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7 p, 638.1 KB |
Associations of hypomagnesemia in patients seeking a first treatment of alcohol use disorder
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Hernandez-Rubio, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Girona Biomedical Research Institute. Clinical Pharmacology Department) ;
Barbier-Torres, Lucía (Cedars-Sinai Medical Center) ;
Blanes, Rafael (Hospital Universitari Son Dureta (Palma de Mallorca, Balears)) ;
Miquel, Laia (Universitat de Barcelona) ;
Torrens, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rubio, Gabriel (Universidad Complutense de Madrid) ;
Bolao, Ferran (Universitat de Barcelona) ;
Zuluaga Cruz, Andrea Paola (Clinical Pharmacology Department) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodríguez de Fonseca, Fernando (Instituto de Investigación Biomédica de Málaga) ;
Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
INTRODUCTION: Hypomagnesemia (hypoMg) has not yet been extensively studied in alcohol use disorder (AUD) . We hypothesize that chronic, excessive alcohol consumption favors oxidative stress and pro-inflammatory alterations that may be exacerbated by hypoMg. [...]
2023 -  10.1016/j.drugalcdep.2023.109822
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15 p, 1.9 MB |
Clinical and genetic spectra of autosomal dominant tubulointerstitial kidney disease due to mutations in UMOD and MUC1
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Olinger, Eric (Newcastle University) ;
Hofmann, Patrick (Hospital Uster) ;
Kidd, Kendrah (Charles University) ;
Dufour, Inès (Division of Nephrology. Cliniques Universitaires Saint-Luc) ;
Belge, Hendrica (Institute of Pathology and Genetics) ;
Schaeffer, Céline (San Raffaele Scientific Institute) ;
Kipp, Anne (University of Zurich) ;
Bonny, Olivier (Lausanne University Hospital) ;
Deltas, Constantinos (University of Cyprus) ;
Demoulin, Nathalie (Université catholique de Louvain) ;
Fehr, Thomas (Cantonal Hospital Graubuenden) ;
Fuster, Daniel G. (Inselspital Bern University Hospital) ;
Gale, Daniel (University College of London) ;
Goffin, Eric (Université catholique de Louvain) ;
Hodaňová, Kateřina (Charles University) ;
Huynh-Do, Uyen (Inselspital Bern University Hospital) ;
Kistler, Andreas (Cantonal Hospital Frauenfeld) ;
Morelle, Johann (Université catholique de Louvain) ;
Papagregoriou, Gregory (University of Cyprus) ;
Pirson, Yves (Cliniques Universitaires Saint-Luc) ;
Sandford, Richard (Cambridge Biomedical Campus) ;
Sayer, John (Newcastle University) ;
Torra Balcells, Roser (Institut d'Investigació Biomèdica Sant Pau) ;
Venzin, Christina (Hospital Davos) ;
Venzin, Reto (Cantonal Hospital Graubuenden) ;
Vogt, Bruno (Inselspital Bern University Hospital) ;
Živná, Martina (Charles University) ;
Greka, Anna (Massachusetts Institute of Technology) ;
Dahan, Karin (Institute of Pathology and Genetics) ;
Rampoldi, Luca (San Raffaele Scientific Institute) ;
Kmoch, Stanislav (Charles University) ;
Bleyer, Anthony (Charles University) ;
Devuyst, Olivier (Cliniques Universitaires Saint-Luc) ;
Universitat Autònoma de Barcelona
Autosomal dominant tubulointerstitial kidney disease (ADTKD) is an increasingly recognized cause of end-stage kidney disease, primarily due to mutations in UMOD and MUC1. The lack of clinical recognition and the small size of cohorts have slowed the understanding of disease ontology and development of diagnostic algorithms. [...]
2020 - 10.1016/j.kint.2020.04.038
Kidney International, Vol. 98 Núm. 3 (september 2020) , p. 717-731
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9 p, 1.0 MB |
Cytotoxic NK cells phenotype and activated lymphocytes are the main characteristics of patients with alcohol-associated liver disease
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Zurera Egea, Coral (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zuluaga Blanco, Yenny Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
T cells, natural killer (NK) and NKT cells have opposing actions in the development of alcohol-associated liver fibrosis. We aimed to evaluate the phenotype of NK cells, NKT cells and activated T cells in patients with alcohol use disorder (AUD) according to the presence of advanced liver fibrosis (ALF). [...]
2023 - 10.1007/s10238-023-01121-1
Clinical and Experimental Medicine, Vol. 23, Num. 7 (november 2023) , p. 3539-3547
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17 p, 1.4 MB |
Immune Response and Effects of COVID-19 Vaccination in Patients with Lung Cancer-COVID Lung Vaccine Study
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Hernandez, Ainhoa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Boigues Pons, Marc (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Felip, Eudald (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cucurull, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Notario, Lucia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pous, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Torres, Pere (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Benitez, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodriguez, Marina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quirant, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Romeo, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fuster, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Moran, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina)
During the SARS-CoV-2 pandemic, lung cancer patients have been considered an especially vulnerable population and have been prioritized for vaccination. However, several aspects (degree of immunity, potential interaction with active anticancer therapy, safety, and tolerability of the vaccines) remained unclear. [...]
2022 - 10.3390/cancers15010137
Cancers, Vol. 15, Num. 1 (January 2022) , art. 137
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7 p, 116.6 KB |
Bases biològiques de la patologia [101883]
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Villoria Ferrer, Albert ;
Monreal Bosch, Manuel ;
Puig Domingo, Manuel ;
Tor Aguilera, Jordi ;
Alijotas-Reig, Jaume ;
Muga, Roberto ;
Altimir Losada, Salvador ;
Martinez Rubio, Antoni ;
Domingo, Christian ;
Oristrell Salva, Joaquín ;
Caixàs i Pedragós, Maria Assumpta ;
Calvet, Joan ;
Almirall Daly, Jaume ;
Pena Perez, Xoel ;
Romeu Fontanals, Joan ;
Olivé Marqués, Alejandro ;
Santemases Ejarque, Javier ;
Dávalos, Antoni ;
Tudela Hita, Pedro ;
Casademont i Pou, Jordi ;
Núñez Aragón, Raquel ;
Pacho Pacho, Cristina ;
Zuluaga Blanco, Yenny Paola ;
López Loureiro, Yéssica ;
Feijoo Masso, Carlos ;
Sigüenza Bonete, Patricia ;
Marí, Begoña ;
Fuster, Daniel ;
Lopez Nuñez, Juan Jose ;
Universitat Autònoma de Barcelona.
Facultat de Biociències
L'assignatura es programa a tercer curs del Grau a les Unitats Docents Hospitalàries, un cop s'han assolit els coneixements bàsics sobre l'estructura i funció del cos humà. El seu objectiu és l'estudi de la fisiopatologia orientada a la comprensió dels aspectes generals i bàsics de les malalties. [...]
The subject is scheduled in the third year of the Degree at the Hospital Teaching Units, once basic knowledge about the structure and function of the human body has been achieved. Its objective is the study of physiopathology oriented to the understanding of the general and basic aspects of diseases. [...]
La asignatura se programa en el tercer curso del Grado en las Unidades Docentes Hospitalarias, una vez se han alcanzado los conocimientos básicos sobre la estructura y función del cuerpo humano. Su objetivo es el estudio de la fisiopatología orientada a la comprensión de los aspectos generales y básicos de las enfermedades. [...]
2022-23
Grau en Ciències Biomèdiques [832]
3 documentos
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10 p, 795.8 KB |
Low CD4/CD8 ratio is associated with increased morbidity and mortality in late and non-late presenters : results from a multicentre cohort study, 2004-2018
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Domínguez-Domínguez, Lourdes (Hospital Universitario 12 de Octubre (Madrid)) ;
Rava, Marta (CIBER de Enfermedades Infecciosas) ;
Bisbal, Otilia (Hospital Universitario 12 de Octubre (Madrid)) ;
Lopez-Cortés, Luis (Instituto de Biomedicina de Sevilla) ;
Portilla, Joaquín (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Podzamczer, Daniel (Hospital Universitari de Bellvitge) ;
Olalla, Julián (Hospital Costa del Sol (Marbella)) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rubio, Rafael (CIBER de Enfermedades Infecciosas) ;
Jarrín, Inmaculada (CIBER de Enfermedades Infecciosas) ;
Iribarren, José Antonio (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Moreno, Santiago (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Universitat Autònoma de Barcelona
To study whether the association between the CD4/CD8 ratio variation over time and the development of clinical outcomes vary in late presenters (CD4 count < 350/µL or AIDS event at enrolment) or advanced presenters (CD4 count < 200/µL or AIDS event at enrolment). [...]
2022 - 10.1186/s12879-022-07352-z
BMC Infectious diseases, Vol. 22 (april 2022) , art. 379
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19 p, 765.0 KB |
Abuse Potential of Cathinones in Humans : a Systematic Review
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Poyatos, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Torres, Adrian (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Papaseit, Esther (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez-Mañá, Clara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hladun, Olga (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Núñez-Montero, Melani (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
de la Rosa, Georgina (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Torrens, Marta (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fuster, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Muga, Roberto (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Farre, Magi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Introduction and objective: Assessing the abuse potential of new substances with central nervous system activity is essential for preventing possible risks of misuse and addiction. The same methodology is recommended for the evaluation of the abuse potential of recreational drugs. [...]
2022 - 10.3390/jcm11041004
Journal of clinical medicine, Vol. 11 Núm. 4 (february 2022) , p. 1004
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7 p, 427.0 KB |
Unhealthy Alcohol Use, HIV Infection and Risk of Liver Fibrosis in Drug Users with Hepatitis C
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Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Tor Aguilera, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez, Elisenda (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Muñoz, Alvaro (Johns Hopkins University. Bloomberg School of Public Health) ;
Universitat Autònoma de Barcelona
To analyze alcohol use, clinical data and laboratory parameters that may affect FIB-4, an index for measuring liver fibrosis, in HCV-monoinfected and HCV/HIV-coinfected drug users. Patients admitted for substance abuse treatment between 1994 and 2006 were studied. [...]
2012 - 10.1371/journal.pone.0046810
PloS one, Vol. 7 (october 2012)
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