats-Sánchez, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Martínez-Domeño, Alejandro (Institut d'Investigació Biomèdica Sant Pau) ; Inamura, Shigeru (Department of Neurosurgery, Kushiro City General Hospital, Kushiro, Japan) ; Yoshifuji, Kazuhisa (Department of Neurosurgery, Kushiro City General Hospital, Kushiro, Japan) ; Arsava, Ethem Murat (Harvard Medical School) ; Horstmann, Solveig (Heidelberg University Hospital (Alemanya)) ; Purrucker, Jan (Heidelberg University Hospital (Alemanya)) ; Lam, Bonnie Yin Ka (Therese Pei Fong Chow Research Centre for Prevention of Dementia) ; Wong, Adrian (Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong) ; Kim, Young Dae (Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea) ; Song, Tae-Jin (Department of Neurology, Ewha Womans University College of Medicine, Seoul, South Korea) ; Schrooten, Maarten (Center for Brain and Disease Research, VIB, Leuven, Belgium) ; Lemmens, Robin (Experimental Neurology and Leuven Institute for Neuroscience and Disease, Katholieke Universiteit Leuven, University of Leuven, Laboratory of Neurobiology, Leuven, Belgium) ; Eppinger, Sebastian (Department of Neurology, Medical University of Graz, Graz, Austria) ; Gattringer, Thomas (Department of Neurology, Medical University of Graz, Graz, Austria) ; Uysal, Ender (Department of Neurology, Demiroglu Bilim University, Istanbul, Turkey) ; Tanriverdi, Zeynep (Department of Neurology, Demiroglu Bilim University, Istanbul, Turkey) ; Bornstein, Natan M. (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ; Assayag, Einor Ben (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ; Hallevi, Hen (Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel) ; Tanaka, Jun (Division of Neurology, Department of Internal Medicine, Saga University Faculty of Medicine, Nabeshima, Saga, Japan) ; Hara, Hideo (Division of Neurology, Department of Internal Medicine, Saga University Faculty of Medicine, Nabeshima, Saga, Japan) ; Coutts, Shelagh B. (Calgary Stroke Program, Department of Clinical Neurosciences, Radiology and Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada) ; Hert, Lisa (Department of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland) ; Polymeris, Alexandros (Department of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland) ; Seiffge, David J. (Bern University Hospital) ; Lyrer, Philippe (Department of Neurology and Stroke Centre, University Hospital Basel and University of Basel, Basel, Switzerland) ; Algra, Ale (Department of Neurology and Neurosurgery, Utrecht Stroke Centre, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands) ; Kappelle, Jaap (Department of Neurology and Neurosurgery, Utrecht Stroke Centre, University Medical Center Utrecht and Utrecht University, Utrecht, Netherlands) ; Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences, School of Clinical Sciences, University of Edinburgh, Edinburgh, UK) ; Jäger, Hans Rolf (Lysholm Department of Neuroradiology and the Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK) ; Lip, Gregory Y H. (Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark) ; Mattle, Heinrich P. (Bern University Hospital) ; Panos, Leonidas D. (Bern University Hospital) ; Mas, Jean-Louis (Department of Neurology, Sainte-Anne Hospital, Paris Descartes University, INSERM U1266, Paris, France) ; Legrand, Laurence (Sainte-Anne Hospital, Paris Descartes University, INSERM U1266, Paris, France) ; Karayiannis, Christopher (Peninsula Clinical School, Peninsula Health, Monash University, Melbourne, VIC, Australia) ; Phan, Thanh (Stroke and Ageing Research Group, School of Clinical Sciences at Monash Health, Monash University, Melbourne, VIC, Australia) ; Gunkel, Sarah (Department of Neurology, University Hospital of Würzburg, Josef-Schneider Strasse 11, Würzburg, Germany) ; Christ, Nicolas (Department of Neurology, University Hospital of Würzburg, Josef-Schneider Strasse 11, Würzburg, Germany) ; Abrigo, Jill (Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Leung, Thomas (Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Chu, Winnie (Department of Imaging and Interventional Radiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Chappell, Francesca (UK Dementia Institute at the University of Edinburgh, School of Clinical Sciences, University of Edinburgh, Edinburgh, UK) ; Makin, Stephen (Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, UK) ; Hayden, Derek (The Neurovascular Research Unit and Health Research Board, Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland) ; Williams, David J. (Beaumont Hospital (Dublín, Irlanda)) ; Kooi, M. Eline (Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, Netherlands) ; van Dam-Nolen, Dianne H. K. (University Medical Centre (Rotterdam, Netherlands)) ; Barbato, Carmen (University College London Hospitals NHS Trust) ; Browning, Simone (University College London Hospitals NHS Trust) ; Wiegertjes, Kim (Radboud University Medical Centre. Department of Neurology) ; Tuladhar, Anil M. (Radboud University Medical Center (Nijmegen, Països Baixos)) ; Maaijwee, Noortje (Lucerne State Hospital (Suïssa)) ; Guevarra, Christine (National Neuroscience Institute (Singapore)) ; Yatawara, Chathuri (National Neuroscience Institute (Singapore)) ; Mendyk, Anne-Marie (University of Lille) ; Delmaire, Christine (University of Lille) ; Köhler, Sebastian (Maastricht University. Department of Psychiatry and Neuropsychology) ; van Oostenbrugge, Robert (Maastricht University Medical Centre) ; Zhou, Ying (Department of Neurology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China) ; Xu, Chao (Department of Neurology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China) ; Hilal, Saima (National University Health System (Singapore)) ; Gyanwali, Bibek (National University Health System (Singapore)) ; Chen, Christopher (National University Health System (Singapore)) ; Lou, Min (Department of Neurology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China) ; Staals, Julie (Department of Neurology, CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, Netherlands) ; Bordet, Régis (University of Lille, Inserm, CHU de Lille, Degenerative and vascular cognitive disorders U1171, Lille, France) ; Kandiah, Nagaendran (Department of Neurology, National Neuroscience Institute, Singapore, Singapore) ; de Leeuw, Frank-Erik (Radboud University Medical Centre. Department of Neurology) ; Simister, Robert (University College London Hospitals NHS Trust) ; van der Lugt, Aad (Department of Radiology and Nuclear Medicine, Erasmus Medical Centre, University Medical Centre, Rotterdam, Netherlands) ; Kelly, Peter J. (The Neurovascular Research Unit and Health Research Board, Stroke Clinical Trials Network Ireland, University College Dublin, Dublin, Ireland) ; Wardlaw, Joanna (University of Edinburgh. UK Dementia Institute) ; Soo, Yannie (Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong) ; Fluri, Felix (University Hospital of Würzburg (Würzburg, Alemanya)) ; Srikanth, Velandai (Peninsula Clinical School, Peninsula Health, Monash University, Melbourne, VIC, Australia) ; Calvet, David (Department of Neurology, Sainte-Anne Hospital, Paris Descartes University, INSERM U1266, Paris, France) ; Jung, Simon (Bern University Hospital) ; Kwa, Vincent I H. (Department of Neurology, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands) ; Engelter, Stefan T. (Neurology and Neurorehabilitation, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, Switzerland) ; Peters, Nils (Neurology and Neurorehabilitation, University Department of Geriatric Medicine Felix Platter, University of Basel, Basel, Switzerland) ; Smith, Eric E. (Calgary Stroke Program, Department of Clinical Neurosciences, Radiology and Community Health Sciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada) ; Yakushiji, Yusuke (Division of Neurology, Department of Internal Medicine, Saga University Faculty of Medicine, Nabeshima, Saga, Japan) ; Orken, Dilek Necioglu (Department of Neurology, Demiroglu Bilim University, Istanbul, Turkey) ; Fazekas, Franz (Department of Neurology, Medical University of Graz, Graz, Austria) ; Thijs, Vincent (University Hospitals Leuven (Bèlgica)) ; Heo, Ji Hoe (Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea) ; Mok, Vincent (Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong) ; Veltkamp, Roland (Heidelberg University Hospital (Alemanya)) ; Ay, Hakan (Harvard Medical School) ; Imaizumi, Toshio (Department of Neurosurgery, Kushiro City General Hospital, Kushiro, Japan) ; Gómez-Ansón, Beatriz (Institut d'Investigació Biomèdica Sant Pau) ; Lau, Kui Kai (Division of Neurology, Department of Medicine, The University of Hong Kong, Hong Kong) ; Jouvent, Eric (Département Hospitalo-Universtaire NeuroVasc, University Paris Diderot, and INSERM U1141, Paris, France) ; Rothwell, Peter M. (University of Oxford. Centre for Prevention of Stroke and Dementia) ; Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Bae, Hee-Joon (Department of Neurology, Seoul National University Bundang Hospital, Seoul National University School of Medicine, Seongnam, South Korea) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Werring, David J. (Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK) ; Universitat Autònoma de Barcelona
Cerebral microbleeds are a neuroimaging biomarker of stroke risk. A crucial clinical question is whether cerebral microbleeds indicate patients with recent ischaemic stroke or transient ischaemic attack in whom the rate of future intracranial haemorrhage is likely to exceed that of recurrent ischaemic stroke when treated with antithrombotic drugs. [...]
2019 - 10.1016/S1474-4422(19)30197-8
The Lancet neurology, Vol. 18 (july 2019) , p. 653-665  
3.
10 p, 990.6 KB Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds / Charidimou, Andreas ; Imaizumi, Toshio ; Moulin, Solene ; Biffi, Alessandro ; Samarasekera, Neshika ; Yakushiji, Yusuke ; Peeters, Andre ; Vandermeeren, Yves ; Laloux, Patrice ; Baron, Jean-Claude ; Hernandez-Guillamon, Mar ; Montaner, Joan (Hospital Universitari Vall d'Hebron) ; Casolla, Barbara ; Gregoire, Simone M. ; Kang, Dong-Wha ; Kim, Jong S. ; Naka, H. ; Smith, Eric E. ; Viswanathan, Anand ; Jäger, Hans Rolf ; Al-Shahi Salman, Rustam ; Greenberg, Steven M. ; Cordonnier, Charlotte ; Werring, David J. ; Universitat Autònoma de Barcelona
We evaluated recurrent intracerebral hemorrhage (ICH) risk in ICH survivors, stratified by the presence, distribution, and number of cerebral microbleeds (CMBs) on MRI (i. e. , the presumed causal underlying small vessel disease and its severity). [...]
2017 - 10.1212/WNL.0000000000004259
Neurology, Vol. 89 (august 2017) , p. 820-829  
4.
11 p, 168.8 KB Genetic variants in CETP increase risk of intracerebral hemorrhage / Anderson, Christopher D. (Broad Institute of MIT and Harvard) ; Falcone, Guido J. (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Phuah, Chia-Ling (Broad Institute of MIT and Harvard) ; Radmanesh, Farid (Broad Institute of MIT and Harvard) ; Brouwers, H. Bart (Broad Institute of MIT and Harvard) ; Battey, Thomas W. K. (Broad Institute of MIT and Harvard) ; Biffi, Alessandro (Division of Psychiatry, Department of Psychiatry, MGH) ; Peloso, Gina M. (Broad Institute of MIT and Harvard) ; Liu, Dajiang J. (Institute of Personalized Medicine, Penn State College of Medicine) ; Ayres, Alison M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Goldstein, Joshua N. (Department of Emergency Medicine, MGH) ; Viswanathan, Anand (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Greenberg, Steven M. (J. Philip Kistler Stroke Research Center, Department of Neurology, MGH) ; Selim, Magdy (Beth Israel Deaconess Medical Center) ; Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ; Brown, Devin L. (University of Michigan Health System) ; Worrall, Bradford B. (University of Virginia Health System) ; Silliman, Scott L. (University of Florida College of Medicine) ; Tirschwell, David L. (University of Washington) ; Flaherty, Matthew L. (University of Cincinnati College of Medicine) ; Kraft, Peter (Departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health) ; Jagiella, Jeremiasz M. (Jagiellonian University Medical College) ; Schmidt, Helena (Medical University Graz) ; Hansen, Björn M. (Skåne University Hospital (Suècia)) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cuadrado-Godia, Elisa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soriano Tàrraga, Carolina (Institut Hospital del Mar d'Investigacions Mèdiques) ; van Nieuwenhuizen, Koen M. (University Medical Center Utrecht) ; Klijn, Catharina J. M. (Donders Institute for Brain, Cognition, and Behavior, Radboud University Medical Center) ; Rannikmae, Kristiina (University of Edinburgh) ; Samarasekera, Neshika (University of Edinburgh) ; Salman, Rustam Al-Shahi (University of Edinburgh) ; Sudlow, Catherine L. (University of Edinburgh) ; Deary, Ian J. (University of Edinburgh) ; Morotti, Andrea (Neurology Clinic, University of Brescia) ; Pezzini, Alessandro (Neurology Clinic, University of Brescia) ; Pera, Joanna (Jagiellonian University Medical College) ; Urbanik, Andrzej (Jagiellonian University Medical College) ; Pichler, Alexander (Medical University of Graz) ; Enzinger, Christian (Medical University of Graz) ; Norrving, Bo (Skåne University Hospital (Suècia)) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roquer González, Jaume (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lindgren, Arne (Skåne University Hospital (Suècia)) ; Slowik, Agnieszka (Jagiellonian University Medical College) ; Schmidt, Reinhold (Medical University of Graz) ; Kidwell, Chelsea S. (University of Arizona) ; Kittner, Steven J. (Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine) ; Waddy, Salina P. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Langefeld, Carl D. (Wake Forest University) ; Abecasis, Goncalo (University of Michigan School of Public Health) ; Willer, Cristen J. (University of Michigan Medical School) ; Kathiresan, Sekar (Cardiovascular Disease Prevention Center, MGH) ; Woo, Daniel (University of Cincinnati College of Medicine) ; Rosand, Jonathan (Broad Institute of MIT and Harvard) ; Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)
In observational epidemiologic studies, higher plasma high-density lipoprotein cholesterol (HDL-C) has been associated with increased risk of intracerebral hemorrhage (ICH). DNA sequence variants that decrease cholesteryl ester transfer protein (CETP) gene activity increase plasma HDL-C; as such, medicines that inhibit CETP and raise HDL-C are in clinical development. [...]
2016 - 10.1002/ana.24780
Annals of neurology, Vol. 80 (october 2016) , p. 730-740  

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