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9 p, 754.3 KB |
The Role of Arterial Stiffness in the Estimation of Cardiovascular Risk in Liver Transplant Recipients
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Sastre, Lydia (Hospital Clínic i Provincial de Barcelona) ;
García, Raquel (Hospital Clínic i Provincial de Barcelona) ;
Gándara, Julián-Gonzalo (Hospital Clínic i Provincial de Barcelona) ;
Fernandez-Llama, Patricia (Institut d'Investigació Biomèdica Sant Pau) ;
Amor Fernández, Antonio J. (Hospital Clínic i Provincial de Barcelona) ;
Sierra, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Escudé, Laia (Hospital Clínic i Provincial de Barcelona) ;
Ruiz, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Colmenero, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Ortega, Emilio (Hospital Clínic i Provincial de Barcelona) ;
Navasa, Miquel (Hospital Clínic i Provincial de Barcelona) ;
Crespo, Gonzalo (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Long-term cardiovascular (CV) events are a frequent cause of death and disability after liver transplant (LT). Although a more in-depth, risk-adapted control of CV risk factors may result in improved post-LT CV outcomes, an accurate stratification of the CV risk of LT recipients to better implement preventive strategies is lacking. [...]
2021 -  10.1097/TXD.0000000000001272
Transplantation Direct, Vol. 8 Núm. 1 (23 2021) , p. E1272
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2.
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13 p, 276.7 KB |
Eradication of hepatitis C virus and non-liver-related non-acquired immune deficiency syndrome-related events in human immunodeficiency virus/hepatitis C virus coinfection
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Berenguer, Juan (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Rodríguez-Castellano, Elena (Hospital Universitario La Paz (Madrid)) ;
Carrero, Ana (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Von Wichmann, Miguel A. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Montero, Marta (Hospital Universitari i Politècnic La Fe (València)) ;
Galindo, María J. (Hospital Clínico Universitario) ;
Mallolas Masferrer, Josep (Hospital Clínic i Provincial de Barcelona) ;
Crespo Casal, Manuel (Complexo Hospitalario Universitario de Vigo) ;
Téllez, María J. (Hospital Clínico San Carlos (Madrid)) ;
Quereda, Carmen (Hospital Universitario Ramón y Cajal (Madrid)) ;
Sanz, José (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Barros, Carlos (Hospital Universitario de Móstoles (Madrid)) ;
Tural, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santos, Ignacio (Hospital Universitario de la Princesa (Madrid)) ;
Pulido, Federico (Hospital Universitario 12 de Octubre (imas12)) ;
Guardiola Tey, Jose Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Rubio, Rafael (Hospital Universitario 12 de Octubre (imas12)) ;
Ortega, Enrique (Hospital General Universitario) ;
Montes, María L. (Hospital Universitario La Paz (Madrid)) ;
Jusdado, Juan J. (Hospital Universitario Severo Ochoa) ;
Gaspar, Gabriel (Hospital Universitario de Getafe (Madrid)) ;
Esteban, Herminia (Fundación SEIMC-GESIDA) ;
Bellón, José M. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
González-García, Juan (Hospital Universitario La Paz (Madrid)) ;
Universitat Autònoma de Barcelona
We assessed non-liver-related non-acquired immunodeficiency syndrome (AIDS)-related (NLR-NAR) events and mortality in a cohort of human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-coinfected patients treated with interferon (IFN) and ribavirin (RBV), between 2000 and 2008. [...]
2017 - 10.1002/hep.29071
Hepatology, Vol. 66 Núm. 2 (august 2017) , p. 344-356
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3.
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8 p, 1.9 MB |
Obesity and Alzheimer's disease, does the obesity paradox really exist? A magnetic resonance imaging study
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Pegueroles, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez, Amanda (Hospital Clínic i Provincial de Barcelona) ;
Vilaplana, Eduard (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Montal, Victor (Institut d'Investigació Biomèdica Sant Pau) ;
Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ;
Pané, Adriana (Hospital Clínic i Provincial de Barcelona) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Videla Toro, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Casajoana, Anna (Hospital de Barcelona-SCIAS) ;
Clarimón, Jordi (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Ortega, Emilio (Hospital Clínic i Provincial de Barcelona) ;
Vidal, Josep (Hospital Clínic i Provincial de Barcelona) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Mid-life obesity is an established risk factor for Alzheimer's disease (AD) dementia,whereas late-life obesity has been proposed as a protective state. Weight loss, whichpredates cognitive decline, might explain this obesity paradox on AD risk. [...]
2018 - 10.18632/oncotarget.26162
Oncotarget, Vol. 9 Núm. 78 (january 2018) , p. 34691-34698
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4.
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12 p, 1.9 MB |
Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR
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Vigón, Lorena (Instituto de Salud Carlos III) ;
Vázquez-Morón, Sonia (Instituto de Salud Carlos III) ;
Berenguer, Juan (Hospital General Universitario Gregorio Marañón) ;
González-García, Juan (Hospital Universitario La Paz (Madrid)) ;
Jiménez-Sousa, Ma Ángeles (Instituto de Salud Carlos III) ;
Guardiola Tey, Jose Maria (Institut d'Investigació Biomèdia Sant Pau) ;
Crespo Casal, Manuel (Hospital Álvaro Cunqueiro (Vigo)) ;
de los Santos, Ignacio (Hospital Universitario de la Princesa (Madrid)) ;
Von Wichmann, Miguel A. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Carrero, Ana (Hospital General Universitario Gregorio Marañón) ;
Yélamos, María Belén (Universidad Complutense de Madrid) ;
Gómez, Julián (Universidad Complutense de Madrid) ;
Resino, Salvador (Instituto de Salud Carlos III) ;
Martínez, Isidoro (Instituto de Salud Carlos III) ;
Miralles, P. (Hospital General Universitario Gregorio Marañón) ;
López, J.C. (Hospital General Universitario Gregorio Marañón) ;
Parras, F. (Hospital General Universitario Gregorio Marañón) ;
Padilla, B. (Hospital General Universitario Gregorio Marañón) ;
Aldamiz-Echevarría, T. (Hospital General Universitario Gregorio Marañón) ;
Tejerina, F. (Hospital General Universitario Gregorio Marañón) ;
Díez, C. (Hospital General Universitario Gregorio Marañón) ;
Pérez-Latorre, L. (Hospital General Universitario Gregorio Marañón) ;
Fanciulli, C. (Hospital General Universitario Gregorio Marañón) ;
Gutiérrez, I. (Hospital General Universitario Gregorio Marañón) ;
Ramírez, M. (Hospital General Universitario Gregorio Marañón) ;
Carretero, S. (Hospital General Universitario Gregorio Marañón) ;
Bellón, J.M. (Hospital General Universitario Gregorio Marañón) ;
Bermejo, Javier (Hospital General Universitario Gregorio Marañón) ;
Hontañón, V. (Hospital Universitario La Paz (Madrid)) ;
Arribas, Jose (Hospital Universitario La Paz (Madrid)) ;
Montes, M.L. (Hospital Universitario La Paz (Madrid)) ;
Bernardino, I. (Hospital Universitario La Paz (Madrid)) ;
Pascual, J.F. (Hospital Universitario La Paz (Madrid)) ;
Zamora, F. (Hospital Universitario La Paz (Madrid)) ;
Peña, J.M. (Hospital Universitario La Paz (Madrid)) ;
Arnalich, F. (Hospital Universitario La Paz (Madrid)) ;
Díaz, M. (Hospital Universitario La Paz (Madrid)) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Sanz, J. (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Bustinduy, M.J. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Iribarren, J.A. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Rodríguez-Arrondo, F. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Eynde, E.Van den (Hospital Universitari Vall d'Hebron) ;
Pérez, M. (Hospital Universitari Vall d'Hebron) ;
Ribera, E. (Hospital Universitari Vall d'Hebron) ;
Casado, José Luis (Hospital Universitario Ramón y Cajal (Madrid)) ;
Dronda, F. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Moreno, A. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Pérez-Elías, M.J. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Sanfrutos, M.A. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Moreno, S. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Quereda, C. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Arranz, A. (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Casas, E. (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Miguel, J.de (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Schroeder, S. (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Vergas, J. (Hospital Clínico San Carlos (Madrid)) ;
Téllez, M.J. (Hospital Clínico San Carlos (Madrid)) ;
Vinuesa, D. (Hospital Universitario San Cecilio (Granada)) ;
Muñoz, L. (Hospital Universitario San Cecilio (Granada)) ;
Hernández-Quero, J. (Hospital Universitario San Cecilio (Granada)) ;
Ferrer, A. (Hospital Clínico Universitario) ;
Galindo, M.J. (Hospital Clínico Universitario) ;
Ortiz, L. (Hospital General Universitario) ;
Ortega, E. (Hospital General Universitario) ;
Montero, M. (Hospital Universitari La Fe) ;
Blanes, M. (Hospital Universitari La Fe) ;
Cuellar, S. (Hospital Universitari La Fe) ;
Lacruz, J. (Hospital Universitari La Fe) ;
Salavert, M. (Hospital Universitari La Fe) ;
López-Aldeguer, J. (Hospital Universitari La Fe) ;
Pérez, G. (Hospital Universitario de Getafe (Madrid)) ;
Gaspar, G. (Hospital Universitario de Getafe (Madrid)) ;
Yllescas, M. (Fundación SEIMC-GESIDA) ;
Crespo, P. (Fundación SEIMC-GESIDA) ;
Aznar, E. (Fundación SEIMC-GESIDA) ;
Esteban, H. (Fundación SEIMC-GESIDA) ;
Universitat Autònoma de Barcelona
The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who achieved sustained virological response (SVR) with peg-IFNα + ribavirin anti-HCV therapy. [...]
2019 - 10.1038/s41598-019-48592-5
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 12163
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5.
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5 p, 230.8 KB |
Cataract Surgery in Elderly Subjects with Heterozygous Familial Hypercholesterolemia in Prolonged Treatment with Statins
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Marco-Benedí, Victoria (Universidad de Zaragoza. Departamento de Medicina, Psiquiatría y Dermatología) ;
Laclaustra, Martín (Universidad de Zaragoza. Departamento de Medicina, Psiquiatría y Dermatología) ;
Sánchez-Hernández, Rosa M. (Hospital Universitario Insular de Gran Canaria) ;
Ortega, Emilio (Hospital Clínic i Provincial de Barcelona) ;
Pedro-Botet, Juan (Hospital del Mar (Barcelona, Catalunya)) ;
Puzo, Jose (Hospital San Jorge) ;
Civeira, Fernando (Universidad de Zaragoza. Departamento de Medicina, Psiquiatría y Dermatología) ;
Universitat Autònoma de Barcelona
Background: Cataracts are the main cause of blindness and represent one fifth of visual problems worldwide. It is still unknown whether prolonged statin treatment favors the development of cataracts. [...]
2021 - 10.3390/jcm10163494
Journal of clinical medicine, Vol. 10 (august 2021)
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6.
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16 p, 1.0 MB |
Advanced lipoprotein profile disturbances in type 1 diabetes mellitus : A focus on LDL particles
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Amor Fernández, Antonio J. (Hospital Clínic i Provincial de Barcelona) ;
Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ;
Hernández, Marta (Institut d'Investigació Biomédica de Lleida (IRB Lleida)) ;
Giménez, Marga (Hospital Clínic i Provincial de Barcelona) ;
Granado-Casas, Minerva (Institut d'Investigació Biomèdica Sant Pau) ;
Blanco, Jesus (Hospital Clínic i Provincial de Barcelona) ;
Soldevila, Berta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Esmatjes Mompo, Enric (Hospital Clínic i Provincial de Barcelona) ;
Conget, Ignacio (Hospital Clínic i Provincial de Barcelona) ;
Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ortega, Emilio (Hospital Clínic i Provincial de Barcelona) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Lipoprotein disturbances have been associated with increased cardiovascular disease (CVD) risk in type 1 diabetes mellitus (T1DM). We assessed the advanced lipoprotein profile in T1DM individuals, and analysed differences with non-diabetic counterparts. [...]
2020 - 10.1186/s12933-020-01099-0
Cardiovascular diabetology, Vol. 19 Núm. 1 (september 2020) , p. 126
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12 p, 831.3 KB |
Preoperative CA125 Significantly Improves Risk Stratification in High-Grade Endometrial Cancer
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Lombaers, Marike S. (Radboud Institute of Health Sciences (Holanda)) ;
Cornel, Karlijn M. C. (Department of Obstetrics and Gynecology, University of Toronto) ;
Visser, Nicole C. M. (Department of Pathology, Eurofins PAMM (Països Baixos)) ;
Bulten, Johan (Radboud University Medical Center (Holanda)) ;
Küsters-Vandevelde, Heidi V. N. (Department of Pathology, Canisius-Wilhelmina Hospital (Països Baixos)) ;
Amant, Frederic (The Netherlands Cancer Institute (Països Baixos)) ;
Boll, Dorry (Department of Gynecology, Catharina Hospital (Països Baixos)) ;
Bronsert, Peter (University Medical Center) ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Geomini, Peggy M. A. J. (Department of Obstetrics and Gynecology, Maxima Medical Centre (Països Baixos)) ;
Gil-Moreno, Antonio 1965- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
van Hamont, Dennis (Department of Obstetrics and Gynecology, Amphia Hospital (Països Baixos)) ;
Huvila, Jutta (Department of Pathology, University of Turku (Països Baixos)) ;
Krakstad, Camilla (Department of Clinical Science, University of Bergen) ;
Kraayenbrink, Arjan A. (Department of Obstetrics and Gynaecology, Rijnstate Hospital (Països Baixos)) ;
Koskas, Martin (Department of Obstetrics and Gynecology, Bichat-Claude Bernard Hospital (França)) ;
Mancebo, Gemma (Hospital del Mar (Barcelona, Catalunya)) ;
Matías-Guiu, Xavier (Department of Pathology and Molecular Genetics and Research Laboratory, Hospital Universitari Arnau de Vilanova) ;
Ngo, Huy (Department of Obstetrics and Gynecology, Elkerliek Hospital (Països Baixos)) ;
Pijlman, Brenda M. (Department of Obstetrics and Gynecology, Jeroen Bosch Hospital, 5223 GZ 's-Hertogenbosch (Països Baixos)) ;
Vos, Maria Caroline (Department of Obstetrics and Gynecology, Elisabeth-TweeSteden Hospital (Països Baixos)) ;
Weinberger, Vit (Department of Gynecology and Obstetrics, University Hospital Brno, Faculty of Medicine, Masaryk University (República Txeca)) ;
Snijders, Marc P. L. M. (Department of Obstetrics and Gynecology, Canisius-Wilhelmina Hospital (Països Baixos)) ;
van Koeverden, Sebastiaan W. (Department of Radiology and Nuclear Medicine, Radboud University Medical Center (Països Baixos)) ;
Haldorsen, Ingfrid S. (Mohn Medical Imaging and Visualization Centre, Department of Radiology, Haukeland University Hospital, 5021 Bergen, Norway) ;
Reijnen, Casper (Department of Radiation Oncology, Radboud University Medical Center (Països Baixos)) ;
Pijnenborg, Johanna M. A. (Radboud Institute of Health Sciences (Països Baixos)) ;
Universitat Autònoma de Barcelona
Patients with high-grade uterine cancer (UC) have a risk of around 20% of the cancer spreading to the lymph nodes, while this is only around 10% in patients with low-grade uterine cancer. CA125 is a marker that can be detected in blood and is associated with increased tumor spread. [...]
2023 - 10.3390/cancers15092605
Cancers, Vol. 15 (may 2023)
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15 p, 1.9 MB |
In silico Approach for Validating and Unveiling New Applications for Prognostic Biomarkers of Endometrial Cancer
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Coll de la Rubia, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martinez-Garcia, Elena (Luxembourg Institute of Health) ;
Dittmar, Gunnar (Luxembourg Institute of Health) ;
Nazarov, Petr V. (Luxembourg Institute of Health) ;
Bebia, Vicente (Hospital Universitari Vall d'Hebron) ;
Cabrera Díaz, Silvia (Hospital Universitari Vall d'Hebron) ;
Gil-Moreno, Antonio 1965- (Hospital Universitari Vall d'Hebron) ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Endometrial cancer (EC) mortality is directly associated with the presence of poor prognostic factors. Molecular prognostic factors have been identified, but none are used in clinical practice due to lack of validation studies. [...]
2021 - 10.3390/cancers13205052
Cancers, Vol. 13 (october 2021)
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9.
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22 p, 3.0 MB |
Genomic Validation of Endometrial Cancer Patient-Derived Xenograft Models as a Preclinical Tool
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Villafranca-Magdalena, Beatriz (Universitat Autònoma de Barcelona) ;
Masferrer-Ferragutcasas, Carina (Universitat Autònoma de Barcelona) ;
López-Gil, Carlos (Universitat Autònoma de Barcelona) ;
Coll de la Rubia, Eva (Universitat Autònoma de Barcelona) ;
Rebull, Marta (Universitat Autònoma de Barcelona) ;
Parra, Genis (Centre for Genomic Regulation (Barcelona, Catalunya)) ;
García, Ángel (Hospital Universitari Vall d'Hebron) ;
Reques, Armando (Hospital Universitari Vall d'Hebron) ;
Cabrera Díaz, Silvia (Vall d'Hebron Institut d'Oncologia) ;
Colás Ortega, Eva (Universitat Autònoma de Barcelona) ;
Gil-Moreno, Antonio 1965- (Vall d'Hebron Institut d'Oncologia) ;
Moiola, Cristian Pablo (Universitat Autònoma de Barcelona)
Endometrial cancer (EC) is the second most frequent gynecological cancer worldwide. Although improvements in EC classification have enabled an accurate establishment of disease prognosis, women with a high-risk or recurrent EC face a dramatic situation due to limited further treatment options. [...]
2022 - 10.3390/ijms23116266
International journal of molecular sciences, Vol. 23 (june 2022)
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10.
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17 p, 1.5 MB |
Multi-ancestry genome-wide association study of asthma exacerbations
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Herrera-Luis, Esther (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Ortega, Victor E. (División de Medicina Respiratoria. Departamento de Medicina Interna. Mayo Clinic) ;
Ampleford, Elizabeth J. (Department of Internal Medicine. Center for Precision Medicine. Wake Forest School of Medicine) ;
Sio, Yang Yie (Department of Biological Sciences. National University of Singapore) ;
Granell, Raquel (MRC Integrative Epidemiology Unit (IEU). Population Health Sciences. Bristol Medical School. University of Bristol) ;
de Roos, Emmely (Department of Respiratory Medicine. Ghent University Hospital) ;
Terzikhan, Natalie (Department of Respiratory Medicine. Ghent University Hospital) ;
Vergara, Ernesto Elorduy (Institute of Computation Biology. Helmholtz Zentrum München. German Research Center for Environmental Health) ;
Hernandez-Pacheco, Natalia (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Perez-Garcia, Javier (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Martin-Gonzalez, Elena (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Lorenzo-Diaz, Fabian (Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias. Universidad de La Laguna) ;
Hashimoto, Simone (Department of Respiratory Medicine. Amsterdam University Medical Center. University of Amsterdam) ;
Brinkman, Paul (Department of Respiratory Medicine. Amsterdam University Medical Center. University of Amsterdam) ;
Jorgensen, Andrea L. (Department of Health Data Science. Institute of Population Health. University of Liverpool) ;
Yan, Qi (Department of Obstetrics and Gynecology. Columbia University Irving Medical Center) ;
Forno, Erick (Division of Pediatric Pulmonary Medicine. UPMC Children's Hospital of Pittsburgh. University of Pittsburgh) ;
Vijverberg, Susanne J. (Department of Paediatric Respiratory Medicine and Allergy. Emma's Children Hospital. Amsterdam UMC. University of Amsterdam) ;
Lethem, Ryan (MRC Integrative Epidemiology Unit (IEU). Population Health Sciences. Bristol Medical School. University of Bristol) ;
Espuela-Ortiz, Antonio (Universidad de La Laguna. Departamento de Bioquímica, Microbiología, Biología Celular y Genética) ;
Gorenjak, Mario (Center for Human Molecular Genetics and Pharmacogenomics. Faculty of Medicine. University of Maribor) ;
Eng, Celeste (Department of Medicine. University of California San Francisco) ;
González-Pérez, Ruperto (Unidad de Asma Grave. Servicio de Alergología. Hospital Universitario de Canarias.) ;
Hernández-Pérez, José M. (Hospital General de La Palma. Servicio de Neumología) ;
Poza-Guedes, Paloma (Hospital Universitario de Canarias. Unidad de Asma Grave. Servicio de Alergología) ;
Sardón, Olaia (Universidad del País Vasco. Departamento de Pediatría) ;
Corcuera, Paula (Hospital Universitario Donostia. Division of Pediatric Respiratory Medicine) ;
Hawkins, Greg A. (Department of Biochemistry. Wake Forest School of Medicine) ;
Marsico, Annalisa (Computational Health Center. Helmholtz Zentrum München. German Research Center for Environmental Health) ;
Bahmer, Thomas (Airway Research Center North (ARCN). Members of the Germany Center for Lung Research (DZL)) ;
Rabe, Klaus F. (Airway Research Center North (ARCN). Members of the Germany Center for Lung Research (DZL)) ;
Hansen, Gesine (Department of Pediatric Pneumology. Allergology and Neonatology. Hannover Medical School) ;
Kopp, Matthias V. (Department of Paediatric Respiratory Medicine. Inselspital. University Children's Hospital of Bern. University of Bern) ;
Rios, Raimon (Programa de Pós Graduação em Imunologia (PPGIm). Instituto de Ciências da Saúde. Universidade Federal da Bahia (UFBA)) ;
Cruz, Maria Jesús (Hospital Universitari Vall d'Hebron) ;
González-Barcala, Francisco Javier (Complejo Hospitalario Universitario de Santiago de Compostela. Servicio de Neumología) ;
Olaguibel, José María (Complejo Hospitalario de Navarra) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz. Instituto de Investigación Hospital Universitario La Paz. Servicio de Alergología) ;
Canino, Glorisa (Behavioral Sciences Research Institute. University of Puerto Rico) ;
Cloutier, Michelle (Department of Pediatrics. University of Connecticut) ;
Del Pozo, Victoria (Instituto de Investigación Sanitaria Hospital Universitario Fundación Jiménez Díaz. Servicio de Inmunología) ;
Rodriguez-Santana, Jose R. (Centro de Neumología Pediátrica) ;
Korta-Murua, Javier (Universidad del País Vasco. Departamento de Pediatría) ;
Villar, Jesús (Hospital Universitario de Gran Canaria Doctor Negrín. Multidisciplinary Organ Dysfunction Evaluation Research Network. Research Unit) ;
Potočnik, Uros (Laboratory for Biochemistry. Molecular Biology and Genomics. Faculty for Chemistry and Chemical Engineering. University of Maribor) ;
Figueiredo, Camila (Instituto de Ciências da Saúde. Universidade Federal da Bahia) ;
Kabesch, Michael (Department of Paediatric Pneumology and Allergy. University Children's Hospital Regensburg (KUNO)) ;
Mukhopadhyay, Somnath (Population Pharmacogenetics Group. Biomedical Research Institute. Ninewells Hospital and Medical School. University of Dundee) ;
Pirmohamed, Munir (Department of Pharmacology and Therapeutics. Institute of Systems. Molecular and Integrative Biology. University of Liverpool) ;
Hawcutt, Daniel (NIHR Alder Hey Clinical Research Facility. Alder Hey Children's Hospital) ;
Melén, Erik (Sachs' Children's Hospital. South General Hospital) ;
Palmer, Colin (Population Pharmacogenetics Group. Biomedical Research Institute. Ninewells Hospital and Medical School. University of Dundee) ;
Turner, Steve (Child Health. University of Aberdeen) ;
Maitland-van der Zee, Anke H. (Department of Paediatric Respiratory Medicine and Allergy. Emma's Children Hospital. Amsterdam UMC. University of Amsterdam) ;
von Mutius, Erika (Comprehensive Pneumology Center Munich (CPC-M). Member of the German Center for Lung Research) ;
Celedón, Juan C. (Division of Pediatric Pulmonary Medicine. UPMC Children's Hospital of Pittsburgh. University of Pittsburgh) ;
Brusselle, Guy (Department of Respiratory Medicine. Erasmus University Medical Center) ;
Chew, Fook Tim (Department of Biological Sciences. National University of Singapore) ;
Bleecker, Eugene (Division of Genetics. Genomics. and Precision Medicine. Department of Internal Medicine. University of Arizona College of Medicine) ;
Meyers, Deborah (Division of Genetics. Genomics. and Precision Medicine. Department of Internal Medicine. University of Arizona College of Medicine) ;
Burchard, Esteban G. (Department of Bioengineering and Therapeutic Sciences. University of California San Francisco) ;
Pino-Yanes, Maria (Universidad de la Laguna. Instituto de Tecnologías Biomédicas)
Background: Asthma exacerbations are a serious public health concern due to high healthcare resource utilization, work/school productivity loss, impact on quality of life, and risk of mortality. The genetic basis of asthma exacerbations has been studied in several populations, but no prior study has performed a multi-ancestry meta-analysis of genome-wide association studies (meta-GWAS) for this trait. [...]
2022 - 10.1111/pai.13802
Pediatric Allergy and Immunology, Vol. 33 Núm. 6 (june 2022) , p. e13802
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