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7 p, 1.1 MB |
Multidisciplinary management of head and neck cancer : First expert consensus using Delphi methodology from the Spanish Society for Head and Neck Cancer (part 1)
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Maños, Manuel (Hospital Universitari de Bellvitge) ;
Giralt López de Sagredo, Jordi (Hospital Universitari Vall d'Hebron) ;
Rueda Domínguez, Antonio (Hospital Costa del Sol (Marbella)) ;
Cabrera, Joaquín (Hospital Infanta Cristina (Badajoz)) ;
Martínez-Trufero, Javier (Hospital Universitario Miguel Servet (Saragossa)) ;
Marruecos, Jordi (Institut Català d'Oncologia Girona) ;
López Pousa, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Rodrigo, Juan Pablo (Hospital Universitario Central de Asturias) ;
Castelo Fernández, Beatriz (Hospital Universitario La Paz (Madrid)) ;
Martínez-Galán, Joaquina (Hospital Universitario Virgen de las Nieves (Granada)) ;
Arias-De-La-Vega, Fernando Carrillo (Complejo Hospitalario de Navarra) ;
Chaves, Manuel (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Herranz, Jesús (Complejo Hospitalario Universitario de A Coruña) ;
Arrazubi, Virginia (Hospital de Basurto (Bilbao, Biscaia)) ;
Basté, Neus (Hospital Universitari Vall d'Hebron) ;
Castro, Almudena Vizcaya (Hospital Universitario La Paz (Madrid)) ;
Mesía, Ricard (Institut Català d'Oncologia (L'Hospitalet de Llobregat)) ;
Universitat Autònoma de Barcelona
Head and neck cancer is one of the most frequent malignances worldwide. Despite the site-specific multimodality therapy, up to half of the patients will develop recurrence. Treatment selection based on a multidisciplinary tumor board represents the cornerstone of head and neck cancer, as it is essential for achieving the best results, not only in terms of outcome, but also in terms of organ-function preservation and quality of life. [...]
2017 -  10.1016/j.oraloncology.2017.04.004
Oral Oncology, Vol. 70 (july 2017) , p. 58-64
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7 p, 1.5 MB |
A Novel Role for Nanog As An Early Cancer Risk Marker in Patients with Laryngeal Precancerous Lesions
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Rodrigo, Juan P. (Instituto Universitario de Oncología Del Principado de Asturias) ;
Villaronga, M.Ángeles (Instituto Universitario de Oncología Del Principado de Asturias) ;
Menéndez, Sofía T. (Instituto Universitario de Oncología Del Principado de Asturias) ;
Hermida-Prado, Francisco (Instituto Universitario de Oncología Del Principado de Asturias) ;
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Vilaseca, Isabel (Hospital Clínic i Provincial de Barcelona) ;
Allonca, Eva (Instituto Universitario de Oncología Del Principado de Asturias) ;
Pedregal Mallo, Daniel (Instituto Universitario de Oncología Del Principado de Asturias) ;
Astudillo, Aurora (Hospital Universitario Central de Asturias) ;
García-Pedrero, Juana M. (Instituto Universitario de Oncología Del Principado de Asturias) ;
Universitat Autònoma de Barcelona
NANOG is a master regulator of embryonic stem cell pluripotency, found to be frequently aberrantly expressed in a variety of cancers, including laryngeal carcinomas. This study investigates for the first time the role of NANOG expression in early stages of laryngeal tumourigenesis and its potential utility as cancer risk marker. [...]
2017 - 10.1038/s41598-017-11709-9
Scientific reports, Vol. 7 Núm. 1 (january 2017) , p. 11110
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12 p, 813.5 KB |
Carotid blowout syndrome : Modern trends in management
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Suárez, C. (Universidad de Oviedo) ;
Fernández-Alvarez, Verónica (Hospital Universitario de Cabueñes (Gijón)) ;
Hamoir, Marc (St Luc University Hospital) ;
Mendenhall, W.M. (University of Florida) ;
Strojan, Primož (Institute of Oncology of Ljubljana) ;
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Silver, C.E. (University of Arizona) ;
Rodrigo, Juan Pablo (Hospital Universitario Central de Asturias) ;
Rinaldo, Alessandra (University of Udine School of Medicine) ;
Ferlito, Alfio (International Head and Neck Scientific Group) ;
Universitat Autònoma de Barcelona
Carotid blowout syndrome (CBS) refers to rupture of the carotid artery and is an uncommon complication of head and neck cancer that can be rapidly fatal without prompt diagnosis and intervention. CBS develops when a damaged arterial wall cannot sustain its integrity against the patient's blood pressure, mainly in patients who have undergone surgical procedures and radiotherapy due to cancer of the head and neck, or have been reirradiated for a recurrent or second primary tumor in the neck. [...]
2018 - 10.2147/CMAR.S180164
Cancer Management and Research, Vol. 10 (2018) , p. 5617-5628
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19 p, 630.3 KB |
The Selective Role of Open and Endoscopic Approaches for Sinonasal Malignant Tumours
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López, Fernando (Instituto Universitario de Oncología del Principado de Asturias) ;
Shah, Jatin P. (Sechenov University) ;
Beitler, Jonathan J. (Maine General Hospital) ;
Snyderman, Carl H. (University of Pittsburgh School of Medicine) ;
Lund, Valerie (The Royal National Throat Nose and Ear Hospital. UCLH Foundation Trust) ;
Piazza, Cesare (University of Brescia (Itàlia)) ;
Mäkitie, Antti A. (Helsinki University Hospital) ;
Guntinas-Lichius, Orlando (Jena University Hospital (Alemanya)) ;
Rodrigo, Juan P. (Instituto Universitario de Oncología del Principado de Asturias) ;
Kowalski, Luiz P. (University of São Paulo Medical School. Department of Head and Neck Surgery) ;
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Shaha, Ashok (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ;
Homma, Akihiro (Hokkaido University. Graduate School of Medicine) ;
Sanabria, Alvaro (CEXCA Centro de Excelencia en Enfermedades de Cabeza y Cuello) ;
Ferrarotto, Renata (The University of Texas MD Anderson Cancer Center) ;
Lee, Anne W.M. (The University of Hong Kong-Shenzhen Hospital. Clinical Oncology Center) ;
Lee, Victor H.F. (The University of Hong Kong-Shenzhen Hospital. Clinical Oncology Center) ;
Rinaldo, Alessandra (University of Udine School of Medicine) ;
Ferlito, Alfio (International Head and Neck Scientific Group)
Endoscopic endonasal surgery has been demonstrated to be effective in the treatment of selected cases of sinonasal cancers. However, in cases of locally advanced neoplasms, as well as recurrences, the most appropriate approach is still debated. [...]
2022 - 10.1007/s12325-022-02080-x
Advances in Therapy, Vol. 39 Núm. 6 (june 2022) , p. 2379-2397
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13 p, 2.3 MB |
Neutrophil to Lymphocyte Ratio in Oropharyngeal Squamous Cell Carcinoma : A Systematic Review and Meta-Analysis
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Rodrigo, Juan Pablo (Centro de Investigación Biomédica en Red de Cáncer) ;
Sánchez-Canteli, Mario (Universidad de Oviedo) ;
Triantafyllou, Asterios (University of Liverpool) ;
de Bree, Remco (University Medical Center Utrecht) ;
Mäkitie, Antti A. (Helsinki University Hospital) ;
Franchi, Alessandro (University of Pisa) ;
Hellquist, Henrik (University of Algarve) ;
Saba, Nabil F. (Emory University School of Medicine) ;
Stenman, Göran (University of Gothenburg) ;
Takes, Robert P. (Radboud University Medical Center) ;
Valero Mayor, Cristina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Zidar, Nina (Univerza V Ljubljani) ;
Ferlito, Alfio (International Head and Neck Scientific Group (Itàlia)) ;
Universitat Autònoma de Barcelona
Neutrophil-to-lymphocyte ratio (NLR) in peripheral blood samples has been associated with prognosis in several cancers, including head and neck cancer, but in oropharyngeal carcinomas its prognostic value, especially in relation to human papillomavirus (HPV) infection, has been little studied. [...]
2023 - 10.3390/cancers15030802
Cancers, Vol. 15 (january 2023)
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12 p, 1.4 MB |
Prognostic role of intraparotid lymph node metastasis in primary parotid cancer : Systematic review
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Guntinas-Lichius, Orlando (Multidisciplinary Salivary Gland Society) ;
Thielker, Jovanna (Jena University Hospital. Friedrich Schiller University) ;
Robbins, K.Thomas (Southern Illinois University) ;
Olsen, Kerry D. (Mayo Clinic) ;
Shaha, Ashok R. (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ;
Mäkitie, Antti A. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
de Bree, Remco (University Medical Center Utrecht) ;
Vander Poorten, Vincent (University Hospitals Leuven and Department of Oncology. Section Head and Neck Oncology) ;
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Rinaldo, Alessandra (University of Udine School of Medicine) ;
Kowalski, Luiz Paulo (Sao Paulo State University Medical School) ;
Rodrigo, Juan Pablo (Hospital Universitario Central de Asturias. Instituto Universitario de Oncología del Principado de Asturias. Universidad de Oviedo) ;
Hamoir, Marc (St Luc University Hospital and King Albert II Cancer Institute. Brussels. Belgium; Institut de Recherche Expérimentale et Clinique (IREC). Université Catholique de Louvain) ;
Ferlito, Alfio (Coordinator of the International Head and Neck Scientific Group)
Background: The prognostic importance of intraparotid lymph node metastasis (P+) in patients with primary parotid gland carcinoma is unclear. Methods: Nineteen retrospective and noncomparative cohort studies, published between 1992 and 2020, met the inclusion criteria and included 2202 patients for this systematic review. [...]
2021 - 10.1002/hed.26541
Head and Neck, Vol. 43 Núm. 3 (march 2021) , p. 997-1008
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14 p, 2.2 MB |
Current trends and controversies in the management of warthin tumor of the parotid gland
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Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Hernandez-Prera, Juan C. (Department of Pathology. Moffitt Cancer Center) ;
Silver, Carl E. (Department of Surgery. University of Arizona College of Medicine) ;
Casasayas, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Simo, Ricard S. (Department of Otorhinolaryngology Head and Neck Surgery. Guy's and St Thomas' Hospital NHS Foundation Trust) ;
Vander Poorten, Vincent (Department of Oncology. Section Head and Neck Oncology. KU Leuven) ;
Guntinas-Lichius, Orlando (Facial Nerve Center. Jena University Hospital) ;
Bradley, Patrick (Nottingham University Hospitals NHS Trust (Regne Unit)) ;
Tong-Ng, Wai (Department of Clinical Oncology. LKS Faculty of Medicine. The University of Hong Kong) ;
Rodrigo, Juan Pablo (Instituto de Investigación Sanitaria del Principado de Asturias (ISPA). Instituto Universitario de Oncología del Principado de Asturias (IUOPA). University of Oviedo CIBERONC-ISCIII) ;
Mäkitie, Antti A (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Rinaldo, Alessandra (University of Udine School of Medicine) ;
Kowalski, Luiz Paulo (Head and Neck Surgery and Otorhinolaryngology Department. A.C. Camargo Cancer Center) ;
Sanabria, Alvaro (Department of Surgery. School of Medicine. Universidad de Antioquia. IPS Universitaria-Hospital Universitario San Vicente Fundación) ;
de Bree, Remco (University Medical Center Utrecht) ;
Takes, Robert P. (Radboud University Medical Center) ;
López, Fernando (Instituto de Investigación Sanitaria del Principado de Asturias (ISPA). Instituto Universitario de Oncología del Principado de Asturias (IUOPA). University of Oviedo CIBERONC-ISCIII) ;
Olsen, Kerry D. (Department of Otorhinolaryngology. Mayo Clinic) ;
Shaha, Ashok R. (Head and Neck Service. Memorial Sloan-Kettering Cancer Center) ;
Ferlito, Alfio (Coordinator of the International Head and Neck Scientific Group) ;
Universitat Autònoma de Barcelona
Purpose: To review the current options in the management of Warthin tumors (WTs) and to propose a working management protocol. Methods: A systematic literature search was conducted using PubMed and ScienceDirect database. [...]
2021 - 10.3390/diagnostics11081467
Diagnostics, Vol. 11 Núm. 8 (august 2021) , p. 1467
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20 p, 4.5 MB |
TSPAN1 : a Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance
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Garcia Mayea, Yoelsis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mir Pérez, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Carballo, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Castellvi, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Temprana-Salvador, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lorente, Juan (Hospital Universitari Vall d'Hebron) ;
Benavente, Sergi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Pedrero, Juana María (Centro de Investigación Biomédica en Red de Cáncer) ;
Allonca, Eva (Centro de Investigación Biomédica en Red de Cáncer) ;
Rodrigo, Juan Pablo (Centro de Investigación Biomédica en Red de Cáncer) ;
LLeonart, Matilde E. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Sensitization of resistant cells and cancer stem cells (CSCs) represents a major challenge in cancer therapy. A proteomic study revealed tetraspanin-1 (TSPAN1) as a protein involved in acquisition of cisplatin (CDDP) resistance (Data are available via ProteomeXchange with identifier PXD020159). [...]
2020 - 10.3390/cancers12113269
Cancers, Vol. 12 Núm. 11 (2020) , p. 3269
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8 p, 252.0 KB |
Is There A Role for Limited Parotid Resections for Primary Malignant Parotid Tumors?
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Quer, Miquel (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Olsen, Kerry D. (Mayo Clinic. Department of Otorhinolaryngology) ;
Silver, Carl E. (University of Arizona College of Medicine. Department of Surgery) ;
Hamoir, Marc (St Luc University Hospital and King Albert II Cancer Institute. Department of Head and Neck Surgery) ;
Mäkitie, Antti A. (University of Helsinki. Faculty of Medicine) ;
Rodrigo, Juan Pablo (Hospital Universitario Central de Asturias) ;
Vander Poorten, Vincent (University Hospitals Leuven (Bèlgica)) ;
Takes, Robert P. (Radboud University Medical Center) ;
Hellquist, Henrik (University of Algarve. Department of Biomedical Sciences and Medicine) ;
García Lorenzo, Jacinto (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Guntinas-Lichius, Orlando (Jena University Hospital (Alemanya)) ;
de Bree, Remco (University Medical Center Utrecht) ;
Suárez, Carlos (Instituto de Investigación Sanitaria del Principado de Asturias) ;
Kowalski, Luiz P. (Centro de Tratamento e Pesquisa Hospital do Cancer A.C. Camargo) ;
Vartanian, José G. (Hospital do Cancer A.C. Camargo) ;
Sanabria, Alvaro (Universidad de Antioquia. Department of Surgery) ;
Shaha, Ashok R. (Memorial Sloan Kettering Cancer Center) ;
Zbären, Peter (Universitätsspital Bern. Department of Otorhinolaryngology-Head and Neck Surgery) ;
Rinaldo, Alessandra (University of Udine. School of Medicine) ;
Ferlito, Alfio (International Head and Neck Scientific Group)
Background: Lateral or total parotidectomy are the standard surgical treatmentsfor malignant parotid tumors. However, some authors have proposed a more limited procedure. (2) Methods: We performed a review of the literature on this topic. [...]
2020 - 10.3390/surgeries1010002
Surgeries, Vol. 1 Núm. 1 (2020) , p. 2
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14 p, 2.3 MB |
Distinctive Expression and Amplification of Genes at 11q13 in Relation to HPV Status with Impact on Survival in Head and Neck Cancer Patients
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Hermida-Prado, Francisco (Centro de Investigación Biomédica en Red de Cáncer) ;
Menéndez, Sofía T. (Centro de Investigación Biomédica en Red de Cáncer) ;
Albornoz-Afanasiev, Pablo (Hospital Universitario Central de Asturias) ;
Granda-Diaz, Rocío (Centro de Investigación Biomédica en Red de Cáncer) ;
Álvarez-Teijeiro, Saúl (Centro de Investigación Biomédica en Red de Cáncer) ;
Villaronga, M. Ángeles (Centro de Investigación Biomédica en Red de Cáncer) ;
Allonca, Eva (Centro de Investigación Biomédica en Red de Cáncer) ;
Alonso-Durán, Laura (Hospital Universitario Central de Asturias) ;
León i Vintró, Xavier (Institut d'Investigació Biomèdica Sant Pau) ;
Alemany, Laia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Mena, Marisa (Institut Català d'Oncologia) ;
del-Rio-Ibisate, Nagore (Centro de Investigación Biomédica en Red de Cáncer) ;
Astudillo, Aurora (Hospital Universitario Central de Asturias) ;
Rodríguez, René (Centro de Investigación Biomédica en Red de Cáncer) ;
Rodrigo, Juan Pablo (Centro de Investigación Biomédica en Red de Cáncer) ;
García-Pedrero, Juana María (Centro de Investigación Biomédica en Red de Cáncer) ;
Universitat Autònoma de Barcelona
Clear differences have been established between head and neck squamous cell carcinomas (HNSCC) depending on human papillomavirus (HPV) infection status. This study specifically investigated the status of the CTTN, CCND1 and ANO1 genes mapping at the 11q13 amplicon in relation to the HPV status in HNSCC patients. [...]
2018 - 10.3390/jcm7120501
Journal of clinical medicine, Vol. 7 (december 2018)
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