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Depósito Digital de Documentos de la UAB Encontrados 2 registros  La búsqueda tardó 0.01 segundos. 
1.
12 p, 1.7 MB Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma : the oncogenic role of the ligands / Almazán-Moga, Anna (Hospital Universitari Vall d'Hebron) ; Zarzosa, Patricia (Hospital Universitari Vall d'Hebron) ; Molist, C. (Hospital Universitari Vall d'Hebron) ; Velasco, Pablo (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Pyczek, J. (Institute of Human Genetics, University of Goettingen) ; Simon-Keller, K. (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Giralt, Irina (Hospital Universitari Vall d'Hebron) ; Vidal, I (Hospital Universitari Vall d'Hebron) ; Navarro, N. (Hospital Universitari Vall d'Hebron) ; Segura, M. F. (Hospital Universitari Vall d'Hebron) ; Soriano, Aroa (Hospital Universitari Vall d'Hebron) ; Navarro, Susanna (Universitat de València. Departament de Patologia) ; Tirado, O. M. (Institut d'Investigació Biomèdica de Bellvitge) ; Ferreres Piñas, Joan Carles (Hospital Universitari Vall d'Hebron) ; Santamaria, A. (Hospital Universitari Vall d'Hebron) ; Rota, R. (Ospedale Pediatrico Bambino Gesù, IRCCS) ; Hahn, H. (Institute of Human Genetics, University of Goettingen) ; Sánchez de Toledo, J.. (Hospital Universitari Vall d'Hebron) ; Roma, Josep (Hospital Universitari Vall d'Hebron) ; Gallego, Soledad (Hospital Universitari Vall d'Hebron)
Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children. The Hedgehog (HH) pathway is known to develop an oncogenic role in RMS. However, the molecular mechanism that drives activation of the pathway in RMS is not well understood. [...]
2017 - 10.1038/bjc.2017.305
British Journal of Cancer, Vol. 117 (09 2017) , p. 1314-1325  
Registro completo - Creative Commons
2.
12 p, 5.0 MB Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient / Saxena, Abhishek (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Stevens, Jo (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Cetin, Hakan (John Radcliffe Hospital (Oxford, Regne Unit)) ; Koneczny, Inga (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Webster, Richard (John Radcliffe Hospital (Oxford, Regne Unit)) ; Lazaridis, Konstantinos (Hellenic Pasteur Institute) ; Tzartos, Socrates (Hellenic Pasteur Institute) ; Vrolix, Kathleen (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Nogales, Gisela (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Machiels, Barbie (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Molenaar, Peter C. (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Damoiseaux, Jan (Central Diagnostic Laboratory, Maastricht University Medical Center) ; De Baets, Marc H. (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Simon-Keller, Katja (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Marx, Alexander (Institute of Pathology, University Medical Centre Mannheim, University of Heidelberg) ; Vincent, Angela (John Radcliffe Hospital (Oxford, Regne Unit)) ; Losen, Mario (Maastricht University. Department of Psychiatry and Neuropsychology) ; Martinez-Martinez, Pilar (Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University) ; Universitat Autònoma de Barcelona
We report here the sequence and functional characterization of a recombinantly expressed.
autoantibody (mAb 131) previously isolated from a myasthenia gravis patient by immortalization of thymic B cells using Epstein-Barr virus and TLR9 activation. The antibody is characterized by a high degree of somatic mutations as well as a 6 amino acid insertion within the VHCDR2. [...]
2017 - 10.1038/s41598-017-14350-8
Scientific reports, Vol. 7 (october 2017) , p. 1-12  
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1 Simon-Keller, K.
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