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Cardiopoietic cell therapy for advanced ischaemic heart failure : results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial
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Bartunek, Jozef (Cardiovascular Center, Onze-Lieve-Vrouwziekenhuis OLV Hospital, Moorselbaan 164, Aalst, B-9300, Aalst, Belgium) ;
Terzic, Andre (Mayo Clinic, Center for Regenerative Medicine, Department of Cardiovascular Diseases, 200 First Street SW, Rochester, Minnesota 550905, USA) ;
Davison, Beth A. (Momentum Research, Inc, Durham, NC, USA) ;
Filippatos, Gerasimos S. (University General Hospital Attikon (Haidari, Grècia)) ;
Radovanovic, Slavica (University Hospital Center Bezanijska Kosa, Belgrade, Serbia) ;
Beleslin, Branko (University of Belgrade. Cardiology Clinic) ;
Merkely, Bela (Semmelweis University. Heart and Vascular Center) ;
Musialek, Piotr (Jagiellonian University Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow, Poland) ;
Wojakowski, Wojciech (Third Division of Cardiology, Medical University of Silesia, Katowice, Poland) ;
Andreka, Peter (Gottsegen Gyorgy Hungarian Institute of Cardiology, Budapest, Hungary) ;
Horvath, Ivan G. (Heart Institute, University of Pécs, Pécs, Hungary) ;
Katz, Amos (Department of Cardiology, Barzilai Medical Center, Israel Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel) ;
Dolatabadi, Dariouch (Division of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium) ;
El Nakadi, Badih (Division of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium) ;
Arandjelovic, Aleksandra (Cardiology Department, Clinical Hospital Zvezdara, Belgrade, Serbia) ;
Edes, Istvan (Department of Cardiology, University of Debrecen, Debrecen, Hungary) ;
Seferovic, Petar M. (University of Belgrade School of Medicine, Belgrade University Medical Center, Belgrade, Serbia) ;
Obradovic, Slobodan (Clinic of Emergency Medicine, Military Medical Academy, School of Medicine, University of Defense, Belgrade, Serbia) ;
Vanderheyden, Marc (Cardiovascular Center, Onze-Lieve-Vrouwziekenhuis OLV Hospital, Moorselbaan 164, Aalst, B-9300, Aalst, Belgium) ;
Jagic, Nikola (Clinical Center Kragujevac, Kragujevac, Serbia) ;
Petrov, Ivo (Department of Cardiology, Angiology, and Electrophysiology, City Clinic Heart and Vascular Institute, Sofia University, Sofia, Bulgaria) ;
Atar, Shaul (Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel) ;
Halabi, Majdi (Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel) ;
Gelev, Valeri L. (Department of Cardiology, Angiology, and Electrophysiology, City Clinic Heart and Vascular Institute, Sofia University, Sofia, Bulgaria) ;
Shochat, Michael K. (Heart Institute, Hillel Yaffe Medical Center, Hadera, Rappaport School of Medicine, Haifa, Israel, Technion) ;
Kasprzak, Jaroslaw D. (Medical University of Lodz) ;
Sanz-Ruiz, Ricardo (Hospital General Universitario Gregorio Marañón) ;
Heyndrickx, Guy R. (Cardiovascular Center, Onze-Lieve-Vrouwziekenhuis OLV Hospital, Moorselbaan 164, Aalst, B-9300, Aalst, Belgium) ;
Nyolczas, Noémi (Medical Centre, Hungarian Defense Forces, Budapest, Hungary) ;
Legrand, Victor (Department of Cardiology, Centre Hospitalier Universitaire de Liège, Liège, Belgium) ;
Guédès, Antoine (Department of Cardiology, Universite Catholique de Louvain, CHU UcL Namur, Yvoir, Belgium) ;
Heyse, Alex (Department of Cardiology, AZ Glorieux, Ronse, Belgium) ;
Moccetti, Tiziano (Cardiocentro Ticino, Lugano, Switzerland) ;
Fernandez Aviles, Francesc (Hospital General Universitario Gregorio Marañón) ;
Jimenez-Quevedo, Pilar (Hospital Clínico San Carlos (Madrid)) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernandez-Garcia, Jose Maria (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Ribichini, Flavio (Department of Cardiology, University of Verona, Italy) ;
Gruchala, Marcin (Department of Cardiology, Medical University of Gdansk, Gdansk, Poland) ;
Waldman, Scott A. (Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA) ;
Teerlink, John R. (School of Medicine, University of California San Francisco and Section of Cardiology, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA) ;
Gersh, Bernard J. (Mayo Clinic, Center for Regenerative Medicine, Department of Cardiovascular Diseases, 200 First Street SW, Rochester, Minnesota 550905, USA) ;
Povsic, Thomas J. (Duke Clinical Research Institute and Duke Medicine, Durham, NC, USA) ;
Henry, Timothy D. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
Metra, Marco (Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University and Spedali Civili, Brescia, Italy) ;
Hajjar, Roger J. (Mount Sinai School of Medicine, New York, NY, USA) ;
Tendera, Michal (Third Division of Cardiology, Medical University of Silesia, Katowice, Poland) ;
Behfar, Atta (Mayo Clinic, Center for Regenerative Medicine, Department of Cardiovascular Diseases, 200 First Street SW, Rochester, Minnesota 550905, USA) ;
Alexandre, Bertrand (Celyad, Mont Saint Guibert, Belgium) ;
Seron, Aymeric (Celyad, Mont Saint Guibert, Belgium) ;
Stough, Wendy Gattis (Departments of Clinical Research and Pharmacy Practice, Campbell University College of Pharmacy and Health Sciences, Cary, NC, USA) ;
Sherman, Warren (Celyad, Mont Saint Guibert, Belgium) ;
Cotter, Gad (Momentum Research, Inc, Durham, NC, USA) ;
Wijns, William (The Lambe Institute for Translational Medicine and Curam, National University of Ireland Galway and Saolta University Healthcare Group, Galway, Ireland) ;
Universitat Autònoma de Barcelona
Cardiopoietic cells, produced through cardiogenic conditioning of patients' mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial aimed to validate cardiopoiesis-based biotherapy in a larger heart failure cohort. [...]
2016 -  10.1093/eurheartj/ehw543
European heart journal, Vol. 38 (december 2016) , p. 648-660
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Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations
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Blanco, Gonzalo (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Baliakas, Panagiotis (Uppsala University. Department of Immunology, Genetics and Pathology) ;
Athanasiadou, Anastasia (G. Papanicolaou Hospital (Thessaloniki, Greece)) ;
García-Malo, MaDolores (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Collado, Rosa (Hospital General Universitario de Valencia) ;
Xochelli, Aliki (Institute of Applied Biosciences, CERTH, Thessaloniki, Greece) ;
Rodríguez-Rivera, María (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ortega, Margarita (Hospital Universitari Vall d'Hebron) ;
Calasanz, M.J (Universidad de Navarra. Departamento de Bioquímica y Genética) ;
Luño, Elisa (Hospital Universitario Central de Asturias) ;
Vargas, MªTeresa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Grau Cat, Javier (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martínez-Laperche, Carolina (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Valiente, Alberto (Complejo Hospitalario de Navarra) ;
Cervera, José (Hospital Universitari i Politècnic La Fe (València)) ;
Anagnostopoulos, Achilles (George Papanicolaou General Hospital (Tessalònia, Grècia)) ;
Gimeno, Eva (Hospital del Mar (Barcelona, Catalunya)) ;
Abella Monreal, Eugenia (Hospital del Mar (Barcelona, Catalunya)) ;
Stalika, Evangelia (Institute of Applied Biosciences, CERTH, Thessaloniki, Greece) ;
Hernández Rivas, Jesús María (Hospital Universitario de Salamanca) ;
Ortuño, Francisco José (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Robles, Diego (Servicio de Hematología, Hospital Txagorritxu, Vitoria, Spain) ;
Ferrer, Ana (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ivars, David (Hospital General Universitario de Valencia) ;
González, Marcos (Hospital Universitario de Salamanca. Centro de Investigación del Cáncer) ;
Bosch José, Francesc Xavier 1947- (Hospital Universitari Vall d'Hebron) ;
Abrisqueta, Pau (Hospital Universitari Vall d'Hebron) ;
Stamatopoulos, Kostas (Institute of Applied Biosciences, CERTH, Thessaloniki, Greece) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53 abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p (8p−) and gains of 8q (8q+) have been suggested to aggravate the outcome of patients with TP53 abs. [...]
2016 - 10.18632/oncotarget.13106
Oncotarget, Vol. 7 (november 2016) , p. 80916-80924
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