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15 p, 1.0 MB R2d2 drives selfish sweeps in the house mouse / Didion, John P. (Carolina Center for Genome Science) ; Morgan, Andrew P. (Carolina Center for Genome Science) ; Yadgary, Liran (Carolina Center for Genome Science) ; Bell, Timothy A. (Carolina Center for Genome Science) ; McMullan, Rachel C. (Carolina Center for Genome Science) ; Ortiz de Solorzano, Lydia (Carolina Center for Genome Science) ; Britton-Davidian, Janice (Université de Montpellier. Institut des Sciences de l'Evolution) ; Bult, Carol J. (The Jackson Laboratory) ; Campbell, Karl J. (The University of Queensland. School of Geography, Planning & Environmental Management) ; Castiglia, Riccardo (Università degli studi di Roma "La Sapienza") ; Ching, Yung-Hao (Tzu Chi University. Department of Molecular Biology and Human Genetics) ; Chunco, Amanda J. (Elon University. Department of Environmental Studies) ; Crowley, James J. (The University of North Carolina at Chapel Hill. Department of Genetics) ; Chesler, Elissa J. (The Jackson Laboratory) ; Förster, Daniel W. (Leibniz-Institut für Zoo- und Wildtierforschung. Department of Evolutionary Genetics) ; French, John E. (National Institute of Environmental Health Sciences. National Toxicology Program) ; Gabriel, Sofia I. (Universidade de Lisboa. Department of Animal Biology) ; Gatti, Daniel M. (The Jackson Laboratory) ; Garland, Theodore (University of California, Riverside. Department of Biology) ; Giagia-Athanasopoulou, Eva B. (University of Patras. Department of Biology) ; Giménez, Mabel D. (Universidad Nacional de Misiones (Argentina). Instituto de Biología Subtropical) ; Grize, Sofia A. (Universität Zürich. Institute of Evolutionary Biology and Environmental Studies) ; Gündüz, İslam (University of Ondokuz Mayis. Department of Biology, Faculty of Arts and Sciences) ; Holmes, Andrew (National Institutes of Health. National Institute on Alcohol Abuse and Alcoholism) ; Hauffe, Heidi C. (Fondazione Edmund Mach. Department of Biodiversity and Molecular Ecology, Research and Innovation Centre) ; Herman, Jeremy S. (National Museums Scotland. Department of Natural Sciences) ; Holt, James M. (The University of North Carolina at Chapel Hill. Department of Computer Science) ; Hua, Kunjie (The University of North Carolina at Chapel Hill. Department of Genetics) ; Jolley, Wesley J. (Island Conservation (Santa Cruz, Califòrnia)) ; Lindholm, Anna K. (Universität Zürich. Institute of Evolutionary Biology and Environmental Studies) ; López-Fuster, María J. (Universitat de Barcelona. Facultat de Biologia) ; Mitsainas, George (University of Patras. Department of Biology) ; da Luz Mathias, Maria (Universidade de Lisboa. Department of Animal Biology) ; McMillan, Leonard (The University of North Carolina at Chapel Hill. Department of Computer Science) ; Ramalhinho, Maria da Graça Morgado (Universidade de Lisboa. Department of Animal Biology) ; Rehermann, Barbara (National Institute of Diabetes and Digestive and Kidney Diseases (Bethesda, Estats Units d'Amèrica)) ; Rosshart, Stephan P. (National Institute of Diabetes and Digestive and Kidney Diseases (Bethesda, Estats Units d'Amèrica)) ; Searle, Jeremy B. (Cornell University. Department of Ecology and Evolutionary Biology) ; Shiao, Meng-Shin (Mahidol University. Faculty of Medicine) ; Solano, Emanuela (Università degli studi di Roma "La Sapienza") ; Svenson, Karen L. (The Jackson Laboratory) ; Thomas-Laemont, Patricia (Elon University. Department of Environmental Studies) ; Threadgill, David W. (Texas A&M University. Department of Molecular and Cellular Medicine) ; Ventura Queija, Jacinto (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Weinstock, George M. (Jackson Laboratory for Genomic Medicine) ; Pomp, Daniel (Carolina Center for Genome Science) ; Churchill, Gary A. (The Jackson Laboratory) ; Pardo-Manuel de Villena, Fernando (Carolina Center for Genome Science)
A selective sweep is the result of strong positive selection driving newly occurring or standing genetic variants to fixation, and can dramatically alter the pattern and distribution of allelic diversity in a population. [...]
2016 - 10.1093/molbev/msw036
Molecular biology and evolution, Vol. 33, issue 6 (June 2016) , p. 1381-1395  
Registro completo - Creative Commons
2.
23 p, 4.0 MB MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria / Dalla Rosa, Ilaria (MRC Mill Hill Laboratory, London, United Kingdom) ; Cámara, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Durigon, Romina (MRC Mill Hill Laboratory) ; Moss, Chloe F. (MRC Mill Hill Laboratory) ; Vidoni, Sara (MRC Mitochondrial Biology Unit, Wellcome Trust-MRC Building) ; Akman, Gokhan (MRC Mill Hill Laboratory) ; Hunt, Lilian (MRC Mill Hill Laboratory) ; Johnson, Mark A. (MRC Mitochondrial Biology Unit, Wellcome Trust-MRC Building) ; Grocott, Sarah (Mitochondrial Genetics Group, Nuffield Department of Obstetrics and Gynaecology, Women's Centre, The John Radcliffe Hospital, Oxford, United Kingdom) ; Wang, Liya (Department of Anatomy, Physiology and Biochemistry, The Swedish University of Agricultural Sciences, Biomedical Center) ; Thorburn, David R. (Murdoch Childrens Research Institute and University of Melbourne Department of Paediatrics, Royal Children's Hospital) ; Hirano, Michio (Department of Neurology, Columbia University Medical Center, New York, New York, United States of America) ; Poulton, Joanna (Mitochondrial Genetics Group, Nuffield Department of Obstetrics and Gynaecology, Women's Centre, The John Radcliffe Hospital) ; Taylor, Robert W. (Wellcome Trust Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, The Medical School, Newcastle upon Tyne) ; Elgar, Greg (MRC Mill Hill Laboratory) ; Martí, Ramon A. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Voshol, Peter (Institute of Metabolic Science, University of Cambridge) ; Holt, Ian J. (MRC Mill Hill Laboratory, London) ; Spinazzola, Antonella (MRC Mill Hill Laboratory) ; Universitat Autònoma de Barcelona
MPV17 is a mitochondrial inner membrane protein whose dysfunction causes mitochondrial DNA abnormalities and disease by an unknown mechanism. Perturbations of deoxynucleoside triphosphate (dNTP) pools are a recognized cause of mitochondrial genomic instability; therefore, we determined DNA copy number and dNTP levels in mitochondria of two models of MPV17 deficiency. [...]
2016 - 10.1371/journal.pgen.1005779
PLoS Genetics, Vol. 12 (january 2016)  
Registro completo - Creative Commons

Vea también: autores con nombres similares
2 Holt, J.K.L.
1 Holt, James M.
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