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12 p, 617.6 KB |
Diabetes Does Not Increase the Risk of Hospitalization Due to COVID-19 in Patients Aged 50 Years or Older in Primary Care-APHOSDIAB-COVID-19 Multicenter Study
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Orozco-Beltrán, Domingo (Universidad Miguel Hernández. Departamento de Medicina Clínica) ;
Merino-Torres, Juan Francisco (Universidad de Valencia. Hospital Universitari i Politècnic La Fe. Servicio de Endocrinología y Nutrición) ;
Pérez Pérez, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Cebrián-Cuenca, Ana M (Primary Care Research Group. Biomedical Research Institute of Murcia) ;
Párraga-Martínez, Ignacio (Health Center Zone VIII. Servicio de Salud Castilla la Mancha) ;
Ávila Lachica, Luis (Consultorio de Almáchar. UGC Vélez Norte) ;
Rojo-Martínez, G (Instituto de Investigación Biomédica de Málaga) ;
Pomares-Gómez, Francisco J. (Plan de Diabetes Mellitus de la Comunidad Valenciana. Hospital Universitario San Juan de Alicante) ;
Álvarez-Guisasola, Fernando (Centro de Salud Ribera de Órbigo. Consejería de Salud Castilla León) ;
Sánchez-Molla, Manuel (Médico de Familia. Hospital General Universitario de Elche) ;
Gutiérrez, Felix (Centro de Investigación Biomédica en Red Enfermedades Infecciosas) ;
Ortega, Francisco J. (Centro Salud Campos Lampreana. Consejería de Salud Castilla y León) ;
Mata-Cases, Manel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol. Grup DAP-Cat. Unitat de Suport a la Recerca) ;
Carretero Anibarro, Enrique (Centro de Salud José Gallego Arroba. Servicio Andauz de Salud) ;
Vilaseca, Josep Maria (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ;
Quesada, Jose A. (Universidad Miguel Hernández. Departamento de Medicina Clínica) ;
Universitat Autònoma de Barcelona
The purpose of this study was to identify clinical, analytical, and sociodemographic variables associated with the need for hospital admission in people over 50 years infected with SARS-CoV-2 and to assess whether diabetes mellitus conditions the risk of hospitalization. [...]
2022 -  10.3390/jcm11082092
Journal of clinical medicine, Vol. 11 Núm. 8 (april 2022) , p. 2092
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22 p, 623.3 KB |
Polymorphism AGT2 (rs4762) is involved in the development of dermatologic events : Proof-of-concept in hepatocellular carcinoma patients treated with sorafenib
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Sapena, Victor (Hospital Clínic i Provincial de Barcelona) ;
Iavarone, Massimo ;
Boix, Loreto (Hospital Clínic i Provincial de Barcelona) ;
Facchetti, Floriana ;
Guarino, Maria ;
Sanduzzi Zamparelli, Marco (Hospital Clínic i Provincial de Barcelona) ;
Granito, Alessandro ;
Samper, Esther (Hospital Clínic i Provincial de Barcelona) ;
Scartozzi, Mario ;
Corominas, Josep (Hospital Clínic i Provincial de Barcelona) ;
Marisi, Giorgia ;
Díaz, Alba (Hospital Clínic i Provincial de Barcelona) ;
Casadei-Gardini, Andrea ;
Gramantieri, Laura ;
Lampertico, Pietro ;
Morisco, Filomena ;
Torres, Ferran (Hospital Clínic i Provincial de Barcelona) ;
Bruix, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Reig, María (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Dermatologic adverse events (DAEs) are associated with a better outcome in patients with hepatocellular carcinoma (HCC) irrespective of the therapeutic agent received. The exact mechanisms associated with the development of DAEs are unknown although several studies point to direct toxicity of tyrosine kinase inhibitors (TKIs) to the skin or an immune-mediated reaction triggered by the oncologic treatment. [...]
2022 - 10.4254/wjh.v14.i7.1438
World Journal of Hepatology, Vol. 14 (july 2022) , p. 1438-1458
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10 p, 474.6 KB |
Evolving Concepts on Inflammatory Biomarkers and Malnutrition in Chronic Kidney Disease
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Graterol Torres, Fredzzia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Molina, María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Soler-Majoral, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Romero-González, Gregorio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodríguez Chitiva, Néstor (Institut Germans Trias i Pujol) ;
Troya-Saborido, Maribel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Socias Rullan, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Burgos, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Paúl Martínez, Javier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Urrutia Jou, Marina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cañameras, Carles (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Riera Sadurní, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vila, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bover, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
While patient care, kidney replacement therapy, and transplantation techniques for chronic kidney disease (CKD) have continued to progress, the incidence of malnutrition disorders in CKD appears to have remained unchanged over time. [...]
2022 - 10.3390/nu14204297
Nutrients, Vol. 14 (october 2022)
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7 p, 824.9 KB |
Utilisation of drugs for the treatment of psychiatric diseases in the pediatric population : focus on off-label use
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Pesiou, Stella (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Barcelo, Rafel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Fradera, Marc (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Torres, Ferran (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Pontes García, Caridad (Institut d'Investigació Biomèdica de Bellvitge)
Psychotropics are increasingly used in pediatrics, often as off-label medicines. The guarantees of safety and efficacy are not always granted in clinical practice compared to adult authorised indications. [...]
2023 - 10.3389/fphar.2023.1157135
Frontiers in Pharmacology, Vol. 14 (june 2023)
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16 p, 2.0 MB |
Vitamin D Supplementation and Its Impact on Mortality and Cardiovascular Outcomes : Systematic Review and Meta-Analysis of 80 Randomized Clinical Trials
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Ruiz-García, Antonio (Centro de Salud Universitario Pinto) ;
Pallares-Carratala, Vicente (Universitat Jaume I) ;
Turégano-Yedro, Miguel (Centro de Salud Aldea Moret) ;
Torres, Ferran (Universitat Autònoma de Barcelona) ;
Sapena, Victor (Universitat Autònoma de Barcelona) ;
Martin-Gorgojo, Alejandro (Ayuntamiento de Madrid) ;
Martin-Moreno, Jose M. (Hospital Clínic Universitàri de València)
The impact of vitamin D supplementation on cardiovascular outcomes and mortality risk reduction remains unclear due to conflicting study findings. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs), published between 1983 and 2022, that reported the effect of vitamin D supplementation in adults versus placebo or no treatment on all-cause mortality (ACM), cardiovascular mortality (CVM), non-cardiovascular mortality (non-CVM), and cardiovascular morbidities. [...]
2023 - 10.3390/nu15081810
Nutrients, Vol. 15 (april 2023)
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14 p, 3.3 MB |
A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study
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Español-Rego, Marta (Hospital Clínic i Provincial de Barcelona) ;
Fernández-Martos, Carlos (Instituto Valenciano de Oncología. Medical Oncology Department) ;
Elez, Elena (Vall d'Hebron Institut d'Oncologia) ;
Foguet, Carles (Universitat de Barcelona. Department of Biochemistry and Molecular Medicine) ;
Pedrosa, Leire (Hospital Clínic i Provincial de Barcelona) ;
Rodríguez, Nuria (Centro de Investigación Biomédica en Red de Cáncer) ;
Ruiz-Casado, Ana (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Pineda, Estela (Hospital Clínic i Provincial de Barcelona) ;
Cid, Joan (Hospital Clínic i Provincial de Barcelona) ;
Cabezón, Raquel (Hospital Clínic i Provincial de Barcelona) ;
Oliveres, Helena (Hospital Clínic i Provincial de Barcelona) ;
Lozano, Miquel (Hospital Clínic i Provincial de Barcelona) ;
Ginés, Angels (Instituto Nacional de La Salud Carlos III. Networked Center for Hepatic and Digestive Diseases) ;
García-Criado, Angeles (Hospital Clínic i Provincial de Barcelona) ;
Ayuso, Juan Ramon (Hospital Clínic i Provincial de Barcelona) ;
Pagés, Mario (Hospital Clínic i Provincial de Barcelona) ;
Cuatrecasas, Miriam (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Torres Benítez, Ferran (Universitat Autònoma de Barcelona. Unitat de Bioestadística) ;
Thomson, Timothy (Universidad Peruana Cayetano Heredia) ;
Cascante, Marta (Instituto Nacional de La Salud Carlos III) ;
Benítez Ribas, Daniel (Hospital Clínic i Provincial de Barcelona) ;
Torres Benítez, Ferran (Instituto Nacional de La Salud Carlos III)
Immune check-point blockade (ICB) has shown clinical benefit in mismatch repair-deficient/microsatellite instability high metastatic colorectal cancer (mCRC) but not in mismatch repair-proficient/microsatellite stable patients. [...]
2022 - 10.1007/s00262-022-03283-5
Cancer Immunology, Immunotherapy, Vol. 72 (september 2022) , p. 827-840
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16 p, 1.7 MB |
Excess hospitalizations and mortality associated with seasonal influenza in Spain, 2008-2018
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Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Díez-Domingo, J. (Universitat de València) ;
Martinón-Torres, F. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Redondo Margüello, E. (International Health Center Madrid Health) ;
de Lejarazu Leonardo, R. Ortiz (Hospital Clínico Universitario de Valladolid) ;
Carmo, M. (IQVIA) ;
Bizouard, G. (IQVIA) ;
Drago, G. (Sanofi) ;
López-Belmonte, J. L. (Sanofi) ;
Bricout, H. (Sanofi) ;
de Courville, C. (Sanofi) ;
Gil-de-Miguel, A. (Universidad Rey Juan Carlos) ;
Universitat Autònoma de Barcelona
Influenza may trigger complications, particularly in at-risk groups, potentially leading to hospitalization or death. However, due to lack of routine testing, influenza cases are infrequently coded with influenza-specific diagnosis. [...]
2023 - 10.1186/s12879-023-08015-3
BMC Infectious diseases, Vol. 23 (february 2023)
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