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Pan-cancer proteogenomics connects oncogenic drivers to functional states
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Li, Yize (Washington University in St. Louis) ;
Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Tokheim, Collin (Harvard T.H. Chan School of Public Health) ;
Bailey, Matthew H. (Brigham Young University) ;
Yaron, Tomer (Weill Cornell Medicine) ;
Stathias, Vasileios (University of Miami Miller School of Medicine) ;
Geffen, Yifat (Massachusetts General Hospital) ;
Imbach, Kathleen (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Cao, Song (McDonnell Genome Institute) ;
Anand, Shankara (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Akiyama, Yo (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Liu, Wenke (NYU Grossman School of Medicine) ;
Wyczalkowski, Matthew A. (McDonnell Genome Institute) ;
Song, Yizhe (McDonnell Genome Institute) ;
Storrs, Erik P. (McDonnell Genome Institute) ;
Wendl, Michael C. (Washington University in St. Louis) ;
Zhang, Wubing (Dana-Farber Cancer Institute (Boston, Estats Units)) ;
Sibai, Mustafa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ruiz-Serra, Victoria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Liang, Wen-Wei (McDonnell Genome Institute) ;
Terekhanova, Nadezhda V. (McDonnell Genome Institute) ;
Martins Rodrigues, Fernanda (McDonnell Genome Institute) ;
Clauser, Karl R. (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Heiman, David I. (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Zhang, Qing (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Aguet, Francois (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Calinawan, Anna P. (Icahn School of Medicine at Mount Sinai) ;
Dhanasekaran, Saravana Mohan (University of Michigan) ;
Birger, Chet (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Satpathy, Shankha (Broad Institute of Massachusetts Institute of Technology and Harvard) ;
Zhou, Daniel Cui (McDonnell Genome Institute) ;
Wang, Liang-Bo (McDonnell Genome Institute) ;
Baral, Jessika (McDonnell Genome Institute) ;
Johnson, Jared L. (Weill Cornell Medicine) ;
Huntsman, Emily M. (Weill Cornell Medicine) ;
Pugliese, Pietro (University of Sannio (Benevento, Itàlia)) ;
Colaprico, Antonio (University of Miami Miller School of Medicine) ;
Iavarone, Antonio (University of Miami Miller School of Medicine) ;
Chheda, Milan G. (Washington University in St. Louis) ;
Ricketts, Christopher J. (National Institutes of Health) ;
Fenyö, David (NYU Grossman School of Medicine) ;
Payne, Samuel H. (Brigham Young University) ;
Rodriguez, Henry (Office of Cancer Clinical Proteomics Research) ;
Robles, Ana I. (Office of Cancer Clinical Proteomics Research) ;
Gillette, Michael A. (Harvard Medical School) ;
Kumar-Sinha, Chandan (University of Michigan) ;
Lazar, Alexander (The University of Texas MD Anderson Cancer Center) ;
Cantley, Lewis (Weill Cornell Medicine) ;
Getz, Gad A. (Harvard Medical School) ;
Ding, Li (Siteman Cancer Center) ;
An, Eunkyung ;
Anurag, Meenakshi ;
Bavarva, Jasmin ;
Birrer, Michael J. ;
Calinawan, Anna ;
Ceccarelli, Michele ;
Chan, Daniel W. ;
Chinnaiyan, Arul M. ;
Cho, Hanbyul ;
Chowdhury, Shrabanti ;
Cieslik, Marcin P. ;
da Veiga Leprevost, Felipe ;
Day, Corbin ;
Domagalski, Marcin J. ;
Dou, Yongchao ;
Druker, Brian J. ;
Edwards, Nathan ;
Ellis, Matthew J. ;
Selvan, Myvizhi Esai ;
Foltz, Steven M. ;
Francis, Alicia ;
Gonzalez Robles, Tania J. ;
Gosline, Sara J. C. ;
Gümüş, Zeynep H. ;
Hiltke, Tara ;
Hong, Runyu ;
Hostetter, Galen ;
Hu, Yingwei ;
Huang, Chen ;
Huntsman, Emily ;
Jaehnig, Eric J. ;
Jewel, Scott D. ;
Ji, Jiayi ;
Jiang, Wen ;
Katsnelson, Lizabeth ;
Ketchum, Karen A. ;
Kolodziejczak, Iga ;
Lei, Jonathan T. ;
Liao, Yuxing ;
Lindgren, Caleb M. ;
Liu, Tao ;
Ma, Weiping ;
McKerrow, Wilson ;
Nesvizhskii, Alexey I. ;
Newton, Chelsea ;
Oldroyd, Robert ;
Omenn, Gilbert S. ;
Paulovich, Amanda G. ;
Petralia, Francesca ;
Reva, Boris ;
Rodland, Karin D. ;
Ruggles, Kelly V. ;
Rykunov, Dmitry ;
Savage, Sara R. ;
Schadt, Eric E. ;
Schnaubelt, Michael ;
Schraink, Tobias ;
Shi, Zhiao ;
Smith, Richard D. ;
Song, Xiaoyu ;
Tan, Jimin ;
Thangudu, Ratna R. ;
Tignor, Nicole ;
Wang, Joshua M. ;
Wang, Pei ;
Wang, Ying Cindy ;
Wen, Bo ;
Wiznerowicz, Maciej ;
Yi, Xinpei ;
Zhang, Bing ;
Zhang, Hui ;
Zhang, Xu ;
Zhang, Zhen ;
Universitat Autònoma de Barcelona
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan-cancer analysis uncovers insights into the impacts of cancer drivers by identifying their significant cis-effects and distal trans-effects quantified at the RNA, protein, and phosphoprotein levels. [...]
2023 -  10.1016/j.cell.2023.07.014
Cell, Vol. 186 Núm. 18 (31 2023) , p. 3921-3944.e25
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812.9 KB |
Comparative genomics of Balto, a famous historic dog, captures lost diversity of 1920s sled dogs
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Moon, Katherine L. (University of California. Department of Ecology and Evolutionary Biology) ;
Huson, Heather J. (Cornell University College of Agriculture and Life Sciences. Department of Animal Sciences) ;
Morrill, Kathleen (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ;
Wang, Ming-Shan (University of California. Howard Hughes Medical Institute) ;
Li, Xue (Broad Institute of MIT and Harvard) ;
Srikanth, Krishnamoorthy (Cornell University College of Agriculture and Life Sciences. Department of Animal Sciences) ;
Lindblad-Toh, Kerstin (Uppsala University. Department of Medical Biochemistry & Microbiology) ;
Svenson, Gavin J. (Cleveland Museum of Natural History) ;
Karlsson, Elinor K. (University of Massachusetts Medical School. Bioinformatics and Integrative Biology) ;
Shapiro, Beth (University of California. Department of Ecology and Evolutionary Biology)
We reconstruct the phenotype of Balto, the heroic sled dog renowned for transporting diphtheria antitoxin to Nome, Alaska in 1925, using evolutionary constraint estimates from the Zoonomia alignment of 240 mammals and 682 genomes from dogs and wolves of the 21st century. [...]
2023 - 10.1126/science.abn5887
Science, Vol. 380 Num. 6643 (April 2023) , art. eabn5887
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3.
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Metagenomic analysis of antibiotic-resistance genes and viruses released from glaciers into downstream habitats
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Wang, Yan (Zhejiang University of Technology. College of Environment) ;
Xu, Nuohan (Zhejiang University of Technology. College of Environment) ;
Chen, Bingfeng (Zhejiang University of Technology. College of Environment) ;
Zhang, Zhenyan (Zhejiang University of Technology. College of Environment) ;
Lei, Chaotang (Zhejiang University of Technology. College of Environment) ;
Zhang, Qi (Zhejiang University of Technology. College of Environment) ;
Gu, Yanpeng (Zhejiang University of Technology. College of Environment) ;
Wang, Tingzhang (Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province) ;
Wang, Meixia (Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province) ;
Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Qian, Haifeng (Zhejiang University of Technology. College of Environment)
Glaciers serve as effective reservoirs of antibiotic resistance genes (ARGs) and viruses for millions of years. Climate change and anthropogenic activity have accelerated the melting of glaciers, but the patterns of release of ARGs and viruses from melting glaciers into downstream habitats remain unknown. [...]
2024 - 10.1016/j.scitotenv.2023.168310
Science of the total environment, Vol. 908 (Jan. 2024) , art. 168310
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4.
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Effects of livestock grazing on the relationships between soil microbial
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Xu, Hongwei (Sichuan Agricultural University) ;
You, Chengming (Sichuan Agricultural University) ;
Ton, Ba (Sichuan Agricultural University) ;
Xu, Lin (Sichuan Agricultural University) ;
Liu, Yang (Sichuan Agricultural University) ;
Wang, Minggang (Beijing Forestry University) ;
Xu, Zhenfeng (Sichuan Agricultural University) ;
Sardans i Galobart, Jordi (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Livestock grazing of grassland ecosystems may induce shifts in microbe community traits and soil carbon (C) cycling; however, impacts of grassland management (grazing) on soil C- microbe community trait (microbial biomass, diversity, community structure, and enzyme activity) relationships are unclear. [...]
2023 - 10.1016/j.scitotenv.2023.163416
Science of the total environment, Vol. 881 (July 2023) , art. 163416
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5.
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12 p, 1.3 MB |
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3) : a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery
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Marcucci, Maura (Population Health Research Institute) ;
Painter, Thomas W. (Department of Anaesthesia. Royal Adelaide Hospital) ;
Conen, David (Population Health Research Institute) ;
Leslie, Kate (Department of Critical Care Medicine. Melbourne Medical School. University of Melbourne) ;
Lomivorotov, Vladimir V. (Department of Anesthesiology and Intensive Care. Novosibirsk State University) ;
Sessler, Daniel (Department of Outcomes Research. Anesthesiology Institute. Cleveland Clinic) ;
Chan, Matthew T.V. (The Chinese University of Hong Kong) ;
Borges, Flavia K. (Population Health Research Institute) ;
Martinez-Zapata, Maria José (Institut d'Investigació Biomèdica Sant Pau) ;
Wang, C.Y. (Department of Anaesthesiology. Faculty of Medicine. University of Malaya) ;
Xavier, Denis (St. John's Medical College) ;
Ofori, Sandra N. (Population Health Research Institute) ;
Landoni, G. (School of Medicine. Vita-Salute San Raffaele University) ;
Efremov, S. (Saint Petersburg State University Hospital) ;
Kleinlugtenbelt, Y.V. (Department of Orthopedic and Trauma Surgery. Deventer Ziekenhuis) ;
Szczeklik, W. (Jagiellonian University Medical College. Center for Intensive Care and Perioperative Medicine) ;
Schmartz, D. (CHU Brugmann. Université libre de Bruxelles) ;
Garg, A. X. (Department of Medicine. Epidemiology and Biostatistics. Western University) ;
Short, T.G. (University of Auckland. School of Health Sciences) ;
Wittmann, M. (Department of Anesthesiology. University Hospital) ;
Meyhoff, C.S. (Department of Anaesthesia and Intensive Care. Bispebjerg and Frederiksberg Hospital. University of Copenhagen) ;
Amir, Mohammed (Shifa International Hospital (STMU)) ;
Torres, D. (Universidad de Los Andes) ;
Patel, A. (Department of Medicine. McMaster University) ;
Duceppe, E. (Department of Medicine. Universite de Montreal) ;
Ruetzler, K. (Department of Outcomes Research. Anesthesiology Institute. Cleveland Clinic) ;
Parlow, Joel (Department of Anesthesiology and Perioperative Medicine. Kingston General Hospital and Queen's University) ;
Tandon, V. (Department of Medicine. McMaster University) ;
Wang, M.K. (Population Health Research Institute) ;
Fleischmann, E. (Department of Anesthesia. General Intensive Care and Pain Management. Medical University of Vienna) ;
Polanczyk, C.A. (Cardiology Department. Hospital de Clínicas de Porto Alegre) ;
Jayaram, R. (Nuffield Department of Anaesthetics. Clinical Neurosciences. University of Oxford) ;
Astrakov, S.V. (Department of Anesthesiology. Novosibirsk State University) ;
Rao, M. (St. John's Medical College) ;
VanHelder, T. (Department of Anesthesia. McMaster University) ;
Wu, W.K.K. (The Chinese University of Hong Kong) ;
Cheong, C.C. (Department of Anaesthesiology. Faculty of Medicine. University of Malaya) ;
Ayad, S. (Case Western Reserve University. Anesthesiology Institute. Cleveland Clinic - Fairview Hospital) ;
Abubakirov, M. (Meshalkin National Medical Research Center) ;
Kirov, M. (Department of Anesthesiology and Intensive Care Medicine. Northern State Medical University) ;
Bhatt, Keyur (SIDS Hospital & Research Centre) ;
de Nadal, M. (Hospital Universitari Vall d'Hebron) ;
Likhvantsev, V. (M. Vladimirskiy Moscow Regional Clinical and Research Institute) ;
Paniagua, Pilar (Institut d'Investigació Biomèdica Sant Pau) ;
Aguado, H.J. (Trauma & Orthopaedic surgery department. Hospital Clínico Universitario) ;
McGillion, M. (School of Nursing. McMaster University) ;
Lamy, A. (Department of Surgery. McMaster University) ;
Whitlock, R.P. (Department of Surgery. McMaster University) ;
Roshanov, P. (Department of Medicine. London Health Sciences Centre) ;
Stillo, D. (Population Health Research Institute) ;
Copland, I. (Population Health Research Institute) ;
Vincent, J. (Population Health Research Institute) ;
Balasubramanian, K. (Population Health Research Institute) ;
Bangdiwala, S.I. (Population Health Research Institute) ;
Biccard, Bruce M (Department of Anaesthesia and Perioperative Medicine. Groote Schuur Hospital and University of Cape Town) ;
Kurz, A. (Department of General Anaesthesiology. Emergency- and Intensive Care Medicine. Medical University Graz) ;
Srinathan, S. (Department of Surgery. University of Manitoba) ;
Petit, S. (Population Health Research Institute) ;
Eikelboom, J. (Population Health Research Institute) ;
Richards, T. (Faculty of Health and Medical Sciences. University of Western Australia) ;
Gross, P.L. (Department of Medicine. McMaster University) ;
Alfonsi, P. (Department of Anesthesiology. GH Paris Saint Joseph) ;
Guyatt, G. (Department of Medicine. McMaster University) ;
Belley-Cote, E. (Population Health Research Institute) ;
Spence, J. (Department of Anesthesia. McMaster University) ;
McIntyre, W. (Population Health Research Institute) ;
Yusuf, S. (Population Health Research Institute) ;
Devereaux, P. J (Population Health Research Institute)
Background: For patients undergoing noncardiac surgery, bleeding and hypotension are frequent and associated with increased mortality and cardiovascular complications. Tranexamic acid (TXA) is an antifibrinolytic agent with the potential to reduce surgical bleeding; however, there is uncertainty about its efficacy and safety in noncardiac surgery. [...]
2022 - 10.1186/s13063-021-05992-1
Trials, Vol. 23 Núm. 1 (december 2022) , p. 101
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9 p, 318.7 KB |
Effect of a Perioperative Hypotension-Avoidance Strategy Versus a Hypertension-Avoidance Strategy on the Risk of Acute Kidney Injury : A Clinical Research Protocol for a Substudy of the POISE-3 Randomized Clinical Trial
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Garg, Amit X. (London Health Sciences Centre) ;
Cuerden, Meaghan (London Health Sciences Centre) ;
Aguado, Hector (Hospital Clínico Universitario de Valladolid) ;
Amir, Mohammed (Shifa International Hospital) ;
Belley-Cote, Emilie P. (McMaster University (Canadà)) ;
Bhatt, Keyur (SIDS Hospital Research Centre) ;
Biccard, Bruce M (Groote Schuur Hospital) ;
Borges, Flavia K. (Population Health Research Institute) ;
Chan, Matthew (The Chinese University of Hong Kong) ;
Conen, David (Population Health Research Institute) ;
Duceppe, Emmanuelle (Population Health Research Institute) ;
Efremov, Sergey (Saint Petersburg State University) ;
Eikelboom, John (McMaster University (Canadà)) ;
Fleischmann, Edith (Medical University of Vienna) ;
Giovanni, Landoni (Istituto Scientifico Universitario San Raffaele) ;
Gross, Peter (McMaster University (Canadà)) ;
Jayaram, Raja (University of Oxford) ;
Kirov, Mikhail (Northern State Medical University of the Ministry of Healthcare of the Russian Federation) ;
Kleinlugtenbelt, Ydo (Deventer Ziekenhuis) ;
Kurz, Andrea (Medical University of Graz) ;
Lamy, Andre (Population Health Research Institute) ;
Leslie, Kate (The Royal Melbourne Hospital) ;
Likhvantsev, Valery (I. M. Sechenov Moscow Medical Academy) ;
Lomivorotov, Vladimir (Novosibirsk State University) ;
Marcucci, Maura (McMaster University (Canadà)) ;
Martinez-Zapata, Maria José (Institut d'Investigació Biomèdica Sant Pau) ;
McGillion, Michael (McMaster University (Canadà)) ;
McIntyre, William (Population Health Research Institute) ;
Meyhoff, Christian (University of Copenhagen) ;
Ofori, Sandra (Population Health Research Institute) ;
Painter, Thomas (Royal Adelaide Hospital) ;
Paniagua, Pilar (Institut d'Investigació Biomèdica Sant Pau) ;
Parikh, Chirag (Johns Hopkins University) ;
Parlow, Joel (Kingston General Hospital) ;
Patel, Ameen (McMaster University (Canadà)) ;
Polanczyk, Carisi (Hospital de Clinicas de Porto Alegre) ;
Richards, Toby (The University of Western Australia) ;
Roshanov, Pavel (Western University) ;
Schmartz, Denis (CHU Brugmann) ;
Sessler, Daniel (Cleveland Clinic) ;
Short, Tim (Auckland District Health Board) ;
Sontrop, Jessica M. (Western University) ;
Spence, Jessica (McMaster University (Canadà)) ;
Srinathan, Sadeesh (University of Manitoba) ;
Stillo, David (Population Health Research Institute) ;
Szczeklik, Wojciech (Jagiellonian University) ;
Tandon, Vikas (McMaster University (Canadà)) ;
Torres, David (Clinica Santa Maria (Chile)) ;
Van Helder, Thomas (Hamilton Health Sciences) ;
Vincent, Jessica (Population Health Research Institute) ;
Wang, C.Y. (University of Malaya) ;
Wang, Michael (McMaster University (Canadà)) ;
Whitlock, Richard (Population Health Research Institute) ;
Wittmann, Maria (Universitätsklinikum Bonn) ;
Xavier, Denis (St. John's National Academy of Health Sciences) ;
Devereaux, P. J (McMaster University (Canadà))
Background: Most patients who take antihypertensive medications continue taking them on the morning of surgery and during the perioperative period. However, growing evidence suggests this practice may contribute to perioperative hypotension and a higher risk of complications. [...]
2022 - 10.1177/20543581211069225
Canadian Journal of Kidney Health and Disease, Vol. 9 (january 2022)
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18 p, 10.4 MB |
Vaccination against swine influenza in pigs causes different drift evolutionary patterns upon swine influenza virus experimental infection and reduces the likelihood of genomic reassortments
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López-Valiñas, Álvaro (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Valle González, Marta (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Wang, Miaomiao (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Darji, Ayub (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Chiapponi, Chiara (Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia-Romagna. WOAH Reference Laboratory for Swine Influenza) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Ganges, Llilianne (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Núñez, J. Ignacio (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Influenza A viruses (IAVs) can infect a wide variety of bird and mammal species. Their genome is characterized by 8 RNA single stranded segments. The low proofreading activity of their polymerases and the genomic reassortment between different IAVs subtypes allow them to continuously evolve, constituting a constant threat to human and animal health. [...]
2023 - 10.3389/fcimb.2023.1111143
Frontiers in cellular and infection microbiology, Vol. 13 (march 2023)
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8.
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184 p, 15.1 MB |
Electronic tongues based on electropolymerized molecularly imprinted polymers for pharmaceutical analysis
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Wang, Mingyue ;
Cetó Alsedà, Xavier, dir. ;
Valle Zafra, Manuel del, dir.
En les darreres dècades, atès que el creixent ús de fàrmacs pel tractament de diverses malalties contribueix a la millora progressiva de la qualitat de vida de l'ésser humà, l'anàlisi farmacèutica s'ha considerat un afer important que presenta una gran demanda en diversos camps, com la indústria farmacèutica, el control clínic i la protecció del medi ambient. [...]
En las últimas décadas, dado que el creciente uso de fármacos para el tratamiento de diversas enfermedades contribuye a la progresiva mejora de la calidad de vida del ser humano, el análisis farmacéutico se ha considerado una cuestión importante que presenta una gran demanda en varios campos, como la industria farmacéutica, el control clínico y la protección del medio ambiente. [...]
In the past decades, as the increasing use of drugs for treating various diseases contributed to the progressively improved life quality of human being, pharmaceutical analysis has been regarded as an important issue that is demanded in several fields, such as pharmaceutical industry, clinical monitoring, and environmental protection. [...]
2022
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9.
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8 p, 4.2 MB |
A Sensor Array Based on Molecularly Imprinted Polymers and Machine Learning for the Analysis of Fluoroquinolone Antibiotics
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Wang, Mingyue (Universitat Autònoma de Barcelona. Departament de Química) ;
Cetó Alsedà, Xavier (Universitat Autònoma de Barcelona. Departament de Química) ;
Valle Zafra, Manuel del (Universitat Autònoma de Barcelona. Departament de Química)
Fluoroquinolones (FQs) are one of the most important types of antibiotics in the clinical, poultry, and aquaculture industries, and their monitoring is required as the abuse has led to severe issues, such as antibiotic residues and antimicrobial resistance. [...]
2022 - 10.1021/acssensors.2c01260
ACS Sensors, Vol. 7, Issue 11 (October 2022) , p. 3318-3325
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10.
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16 p, 2.6 MB |
The FlagT4G Vaccine Confers a Strong and Regulated Immunity and Early Virological Protection against Classical Swine Fever
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Bohórquez Garzón, José Alejandro (University of Illinois at Urbana-Champaign. Veterinary Diagnostic Laboratory) ;
Wang, Miaomiao (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Díaz, Ivan (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Alberch, Mònica (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pérez-Simó, Marta (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Rosell, Rosa (Generalitat de Catalunya. Departament d'Acció Climàtica, Alimentació i Agenda Rural) ;
Gladue, Douglas P. (Plum Island Animal Disease Center) ;
Borca, Manuel V. (Plum Island Animal Disease Center) ;
Ganges, Llilianne (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Control of classical swine fever virus (CSFV) in endemic countries relies on vaccination, mostly using vaccines that do not allow for differentiation of vaccinated from infected animals (DIVA). FlagT4G vaccine is a novel candidate that confers robust immunity and shows DIVA capabilities. [...]
2022 - 10.3390/v14091954
Viruses, Vol. 14 (september 2022)
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