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15 p, 2.1 MB |
AAV-mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice
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Roig-Soriano, Joan (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Griñán-Ferré, Christian (Universitat de Barcelona. Institut de Neurociències) ;
Espinosa-Parrilla, J. F. (Universitat Autònoma de Barcelona) ;
Abraham, Carmela R (Boston University School of Medicine) ;
Bosch i Merino, Assumpció (Instituto de Salud Carlos III) ;
Pallàs, Mercè (Universitat de Barcelona. Institut de Neurociències) ;
Chillón Rodríguez, Miguel (Institució Catalana de Recerca i Estudis Avançats)
Senescence represents a stage in life associated with elevated incidence of morbidity and increased risk of mortality due to the accumulation of molecular alterations and tissue dysfunction, promoting a decrease in the organism's protective systems. [...]
2022 -  10.1111/acel.13581
Aging Cell, Vol. 21 (march 2022)
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14 p, 2.0 MB |
Safety and Efficacy of Devices Delivering Inhaled Antibiotics among Adults with Non-Cystic Fibrosis Bronchiectasis : A Systematic Review and a Network Meta-Analysis
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Tejada, Sofia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramírez-Estrada, Sergio (Clínica Corachán. Intensive Care Department) ;
Forero, Carlos G. (Universitat Internacional de Catalunya) ;
Gallego, Miguel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Soriano, Joan B.. (Universidad Autónoma de Madrid) ;
Cardinal-Fernández, Pablo A. (HM Group (Madrid)) ;
Ehrmann, Stephan (Université de Tours. Centre d'étude des Pathologies Respiratoires) ;
Rello, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca)
It remains unknown whether the type of aerosol generating device is affecting efficacy and safety among non-cystic fibrosis bronchiectasis (NCFB) adults. The proposal of this network meta-analysis (NMA) is to evaluate effectiveness and safety of inhaled antibiotics administered via dry powder inhaler (DPI) and via nebulizers (SVN) among adult patients with NCFB. [...]
2022 - 10.3390/antibiotics11020275
Antibiotics, Vol. 11 Núm. 2 (february 2022)
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13.
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15 p, 1.6 MB |
Distribution and Outcomes of a Phenotype-Based Approach to Guide COPD Management : Results from the CHAIN Cohort
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Cosio, Borja G.. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Soriano, Joan B.. (Instituto de Investigación Hospital Universitario de la Princesa) ;
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Calle Rubio, Myriam (Hospital Clínico San Carlos (Madrid)) ;
Soler, Juan José (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
De Torres, Juan Pablo (Clínica Universidad de Navarra) ;
Marín, Jose Maria (Hospital Universitario Miguel Servet (Saragossa)) ;
Martínez González, Cristina (Hospital Universitario Central de Asturias) ;
de Lucas, Pilar (Hospital General Universitario Gregorio Marañón) ;
Mir, Isabel (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Peces-Barba, Germán (Hospital Universitario Fundación Jiménez Díaz) ;
Feu-Collado, Nuria (Instituto Maimónides de Investigación Biomédica de Córdoba) ;
Solanes García, Ingrid (Institut d'Investigació Biomèdica Sant Pau) ;
Alfageme, Inmaculada (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Universitat Autònoma de Barcelona
The Spanish guideline for COPD (GesEPOC) recommends COPD treatment according to four clinical phenotypes: non-exacerbator phenotype with either chronic bronchitis or emphysema (NE), asthma-COPD overlap syndrome (ACOS), frequent exacerbator phenotype with emphysema (FEE) or frequent exacerbator phenotype with chronic bronchitis (FECB). [...]
2016 - 10.1371/journal.pone.0160770
PloS one, Vol. 11 (september 2016)
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14.
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10 p, 652.2 KB |
Altitude and COPD prevalence : analysis of the PREPOCOL-PLATINO-BOLD-EPI-SCAN study
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Horner, Andreas (Paracelsus Medical University) ;
Soriano, Joan B.. (Instituto de Investigación Hospital Universitario de la Princesa) ;
Puhan, Milo A. (University of Zurich Epidemiology, Biostatistics and Prevention Institute) ;
Studnicka, Michael (Paracelsus Medical University) ;
Kaiser, Bernhard (Johannes-Kepler-University) ;
Vanfleteren, Lowie E. G. W. (Program Development Centre) ;
Gnatiuc, Louisa (Imperial College) ;
Burney, Peter (Imperial College) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Rio, Francisco (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Ancochea, Julio (Universidad Autónoma de Madrid) ;
Menezes, Ana M. (Universidade Federal de Pelotas) ;
Perez-Padilla, Rogelio (Instituto Nacional de Enfermedades Respiratorias) ;
Montes de Oca, Maria (Universidad Central de Venezuela) ;
Torres-Duque, Carlos A. (Asociación Colombiana de Neumología y Cirugía de Tórax) ;
Caballero, Andres (Clínica Reina Sofía, Bogotá, Colombia) ;
González-García, Mauricio (Fundación Neumológica Colombiana) ;
Buist, Sonia (Oregon Health and Science University) ;
Flamm, Maria (Institute of General Practice) ;
Lamprecht, Bernd (Johannes-Kepler-University) ;
Universitat Autònoma de Barcelona
COPD prevalence is highly variable and geographical altitude has been linked to it, yet with conflicting results. We aimed to investigate this association, considering well known risk factors. A pooled analysis of individual data from the PREPOCOL-PLATINO-BOLD-EPI-SCAN studies was used to disentangle the population effect of geographical altitude on COPD prevalence. [...]
2017 - 10.1186/s12931-017-0643-5
Respiratory Research, Vol. 18 (august 2017)
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15.
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14 p, 1.3 MB |
Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain : A multilevel, cross-sectional analysis of the EPOCONSUL study
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Calle Rubio, Myriam (Universidad Complutense de Madrid) ;
Soriano, Joan B.. (Instituto de Investigación Hospital Universitario de la Princesa) ;
López-Campos, José Luis (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Soler-Cataluña, Juan J. (Pulmonary Department, H. de Arnau de Vilanova, Valencia) ;
Alcázar-Navarrete, Bernardino (Pulmonary Department, Hospital de Alta Resolución de Loja) ;
Rodríguez González-Moro, José Miguel (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Miravitlles, Marc (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Barrecheguren, Miriam (Hospital Universitari Vall d'Hebron) ;
Fuentes Ferrer, Manuel Enrique (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Rodriguez Hermosa, Juan Luis (Universidad Complutense de Madrid) ;
Universitat Autònoma de Barcelona
Alpha-1 antitrypsin deficiency (AATD) is the most common hereditary disorder in adults, but is under-recognized. In Spain, the number of patients diagnosed with AATD is much lower than expected according to epidemiologic studies. [...]
2018 - 10.1371/journal.pone.0198777
PloS one, Vol. 13 (june 2018)
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16.
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10 p, 1.2 MB |
Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging : a pooled analysis of individual patient data
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García Castillo, Elena (Hospital Universitario de la Princesa (Madrid)) ;
Alonso Pérez, Tamara (Hospital Universitario de la Princesa (Madrid)) ;
Ancochea, Julio (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Pastor Sanz, Maria Teresa (Instituto de Investigación Hospital Universitario de la Princesa) ;
Almagro, Pere (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Martínez-Camblor, Pablo (Geisel School of Medicine at Dartmouth) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rodríguez-Carballeira, Mónica (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Navarro, Annie (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Lamprecht, Bernd (Kepler-University-Hospital) ;
Ramírez-García Luna, Ana S. (Universidad Autónoma de San Luis Potosí (Mèxic)) ;
Kaiser, Bernhard (Paracelsus Medical University Hospital) ;
Alfageme, Inmaculada (Universidad de Sevilla) ;
Casanova, Ciro (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Esteban, Cristóbal (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Soler-Cataluña, Juan J. (Hospital Arnau de Vilanova (València)) ;
De Torres, Juan Pablo (Queen's University) ;
Celli, Bartolomé R. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Marín, Jose M. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
ter Riet, Gerben (Amsterdam UMC) ;
Sobradillo, Patricia (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Lange, Peter (Copenhagen University) ;
Garcia-Aymerich, Judith (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Antó i Boqué, Josep Maria (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Turner, Alice M. (University of Birmingham) ;
Han, MeiLan K. (University of Michigan) ;
Langhammer, Arnulf (Nord-Trøndelag Hospital Trust) ;
Vikjord, Sigrid Anna Aalberg (Norwegian University of Science and Technology) ;
Sternberg, Alice (Johns Hopkins Bloomberg School of Public Health) ;
Leivseth, Linda (Northern Norway Regional Health Authority) ;
Bakke, Per (University of Bergen) ;
Johannessen, Ane (University of Bergen) ;
Oga, Toru (Kyoto University, Kyoto) ;
Cosio, Borja G.. (Institut d’Investigació Sanitària Illes Balears) ;
Echazarreta, Andrés L. (Servicio de Neumonología, Hospital San Juan de Dios de La Plata) ;
Roche, Nicolás (APHP Centre-University of Paris) ;
Burgel, Pierre-Regis (APHP Centre-University of Paris) ;
Sin, Don D. (University of British Columbia) ;
Puhan, Milo A. (University of Zurich) ;
López-Campos, José Luis (Instituto de Biomedicina de Sevilla) ;
Carrasco, Laura (Instituto de Biomedicina de Sevilla) ;
Soriano, Joan B.. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Universitat Autònoma de Barcelona
In 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A-4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems. [...]
2020 - 10.1183/23120541.00253-2020
ERJ Open Research, Vol. 6 (november 2020)
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17.
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9 p, 627.6 KB |
Secondhand smoke exposure assessment in outdoor hospitality venues across 11 European countries
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Henderson, Elisabet (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Continente, Xavier (Institut d'Investigació Biomèdica Sant Pau) ;
Fernández, Esteve (Consortium for Biomedical Research in Respiratory Diseases (CIBERES)) ;
Tigova, Olena (Consortium for Biomedical Research in Respiratory Diseases (CIBERES)) ;
Cortés-Francisco, Nuria (Institut d'Investigació Biomèdica Sant Pau) ;
Gallus, Silvano (Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Department of Environmental Health Sciences) ;
Lugo, Alessandra (Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Department of Environmental Health Sciences) ;
Semple, Sean (Institute for Social Marketing and Health, University of Stirling) ;
Dobson, Ruaraidh (Institute for Social Marketing and Health, University of Stirling) ;
Clancy, Luke (TobaccoFree Research Institute Ireland) ;
Keogan, Sheila (TobaccoFree Research Institute Ireland) ;
Ruprecht, Ario (Fondazione IRCCS Istituto Nazionale Dei Tumori) ;
Borgini, Alessandro (Fondazione IRCCS Istituto Nazionale Dei Tumori) ;
Tzortzi, Anna (George D. Behrakis Research Lab, Hellenic Cancer Society) ;
Vyzikidou, Vergina K. (George D. Behrakis Research Lab, Hellenic Cancer Society) ;
Gorini, Giuseppe (Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO)) ;
López-Nicolás, Angel (Universidad Politécnica de Cartagena) ;
Soriano, Joan B.. (Hospital Universitario de la Princesa (Madrid)) ;
Geshanova, Gergana (Smoke-free Life Coalition) ;
Osman, Joseph (OFT Conseil, Office Français de Santé et Bien-être Au Travail) ;
Mons, Ute (University Hospital Cologne) ;
Przewozniak, Krzysztof (Collegium Civitas) ;
Precioso, José (Instituto de Educação, Universidade do Minho) ;
Brad, Ramona (Healthy Romania Generation 2035 Association) ;
López, Maria J. (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Due to partial or poorly enforced restrictions secondhand tobacco smoke (SHS) is still present in outdoor hospitality venues in many European countries. This study aimed to assess SHS concentrations in outdoor hospitality venues across Europe and identify contextual exposure determinants. [...]
2021 - 10.1016/j.envres.2021.111355
Environmental Research, Vol. 200 (september 2021)
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18.
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14 p, 481.8 KB |
Nefer, Sinuhe and clinical research assessing post-COVID-19 syndrome
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Soriano, Joan B.. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Waterer, Grant (School of Medicine, University of Western Australia, Perth, Australia) ;
Peñalvo, Jose Luis (Instituto de Investigación Hospital Universitario de la Princesa) ;
Rello, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
In the immortal classical novel by Finnish writer Mika Waltari (1908-1979) (fig. 1), Nefer, a beautiful and cunning Egyptian courtesan, seduces and befools Sinuhe, the pharaoh's physician. Sinuhe is bewitched by her charms and sacrifices everything for her - even his parents' house and grave - only to be cruelly rejected when Nefer tires of playing with him. [...]
2020 - 10.1183/13993003.04423-2020
European respiratory journal, december 2020
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