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1.
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9 p, 894.5 KB |
Indirect competitive immunoassay for the detection of fungicide Thiabendazole in whole orange samples by Surface Plasmon Resonance
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Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ;
Belenguer, José (Ainia Centro Tecnológico (Valencia)) ;
Gomez-Montes, Silvia (Institut Català de Nanociència i Nanotecnologia) ;
Miralles, Javier (Ainia Centro Tecnológico (Valencia)) ;
Escuela, Alfonso M. (Universidad de Las Palmas de Gran Canaria) ;
Montoya, Angel (Universitat Politècnica de València) ;
Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)
A highly sensitive and specific SPR-based competitive immunoassay for the detection of Thiabendazole (TBZ) has been developed. An indirect format where a TBZ-protein conjugate is immobilized onto gold surfaces has been selected. [...]
2012 -  10.1039/c2an36094b
Analyst, Vol. 137, Issue 23 (October 2012) , p. 5659-5665
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2.
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46 p, 703.3 KB |
Integrated optical devices for lab-on-a-chip biosensing applications
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Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ;
Alvarez, Mar (Institut Català de Nanociència i Nanotecnologia) ;
Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)
The application of portable, easy-to-use and highly sensitive lab-on-a-chip biosensing devices for real-time diagnosis could offer significant advantages over current analytical methods. Integrated optics-based biosensors have become the most suitable technology for lab-on-chip integration due to their ability for miniaturization, their extreme sensitivity, robustness, reliability, and their potential for multiplexing and mass production at low cost. [...]
2012 - 10.1002/lpor.201100025
Laser & photonics reviews, Vol. 6, Issue 4 (July 2012) , p. 463-487
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3.
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7 p, 3.0 MB |
Integration of Metal-Organic Polyhedra onto a Nanophotonic Sensor for Real-Time Detection of Nitrogenous Organic Pollutants in Water
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Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ;
Hernández-López, Laura (Universitat Autònoma de Barcelona. Departament de Química) ;
Gomez, Leyre (Institut Català de Nanociència i Nanotecnologia) ;
Carné-Sánchez, Arnau (Universitat Autònoma de Barcelona. Departament de Química) ;
von Baeckmann, Cornelia (Universitat Autònoma de Barcelona. Departament de Química) ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia) ;
Maspoch Comamala, Daniel (Universitat Autònoma de Barcelona. Departament de Química)
The grave health and environmental consequences of water pollution demand new tools, including new sensing technologies, for the immediate detection of contaminants in situ. Herein, we report the integration of metal-organic cages or polyhedra (MOCs/MOPs) within a nanophotonic sensor for the rapid, direct, and real-time detection of small (<500 Da) pollutant molecules in water. [...]
2023 - 10.1021/acsami.3c07213
ACS applied materials & interfaces, Vol. 15, Issue 33 (August 2023) , p. 39523-39529
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9 p, 4.8 MB |
Biomimetic nanoplasmonic sensor for rapid evaluation of neutralizing SARS-CoV-2 monoclonal antibodies as antiviral therapy
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Batool, Razia (Institut Català de Nanociència i Nanotecnologia) ;
Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ;
Colavita, Francesca (National Institute for Infectious Disease "L. Spallanzani") ;
Fabeni, Lavinia (National Institute for Infectious Disease "L. Spallanzani") ;
Matusali, Giulia (National Institute for Infectious Disease "L. Spallanzani") ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
Monoclonal antibody (mAb) therapy is one of the most promising immunotherapies that have shown the potential to prevent or neutralize the effects of COVID-19 in patients at very early stages, with a few formulations recently approved by the European and American medicine agencies. [...]
2023 - 10.1016/j.bios.2023.115137
Biosensors & bioelectronics, Vol. 226 (April 2023) , art. 115137
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5.
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6.6 MB |
Nanophotonic point-of-care biosensors for innovative clinical diagnosis of respiratory diseases
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Calvo Lozano, Olalla ;
Lechuga, Laura M, dir. ;
Villaverde Corrales, Antonio, dir.
Els mètodes convencionals per al diagnòstic de les malalties respiratòries es basen principalment en les proves clíniques per imatge. Complementar aquesta anàlisi amb una avaluació molecular pot proporcionar un diagnòstic més adequat i complet. [...]
Los métodos convencionales para el diagnóstico de las enfermedades respiratorias se basan principalmente en las pruebas clínicas por imagen. Complementar este análisis con una evaluación molecular puede proporcionar un diagnóstico más adecuado y completo. [...]
The conventional methods for the diagnosis of respiratory diseases rely mainly on the clinical evidence by imaging. Complementing such analysis with a molecular evaluation can provide a more suitable and exhaustive diagnosis. [...]
2022
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12 p, 4.9 MB |
Rapid and direct quantification of the SARS-CoV-2 virus with an ultrasensitive nanobody-based photonic nanosensor
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Ruiz Vega, Gisela (Institut Català de Nanociència i Nanotecnologia) ;
Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ;
Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ;
Ramirez Priego, Patricia (Institut Català de Nanociència i Nanotecnologia) ;
Pazos, Martalu D. (Institut Català de Nanociència i Nanotecnologia) ;
Noriega, María A. (Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología) ;
Margolles, Yago (Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología) ;
Francés-Gómez, Clara (Universitat de València. Institut de Biologia Integrativa de Sistemes) ;
Geller, Ron (Universitat de València. Institut de Biologia Integrativa de Sistemes) ;
Matusali, Giulia (Istituto Nazionale Malattie Infettive Lazzaro Spallanzani IRCCS) ;
Colavita, Francesca (Istituto Nazionale Malattie Infettive Lazzaro Spallanzani IRCCS) ;
Caro, Antonino di (Istituto Nazionale Malattie Infettive Lazzaro Spallanzani IRCCS) ;
Casasnovas, José M. (Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología) ;
Fernández, Luis Angel (Consejo Superior de Investigaciones Científicas. Centro Nacional de Biotecnología) ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
The coronavirus (CoV) disease 2019 (COVID-19) is expected to become endemic in the coming years, meaning that the worldwide society shall be prepared to routinely manage the highly contagious respiratory SARS-CoV-2. [...]
2022 - 10.1039/D2SD00082B
Sensors & Diagnostics, Vol. 1, issue 5 (Sep. 2022) , p. 983-993
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7.
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48 p, 1.4 MB |
Coating bioactive microcapsules with tannic acid enhances the phenotype of the encapsulated pluripotent stem cells
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Choi, Daheui (Mayo Clinic, Department of Physiology and Biomedical Engineering) ;
Gwon, Kihak (Mayo Clinic. Department of Physiology and Biomedical Engineering) ;
Hong, Hye Jin (Mayo Clinic. Department of Physiology and Biomedical Engineering) ;
Baskaran, Harihara (Case Western Reserve University. Department of Chemical and Biomolecular Engineering) ;
Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ;
Gonzalez-Suarez, Alan M. (Mayo Clinic. Department of Physiology and Biomedical Engineering) ;
Park, Kyungtae (Yonsei University. Department of Chemical and Biomolecular Engineering) ;
De Hoyos-Vega, Jose M. (Mayo Clinic. Department of Physiology and Biomedical Engineering) ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia) ;
Hong, Jinkee (Yonsei University. Department of Chemical and Biomolecular Engineerin) ;
Stybayeva, Gulnaz (Mayo Clinic. Department of Physiology and Biomedical Engineering) ;
Revzin, Alexander (Mayo Clinic. Department of Physiology and Biomedical Engineering)
Human pluripotent stem cells (hPSCs) may be differentiated into any adult cell type and therefore hold incredible promise for cell therapeutics and disease modeling. There is increasing interest in three-dimensional (3D) hPSC culture because of improved differentiation outcomes and potential for scale up. [...]
2022 - 10.1021/acsami.2c06783
ACS applied materials & interfaces, Vol. 14, issue 23 (June 2022) , p. 27274-27286
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8.
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7 p, 2.4 MB |
One-step and real-time detection of microRNA-21 in human samples for lung cancer biosensing diagnosis
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Calvo Lozano, Olalla (Institut Català de Nanociència i Nanotecnologia) ;
García Aparicio, Pablo (Institut Català de Nanociència i Nanotecnologia) ;
Raduly, Lajos-Zsolt (Iuliu Hatieganu University of Medicine and Pharmacy) ;
Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia) ;
Berindan Neagoe, Ioana (Iuliu Hatieganu University of Medicine and Pharmacy) ;
Ferracin, Manuela (Università di Bologna. Dipartimento di Scienze Mediche e Chirurgiche) ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)
The rapid diagnosis of cancer, especially in its early stages, is crucial for on-time medical treatment and for increasing the patient survival rate. Lung cancer shows the highest mortality rate and the lowest 5-year survival rate due to the late diagnosis in advanced cancer stages. [...]
2022 - 10.1021/acs.analchem.2c02895
Analytical chemistry, Vol. 94, issue 42 (Oct. 2022) , p. 14659-14665
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10.
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15 p, 11.2 MB |
Integrated optical bimodal waveguide biosensors : principles and applications
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Torrijos-Morán, Luis (Universitat Politècnica de València. Nanophotonics Technology Center) ;
Diego Lisboa, Bárbara (Institut Català de Nanociència i Nanotecnologia) ;
Soler Aznar, Maria (Institut Català de Nanociència i Nanotecnologia) ;
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia) ;
García-Rupérez, J. (Nanophotonics Technology Center. Universitat Politècnica de València)
Integrated optical biosensors have become one of the most compelling technologies for the achievement of highly sensitive, multianalyte, portable and easy to use point-of-care (POC) devices with tremendous impact in healthcare and environmental protection, among other application fields. [...]
2022 - 10.1016/j.rio.2022.100285
Results in Optics, Vol. 9 (Dec. 2022) , art. 100285
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