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34 p, 677.3 KB |
Identification of Trypanosoma cruzi Discrete Typing Units (DTUs) in Latin-American migrants in Barcelona (Spain)
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Abras, Alba (Universitat de Girona. Departament de Biologia) ;
Gállego Culleré, M. (Montserrat) (Institut de Salut Global de Barcelona) ;
Muñoz-Batet, Carmen (Institut d'Investigació Biomèdica Sant Pau) ;
Juiz, Natalia A. (Laboratorio de Biología Molecular de la Enfermedad de Chagas) ;
Ramírez, Juan Carlos (Laboratorio de Biología Molecular de la Enfermedad de Chagas) ;
Cura, Carolina I. (Laboratorio de Biología Molecular de la Enfermedad de Chagas) ;
Tebar, Silvia (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Fernández-Arévalo, Anna (Institut d'Investigació Biomèdica Sant Pau) ;
Pinazo, María-Jesus (Institut de Salut Global de Barcelona) ;
de la Torre, Leonardo (Institut de Salut Global de Barcelona) ;
Posada, Elizabeth (Institut de Salut Global de Barcelona) ;
Navarro Risueño, Ferran (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Espinal, Paula (Institut d'Investigació Biomèdica Sant Pau) ;
Ballart, Cristina (Institut de Salut Global de Barcelona) ;
Portús, Montserrat (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Gascon, Joaquim (Institut de Salut Global de Barcelona) ;
Schijman, Alejandro G. (Laboratorio de Biología Molecular de la Enfermedad de Chagas)
Trypanosoma cruzi, the causative agent of Chagas disease, is divided into six Discrete Typing Units (DTUs): TcI-TcVI. We aimed to identify T. cruzi DTUs in Latin-American migrants in the Barcelona area (Spain) and to assess different molecular typing approaches for the characterization of T. [...]
2017 -  10.1016/j.parint.2016.12.003
Parasitology International, Vol. 66, Issue 2 (April 2017) , p. 83-88
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9 p, 597.2 KB |
Usefulness of Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry in the Characterization of Leishmania Strains Causing Tegumentary Leishmaniasis in Bolivia versus hsp70 Gene Sequencing
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Torrico, Mary Cruz (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Fernández-Arévalo, Anna (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Ballart, Cristina (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Solano, Marco (Universidad Mayor de San Simón) ;
Rojas, Ernesto (Universidad Mayor de San Simón) ;
Abras, Alba (Universitat de Girona. Departament de Biologia) ;
Gonzales, Fabiola (Universidad Mayor de San Simón) ;
Arnau, Albert (Universitat de Girona. Departament de Biologia) ;
Tebar, Silvia (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient) ;
Llovet, Teresa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Lozano, Daniel (Universidad Mayor de San Simón) ;
Ariza-Vioque, Eva (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gascon, Joaquim (Institut de Salut Global de Barcelona) ;
Picado, Albert (Institut de Salut Global de Barcelona) ;
Torrico, Faustino (Universidad Mayor de San Simón) ;
Muñoz, Carmen (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Gállego Culleré, M. (Montserrat) (Universitat de Barcelona. Departament de Biologia, Sanitat i Medi Ambient)
Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) is a proteomic technique with proven efficiency in the identification of microorganisms, such as bacteria, fungi, and parasites. [...]
2023 - 10.1128/spectrum.03477-22
Microbiology Spectrum, Vol. 11, Issue 1 (February 2023) , art. e03477-22
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15 p, 1.6 MB |
First external quality assurance program for bloodstream Real-Time PCR monitoring of treatment response in clinical trials of Chagas disease
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Ramírez, Juan C. (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres") ;
Parrado, Rudy (Universidad Mayor de San Simón) ;
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
de la Barra, Anabelle (Universidad Mayor de San Simón, Cochabamba, Bolivia) ;
Rodríguez, Marcelo (Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán") ;
Villarroel, Sandro (Universidad Mayor de San Simón) ;
Irazu, Lucía (Instituto Nacional de Enfermedades Infecciosas "Dr. Carlos G. Malbrán") ;
Alonso-Vega, Cristina (Drugs for Neglected Diseases initiative) ;
Alves, Fabiana (Drugs for Neglected Diseases initiative (Suïssa)) ;
Curto, María A. (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres") ;
García, Lineth (Universidad Mayor de San Simón) ;
Ortiz, Lourdes (Universidad Autónoma Juan Misael Saracho) ;
Torrico, Faustino (Fundación CEADES) ;
Gascon, Joaquim (Barcelona Institute for Global Health (ISGlobal)) ;
Flevaud, Laurence (Médecins Sans Frontières Operational Center Barcelona-Athens) ;
Molina Romero, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribeiro, Isabela (Drugs for Neglected Diseases initiative (Suïssa)) ;
Schijman, Alejandro G. (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres") ;
Universitat Autònoma de Barcelona
Real-Time PCR (qPCR) testing is recommended as both a diagnostic and outcome measurement of etiological treatment in clinical practice and clinical trials of Chagas disease (CD), but no external quality assurance (EQA) program provides performance assessment of the assays in use. [...]
2017 - 10.1371/journal.pone.0188550
PloS one, Vol. 12 (november 2017)
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14 p, 1.6 MB |
Introducing automation to the molecular diagnosis of Trypanosoma cruzi infection : A comparative study of sample treatments, DNA extraction methods and real-time PCR assays
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Abras, Alba (Universitat de Girona. Departament de Biologia) ;
Ballart, Cristina (Barcelona Institute for Global Health (ISGlobal)) ;
Llovet, Teresa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Roig, Carme (Institut d'Investigació Biomèdica Sant Pau) ;
Gutiérrez, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Tebar, Silvia (Barcelona Institute for Global Health (ISGlobal)) ;
Berenguer, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Pinazo, María-Jesús (Barcelona Institute for Global Health (ISGlobal)) ;
Posada, Elizabeth (Barcelona Institute for Global Health (ISGlobal)) ;
Gascon, Joaquim (Barcelona Institute for Global Health (ISGlobal)) ;
Schijman, Alejandro G. (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular) ;
Gállego Culleré, M. (Montserrat) (Barcelona Institute for Global Health (ISGlobal)) ;
Muñoz, Carmen (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Polymerase chain reaction (PCR) has become a useful tool for the diagnosis of Trypanosoma cruzi infection. The development of automated DNA extraction methodologies and PCR systems is an important step toward the standardization of protocols in routine diagnosis. [...]
2018 - 10.1371/journal.pone.0195738
PloS one, Vol. 13, Issue 4 (April 2018) , art. e0195738
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18 p, 2.3 MB |
Fixed vs adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy : A systematic review and meta-analysis
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Ciapponi, Agustín (Centro de Investigaciones Epidemiológicas y Salud Pública (Argentina)) ;
Barreira, Fabiana (Drugs for Neglected Diseases initiative (DND i), Río de Janeiro, Brazil) ;
Perelli, Lucas (Centro Cochrane Argentino) ;
Bardach, Ariel (Centro de Investigaciones Epidemiológicas y Salud Pública (Argentina)) ;
Gascon, Joaquim (Hospital Clínic i Provincial de Barcelona) ;
Molina Romero, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Morillo, Carlos A (McMaster University (Canadà)) ;
Prado, Nilda (Instituto Nacional de Parasitología Dr. M Fatala Chaben (Argentina)) ;
Riarte, Adelina (Instituto Nacional de Parasitología Dr. M Fatala Chaben (Argentina)) ;
Torrico, Faustino (Universidad Mayor de San Simón (Bolivia)) ;
Ribeiro, Isabela (Drugs for Neglected Diseases initiative (Suïssa)) ;
Villar, Juan Carlos (Universidad Autónoma de Bucaramanga) ;
Sosa-Estani, Sergio (Drugs for Neglected Diseases initiative (Brasil)) ;
Universitat Autònoma de Barcelona
Chagas disease is a neglected disease that remains a public health threat, particularly in Latin America. The most important treatment options are nitroimidazole derivatives, such as nifurtimox and benznidazole (BZN). [...]
2020 - 10.1371/journal.pntd.0008529
PLoS neglected tropical diseases, Vol. 14 (august 2020)
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14 p, 572.6 KB |
European expert network on rare communicable diseases and other rare diseases linked to mobility and globalisation focused on health care provision (EURaDMoG) : a feasibility study
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Requena-Méndez, Ana (Karolinska Institutet (Estocolm, Suècia). Department of Medicine) ;
Bisoffi, Zeno (Università di Verona. Dipartimento di Diagnostica e Sanità Pubblica) ;
Vives Corrons, Juan Luís (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Gascon, Joaquim (Barcelona Institute for Global Health (ISGlobal)) ;
Plasència, A.. (Barcelona Institute for Global Health (ISGlobal)) ;
Universitat Autònoma de Barcelona
Introduction: In the current mobility and globalization context, there is a growing need to identify potential changes on the pattern of diseases in the European Union (EU)/European Economic Area (EEA) and provide accurate diagnosis and treatment for the population. [...]
2020 - 10.1186/s13023-020-01534-1
Orphanet Journal of Rare Diseases, Vol. 15 Núm. 1 (january 2020) , p. 291
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16 p, 2.8 MB |
Anti-Trypanosoma cruzi Activity of Metabolism Modifier Compounds
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Martinez-Peinado, Nieves (Institut de Salut Global de Barcelona) ;
Cortés Serra, Núria (Institut de Salut Global de Barcelona) ;
Sherman, Julian (New York University School of Medicine. Department of Microbiology) ;
Rodriguez, Ana (New York University School of Medicine. Department of Microbiology) ;
Gascon, Joaquim (Barcelona Institute for Global Health (ISGlobal)) ;
Alberola, Jordi (Alberola i Domingo) (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Pinazo, Maria-Jesus (Institut de Salut Global de Barcelona) ;
Rodríguez-Cortés, Alhelí (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Alonso-Padilla, Julio (Institut de Salut Global de Barcelona) ;
Martori Muntsant, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and affects over 6 million people worldwide. Development of new drugs to treat this disease remains a priority since those currently available have variable efficacy and frequent adverse effects, especially during the long regimens required for treating the chronic stage of the disease. [...]
2021 - 10.3390/ijms22020688
International journal of molecular sciences, Vol. 22 Núm. 2 (2021) , p. 688
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16 p, 409.2 KB |
Epidemiology of congenital chagas disease 6 years after implementation of a public health surveillance system, Catalonia, 2010 to 2015
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Basile, Luca (Servei Català de la Salut) ;
Ciruela, Pilar (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Requena-Méndez, Ana (Barcelona Institute for Global Health (ISGlobal)) ;
José Vidal, M. A. (Servei Català de la Salut) ;
Dopico, Eva (Laboratori Clínic de l'Hospitalet. Hospitalet de Llobregat) ;
Martín-Nalda, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron) ;
Gascon, Joaquim (Barcelona Institute for Global Health (ISGlobal)) ;
Jané i Checa, Mireia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Universitat Autònoma de Barcelona
Background: Chagas disease is endemic in Latin America and affects 8 million people worldwide. In 2010, Catalonia introduced systematic public health surveillance to detect and treat congenital Chagas disease. [...]
2019 - 10.2807/1560-7917.ES.2019.24.26.19-00011
Eurosurveillance, Vol. 24 Núm. 26 (2019) , p. 1900011
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