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9 p, 319.8 KB |
Limiting Cumulative HIV Viremia Copy-Years by Early Treatment Reduces Risk of AIDS and Death
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Olson, Ashley D. (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Walker, A. Sarah (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Suthar, Amitabh B. (South African Centre for Epidemiological Modelling and Analysis, University of Stellenbosch, South Africa) ;
Sabin, Caroline A. (Department of Infection and Population Health, University College London (UCL), London, United Kingdom) ;
Bucher, Heiner (University Hospital Basel (Basilea, Suïssa)) ;
Jarrín, Inmaculada (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Moreno, Santiago (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Porter, Kholoud (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Ford, Deborah (Medical Research Council Clinical Trials Unit, University College London, London, United Kingdom) ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. Viremia copy-years (VCY), a time-updated measure of cumulative HIV exposure, predicts AIDS/death; although its utility in deciding when to start combination antiretroviral therapy (cART) remains unclear. [...]
2016 -  10.1097/QAI.0000000000001029
Journal of acquired immune deficiency syndromes (1999), Vol. 73 (august 2016) , p. 100-108
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8 p, 283.7 KB |
When to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries : A Prospective Observational Study
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Caniglia, Ellen C. (Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA) ;
Sabin, Caroline A. (University College London, London, United Kingdom) ;
Robins, James M. (Department of Biostatistics, Harvard T.H. Chan School of Public Health) ;
Logan, Roger (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Cain, Lauren E. (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Abgrall, Sophie (Assistance Publique-Hopitaux de Paris (AP-HP), Hopital Antoine Béclère, Service de Médecine Interne) ;
Mugavero, Michael J. (University of Alabama at Birmingham) ;
Hernandez-Diaz, Sonia (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Meyer, Laurence (Université Paris Sud, INSERM CESP U1018, and AP-HP, Hopital de Bicêtre, Service de Santé Publique) ;
Seng, Remonie (Université Paris Sud, INSERM CESP U1018, and AP-HP, Hopital de Bicêtre, Service de Santé Publique) ;
Drozd, Daniel R. (Division of Allergy and Infectious Diseases, School of Medicine, University of Washington) ;
Seage, George R. (Department of Epidemiology, Harvard T.H. Chan School of Public Health) ;
Bonnet, Fabrice (Bordeaux University, ISPED, INSERM U897 CHU de Bordeaux) ;
Dabis, Francois (INSERM U897, Centre Inserm Epidémiologie et Biostatistique, Université de Bordeaux, and Department of Internal Medicine, Bordeaux University Hospital) ;
Moore, Richard R. (School of Medicine, Johns Hopkins University, Baltimore, MD) ;
Reiss, Peter (Stichting HIV Monitoring, Amsterdam, Netherlands; Academic Medical Center, Department of Global Health and Division of Infectious Diseases, University of Amsterdam, and Amsterdam Institute for Global Health and Development) ;
van Sighem, Ard (Stichting HIV Monitoring, Amsterdam, Netherlands) ;
Mathews, William C. (Internal Medicine, Johns Hopkins University) ;
Del Amo, Julia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Moreno, Santiago (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Deeks, Steven G. (Positive Health Program, San Francisco General Hospital) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Boswell, Stephen L. (Fenway Health) ;
Ferrer, Elena (Institut d'Investigació Biomèdica de Bellvitge) ;
Eron, Joseph J. (Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill) ;
Napravnik, Sonia (Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill) ;
Jose, Sophie (University College London) ;
Phillips, Andrew (University College London, London, United Kingdom) ;
Olson, Ashley (Medical Research Council Clinical Trials Unit, University College London) ;
Justice, Amy C. (VA Connecticut Healthcare System) ;
Tate, Janet P. (VA Connecticut Healthcare System) ;
Bucher, Heiner (University Hospital Basel (Basilea, Suïssa)) ;
Egger, Matthias (University of Bern, Institute for Social and Preventive Medicine, Bern, Switzerland) ;
Touloumi, Giota (Department of Hygiene, Epidemiology and Medical Statistics, Athens University Medical School) ;
Sterne, Jonathan A. (School of Social and Community Medicine, University of Bristol) ;
Costagliola, Dominique (Institute Pierre Louis d'Épidémiologie et de Santé Publique) ;
Saag, Michael (Department of Medicine, University of Alabama at Birmingham) ;
Hernán, Miguel A. (Department of Medicine, University of Alabama at Birmingham) ;
Universitat Autònoma de Barcelona
Supplemental Digital Content is Available in the Text. To illustrate an approach to compare CD4 cell count and HIV-RNA monitoring strategies in HIV-positive individuals on antiretroviral therapy (ART). [...]
2016 - 10.1097/QAI.0000000000000956
Journal of acquired immune deficiency syndromes (1999), Vol. 72 (may 2016) , p. 214-221
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