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2 p, 536.6 KB |
Correction to : Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease: an open cohort multivariable and propensity score analysis from Funen, Denmark
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Ali, M. Sanni (Saint Paul Hospital Millennium Medical College. Department of Public Health) ;
Ernst, Martin (University of Southern Denmark. Department of Public Health, Clinical Pharmacology and Pharmacy) ;
Robinson, Danielle E. (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Caskey, Fergus (University of Bristol. Population Health Sciences) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit) ;
Ben-Shlomo, Yoav (University of Bristol. Population Health Sciences) ;
Nybo, Mads (Odense University Hospital (Dinamarca)) ;
Rubin, Katrine H. (University of Southern Denmark. Department of Health) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit) ;
Javaid, M. K. (MRC Lifecourse Epidemiology Unit) ;
Hermann, Anne P. (Odense University Hospital (Dinamarca)) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
2021 -  10.1007/s11657-021-01001-9
Archives of Osteoporosis, Vol. 16 (september 2021)
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12 p, 944.6 KB |
Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease : an open cohort multivariable and propensity score analysis from Funen, Denmark
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Ali, M. Sanni (London School of Hygiene and Tropical Medicine. Department of Non-communicable Disease Epidemiology) ;
Ernst, Martin (University of Southern Denmark. Department of Public Health, Clinical Pharmacology and Pharmacy) ;
Robinson, Danielle E. (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Caskey, Fergus (University of Bristol. Population Health Sciences) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit) ;
Ben-Shlomo, Yoav (University of Bristol. Population Health Sciences) ;
Nybo, Mads (Odense University Hospital (Dinamarca)) ;
Rubin, Katrine H. (University of Southern Denmark. Department of Health) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit) ;
Javaid, M. K. (MRC Lifecourse Epidemiology Unit) ;
Hermann, Anne P. (Odense University Hospital (Dinamarca)) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
Bisphosphonates are contraindicated in moderate-to-severe chronic kidney disease patients. However, they are used to prevent fragility fractures in patients with impaired kidney function, despite a lack of evidence on their effects on bone density in these patients. [...]
2020 - 10.1007/s11657-020-00746-z
Archives of Osteoporosis, Vol. 15 (june 2020)
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8 p, 535.7 KB |
The impact of rheumatoid arthritis on the risk of adverse events following joint replacement : a real-world cohort study
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Burn, Edward (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Edwards, Christopher J. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Murray, David W. (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Silman, Alan (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Pinedo-Villanueva, Rafael (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Universitat Autònoma de Barcelona
To assess whether rheumatoid arthritis (RA) is associated with a greater risk of adverse events following total knee replacement (TKR) and total hip replacement (THR) than osteoarthritis (OA). Individuals with a diagnosis of RA or OA were identified using primary care records. [...]
2018 - 10.2147/CLEP.S160347
Clinical Epidemiology, Vol. 10 (june 2018) , p. 697-704
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15 p, 1.4 MB |
Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data : a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database
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Khalid, Sara (University of Oxford. NIHR Biomedical Research Centre) ;
Calderon-Larrañaga, Sara (Family and Community Medicine Teaching Unit of Granada. Cartuja University Health Centre. Andalusian Health Service (SAS), Granada, Spain) ;
Hawley, Samuel (University of Oxford. NIHR Biomedical Research Centre) ;
Ali, M. Sanni (London School of Hygiene and Tropical Medicine, London, United Kingdom) ;
Judge, Andrew (Bristol NIHR Biomedical Research Centre (Bristol, Regne Unit)) ;
Arden, N. K (University of Oxford. Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis) ;
van Staa, Tjeerd (Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands) ;
Cooper, Cyrus (NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom) ;
Javaid, Muhammad Kassim (University of Oxford. NIHR Biomedical Research Centre) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. We investigated two primary care records databases covering UK National Health Service (Clinical Practice Research Datalink, CPRD) and Catalan healthcare (Information System for Research in Primary Care, SIDIAP) patients during 1995-2014 and 2006-2014, respectivey. [...]
2018 - 10.2147/CLEP.S164112
Clinical Epidemiology, Vol. 10 (october 2018) , p. 1417-1431
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8 p, 182.5 KB |
Impact of TNF inhibitor therapy on joint replacement rates in rheumatoid arthritis : a matched cohort analysis of BSRBR-RA UK registry data
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Hawley, Samuel (University of Oxford. Centre for Statistics in Medicine) ;
Ali, M. Sanni (Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK) ;
Cordtz, René (The Parker Institute, Copenhagen University Hospital Copenhagen) ;
Dreyer, Lene (Department of Clinical Medicine, Aalborg University, Aalborg, Denmark) ;
Edwards, Christopher J. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton) ;
Judge, Andrew (Translational Health Sciences, University of Bristol, Bristol) ;
Hyrich, Kimme (University of Manchester) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona)
Previous ecological data suggest a decline in the need for joint replacements in RA patients following the introduction of TNF inhibitor (TNFi) therapy, although patient-level data are lacking. Our primary aim was to estimate the association between TNFi use and subsequent incidence of total hip replacement (THR) and total knee replacement. [...]
2019 - 10.1093/rheumatology/key424
Rheumatology, Vol. 58 (january 2019) , p. 1168-1175
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9 p, 289.6 KB |
The effect of rheumatoid arthritis on patient-reported outcomes following knee and hip replacement : evidence from routinely collected data
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Burn, Edward (Nuffield University of Oxford. Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Edwards, Christopher J. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Murray, David W. (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Silman, Alan (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Pinedo-Villanueva, Rafael (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona)
To compare outcomes of total knee replacement (TKR) and total hip replacement (THR) for individuals with RA and OA. We performed a cohort study using routinely collected data. Oxford Knee Score, Oxford Hip Score, and EuroQol 5-dimension 3-level (EQ-5D-3L) questionnaires were collected before and 6 months after surgery. [...]
2019 - 10.1093/rheumatology/key409
Rheumatology, Vol. 58 (january 2019) , p. 1016-1024
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5 p, 216.0 KB |
Lifetime risk of knee and hip replacement following a diagnosis of RA : findings from a cohort of 13 961 patients from England
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Burn, Edward (Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences. University of Oxford) ;
Edwards, Christopher J. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Murray, David W. (Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences. University of Oxford) ;
Silman, Alan (Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences. University of Oxford) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit. Southampton University) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit. Southampton University) ;
Pinedo-Villanueva, Rafael (Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences. University of Oxford) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona)
Objective: To estimate the lifetime risk of knee and hip replacement following a diagnosis of RA. Methods: The analysis was undertaken using routinely collected data from the English NHS. Diagnosis of RA was identified using primary care records, with knee and hip replacement observed in linked hospital records. [...]
2019 - 10.1093/rheumatology/kez143
Rheumatology, Vol. 58 (2019) , p. 1950-1954
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10 p, 1003.4 KB |
Trends and determinants of length of stay and hospital reimbursement following knee and hip replacement : evidence from linked primary care and NHS hospital records from 1997 to 2014
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Burn, Edward (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (UK)) ;
Edwards, Christopher J. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Murray, David W. (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (UK)) ;
Silman, Alan (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (UK)) ;
Cooper, Cyrus (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (UK)) ;
Arden, N. K (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (UK)) ;
Pinedo-Villanueva, Rafael (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (UK)) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona)
To measure changes in length of stay following total knee and hip replacement (TKR and THR) between 1997 and 2014 and estimate the impact on hospital reimbursement, all else being equal. Further, to assess the degree to which observed trends can be explained by improved efficiency or changes in patient profiles. [...]
2018 - 10.1136/bmjopen-2017-019146
BMJ open, Vol. 8, Issue 1 (January 2018) , article e019146
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None, 1.3 MB |
The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee : a population-based cohort study
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Bayliss, Lee E. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford) ;
Culliford, David (NIHR CLAHRC Wessex Methodological Hub, University of Southampton, Southampton, UK) ;
Monk, A. Paul (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Glyn-Jones, Sion (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK) ;
Carr, Andrew J. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK) ;
Beard, David J. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK) ;
Price, Andrew J. (Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, NIHR Biomedical Research Unit, University of Oxford, Oxford, UK)
Total joint replacements for end-stage osteoarthritis of the hip and knee are cost-effective and demonstrate significant clinical improvement. However, robust population based lifetime-risk data for implant revision are not available to aid patient decision making, which is a particular problem in young patient groups deciding on best-timing for surgery. [...]
2017 - 10.1016/S0140-6736(17)30059-4
The Lancet (British), Vol. 389 (april 2017) , p. 1424-1430
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7 p, 376.1 KB |
Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients : population-based longitudinal study
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Hawley, Samuel (University of Oxford) ;
Javaid, M. Kassim (MRC Lifecourse Epidemiology Unit, University of Southampton) ;
Prieto-Alhambra, Daniel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lippett, Janet (Royal Berkshire NHS Foundation Trust, Reading) ;
Sheard, Sally (University of Oxford) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, University of Southampton) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, University of Southampton) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit, University of Southampton) ;
Universitat Autònoma de Barcelona
Objectives: to evaluate orthogeriatric and nurse-led fracture liaison service (FLS) models of post-hip fracture care in terms of impact on mortality (30 days and 1 year) and second hip fracture (2 years). [...]
2016 - 10.1093/ageing/afv204
Age and Ageing, Vol. 45 (january 2016) , p. 236-242
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