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7 p, 715.4 KB |
Safety and efficacy of self-administered inhaled loxapine (ADASUVE) in agitated patients outside the hospital setting : Protocol for a phase IV, single-arm, open-label trial
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Gil, Emilio (Ferrer Internacional. S.A.) ;
Garcia-Alonso, Fernando (Ferrer Internacional. S.A.) ;
Boldeanu, Anca (Ferrer Internacional. S.A.) ;
Baleeiro Teixeira, Thaïs (Ferrer Internacional. S.A.) ;
Tordera, Vicente (Hospital Lluís Alcanyis) ;
Viciedo, Ramón Palmer (Hospital Provincial de Castelló) ;
Salgado Serrano, Dr Purificación (Hospital del Mar (Barcelona, Catalunya)) ;
Domingo Ribas, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Corripio, Iluminada (Institut d'Investigació Biomèdica Sant Pau) ;
Montes, José Manuel (Hospital Universitario Ramón y Cajal (Madrid)) ;
Lauffer, Javier Correas (Hospital Univ de Henares) ;
Murugarrem, Salvador Ruiz (Hospital Príncipe de Asturias) ;
García, Santiago Ovejero (Hospital Universitario Fundación Jiménez Díaz) ;
Mora, Fernando (Hospital Universitario Infanta Leonor) ;
López, Presentación Ataz (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Navas, Andrés Fontalba (Hospital la Inmaculada) ;
Pinto, Ana Mª González (Hospital Santiago Apóstol) ;
Martínez, Ricardo (Hospital Virgen Del Mirón) ;
Castrillo, César García (Complejo Hospitalario de Jaen) ;
Toledo, Francisco (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
González, Emilio (Hermanas Hospitalarias Sociosanitario Palencia) ;
Franco Martín, Manuel (Complejo Asistencial Zamora) ;
Drasovean, Nicolae Virgil (Spitalul de Psihiatrie 'Elisabeta Doamna' Galati) ;
Dahl, Nils Hâvard (Helse Nord-Trøndelag HV Sykehuset Levanger) ;
Skagen, Bo (Spesialistesenteret På Straume-Helsesenteret) ;
Zilles, David (Klinik Für Psychiatrie und Psychotherapie der Universitätsmedizin Göttingen) ;
Zwanzger, Peter (Allgemeinpsychiatrie und Psychosomatik) ;
Juckel, Georg (LWL-Universitätsklinikum Bochum der Ruhr-Universität Bochum) ;
Kahl, Kai G. (Medizinische Hochschule Hannover) ;
Messer, Thomas (Fachklinik Für Psychiatrie) ;
Kasper, Siegfried (Medizinische Universität Wien Universitätsklinik Für Psychiatrie und Psychotherapie) ;
Universitat Autònoma de Barcelona
There is a need for fast-acting, non-injection antiagitation treatments that are well tolerated and can be used outside of healthcare facilities. In phase II/III trials, an inhaled formulation of loxapine (ADASUVE®), a well-established, first-generation antipsychotic agent, provided rapid control of mild to moderate agitation in the hospital setting. [...]
2018 -  10.1136/bmjopen-2017-020242
BMJ open, Vol. 8 Núm. 10 (january 2018) , p. e020242
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10 p, 598.4 KB |
Values and preferences of men for undergoing prostate-specific antigen screening for prostate cancer : a systematic review
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Vernooij, Robin W.M. (Netherlands Comprehensive Cancer Organisation) ;
Lytvyn, Lyubov (McMaster University (Canadà)) ;
Pardo-Hernandez, Hector (Institut d'Investigació Biomèdica Sant Pau) ;
Albarqouni, Loai (Bond University) ;
Canelo Aybar, Carlos Gilberto (Universidad Peruana de Ciencias Aplicadas) ;
Campbell, Karen (McMaster University (Canadà)) ;
Agoritsas, Thomas (Geneva University Hospitals) ;
Universitat Autònoma de Barcelona
To investigate men's values and preferences regarding prostate-specific antigen (PSA)-based screening for prostate cancer. Systematic review. We searched MEDLINE, EMBASE, PsycINFO and grey literature up to 2 September 2017. [...]
2018 - 10.1136/bmjopen-2018-025470
BMJ open, Vol. 8 Núm. 9 (2018) , p. e025470
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7 p, 227.7 KB |
Delayed antibiotic prescribing for respiratory tract infections : Protocol of an individual patient data meta-analysis
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Stuart, Beth (University of Southampton) ;
Hounkpatin, Hilda (University of Southampton) ;
Becque, Taeko (University of Southampton) ;
Yao, Guiqing (University of Leicester) ;
Zhu, Shihua (University of Southampton) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Altiner, Attila (University of Rostock) ;
Arroll, Bruce (University of Auckland) ;
Böhning, Dankmar (University of Southampton) ;
Bostock, Jennifer (King's College London) ;
Bucher, Heiner (University of Basel) ;
De La Poza, Mariam (Institut Català de la Salut) ;
Francis, Nick A. (Cardiff University) ;
Gillespie, David (Cardiff University) ;
Hay, Alastair D. (University of Bristol) ;
Kenealy, Timothy (University of Auckland) ;
Löffler, Christin (Rostock University Medical Center) ;
Mas Dalmau, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Muñoz, Laura (Agència de Qualitat i Avaluació Sanitàries de Catalunya (AQuAS)) ;
Samuel, Kirsty (University of Leeds) ;
Moore, Michael (University of Southampton) ;
Little, Paul (University of Southampton) ;
Universitat Autònoma de Barcelona
Delayed prescribing can be a useful strategy to reduce antibiotic prescribing, but it is not clear for whom delayed prescribing might be effective. This protocol outlines an individual patient data (IPD) meta-analysis of randomised controlled trials (RCTs) and observational cohort studies to explore the overall effect of delayed prescribing and identify key patient characteristics that are associated with efficacy of delayed prescribing. [...]
2019 - 10.1136/bmjopen-2018-026925
BMJ open, Vol. 9 Núm. 1 (january 2019) , p. e026925
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4 p, 197.4 KB |
Health effects of desert dust and sand storms : A systematic review and meta-analysis protocol
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Tobias, Aurelio (Institut d'Avaluació Ambiental i Investigació de l'Aigua (IDAEA)) ;
Karanasiou, Angeliki (Institut d'Avaluació Ambiental i Investigació de l'Aigua (IDAEA)) ;
Amato, Fulvio (Institut d'Avaluació Ambiental i Investigació de l'Aigua (IDAEA)) ;
Roqué i Figuls, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Querol, Xavier (Institut d'Avaluació Ambiental i Investigació de l'Aigua (IDAEA)) ;
Universitat Autònoma de Barcelona
Desert dust concentrations raise concerns about adverse effects on human health. During the last decade, special attention has been given to mineral dust particles from desert dust and sand storms. However, evidence from previous reviews reported inconclusive results on their health effects and the biological mechanism remains unclear. [...]
2019 - 10.1136/bmjopen-2019-029876
BMJ open, Vol. 9 Núm. 7 (january 2019) , p. e029876
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9 p, 746.2 KB |
Extending the RIGHT statement for reporting adapted practice guidelines in healthcare : The RIGHT-Ad@pt Checklist protocol
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Song, Yang (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Darzi, Andrea (American University of Beirut) ;
Ballesteros Silva, Mónica Patricia (Hospital Universitari Vall d'Hebron) ;
Martínez García, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Arayssi, T. (Weill Cornell Medicine-Qatar) ;
Bhaumik, SSoumyadeep (George Institute for Global Health) ;
Chen, Yaolong (WHO Collaborating Centre for Guideline Implementation and Knowledge Translation) ;
Cluzeau, Françoise (Imperial College London) ;
Ghersi, Davina (National Health and Medical Research Council) ;
Padilla, Paulina F. (Universidad de Antofagasta) ;
Langlois, Etienne V. (World Health Organization) ;
Schünemann, Holger J. (McMaster University (Canadà)) ;
Vernooij, Robin W.M. (Netherlands Comprehensive Cancer Organisation (IKNL)) ;
Akl, Elie A. (American University of Beirut) ;
Universitat Autònoma de Barcelona
The adaptation of guidelines is an increasingly used methodology for the efficient development of contextualised recommendations. Nevertheless, there is no specific reporting guidance. The essential Reporting Items of Practice Guidelines in Healthcare (RIGHT) statement could be useful for reporting adapted guidelines, but it does not address all the important aspects of the adaptation process. [...]
2019 - 10.1136/bmjopen-2019-031767
BMJ open, Vol. 9 Núm. 9 (january 2019) , p. e031767
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12 p, 1.7 MB |
Online information in Spanish on probiotics, yoghurt, kefir, kombucha, fibre and prebiotics : an analysis of the quality of information and the certainty of the evidence supporting health claims
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Prados-Bo, Andreu (Universitat Ramon Llull) ;
Rabassa Bonet, Montserrat (Eurecat) ;
Bosch, Mireia (Eurecat) ;
Casino, Gonzalo (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
To examine the certainty of the evidence supporting health claims about probiotics, yoghurt, kefir, kombucha, fibre and prebiotics, and to assess the quality of online information in Spanish. Content analysis. [...]
2022 - 10.1136/bmjopen-2022-063316
BMJ open, Vol. 12 Núm. 8 (january 2022) , p. e063316
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8 p, 435.6 KB |
Effect of synchronous remote-based interventions on suicidal behaviours : protocol for a systematic review and meta-analysis
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Comendador Vázquez, Laura (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Jiménez-Villamizar, María Paola (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Losilla Vidal, Josep Maria (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Sanabria-Mazo, Juan P.. (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Mateo Canedo, Corel (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Cebrià, Ana Isabel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sanz Ruiz, Antoni (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Palao, Diego (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Introduction Suicide is among the leading causes of preventable death worldwide. The impact of suicide affects the personal, social and economic levels. Therefore, its prevention is a priority for public health systems. [...]
2023 - 10.1136/bmjopen-2023-075116
BMJ open, 2023, p. 1-8
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10 p, 1.8 MB |
Socioeconomic inequalities in suicide mortality in Barcelona during the economic crisis (2006-2016) : A time trend study
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López-Contreras, Natalia (Agència de Salut Pública de Barcelona) ;
Rodríguez-Sanz, Maica (Institut d'Investigació Biomèdica Sant Pau) ;
Novoa, Ana M. (Institut d'Investigació Biomèdica Sant Pau) ;
Borrell i Thió, Carme (Institut d'Investigació Biomèdica Sant Pau) ;
Medallo Muñiz, Jordi (Institut de Medicina Legal i Ciències Forenses de Catalunya (IMLCFC)) ;
Gotsens, Mercè (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
This study aimed to analyse trends in socioeconomic inequalities in suicide mortality in Barcelona before and after the start of the economic crisis that started at the end of 2008, including both individual factors and contextual factors of the deceased's neighbourhood of residence. [...]
2019 - 10.1136/bmjopen-2018-028267
BMJ open, Vol. 9 Núm. 8 (january 2019) , p. e028267
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8 p, 533.0 KB |
Rationale and design of the hip fracture accelerated surgical treatment and care track (hip attack) trial : A protocol for an international randomised controlled trial evaluating early surgery for hip fracture patients
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Borges, Flavia K. (Population Health Research Institute) ;
Bhandari, Mohit (McMaster University (Canadà)) ;
Patel, Ameen (McMaster University (Canadà)) ;
Avram, Victoria (McMaster University (Canadà)) ;
Guerra-Farfán, Ernesto (Hospital Universitari Vall d'Hebron) ;
Sigamani, Alben (Narayana Health) ;
Umer, Masood (Aga Khan University) ;
Tiboni, Maria (McMaster University (Canadà)) ;
Adili, Anthony (McMaster University (Canadà)) ;
Neary, John (McMaster University (Canadà)) ;
Tandon, Vikas (McMaster University (Canadà)) ;
Sancheti, Parag K. (Sancheti Institute for Orthopaedics and Rehabilitation (Pune, Índia)) ;
Lawendy, AbdelRahman (London Health Sciences Centre) ;
Jenkinson, Richard (University of Toronto) ;
Ramokgopa, Mmampapatla (University of the Witwatersrand) ;
Biccard, Bruce M (University of Cape Town) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Wang, Chew Yin (University of Malaya) ;
Landoni, Giovanni (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Forget, Patrice (Universitair Ziekenhuis Brussel) ;
Popova, Ekaterine (Institut d'Investigació Biomèdica Sant Pau) ;
Wood, Gavin (Queen's University) ;
Nabi Nur, Aamer (Shifa International Hospital) ;
John, Bobby (Christian Medical College) ;
Ślȩczka, Pawel (SPZOZ) ;
Feibel, Robert J. (University of Ottawa) ;
Balaguer Castro, Mariano (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Deheshi, Benjamin (Sharif Surgical Oncology) ;
Winemaker, Mitchell (McMaster University (Canadà)) ;
De Beer, Justin (McMaster University (Canadà)) ;
Kolesar, Richard (McMaster University (Canadà)) ;
Teixidor Serra, Jordi (Hospital Universitari Vall d'Hebron) ;
Tomas-Hernandez, Jordi (Hospital Universitari Vall d'Hebron) ;
McGillion, Michael (McMaster University (Canadà)) ;
Shanthanna, Harsha (McMaster University (Canadà)) ;
Moppett, Iain (University of Nottingham) ;
Vincent, Jessica (Population Health Research Institute) ;
Pettit, Shirley (Population Health Research Institute) ;
Harvey, Valerie (Population Health Research Institute) ;
Gauthier, Leslie (Hamilton Health Sciences) ;
Alvarado, Kim (McMaster University (Canadà)) ;
Devereaux, P. J (McMaster University (Canadà)) ;
Universitat Autònoma de Barcelona
Introduction Annually, millions of adults suffer hip fractures. The mortality rate post a hip fracture is 7%-10% at 30 days and 10%-20% at 90 days. Observational data suggest that early surgery can improve these outcomes in hip fracture patients. [...]
2019 - 10.1136/bmjopen-2018-028537
BMJ open, Vol. 9 Núm. 4 (january 2019) , p. e028537
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