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1.
22 p, 7.6 MB Pathways Related to NLRP3 Inflammasome Activation Induced by Gold Nanorods / Vandebriel, Rob J. (National Institute for Public Health & the Environment) ; Remy, Sylvie (Health Unit) ; Vermeulen, Jolanda P. (National Institute for Public Health & the Environment) ; Hurkmans, Evelien G. E. (National Institute for Public Health & the Environment) ; Kevenaar, Kirsten (National Institute for Public Health & the Environment) ; Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ; Pelaz, Beatriz (Universidade de Santiago de Compostela. Departamento de Química Inorgánica) ; Soliman, Mahmoud G. (University of Hamburg) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Parak, Wolfgang J. (University of Hamburg) ; Pennings, Jeroen L. A. (National Institute for Public Health & the Environment) ; Nelissen, Inge (Health Unit)
The widespread and increasing use of engineered nanomaterials (ENM) increases the risk of human exposure, generating concern that ENM may provoke adverse health effects. In this respect, their physicochemical characteristics are critical. [...]
2022 - 10.3390/ijms23105763
International journal of molecular sciences, Vol. 23, Issue 10 (May 2022) , art. 5763  
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2.
27 p, 1.5 MB Inter-laboratory comparison of nanoparticle size measurements using dynamic light scattering and differential centrifugal sedimentation / Langevin, Dominique (Centre National de la Recherche Scientifique (França)) ; Lozano, Omar (Escuela de Medicina y Ciencias de la Salud. Tecnologico de Monterrey. Cátedra de Cardiología y Medicina Vascular.) ; Salvati, Anna (University of Groningen. Groningen Research Institute of Pharmacy) ; Kestens, Vikram (European Commission. Joint Research Centre) ; Monopoli, Marco P. (University College Dublin. Centre for BioNano Interactions) ; Raspaud, Eric (Centre National de la Recherche Scientifique (França)) ; Mariot, Sandrine (Centre National de la Recherche Scientifique (França)) ; Salonen, Anniina (Centre National de la Recherche Scientifique (França)) ; Thomas, Steffi S. (University College Dublin. Centre for BioNano Interactions) ; Driessen, Marc D. (German Federal Institute for Risk Assessment. Department of Chemical and Product Safety) ; Haase, Andrea (German Federal Institute for Risk Assessment. Department of Chemical and Product Safety) ; Nelissen, Inge (Flemish Institute for Technological Research. Unit Environmental Risk and Health) ; Smisdom, Nick (Flemish Institute for Technological Research. Unit Environmental Risk and Health) ; Pompa, Pier Paolo (Istituto Italiano di Tecnologia) ; Maiorano, Gabriele (Istituto Italiano di Tecnologia) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Puchowicz, Dorota (Textile Research Institute. Scientific Department of Unconventional Technologies and Textiles) ; Stępnik, Maciej (Nofer Institute of Occupational Medicine. Department of Toxicology and Carcinogenesis) ; Suárez, Guillaume (Institut universitaire romand de Santé au Travail) ; Riediker, Michael (Nanyang Technological University. School of Materials Science & Engineering) ; Benetti, Federico (European Center for the Sustainable Impact of Nanotechnology) ; Mičetić, Ivan (European Center for the Sustainable Impact of Nanotechnology) ; Venturini, Marco (European Center for the Sustainable Impact of Nanotechnology) ; Kreyling, Wolfgang G. (German Research Center for Environmental Health. Helmholtz Centre Munich) ; van der Zande, Meike (Wageningen University & Research Centre) ; Bouwmeester, Hans (Wageningen University & Research Centre) ; Milani, Silvia (Ludwig-Maximilians-University. Soft condensed matter physics) ; Rädler, Joachim Oskar (Ludwig-Maximilians-University. Soft condensed matter physics) ; Mülhopt, Sonja (Karlsruhe Institute of Technology) ; Lynch, Iseult (University of Birmingham. School of Geography, Earth and Environmental Sciences.) ; Dawson, Kenneth A. (University College Dublin. Centre for BioNano Interactions)
Nanoparticle in vitro toxicity studies often report contradictory results with one main reason being insufficient material characterization. In particular the characterization of nanoparticles in biological media remains challenging. [...]
2018 - 10.1016/j.impact.2017.12.004
NanoImpact, Vol. 10 (April 2018) , p. 97-107  
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3.
21 p, 792.0 KB Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects / Oostingh, G. J. (Universität Salzburg. Fachbereich Molekulare Biologie) ; Casals, Eudald (Institut Català de Nanociència i Nanotecnologia) ; Italiani, Paola (Istituto Nanoscienze Consiglio Nazionale delle Ricerche. Istituto di Tecnologie Biomediche) ; Colognato, Renato (Italian Institute for Environmental Protection and Research) ; Stritzinger, René (Universität Salzburg. Fachbereich Molekulare Biologie) ; Ponti, Jessica (Italian Institute for Environmental Protection and Research) ; Pfaller, Tobias (Universität Salzburg. Fachbereich Molekulare Biologie) ; Kohl, Yvonne (Fraunhofer-Institut für Biomedizinische Technik) ; Ooms, Daniëla (Centre for Advanced R&D on Alternative Methods (Bèlgica)) ; Favilli, Flavia (Istituto Nanoscienze Consiglio Nazionale delle Ricerche. Istituto di Tecnologie Biomediche) ; Leppens, Hilde (Centre for Advanced R&D on Alternative Methods (Bèlgica)) ; Lucchesi, Davide (Istituto Nanoscienze Consiglio Nazionale delle Ricerche. Istituto di Tecnologie Biomediche) ; Rossi, François (Italian Institute for Environmental Protection and Research) ; Nelissen, Inge (Centre for Advanced R&D on Alternative Methods (Bèlgica)) ; Thielecke, Hagen (Fraunhofer-Institut für Biomedizinische Technik) ; Puntes, Víctor (Institució Catalana de Recerca i Estudis Avançats) ; Duschl, Albert (Universität Salzburg. Fachbereich Molekulare Biologie) ; Boraschi, Diana (Istituto Nanoscienze Consiglio Nazionale delle Ricerche. Istituto di Tecnologie Biomediche)
Background: With the increasing use of nanomaterials, the need for methods and assays to examine their immunosafety is becoming urgent, in particular for nanomaterials that are deliberately administered to human subjects (as in the case of nanomedicines). [...]
2011 - 10.1186/1743-8977-8-8
Particle and fibre toxicology, Vol. 8 (February 2011) , art. 8  
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4.
24 p, 7.8 MB Characterization of nanoparticle batch-to-batch variability / Mülhopt, Sonja (Karlsruhe Institute of Technology. Institute for Technical Chemistry (Germany)) ; Diabaté, Silvia (Karlsruhe Institute of Technology. Institute for Toxicology and Genetics (Germany)) ; Dilger, Marco (Karlsruhe Institute of Technology. Institute for Toxicology and Genetics (Germany)) ; Adelhelm, Christel (Karlsruhe Institute of Technology. Institute for Applied Materials (Germany)) ; Anderlohr, Christopher (Karlsruhe Institute of Technology. Institute for Technical Thermodynamics and Refrigeration (Germany)) ; Bergfeldt, Thomas (Karlsruhe Institute of Technology. Institute for Applied Materials (Germany)) ; Gómez de la Torre, Johan (Uppsala University. Department of Engineering Sciences (Sweden)) ; Jiang, Yunhong (University of Bath. Department of Architecture and Civil Engineering (UK)) ; Valsami-Jones, Eugenia (University of Birmingham. School of Geography, Earth and Environmental Sciences (UK)) ; Langevin, Dominique (Université Paris Saclay. Laboratoire de Physique des Solides (France)) ; Lynch, Iseult (University of Birmingham. School of Geography, Earth and Environmental Sciences (UK)) ; Mahon, Eugene (University College Dublin. Centre for BioNano Interactions (Ireland)) ; Nelissen, Inge (Flemish Institute for Technological Research. Health Department (Belgium)) ; Piella, Jordi (Institut Català de Nanociència i Nanotecnologia) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Ray, Sikha (Karlsruhe Institute of Technology. Science and Technology of Nanosystems (Germany)) ; Schneider, Reinhard (Karlsruhe Institute of Technology. Laboratory for Electron Microscopy (Germany)) ; Wilkins, Terry (University of Leeds. School of Chemical and Process Engineering (UK)) ; Weiss, Carsten (Karlsruhe Institute of Technology. Institute for Toxicology and Genetics (Germany)) ; Paur, Hanns-Rudolf (Karlsruhe Institute of Technology. Institute for Technical Chemistry (Germany))
A central challenge for the safe design of nanomaterials (NMs) is the inherent variability of NM properties, both as produced and as they interact with and evolve in, their surroundings. This has led to uncertainty in the literature regarding whether the biological and toxicological effects reported for NMs are related to specific NM properties themselves, or rather to the presence of impurities or physical effects such as agglomeration of particles. [...]
2018 - 10.3390/nano8050311
Nanomaterials, Vol. 8, Issue 5 (May 2018) , art. 311  
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4 Nelissen, Inge
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