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18 p, 1.9 MB |
The use of genome wide association methods to investigate pathogenicity, population structure and serovar in Haemophilus parasuis
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Howell, Kate J. (University of Cambridge. Department of Veterinary Medicine) ;
Weinert, Lucy A. (University of Cambridge. Department of Veterinary Medicine) ;
Chaudhuri, Roy R. (University of Sheffield. Department of Molecular Biology and Biotechnology) ;
Luan, Shi-Lu (University of Cambridge. Department of Veterinary Medicine) ;
Peters, Sarah E. (University of Cambridge. Department of Veterinary Medicine) ;
Corander, Jukka (University of Helsinki. Department of Mathematics and Statistics) ;
Harris, David (Wellcome Trust Sanger Institute (Regne Unit)) ;
Angen, Øystein (Norwegian Veterinary Institute) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bensaid, Albert (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Williamson, Susanna M. (Animal Health and Veterinary Laboratories Agency) ;
Parkhill, Julian (Wellcome Trust Sanger Institute (Regne Unit)) ;
Langford, Paul R. (Imperial College London. Department of Medicine, Section of Paediatrics) ;
Rycroft, Andrew N. (The Royal Veterinary College) ;
Wren, Brendan W. (London School of Hygiene & Tropical Medicine. Faculty of Infectious & Tropical Diseases) ;
Holden, Matthew T. G. (University of St. Andrews. School of Medicine) ;
Tucker, Alexander W. (University of Cambridge. Department of Veterinary Medicine) ;
Maskell, Duncan J.. (University of Cambridge. Department of Veterinary Medicine)
Haemophilus parasuis is the etiologic agent of Glässer's disease in pigs and causes devastating losses to the farming industry. Whilst some hyper-virulent isolates have been described, the relationship between genetics and disease outcome has been only partially established. [...]
2014 -  10.1186/1471-2164-15-1179
BMC genomics, Vol. 15 (december 2014)
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17 p, 867.3 KB |
Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes
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Clop, Alex (Centre de Recerca en Agrigenòmica) ;
Sharaf, Abdoallah (Ain Shams University. Faculty of agriculture) ;
Castelló Farré, Anna (Centre de Recerca en Agrigenòmica) ;
Ramos-Onsins, Sebastian (Centre de Recerca en Agrigenòmica) ;
Cirera, Susanna (University of Copenhagen. Department of Veterinary and Animal Sciences) ;
Mercadé Carceller, Anna (Centre de Recerca en Agrigenòmica) ;
Derdak, Sophia (Universitat Pompeu Fabra) ;
Beltran i Agulló, Sergi (Universitat Pompeu Fabra) ;
Huisman, Abe (Hypor BV (The Netherlands)) ;
Fredholm, Merete (University of Copenhagen. Department of Veterinary and Animal Sciences) ;
van As, Pieter (Hendrix Genetics Research & Technology Centre) ;
Sánchez Bonastre, Armando (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Taste receptors (TASRs) are essential for the body's recognition of chemical compounds. In the tongue, TASRs sense the sweet and umami and the toxin-related bitter taste thus promoting a particular eating behaviour. [...]
2016 - 10.1186/s12864-016-2972-z
BMC genomics, Vol. 17 (August 2016) , art. 685
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14 p, 1.2 MB |
Piglet nasal microbiota at weaning may influence the development of Glässer's disease during the rearing period
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Correa-Fiz, Florencia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Fraile, Lorenzo (Universitat de Lleida. Departament de Producció Animal) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
The microbiota, the ensemble of microorganisms on a particular body site, has been extensively studied during the last few years, and demonstrated to influence the development of many diseases. However, these studies focused mainly on the human digestive system, while the populations in the respiratory tract have been poorly assessed, especially in pigs. [...]
2016 - 10.1186/s12864-016-2700-8
BMC genomics, Vol. 17 (may 2016)
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9 p, 279.8 KB |
Genotypic and phenotypic features of all Spanish patients with McArdle disease : a 2016 update
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Santalla, Alfredo (Instituto de Investigación Sanitaria Hospital 12 de Octubre (i+12)) ;
Nogales, Gisela (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Encinar, Alberto Blázquez (Hospital Universitario 12 de Octubre (Madrid)) ;
Vieitez, Irene (Hospitalario Universitario de Vigo) ;
González-Quintana, Adrian (Instituto de Salud Carlos III) ;
Serrano-Lorenzo, Pablo (Instituto de Salud Carlos III) ;
Consuegra-García, Inés (Hospital Universitario 12 de Octubre (Madrid)) ;
Asensio, Sara (Instituto de Salud Carlos III) ;
Ballester-Lopez, Alfonsina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pintos-Morell, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Coll-Cantí, Jaume (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pareja-Galeano, Helios (Universidad Europea de Madrid) ;
Díez-Bermejo, Jorge (Universidad Europea de Madrid) ;
Pérez Ruiz, Margarita (Universidad Europea de Madrid) ;
Andreu Périz, Antoni Lluís (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pinós Figueras, Tomàs (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arenas, Joaquín (Instituto de Salud Carlos III) ;
Martín, Miguel A. (Hospital Universitario 12 de Octubre (Madrid)) ;
Lucia, Alejandro (Universidad Europea de Madrid)
We recently described the genotype/phenotype features of all Spanish patients diagnosed with McArdle disease as of January 2011 (n = 239, prevalence of ~1/167,000) (J Neurol Neurosurg Psychiatry 2012;83:322-8). [...]
2017 - 10.1186/s12864-017-4188-2
BMC genomics, Vol. 18 (november 2017)
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18 p, 1.7 MB |
Expansion of the SOS regulon of Vibrio cholerae through extensive transcriptome analysis and experimental validation
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Krin, Evelyne (Institut Pasteur. Département Génomes et Génétique) ;
Pierlé, Sebastian Aguilar (Institut Pasteur. Département Génomes et Génétique) ;
Sismeiro, Odile (Institut Pasteur. Biomics Center for Innovation and Technological Research) ;
Jagla, Bernd (Institut Pasteur. UtechS CB and Hub Bioinformatique et Biostatistique) ;
Dillies, Marie-Agnès (Institut Pasteur. Hub Bioinformatique et Biostatistique) ;
Varet, Hugo (Institut Pasteur. Biomics Center for Innovation and Technological Research) ;
Irazoki, Oihane (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Campoy Sánchez, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Rouy, Zoé (Université Evry-Val-d'Essonne. Institut de Biologie François Jacob) ;
Cruveiller, Stéphane (Université Evry-Val-d'Essonne. Institut de Biologie François Jacob) ;
Médigue, Claudine (Université Evry-Val-d'Essonne. Institut de Biologie François Jacob) ;
Coppée, Jean-Yves (Institut Pasteur. Biomics Center for Innovation and Technological Research) ;
Mazel, Didier (Institut Pasteur. Département Génomes et Génétique)
The SOS response is an almost ubiquitous response of cells to genotoxic stresses. The full complement of genes in the SOS regulon for Vibrio species has only been addressed through bioinformatic analyses predicting LexA binding box consensus and in vitro validation. [...]
2018 - 10.1186/s12864-018-4716-8
BMC genomics, Vol. 19 (May 2018) , art. 373
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11 p, 2.9 MB |
Flexible comparative genomics of prokaryotic transcriptional regulatory networks
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Kılıç, Sefa (University of Maryland Baltimore County) ;
Sánchez-Osuna, Miquel (Universitat Autònoma de Barcelona) ;
Collado-Padilla, Antonio (Universitat Autònoma de Barcelona) ;
Barbé García, Jordi (Universitat Autònoma de Barcelona) ;
Erill, Ivan (University of Maryland Baltimore County)
Comparative genomics methods enable the reconstruction of bacterial regulatory networks using available experimental data. In spite of their potential for accelerating research into the composition and evolution of bacterial regulons, few comparative genomics suites have been developed for the automated analysis of these regulatory systems. [...]
2020 - 10.1186/s12864-020-06838-x
BMC genomics, Vol. 21, Suppl. 5 (December 2020) , art. 466
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12 p, 1.3 MB |
The genetic impact of an Ebola outbreak on a wild gorilla population
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Fontsere, Claudia (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Frandsen, Peter (University of Copenhagen. Department of Biology. Section for Computational and RNA Biology) ;
Hernandez Rodriguez, Jessica (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Niemann, Jonas (University of Copenhagen. Center for Evolutionary Hologenomics. The GLOBE Institute) ;
Hjorth Scharff-Olsen, Camilla (University of Copenhagen. Center for Evolutionary Hologenomics. The GLOBE Institute) ;
Vallet, Dominique (Centre National de la Recherche Scientifique. University of Rennes. ECOBIO: Ecosystems, Biodiversity, Evolution) ;
Le Gouar, Pascaline (Centre National de la Recherche Scientifique. University of Rennes. ECOBIO: Ecosystems, Biodiversity, Evolution) ;
Ménard, Nelly (Centre National de la Recherche Scientifique. University of Rennes. ECOBIO: Ecosystems, Biodiversity, Evolution) ;
Navarro, Arcadi, 1969- (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Siegismund, Hans R. (University of Copenhagen. Department of Biology. Section for Computational and RNA Biology) ;
Hvilsom, Christina (Copenhagen Zoo. Research and Conservation) ;
Gilbert, M. Thomas P. (University of Copenhagen. Center for Evolutionary Hologenomics. The GLOBE Institute) ;
Kuhlwilm, Martin (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Hughes, David (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont)
Background: Numerous Ebola virus outbreaks have occurred in Equatorial Africa over the past decades. Besides human fatalities, gorillas and chimpanzees have also succumbed to the fatal virus. The 2004 outbreak at the Odzala-Kokoua National Park (Republic of Congo) alone caused a severe decline in the resident western lowland gorilla (Gorilla gorilla gorilla) population, with a 95% mortality rate. [...]
2021 - 10.1186/s12864-021-08025-y
BMC genomics, Vol. 22 (October 2021) , art. 735
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