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DNA methylation and general psychopathology in childhood : an epigenome-wide meta-analysis from the PACE consortium
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Rijlaarsdam, Jolien (Erasmus MC University Medical Center Rotterdam) ;
Cosin-Tomas, Marta (Universitat Pompeu Fabra) ;
Schellhas, Laura (University Medical Center Hamburg) ;
Abrishamcar, Sarina (Emory University) ;
Malmberg, Anni (University of Helsinki) ;
Neumann, Alexander (VIB Center for Molecular Neurology) ;
Felix, Janine F. (Erasmus MC University Medical Center Rotterdam) ;
Sunyer, Jordi (Centro de investigación biomédica en red en epidemiología y salud pública (ciberesp)) ;
Gutzkow, Kristine B. (Norwegian Institute of Public Health (NIPH)) ;
Grazuleviciene, Regina (Vytautas Magnus University) ;
Wright, John (Bradford Teaching Hospitals NHS Foundation Trust) ;
Kampouri, Mariza (University of Crete) ;
Zar, Heather J. (University of Cape Town) ;
Stein, Dan J. (University of Cape Town) ;
Heinonen, Kati (University of Helsinki) ;
Räikkönen, Katri (University of Helsinki) ;
Lahti, Jari (University of Helsinki) ;
Hüls, Anke (Emory University) ;
Caramaschi, Doretta (University of Exeter) ;
Alemany, Sílvia (Hospital Universitari Vall d'Hebron) ;
Cecil, Charlotte A. M. (Leiden University Medical Center) ;
Universitat Autònoma de Barcelona
The general psychopathology factor (GPF) has been proposed as a way to capture variance shared between psychiatric symptoms. Despite a growing body of evidence showing both genetic and environmental influences on GPF, the biological mechanisms underlying these influences remain unclear. [...]
2022 -  10.1038/s41380-022-01871-6
Molecular psychiatry, Vol. 28 (november 2022) , p. 1128-1136
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16 p, 2.6 MB |
Brain aging in major depressive disorder : results from the ENIGMA major depressive disorder working group
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Han, L.K.M. (Vrije Universiteit & GGZinGeest) ;
Dinga, Richard (Radboud University) ;
Hahn, Tim (University of Münster) ;
Ching, Christopher R. K. (University of Southern California) ;
Eyler, Lisa (University of California San Diego) ;
Aftanas, Lybomir (Novosibirsk State University) ;
Aghajani, Moji (Vrije Universiteit & GGZinGeest) ;
Aleman, André (University of Groningen) ;
Baune, Bernhard T. (The University of Melbourne) ;
Berger, Klaus (University of Münster) ;
Brak, Ivan (Novosibirsk State University) ;
Filho, Geraldo Busatto (Universidade de Sao Paulo) ;
Carballedo, Angela (North Dublin Mental Health Services) ;
Connolly, Colm G. (Florida State University) ;
Couvy-Duchesne, Baptiste (University of Queensland) ;
Cullen, Kathryn R. (University of Minnesota Medical School) ;
Dannlowski, Udo (University of Münster) ;
Davey, Christopher (The University of Melbourne) ;
Dima, Danai (King's College London) ;
Souza-Duran, Fabio Luis (Universidade de Sao Paulo) ;
Enneking, Verena (University of Münster) ;
Filimonova, Elena (Cognitive & Translational Neuroscience) ;
Frenzel, Stefan (University Medicine Greifswald) ;
Frodl, Thomas (German Center for Neurodegenerative Diseases (DZNE)) ;
Fu, Cynthia H.Y. (University of East London) ;
Godlewska, Beata (University of Oxford) ;
Gotlib, Ian H. (Stanford University) ;
Grabe, Hans J. (German Center for Neurodegenerative Diseases) ;
Groenewold, Nynke A. (University of Cape Town) ;
Grotegerd, Dominik (University of Münster) ;
Gruber, Oliver (University of Heidelberg) ;
Hall, Geoffrey B. (McMaster University (Canadà)) ;
Harrison, Ben (The University of Melbourne & Melbourne Health) ;
Hatton, Sean N. (University of California San Diego) ;
Hermesdorf, Marco (University of Münster) ;
Hickie, Ian B. (University of Sydney) ;
Ho, Tiffany C. (Standord University) ;
Hosten, Norbert (University Medicine Greifswald) ;
Jansen, Andreas (Philipps-University Marburg) ;
Kähler, Claas (University of Münster) ;
Kircher, Tilo (Philipps-University Marburg) ;
Klimes-Dougan, Bonnie (University of Minnesota) ;
Krämer, Bernd (University of Heidelberg) ;
Krug, Axel (University of Bonn) ;
Lagopoulos, Jim (University of the Sunshine Coast QLD) ;
Leenings, Ramona (University of Münster) ;
MacMaster, Frank (Addictions and Mental Health Strategic Clinical Network) ;
MacQueen, Glenda (University of Calgary) ;
McIntosh, Andrew M. (University of Edinburgh) ;
McLellan, Quinn (University of Alberta) ;
McMahon, Katie (Queensland University of Technology) ;
Medland, Sarah Elizabeth (QIMR Berghofer Medical Research Instititute) ;
Mueller, Bryon (University of Minnesota Medical School) ;
Mwangi, Benson (DepartThe University of Texas Health Science Center at Houston) ;
Osipov, Evgeny (Novosibirsk State University) ;
Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau) ;
Pozzi, Elena (The University of Melbourne & Melbourne Health) ;
Reneman, Liesbeth (Amsterdam UMC. University Medical Center) ;
Repple, Jonathan (University of Münster) ;
Gomes Penteado Rosa, Pedro (Universidade de Sao Paulo) ;
Sacchet, Matthew D. (Harvard Medical School) ;
Sämann, Philipp G. (Max Planck Institute of Psychiatry) ;
Schnell, Knut (Asklepios Fachklinikum Göttingen) ;
Schrantee, Anouk (Amsterdam UMC. University Medical Center) ;
Simulionyte, Egle (McMaster University (Canadà)) ;
Soares, Jair C. (The University of Texas Health Science Center at Houston) ;
Sommer, Jens (University of Minnesota) ;
Stein, Dan J. (University of Cape Town) ;
Steinsträter, Olaf (University Medicine Greifswald) ;
Strike, Lachlan (University of Queensland) ;
Thomopoulos, Sophia I. (University of Southern California) ;
van Tol, Marie-José (University of Groningen) ;
Veer, Ilya M. (DiCharité-Universitätsmedizin Berlin) ;
Vermeiren, Robert R. J. M. (Leiden University) ;
Walter, Henrik (Charité - Universitätsmedizin Berlin) ;
van der Wee, Nic J. A. (Leiden University Medical Center) ;
van der Werff, Steven J. A. (Leiden University Medical Center) ;
Whalley, Heather (University of Edinburgh) ;
Winter, Nils Ralf (University of Münster) ;
Wittfeld, Katharina (German Center of Neurodegenerative Diseases (DZNE) Site Rostock/Greifswald) ;
Wright, Margaret J (University of Queensland) ;
Wu, Mon-Ju (The University of Texas Health Science Center at Houston) ;
Völzke, Henry (University Medicine Greifswald) ;
Yang, Tony T. (UCSF School of Medicine) ;
Zannias, Vasileios (University of Edinburgh) ;
de Zubicaray, Greig (Queensland University of Technology) ;
Zunta-Soares, Giovana B. (The University of Texas Health Science Center at Houston) ;
Abé, Christoph (Karolinska Institutet (Estocolm, Suècia)) ;
Alda, Martin (Dalhousie University) ;
Andreassen, Ole A. (Oslo University Hospital (Oslo, Noruega)) ;
Bøen, Erlend (Oslo University Hospital (Oslo, Noruega)) ;
Bonnin, Caterina del Mar (Hospital Clínic i Provincial de Barcelona) ;
Canales-Rodriguez, Erick Jorge (FIDMAG Germanes Hospitalàries Research Foundation) ;
Cannon, Dara (National University of Ireland Galway) ;
Caseras, Xavier (Cardiff University) ;
Chaim-Avancini, Tiffany M. (Universidade de Sao Paulo) ;
Elvsåshagen, Torbjørn (Oslo University Hospital (Oslo, Noruega)) ;
Favre, Pauline (Hôpitaux Universitaires Mondor) ;
Foley, Sonya (Cardiff University) ;
Fullerton, Janice M. (University of New South Wales) ;
Goikolea Alberdi, Jose Manuel (Hospital Clínic i Provincial de Barcelona) ;
Haarman, Bartholomeus C. M. (University of Groningen) ;
Hajek, Tomas (Dalhousie University) ;
Henry, Chantal (Université de Paris) ;
Houenou, Josselin (Hôpitaux Universitaires Mondor) ;
Howells, Fleur M. (University of Cape Town) ;
Ingvar, Martin (Karolinska Institutet (Estocolm, Suècia)) ;
Kuplicki, Rayus (Laureate Institute for Brain Research) ;
Lafer, B. (University of Sao Paulo (FMUSP)) ;
Landén, Mikael (Karolinska Institutet (Estocolm, Suècia)) ;
Machado-Vieira, Rodrigo (University of Sao Paulo (FMUSP)) ;
Malt, Ulrik (Oslo University Hospital (Oslo, Noruega)) ;
McDonald, Colm (National University of Ireland Galway) ;
Mitchell, Philip B. (Prince of Wales Hospital (Australia)) ;
Nabulsi, Leila (National University of Ireland Galway) ;
Otaduy, Maria C. G. (Universidade de Sao Paulo) ;
Overs, Bronwyn J. (Neuroscience Research Australia) ;
Polosan, Mircea (Grenoble Institut des Neurosciences) ;
Pomarol-Clotet, Edith (FIDMAG Germanes Hospitalàries Research Foundation) ;
Radua, Joaquim (Hospital Clínic i Provincial de Barcelona) ;
Rive, Maria M. (Amsterdam UMC. University Medical Center) ;
Roberts, Gloria (Prince of Wales Hospital (Australia)) ;
Ruhe, Henricus G. (Radboud University Medical Center) ;
Salvador, Raymond (FIDMAG Germanes Hospitalàries Research Foundation) ;
Sarró, Salvador (FIDMAG Germanes Hospitalàries Research Foundation) ;
Satterthwaite, Theodore D (University of Pennsylvannia Perelman School of Medicine) ;
Savitz, Jonathan (The University of Tulsa) ;
Schene, Aart H. (Radboud University Medical Center) ;
Schofield, Peter R. (University of New South Wales) ;
Serpa, Mauricio (Universidade de Sao Paulo) ;
Sim, Kang (National University of Singapore) ;
Soeiro-de-Souza, M.G. (University of Sao Paulo (FMUSP)) ;
Sutherland, Ashley N. (University of California San Diego) ;
Temmingh, Henk S. (Valkenberg Psychiatric Hospital) ;
Timmons, Garrett M. (University of California San Diego) ;
Uhlmann, Anne (University of Cape Town) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Wolf, Daniel H. (University of Pennsylvannia Perelman School of Medicine) ;
Zanetti, Marcus Vinicius (Hospital Sírio-Libanês) ;
Jahanshad, Neda (University of Southern California) ;
Thompson, Paul M. (University of Southern California) ;
Veltman, Dick J. (Vrije Universiteit & GGZinGeest) ;
Penninx, Brenda WJH. (Vrije Universiteit & GGZinGeest) ;
Marquand, Andre F. (Radboud University Medical Centre) ;
Cole, James Howard (University College London) ;
Schmaal, Lianne (The University of Melbourne) ;
Universitat Autònoma de Barcelona
Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced brain aging in adult MDD patients, and whether this process is associated with clinical characteristics in a large multicenter international dataset. [...]
2021 - 10.1038/s41380-020-0754-0
Molecular psychiatry, Vol. 26 Núm. 9 (september 2021) , p. 5124-5139
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14 p, 1.3 MB |
A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials
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Sforzini, Luca (King's College London) ;
Worrell, Courtney (King's College London) ;
Kose, Melisa (King's College London) ;
Anderson, Ian M. (The University of Manchester and Manchester Academic Health Sciences Centre) ;
Aouizerate, Bruno (University of Bordeaux) ;
Arolt, Volker (University of Münster) ;
Bauer, Michael (University Hospital Carl Gustav Carus) ;
Baune, Bernhard T. (The University of Melbourne) ;
Cleare, Anthony J. (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Cowen, Philip J. (University of Oxford) ;
Dinan, Timothy G. (University College Cork) ;
Fagiolini, Andrea (University of Siena) ;
Ferrier, I. Nicol (Newcastle University) ;
Hegerl, Ulrich (Goethe University) ;
Krystal, Andrew D. (Duke University School of Medicine) ;
Leboyer, Marion (Université Paris Est Creteil (UPEC)) ;
McAllister-Williams, R. Hamish (Cumbria, Northumberland, Tyne and Wear NHS Foundation Trust) ;
McIntyre, Roger S. (Brain and Cognition Discovery Foundation) ;
Meyer-Lindenberg, Andreas (Heidelberg University) ;
Miller, Andrew H. (Emory University School of Medicine) ;
Nemeroff, Charles B. (University of Texas at Austin) ;
Normann, Claus (Medical Center - University of Freiburg) ;
Nutt, David (Imperial College) ;
Pallanti, Stefano (University of Florence) ;
Pani, Luca (VeraSci) ;
Penninx, Brenda W. J. H. (Vrije Universiteit and GGZinGeest) ;
Schatzberg, Alan F. (Stanford University) ;
Shelton, Richard C. (University of Alabama at Birmingham) ;
Yatham, Lakshmi N. (University of British Columbia) ;
Young, Allan H. (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Zahn, Roland (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Aislaitner, Georgios (Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM)) ;
Butlen-Ducuing, Florence (European Medicines Agency) ;
Fletcher, Christine (Biostatistics, GlaxoSmithKline) ;
Haberkamp, Marion (Federal Institute for Drugs and Medical Devices (Bundesinstitut für Arzneimittel und Medizinprodukte, BfArM)) ;
Laughren, Thomas (Laughren Psychopharm Consulting) ;
Mäntylä, Fanni-Laura (GAMIAN-Europe (Global Alliance of Mental Illness Advocacy Networks-Europe)) ;
Schruers, Koen (University of Leuven) ;
Thomson, Andrew (European Medicines Agency) ;
Arteaga-Henríquez, Gara (Hospital Universitari Vall d'Hebron) ;
Benedetti, Francesco (IRCCS Scientific Institute Ospedale San Raffaele) ;
Cash-Gibson, Lucinda (Hospital Universitari Vall d'Hebron) ;
Chae, Woo Ri (Charité - Universitätsmedizin Berlin) ;
De Smedt, Heidi (Janssen Research & Development) ;
Gold, Stefan M. (University Medical Center Hamburg-Eppendorf) ;
Hoogendijk, Witte J. G. (Erasmus University Medical Centre) ;
Mondragón, Valeria Jordán (Medical Director Neuroscience for Region Europe at Novartis Pharma) ;
Maron, Eduard (West Tallinn Central Hospital) ;
Martynowicz, Jadwiga (Janssen Research & Development) ;
Melloni, Elisa (IRCCS Scientific Institute Ospedale San Raffaele) ;
Otte, Christian (Charité - Universitätsmedizin Berlin) ;
Perez-Fuentes, Gabriela (Hospital Universitari Vall d'Hebron) ;
Poletti, Sara (IRCCS Scientific Institute Ospedale San Raffaele) ;
Schmidt, Mark E. (Janssen Pharmaceutica NV) ;
van de Ketterij, Edwin (European Infrastructure for Translational Medicine (EATRIS)) ;
Woo, Katherine (Janssen Research & Development) ;
Flossbach, Yanina (Novartis Pharma AG) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Savitz, Adam J. (Department of Neuroscience) ;
Pariante, Carmine M (National Institute for Health Research Mental Health Biomedical Research Centre) ;
Universitat Autònoma de Barcelona
Criteria for treatment-resistant depression (TRD) and partially responsive depression (PRD) as subtypes of major depressive disorder (MDD) are not unequivocally defined. In the present document we used a Delphi-method-based consensus approach to define TRD and PRD and to serve as operational criteria for future clinical studies, especially if conducted for regulatory purposes. [...]
2021 - 10.1038/s41380-021-01381-x
Molecular psychiatry, Vol. 27 (december 2021) , p. 1286-1299
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10 p, 1.6 MB |
Association of cortical microstructure with amyloid-β and tau : impact on cognitive decline, neurodegeneration, and clinical progression in older adults
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Rodriguez-Vieitez, Elena (Karolinska Institutet (Estocolm, Suècia)) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Sepulcre, Jorge (Gordon Center for Medical Imaging) ;
Lois, Cristina (Gordon Center for Medical Imaging) ;
Hanseeuw, Bernard (Université Catholique de Louvain) ;
Vilaplana, Eduard (Institut d'Investigació Biomèdica Sant Pau) ;
Schultz, Aaron P. (Athinoula A. Martinos Center for Biomedical Imaging) ;
Properzi, Michael J. (Harvard Medical School) ;
Scott, Matthew R. (Athinoula A. Martinos Center for Biomedical Imaging) ;
Amariglio, Rebecca (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Papp, Kathryn V. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Marshall, Gad A. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Johnson, Keith A. (Gordon Center for Medical Imaging) ;
Sperling, Reisa A. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Vannini, Patrizia (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Universitat Autònoma de Barcelona
Noninvasive biomarkers of early neuronal injury may help identify cognitively normal individuals at risk of developing Alzheimer's disease (AD). A recent diffusion-weighted imaging (DWI) method allows assessing cortical microstructure via cortical mean diffusivity (cMD), suggested to be more sensitive than macrostructural neurodegeneration. [...]
2021 - 10.1038/s41380-021-01290-z
Molecular psychiatry, Vol. 26 (september 2021) , p. 7813-7822
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15 p, 1.4 MB |
Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis
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Pollak, Thomas A. (King's College London. Department of Psychosis Studies) ;
Kempton, Matthew J. (King's College London. Department of Psychosis Studies) ;
Iyegbe, Conrad (King's College London. Department of Psychosis Studies) ;
Vincent, Angela (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Irani, Sarosh R. (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Coutinho, Ester (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Menassa, David A. (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Jacobson, Leslie (John Radcliffe Hospital (Oxford, Regne Unit)) ;
de Haan, Lieuwe (University of Amsterdam. Department Early Psychosis) ;
Ruhrmann, Stephan (University of Cologne. Department of Psychiatry and Psychotherapy) ;
Sachs, Gabriele (Medical University of Vienna. Department of Psychiatry and Psychotherapy) ;
Riecher-Rössler, Anita (University of Basel. Medical Faculty) ;
Krebs, Marie-Odile (University of Paris. Institut de Psychiatrie) ;
Amminger, Paul (University of Melbourne. Centre for Youth Mental Health) ;
Glenthøj, Birte (University of Copenhagen. Centre for Neuropsychiatric Schizophrenia Research & Centre for Clinical Intervention and Neuropsychiatric Schizophrenia Research) ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
van Os, Jim (Maastricht University Medical Centre. Department of Psychiatry and Neuropsychology) ;
Rutten, Bart P. F. (Maastricht University Medical Centre. Department of Psychiatry and Neuropsychology) ;
Bressan, Rodrigo Affonseca (Universidade Federal de São Paulo. Institute for Prevention of Mental Disorders) ;
van der Gaag, Mark (VU University. Department of Clinical Psychology) ;
Yolken, Robert (Johns Hopkins School of Medicine. Department of Pediatrics) ;
Hotopf, Matthew (King's College London. Department of Psychological Medicine) ;
Valmaggia, Lucia (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Stone, James (King's College London. Department of Psychosis Studies) ;
David, Anthony S. (King's College London. Department of Psychosis Studies) ;
McGuire, Philip (King's College London. Department of Psychosis Studies)
Serum neuronal autoantibodies, such as those to the NMDA receptor (NMDAR), are detectable in a subgroup of patients with psychotic disorders. It is not known if they are present before the onset of psychosis or whether they are associated with particular clinical features or outcomes. [...]
2020 - 10.1038/s41380-020-00899-w
Molecular psychiatry, Vol. 26 (october 2020) , p. 2590-2604
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10 p, 1.6 MB |
Structural brain imaging studies offer clues about the effects of the shared genetic etiology among neuropsychiatric disorders
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Radonjić, Nevena V. (SUNY Upstate Medical University. Department of Psychiatry) ;
Hess, Jonathan L. (SUNY Upstate Medical University. Departments of Psychiatry and of Neuroscience and Physiology) ;
Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Andreassen, Ole A. (University of Oslo. NORMENT-Institute of Clinical Medicine) ;
Buitelaar, Jan (Radboud University Medical Center. Department of Cognitive Neuroscience) ;
Ching, Christopher R. K. (University of Southern California. Imaging Genetics Center) ;
Franke, Barbara (Radboud University Medical Center. Department of Psychiatry) ;
Hoogman, Martine (Radboud University Medical Center. Department of Human Genetics) ;
Jahanshad, Neda (University of Southern California. Department of Neurology and Biomedical Engineering) ;
McDonald, Carrie (University of California. Department of Psychiatry) ;
Schmaal, Lianne (The National Centre of Excellence for Youth Mental Health. Orygen) ;
Sisodiya, Sanjay M. (Epilepsy Society. Chalfont Centre for Epilepsy) ;
Stein, Dan J. (University of Cape Town. Department of Psychiatry) ;
van den Heuvel, Odile A. (Amsterdam UMC. Department of Psychiatry) ;
van Erp, Theo G. M. (University of California Irvine. Center for the Neurobiology of Learning and Memory) ;
van Rooij, Daan (Radboud University Medical Center. Donders Centre for Cognitive Neuroimaging) ;
Veltman, Dick J. (Amsterdam UMC. Department of Psychiatry) ;
Thompson, Paul (University of Southern California. Neuro Imaging Institute for Neuroimaging and Informatics) ;
Faraone, Stephen V. (SUNY Upstate Medical University. Departments of Psychiatry and of Neuroscience and Physiology) ;
Universitat Autònoma de Barcelona
Genomewide association studies have found significant genetic correlations among many neuropsychiatric disorders. In contrast, we know much less about the degree to which structural brain alterations are similar among disorders and, if so, the degree to which such similarities have a genetic etiology. [...]
2021 - 10.1038/s41380-020-01002-z
Molecular psychiatry, Vol. 26 (june 2021) , p. 2101-2110
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11 p, 912.1 KB |
Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing
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Corominas Galbany, Jordi (Radboud University Medical Center) ;
Klein, Marieke (Radboud University Medical Center) ;
Zayats, Tetyana (University of Bergen) ;
Rivero, Olga (University of Würzburg) ;
Ziegler, Georg C. (University of Würzburg) ;
Pauper, Marc (Radboud University Medical Center) ;
Neveling, Kornelia (Radboud University Medical Center) ;
Poelmans, Geert (Radboud University Medical Center) ;
Jansch, Charline (University of Würzburg) ;
Svirin, Evgeniy (I.M. Sechenov First Moscow State Medical University) ;
Geissler, Julia (University Hospital of Würzburg) ;
Weber, Heike (University Hospital of Frankfurt (Alemanya)) ;
Reif, Andreas (University Hospital of Frankfurt (Alemanya)) ;
Arias-Vásquez, Alejandro (Radboud University Medical Center) ;
Galesloot, Tessel E. (Radboud University Medical Center) ;
Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ;
Buitelaar, Jan (Radboud University Medical Center) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hveem, Kristian (Norwegian University of Science and Technology) ;
Gabrielsen, Maiken Elvestad (Norwegian University of Science and Technology) ;
Hoffmann, Per (University of Basel) ;
Cichon, Sven (University Hospital Basel (Basilea, Suïssa)) ;
Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ;
Johansson, Stefan E (University of Bergen) ;
Jacob, Christian P. (University of Würzburg) ;
Romanos, Marcel (University Hospital of Würzburg) ;
Franke, Barbara (Radboud University Medical Center) ;
Lesch, Klaus-Peter (Maastricht University)
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with a complex genetic background, hampering identification of underlying genetic risk factors. We hypothesized that combining linkage analysis and whole-exome sequencing (WES) in multi-generation pedigrees with multiple affected individuals can point toward novel ADHD genes. [...]
2018 - 10.1038/s41380-018-0210-6
Molecular psychiatry, Vol. 25 (august 2018) , p. 2047-2057
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15 p, 2.0 MB |
White matter disturbances in major depressive disorder : a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group
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van Velzen, Laura S. (The University of Melbourne. Centre for Youth Mental Health) ;
Kelly, Sinead (Harvard Medical School) ;
Isaev, Dmitry (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ;
Aleman, André (University of Groningen. Cognitive Neuroscience Center, University Medical Center Groningen) ;
Aftanas, Lybomir (Novosibirsk State University. Department of Neuroscience) ;
Bauer, Jochen (University of Münster, Institute of Clinical Radiology, Münster, Germany) ;
Baune, Bernhard T. (The University of Melbourne, Melbourne. The Florey Institute of Neuroscience and Mental Heatlh) ;
Brak, Ivan (Novosibirsk State University. Lab. of Experimental & Translational Neuroscience) ;
Carballedo, Angela (North Dublin Mental Health Services, Dublin, Ireland) ;
Connolly, Colm G. (Florida State University. Department of Biomedical Sciences) ;
Couvy-Duchesne, Baptiste (The University of Queensland. Institute for Molecular Bioscience) ;
Cullen, Kathryn R. (The University of Minnesota. Department of Psychiatry and Behavioral Sciences) ;
Danilenko, Konstantin V. (FSSBI "Scientific Research Institute of Physiology & Basic Medicine", Laboratory of Affective, Cognitive & Translational Neuroscience, Novosibirsk, Russia) ;
Dannlowski, Udo (University of Münster. Department of Psychiatry) ;
Enneking, Verena (University of Münster. Department of Psychiatry) ;
Filimonova, Elena (FSSBI "Scientific Research Institute of Physiology & Basic Medicine", Laboratory of Affective, Cognitive & Translational Neuroscience, Novosibirsk, Russia) ;
Förster, Katharina (University of Münster. Department of Psychiatry) ;
Frodl, Thomas (German Center for Neurodegenerative Disease, Magdeburg, Germany) ;
Gotlib, Ian H. (Stanford University. Department of Psychology) ;
Groenewold, Nynke A. (Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands) ;
Grotegerd, Dominik (University of Münster. Department of Psychiatry) ;
Harris, Mathew A. (University of Edinburgh. Division of Psychiatry) ;
Hatton, Sean N. (University of Sydney. Youth Mental Health Team, Brain and Mind Centre) ;
Hawkins, Emma L. (University of Edinburgh. Division of Psychiatry) ;
Hickie, Ian B. (University of Sydney. Youth Mental Health Team, Brain and Mind Centre) ;
Ho, Tiffany C. (Stanford University. Department of Psychiatry & Behavioral Sciences) ;
Jansen, Andreas (University of Marburg. Department of Psychiatry) ;
Kircher, Tilo (University of Marburg. Department of Psychiatry) ;
Klimes-Dougan, Bonnie (The University of Minnesota. Department of Psychology) ;
Kochunov, Peter (University of Maryland School of Medicine. Maryland Psychiatric Research Center, Department of Psychiatry) ;
Krug, Axel (University of Marburg. Department of Psychiatry) ;
Lagopoulos, Jim (Sunshine Coast Mind and Neuroscience-Thompson Institute, Birtinya, QLD Australia) ;
Lee, Renick (Institute of Mental Health. Research Division) ;
Lett, Tristram A. (Humboldt-Universität zu Berlin) ;
Li, Meng (University of Magdeburg. Department of Neurology) ;
MacMaster, Frank P. (Strategic Clinical Network for Addictions and Mental Health, Calgary, Canada) ;
Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
McIntosh, Andrew M.. (University of Edinburgh. Centre for Cognitive Ageing and Cognitive Epidemiology) ;
McLellan, Quinn (Alberta Children's Hospital Research Institute) ;
Meinert, Susanne (University of Münster. Department of Psychiatry) ;
Nenadić, Igor (University of Marburg. Department of Psychiatry) ;
Osipov, Evgeny (Novosibirsk State University. Lab. of Experimental & Translational Neuroscience) ;
Penninx, Brenda W. J. H. (Department of Psychiatry, Amsterdam UMC, The Netherlands) ;
Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau) ;
Repple, Jonathan (University of Münster. Department of Psychiatry) ;
Roos, Annerine (Stellenbosch University. SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry) ;
Sacchet, Matthew D. (Harvard Medical School) ;
Sämann, Philipp G. (Max Planck Institute of Psychiatry) ;
Schnell, Knut (University of Heidelberg. Department of Psychiatry) ;
Shen, Xueyi (University of Edinburgh. Division of Psychiatry) ;
Sim, Kang (Nanyang Technological University. Lee Kong Chian School of Medicine) ;
Stein, Dan J. (SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, South Africa) ;
van Tol, Marie-José (University of Groningen. Cognitive Neuroscience Center) ;
Tomyshev, Alexander S. (Mental Health Research Center, Moscow, Russia) ;
Tozzi, Leonardo (Stanford University. Department of Psychiatry & Behavioral Sciences) ;
Veer, Ilya M. (Humboldt-Universität zu Berlin) ;
Vives-Gilabert, Yolanda (Universitat Politècnica de València. Instituto ITACA) ;
Walter, Henrik (Humboldt-Universität zu Berlin) ;
Walter, Martin (University of Tübingen. Department of Psychiatry and Psychotherapy) ;
van der Wee, Nic J. A. (Leiden University Medical Center. Department of Psychiatry) ;
van der Werff, Steven J. A. (Leiden University Medical Center. Department of Psychiatry) ;
Schreiner, Melinda Westlund (The University of Minnesota. Department of Psychology) ;
Whalley, Heather (University of Edinburgh. Division of Psychiatry) ;
Wright, Margaret J. (The University of Queensland. Centre for Advanced Imaging) ;
Yang, Tony T. (University of California. Department of Psychiatry) ;
Zhu, Alyssa (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ;
Veltman, Dick J. (Amsterdam Neuroscience) ;
Thompson, Paul M. (University of Southern California. Imaging Genetics Center) ;
Jahanshad, Neda (University of Southern California. Imaging Genetics Center) ;
Schmaal, Lianne (The University of Melbourne. Centre for Youth Mental Health) ;
Universitat Autònoma de Barcelona
Alterations in white matter (WM) microstructure have been implicated in the pathophysiology of major depressive disorder (MDD). However, previous findings have been inconsistent, partially due to low statistical power and the heterogeneity of depression. [...]
2019 - 10.1038/s41380-019-0477-2
Molecular psychiatry, Vol. 25 (august 2019) , p. 1511-1525
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Telling true from false : cannabis users show increased susceptibility to false memories
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Riba Serrano, Jordi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Valle, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Sampedro, Frederic (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Rodríguez Pujadas, A. (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez-Horta, S. (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Rodríguez Fornells, Antoni (Institució Catalana de Recerca i Estudis Avançats) ;
Universitat Autònoma de Barcelona
Previous studies on the neurocognitive impact of cannabis use have found working and declarative memory deficits that tend to normalize with abstinence. An unexplored aspect of cognitive function in chronic cannabis users is the ability to distinguish between veridical and illusory memories, a crucial aspect of reality monitoring that relies on adequate memory function and cognitive control. [...]
2015 - 10.1038/mp.2015.36
Molecular psychiatry, Vol. 20, Issue 6 (June 2015) , p. 772-777
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