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Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
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Couch, Fergus J. (Mayo Clinic) ;
Kuchenbaecker, Karoline B. (University of Cambridge) ;
Michailidou, Kyriaki (University of Cambridge) ;
Mendoza-Fandino, Gustavo A. (H. Lee Moffitt Cancer Center and Research Institute) ;
Nord, Silje (Oslo University Hospital (Oslo, Noruega)) ;
Lilyquist, Janna (Mayo Clinic) ;
Olswold, Curtis (Mayo Clinic) ;
Hallberg, Emily (Mayo Clinic) ;
Agata, Simona (Istituto Oncologico Veneto IOV-IRCCS) ;
Ahsan, Habibul (The University of Chicago) ;
Aittomäki, Kristiina (Helsinki University Central Hospital) ;
Ambrosone, Christine B (Roswell Park Cancer Institute) ;
Andrulis, Irene L. (University of Toronto) ;
Anton-Culver, Hoda (University of California Irvine) ;
Arndt, Volker (German Cancer Research Center) ;
Arun, Banu K. (University of Texas MD Anderson Cancer Center) ;
Arver, Brita (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Barile, Monica (Istituto Europeo di Oncologia) ;
Barkardottir, Rosa B. (Landspitali University Hospital (Islàndia)) ;
Barrowdale, Daniel (University of Cambridge) ;
Beckmann, Lars (Institute for Quality and Efficiency in Health Care) ;
Beckmann, Matthias W. (University Breast Center Franconia) ;
Benitez, Javier (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Blank, Stephanie V. (New York University School of Medicine) ;
Blomqvist, Carl (University of Helsinki and Helsinki University Central Hospital) ;
Bogdanova, Natalia V. (Hannover Medical School) ;
Bojesen, Stig E. (Copenhagen University Hospital) ;
Bolla, Manjeet K. (University of Cambridge) ;
Bonanni, Bernardo (Istituto Europeo di Oncologia) ;
Brauch, Hiltrud (University of Tübingen) ;
Brenner, Hermann (German Cancer Research Center and National Center for Tumor Diseases) ;
Burwinkel, Barbara (University of Heidelberg) ;
Buys, Saundra (University of Utah School of Medicine) ;
Caldes, Trinidad (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Caligo, Maria (University Hospital of Pisa (Pisa, Itàlia)) ;
Canzian, Federico (German Cancer Research Center) ;
Carpenter, Jane (University of Sydney) ;
Chang-Claude, Jenny (German Cancer Research Center) ;
Chanock, Stephen (Centro Nacional de Investigaciones Oncológicas) ;
Chung, Wendy (Columbia University) ;
Claes, Kathleen (Ghent University) ;
Cox, Angela (University of Sheffield) ;
Cross, Simon S. (University of Sheffield) ;
Cunningham, Julie M. (Mayo Clinic) ;
Czene, Kamila (Karolinska Institutet (Estocolm, Suècia)) ;
Daly, Mary B. (Fox Chase Cancer Center) ;
Damiola, Francesca (Université Lyon) ;
Darabi, Hatef (Karolinska Institutet (Estocolm, Suècia)) ;
De la Hoya, Miguel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Devilee, Peter (Leiden University Medical Center) ;
Diez, Orland (Vall d'Hebron Institut d'Oncologia) ;
Ding, Yuan C. (Beckman Research Institute of City of Hope (Duarte, Estats Units d'Amèrica)) ;
Dolcetti, Riccardo (CRO Aviano National Cancer Institute) ;
Domchek, Susan M. (University of Pennsylvania) ;
Dorfling, Cecilia M. (University of Pretoria) ;
dos-Santos-Silva, Isabel (London School of Hygiene and Tropical Medicine) ;
Dumont, Martine (Laval University) ;
Dunning, Alison M. (University of Cambridge) ;
Eccles, Diana M. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Ehrencrona, Hans (Lund University Hospital) ;
Ekici, Arif B. (Comprehensive Cancer Center -EMN) ;
Eliassen, Heather (Harvard School of Public Health) ;
Ellis, Steve (University of Cambridge) ;
Fasching, Peter A. (University Breast Center Franconia) ;
Figueroa, Jonine (National Cancer Institute) ;
Flesch-Janys, Dieter (University Clinic Hamburg-Eppendorf) ;
Försti, Asta (Lund University) ;
Fostira, Florentia (Memokritos', Aghia Paraskevi Attikis) ;
Foulkes, William D. (McGill University) ;
Friebel, Tara (University of) ;
Friedman, Eitan (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ;
Frost, Debra (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ;
Gabrielson, Marike (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ;
Gammon, Marilie D. (Department of Epidemiology, University of) ;
Ganz, Patricia A. (UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center) ;
Gapstur, Susan M. (Epidemiology Research Program, American Cancer Society) ;
Garber, Judy (Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute) ;
Gaudet, Mia M. (Epidemiology Research Program, American Cancer Society) ;
Gayther, Simon A. (Department of Biomedical Sciences, Cedars Sinai Medical Center) ;
Gerdes, Anne-Marie (Copenhagen University Hospital Rigshospitalet) ;
Ghoussaini, Maya (University of Cambridge) ;
Giles, Graham G. (Cancer Council Victoria) ;
Glendon, Gord (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ;
Godwin, Andrew K. (University of Kansas Medical Center) ;
Goldberg, Mark S. (Royal Victoria Hospital) ;
Goldgar, David E. (University of Utah School of Medicine) ;
González-Neira, Anna (Centro Nacional de Investigaciones Oncológicas) ;
Greene, Mark H. (Clinical Genetics Branch) ;
Gronwald, Jacek (Pomeranian Medical University) ;
Guénel, Pascal (Inserm (National Institute of Health and Medical Research)) ;
Gunter, Marc (Imperial College London) ;
Haeberle, Lothar (University Breast Center Franconia) ;
Haiman, Christopher A. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ;
Hamann, Ute (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ;
Hansen, Thomas V. O. (Copenhagen University Hospital Rigshospitalet) ;
Hart, Steven (Department of Health Sciences Research, Mayo Clinic) ;
Healey, Sue (Department of Genetics, QIMR Berghofer Medical Research Institute) ;
Heikkinen, Tuomas (Helsinki University Central Hospital) ;
Henderson, Brian E. (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ;
Herzog, Josef (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ;
Hogervorst, Frans B. L. (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ;
Hollestelle, Antoinette (Department of Medical Oncology, Erasmus MC Cancer Institute) ;
Hooning, Maartje J. (Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center) ;
Hoover, Robert (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ;
Hopper, John L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ;
Humphreys, Keith (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ;
Hunter, David J. (Program in Molecular and Genetic Epidemiology, Harvard School of Public Health) ;
Huzarski, Tomasz (Department of Genetics and Pathology, Pomeranian Medical University) ;
Imyanitov, Evgeny N. (N.N. Petrov Institute of Oncology) ;
Isaacs, Claudine (Lombardi Comprehensive Cancer Center, Georgetown University) ;
Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University) ;
James, Paul (Department of Oncology, The University of Melbourne) ;
Janavicius, Ramunas (State Research Institute Centre for Innovative Medicine) ;
Jensen, Uffe Birk (Aarhus University Hospital (Aarhus, Dinamarca)) ;
John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California) ;
Jones, Michael (Division of Genetics and Epidemiology, Institute of Cancer Research) ;
Kabisch, Maria (Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)) ;
Kar, Siddhartha (Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge) ;
Karlan, Beth Y. (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
Khan, Sofia (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ;
Khaw, Kay-Tee (Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory) ;
Kibriya, Muhammad G. (Department of Health Studies, The University of Chicago) ;
Knight, Julia A. (Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital) ;
Ko, Yon-Dschun (Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus) ;
Konstantopoulou, Irene (Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ;
Kosma, Veli-Matti (School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ;
Kristensen, Vessela (Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet) ;
Kwong, Ava (Department of Surgery, The University of Hong Kong) ;
Laitman, Yael (Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center) ;
Lambrechts, Diether (Vesalius Research Center, VIB) ;
Lazaro, Conxi (Institut Català d'Oncologia) ;
Lee, Eunjung (Department of Preventive Medicine, University of Southern California) ;
Le Marchand, Loic (Cancer Epidemiology Program, University of Cancer Center) ;
Lester, Jenny (Cedars Sinai Heart Institute (Los Angeles, Estats Units d'Amèrica)) ;
Lindblom, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Molecular Medicine and Surgery) ;
Lindor, Noralane (Health Sciences Research, Mayo Clinic) ;
Lindstrom, Sara (Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health) ;
Liu, Jianjun (Human Genetics Division, Genome Institute of Singapore) ;
Long, Jirong (Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ;
Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University) ;
Mai, Phuong L. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ;
Makalic, Enes (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ;
Malone, Kathleen E. (Department of Epidemiology, School of Public Health and Community Medicine, University of Washington) ;
Mannermaa, Arto (School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland) ;
Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ;
Margolin, Sara (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Marme, Frederik (Department of Obstetrics and Gynecology, University of Heidelberg) ;
Martens, John W. M. (Department of Medical Oncology, Erasmus MC Cancer Institute) ;
McGuffog, Lesley (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ;
Meindl, Alfons (Department of Gynaecology and Obstetrics, Technical University of Munich) ;
Miller, Austin (NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute) ;
Milne, Roger L. (Cancer Epidemiology Centre (Melbourne, Austràlia)) ;
Miron, Penelope (Department of Genomics and Genome Sciences, Case Western Reserve University Medical School) ;
Montagna, Marco (Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS) ;
Mazoyer, Sylvie (INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon) ;
Mulligan, Anna M. (Department of Laboratory Medicine and Pathobiology, University of Toronto) ;
Muranen, Taru A. (Helsinki University Central Hospital) ;
Nathanson, Katherine L. (Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania) ;
Neuhausen, Susan L. (Department of Population Sciences, Beckman Research Institute of City of Hope) ;
Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital) ;
Nordestgaard, Børge G. (Copenhagen University Hospital) ;
Nussbaum, Robert L. (Invitae Corporation) ;
Offit, Kenneth (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ;
Olah, Edith (Department of Molecular Genetics, National Institute of Oncology) ;
Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center) ;
Olson, Janet E. (Department of Health Sciences Research, Mayo Clinic) ;
Osorio, Ana (Centro Nacional de Investigaciones Oncológicas) ;
Park, Sue K. (Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University) ;
Peeters, Petra H. (MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London) ;
Peissel, Bernard (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ;
Peterlongo, Paolo (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare) ;
Peto, Julian (Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine) ;
Phelan, Catherine M. (Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute) ;
Pilarski, Robert (Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University) ;
Poppe, Bruce (Center for Medical Genetics, Ghent University) ;
Pylkäs, Katri (Oulu University Hospital (Finlàndia)) ;
Radice, Paolo (Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT)) ;
Rahman, Nazneen (Section of Cancer Genetics, Institute of Cancer Research) ;
Rantala, Johanna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Rappaport, Christine (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ;
Rennert, Gad (Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine) ;
Richardson, Andrea (Department of Pathology, Johns Hopkins University School of Medicine) ;
Robson, Mark (Department of Medicine, Memorial Sloan-Kettering Cancer Center) ;
Romieu, Isabelle (International Agency for Research on Cancer) ;
Rudolph, Anja (Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)) ;
Rutgers, Emiel J. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ;
Sanchez, Maria-Jose (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Santella, Regina M. (Department of Environmental Health Sciences, Columbia University) ;
Sawyer, Elinor J. (Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital) ;
Schmidt, Daniel F. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne) ;
Schmidt, Marjanka K. (Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital) ;
Schmutzler, Rita K. (Center for Molecular Medicine Cologne (CMMC), University of Cologne) ;
Schumacher, Fredrick (Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center) ;
Scott, Rodney (Division of Genetics, Hunter Area Pathology Service, John Hunter Hospital) ;
Senter, Leigha (Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University) ;
Sharma, Priyanka (Department of Hematology and Oncology, University of Kansas Medical Center) ;
Simard, Jacques (Centre Hospitalier Universitaire de Québec Research Center, Laval University) ;
Singer, Christian F. (Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna) ;
Sinilnikova, Olga M. (Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon-Centre Léon Bérard) ;
Soucy, Penny (Centre Hospitalier Universitaire de Québec Research Center, Laval University) ;
Southey, Melissa (Department of Pathology, The University of Melbourne) ;
Steinemann, Doris (Hannover Medical School) ;
Stenmark-Askmalm, Marie (Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University) ;
Stoppa-Lyonnet, Dominique (Université Paris Descartes) ;
Swerdlow, Anthony (Division of Genetics and Epidemiology, Institute of Cancer Research) ;
Szabo, Csilla I. (National Human Genome Research Institute, National Institutes of Health) ;
Tamimi, Rulla (Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health) ;
Tapper, William (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Teixeira, Manuel R. (Biomedical Sciences Institute (ICBAS), Porto University) ;
Teo, Soo-Hwang (University Malaya Cancer Research Institute, Faculty of Medicine, University Malaya Medical Centre, University Malaya) ;
Terry, Mary Beth (Department of Epidemiology, Mailman School of Public Health, Columbia University) ;
Thomassen, Mads (Odense University Hospital (Dinamarca)) ;
Thompson, Deborah (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ;
Tihomirova, Laima (Latvian Biomedical Research and Study Centre) ;
Toland, Amanda E. (Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University) ;
Tollenaar, Robert A. E. M. (Department of Surgical Oncology, Leiden University Medical Center) ;
Tomlinson, Ian (Wellcome Trust Centre for Human Genetics (Oxford, Regne Unit)) ;
Truong, Thérèse (Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer) ;
Tsimiklis, Helen (Department of Pathology, The University of Melbourne) ;
Teulé, Alex (Institut d'Investigació Biomèdica de Bellvitge) ;
Tumino, Rosario (Cancer Registry and Histopathology Unit, 'Civic-M.P. Arezzo' Hospital) ;
Tung, Nadine (Department of Medical Oncology, Beth Israel Deaconess Medical Center) ;
Turnbull, Clare (Section of Cancer Genetics, Institute of Cancer Research) ;
Ursin, Giski (Cancer Registry of Norway, Institute of Population-Based Cancer Research) ;
van Deurzen, Carolien H. M. (Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center) ;
van Rensburg, Elizabeth J. (Department of Genetics, University of Pretoria) ;
Varon-Mateeva, Raymonda (Institute of Human Genetics, Charite Berlin) ;
Wang, Zhaoming (Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute) ;
Wang-Gohrke, Shan (University Hospital of Ulm (Alemanya)) ;
Weiderpass, Elisabete (Genetic Epidemiology Group, Folkhälsan Research Center) ;
Weitzel, Jeffrey N. (Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network) ;
Whittemore, Alice (Department of Health Research and Policy-Epidemiology, Stanford University School of Medicine) ;
Wildiers, Hans (Multidisciplinary Breast Center, Department of General Medical Oncology, University Hospitals) ;
Winqvist, Robert (Oulu University Hospital (Finlàndia)) ;
Yang, Xiaohong R. (Division of Cancer Epidemiology and Genetics, National Cancer Institute) ;
Yannoukakos, Drakoulis (Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis) ;
Yao, Song (Department of Cancer Prevention and Control, Roswell Park Cancer Institute) ;
Zamora, M. Pilar (Hospital Universitario La Paz (Madrid)) ;
Zheng, Wei (Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine) ;
Hall, Per (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ;
Kraft, Peter (Department of Biostatistics, Harvard School Of Public Health) ;
Vachon, Celine (Department of Health Sciences Research, Mayo Clinic) ;
Slager, Susan (Department of Health Sciences Research, Mayo Clinic) ;
Chenevix-Trench, Georgia (Cancer Division, QIMR Berghofer Medical Research Institute) ;
Pharoah, Paul D. P. (Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge) ;
Monteiro, Alvaro A. N. (Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute) ;
García-Closas, Montserrat (Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health) ;
Easton, Douglas F. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ;
Antoniou, Antonis C. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge) ;
Universitat Autònoma de Barcelona
Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P <5 × 10 −8) with oestrogen receptor (ER)-negative breast cancer and BRCA1 -associated breast cancer risk. [...]
2016 -  10.1038/ncomms11375
Nature communications, Vol. 7 (04 2016)
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Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer
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Klein, Alison P. (Johns Hopkins School of Medicine, Baltimore, USA) ;
Wolpin, Brian M. (Dana-Farber Cancer Institute, Boston, USA) ;
Risch, Harvey A. (Yale School of Public Health, New Haven, USA) ;
Stolzenberg-Solomon, Rachael Z. (National Institutes of Health, Bethesda, USA) ;
Mocci, Evelina (Johns Hopkins School of Medicine, Baltimore, USA) ;
Zhang, Mingfeng (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Canzian, Federico (Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Childs, Erica J. (Johns Hopkins School of Medicine, Baltimore, USA) ;
Hoskins, Jason W. (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Jermusyk, Ashley (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Zhong, Jun (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Chen, Fei (Johns Hopkins School of Medicine, Baltimore, USA) ;
Albanes, Demetrius (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Andreotti, Gabriella (National Institutes of Health, Bethesda, USA) ;
Arslan, Alan A. (New York University School of Medicine, New York, USA) ;
Babic, Ana (Dana-Farber Cancer Institute, Boston, USA) ;
Bamlet, William R. (Mayo Clinic College of Medicine, Rochester, USA) ;
Beane-Freeman, Laura (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
Berndt, Sonja (National Institutes of Health, Bethesda, USA) ;
Blackford, Amanda (Johns Hopkins School of Medicine, Baltimore, USA) ;
Borges, Michael (Johns Hopkins School of Medicine, Baltimore, USA) ;
Borgida, Ayelet (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, M5G 1×5, Canada.) ;
Bracci, Paige M. (University of California, San Francisco, USA) ;
Brais, Lauren (Dana-Farber Cancer Institute, Boston, USA) ;
Brennan, Paul (International Agency for Research on Cancer (IARC), Lyon, France) ;
Brenner, Hermann (Division of Preventive Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Bueno-de-Mesquita, Bas (National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands) ;
Buring, Julie (Division of Preventive Medicine, Brigham and Women's Hospital, Boston) ;
Campa, Daniele (University of Pisa) ;
Capurso, Gabriele (University of Rome) ;
Cavestro, Giulia Martina (Vita-Salute San Raffaele University, Milan) ;
Chaffee, Kari G (Mayo Clinic College of Medicine, Rochester, USA) ;
Chung, Charles C. (National Institutes of Health, Bethesda, USA) ;
Cleary, Sean (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ;
Cotterchio, Michelle (University of Toronto.) ;
Dijk, Frederike (University of Amsterdam. Department of Pathology, Academic Medical Center) ;
Duell, Eric J. (Institut d'Investigació Biomèdica de Bellvitge) ;
Foretova, Lenka (Masaryk Memorial Cancer Institute. Department of Cancer Epidemiology and Genetics, Brno, Czech Republic.) ;
Fuchs, Charles (Yale Cancer Center, New Haven, USA) ;
Funel, Niccola (University of Pisa.) ;
Gallinger, Steven (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ;
M. Gaziano, J. Michael (Boston VA Healthcare System) ;
Gazouli, Maria (National and Kapodistrian University of Athens) ;
Giles, Graham G. (Monash University. Department of Epidemiology and Preventive Medicine, Melbourne, Australia) ;
Giovannucci, Edward (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Goggins, Michael (Johns Hopkins School of Medicine. Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Baltimore) ;
Goodman, Gary E. (Fred Hutchinson Cancer Research Center. Division of Public Health Sciences, Seattle, USA) ;
Goodman, Phyllis J. (Fred Hutchinson Cancer Research Center. SWOG Statistical Center, Seattle, USA) ;
Hackert, Thilo (University Hospital Heidelberg, Germany) ;
Haiman, Christopher A (University of Southern California, USA) ;
Hartge, Patricia (National Institutes of Health, Bethesda, USA) ;
Hasan, Manal (University of Texas MD Anderson Cancer Center, USA) ;
Hegyi, Peter (University of Szeged, Szeged, Hungary) ;
Helzlsouer, Kathy J. (National Institutes of Health, Bethesda, USA) ;
Herman, Joseph (Johns Hopkins School of Medicine. Baltimore, USA) ;
Holcatova, Ivana (Charles University, Prague, Czech Republic) ;
Holly, Elizabeth A. (University of California, San Francisco) ;
Hoover, Robert (National Institutes of Health, Bethesda, USA) ;
Hung, Rayjean J. (Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Canada) ;
Jacobs, Eric J. (American Cancer Society. Epidemiology Research Program, Atlanta) ;
Jamroziak, Krzysztof (Institute of Hematology and Transfusion Medicine, Warsaw, Poland) ;
Janout, Vladimir (Faculty of Medicine, University of Olomouc, Czech Republic) ;
Kaaks, Rudolf (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Khaw, Kay-Tee (University of Cambridge) ;
Klein, Eric A. (Cleveland Clinic) ;
Kogevinas, M (Hospital del Mar (Barcelona, Catalunya)) ;
Kooperberg, Charles (Fred Hutchinson Cancer Research Center, Seattle) ;
Kulke, Matthew H. (Dana-Farber Cancer Institute, Boston) ;
Kupcinskas, Juozas (Lithuanian University of Health Sciences, Kaunas, Lithuania) ;
Kurtz, Robert J. (Memorial Sloan Kettering Cancer Center, New York, USA) ;
Laheru, Daniel (Johns Hopkins School of Medicine, Baltimore, USA) ;
Landi, Stefano (University of Pisa) ;
Lawlor, Rita T. (University and Hospital Trust of Verona) ;
Lee, I.-Min (Harvard School of Public Health, Boston) ;
LeMarchand, Loic (University of Hawaii Cancer Center, Honolulu, USA) ;
Lu, Lingeng (Yale School of Public Health, New Haven, USA) ;
Malats, Núria (Centro de Investigación Biomédica en Red de Cáncer, Madrid) ;
Mambrini, Andrea (Oncology Department, ASL1 Massa Carrara, Italy) ;
Mannisto, Satu (National Institute for Health and Welfare, Helsinki, Finland) ;
Milne, Roger L. (The University of Melbourne, Australia) ;
Mohelníková-Duchoňová, Beatrice (Palacky University Olomouc and University Hospital, Czech Republic) ;
Neale, Rachel E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Neoptolemos, John P. (University of Heidelburg, Heidelberg, Germany) ;
Oberg, Ann L. (Mayo Clinic College of Medicine, Rochester, USA) ;
Olson, Sara H. (Memorial Sloan Kettering Cancer Center, New York, USA) ;
Orlow, Irene (Memorial Sloan Kettering Cancer Center, New York, USA) ;
Pasquali, Claudio (University of Padua, Italy) ;
Patel, Alpa V. (American Cancer Society, Atlanta) ;
Peters, Ulrike (Fred Hutchinson Cancer Research Center, Seattle) ;
Pezzilli, Raffaele (Sant'Orsola-Malpighi Hospital, Bologna, Italy) ;
Porta, Miquel 1957- (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Real, Francisco X. (Universitat Pompeu Fabra) ;
Rothman, Nathaniel (National Institutes of Health, Bethesda, USA) ;
Scelo, Ghislaine (International Agency for Research on Cancer (IARC), Lyon, France) ;
Sesso, Howard D. (Harvard T.H. Chan School of Public Health. Department of Epidemiology) ;
Severi, Gianluca (Université Paris-Saclay, France) ;
Shu, Xiao-Ou (Vanderbilt University School of Medicine, Nashville, USA) ;
Silverman, Debra (National Institutes of Health, Bethesda, USA) ;
Smith, Jill P. (Georgetown University, Washington, USA) ;
Soucek, Pavel (Charles University, Pilsen, Czech Republic.) ;
Sund, Malin (Umeå University, Sweden) ;
Talar-Wojnarowska, Renata (Medical University of Łodz, Poland) ;
Tavano, Francesca (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS), Italy) ;
Thornquist, Mark D. (Fred Hutchinson Cancer Research Center, Seattle) ;
Tobias, Geoffrey S. (National Institutes of Health, Bethesda, USA) ;
Van Den Eeden, Stephen K. (Kaiser Permanente Northern California, USA) ;
Vashist, Yogesh (University Hamburg-Eppendorf, Germany) ;
Visvanathan, Kala (Johns Hopkins Bloomberg School of Public Health, Baltimore, USA) ;
Vodicka, Pavel (Academy of Sciences of the Czech Republic, Prague, Czech Republic) ;
Wactawski-Wende, Jean (University at Buffalo, USA) ;
Wang, Zhaoming (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ;
Wentzensen, Nicolas (National Cancer Institute, National Institutes of Health, Bethesda, USA) ;
White, Emily (University of Washington, USA) ;
Yu, Herbert (University of Hawaii Cancer Center, USA) ;
Yu, Kai (National Institutes of Health, Bethesda, USA) ;
Zeleniuch-Jacquotte, Anne (New York University School of Medicine, USA) ;
Zheng, Wei (Vanderbilt University School of Medicine, Nashville, USA) ;
Kraft, Peter (Harvard School of Public Health, USA) ;
Li, Donghui (University of Texas MD Anderson Cancer Center, USA) ;
Chanock, Stephen (National Institutes of Health, Bethesda, USA) ;
Obazee, Ofure (German Cancer Research Center (DKFZ), Heidelberg, Germany) ;
Petersen, Gloria M. (Mayo Clinic College of Medicine, Rochester, USA) ;
Amundadottir, Laufey T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica))
In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe and the United States combined. To identify common susceptibility alleles, we performed the largest pancreatic cancer GWAS to date, including 9040 patients and 12,496 controls of European ancestry from the Pancreatic Cancer Cohort Consortium (PanScan) and the Pancreatic Cancer Case-Control Consortium (PanC4). [...]
2018 - 10.1038/s41467-018-02942-5
Nature communications, Vol. 9 (february 2018)
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Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21
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Zhang, Mingfeng (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Wang, Zhaoming (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ;
Obazee, Ofure (German Cancer Research Center (DKFZ)) ;
Jia, Jinping (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Childs, Erica J. (Johns Hopkins School of Medicine. Department of Oncology) ;
Hoskins, Jason (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Figlioli, Gisella (German Cancer Research Center (DKFZ)) ;
Mocci, Evelina (Johns Hopkins School of Medicine. Department of Oncology) ;
Collins, Irene (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Chung, Charles C. (Frederick National Laboratory for Cancer Research (Frederick, Estats Units d'Amèrica)) ;
Hautman, Christopher (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Arslan, Alan A. (New York University Cancer Institute, New York, New York, USA) ;
Beane-Freeman, Laura (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Bracci, Paige M. (University of California San Francisco. Department of Epidemiology and Biostatistics) ;
Buring, Julie (Harvard Medical School) ;
Duell, Eric J. (Institut d'Investigació Biomèdica de Bellvitge) ;
Gallinger, Steven (Mount Sinai Hospital (Toronto, Canadà)) ;
Giles, Graham G. (Monash University (Melbourne, Austràlia). Department of Epidemiology and Preventive Medicine) ;
Goodman, Gary E. (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ;
Goodman, Phyllis J. (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ;
Kamineni, Aruna (Group Health Research Institute, Seattle, Washington, USA) ;
Kolonel, Laurence N. (University of Hawaii Cancer Center. Cancer Epidemiology Program) ;
Kulke, Matthew H. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Department of Medical Oncology) ;
Malats, Núria (Centro Nacional de Investigaciones Oncológicas) ;
Olson, Sara H. (Memorial Sloan Kettering Cancer Center) ;
Sesso, Howard D. (Harvard Medical School) ;
Visvanathan, Kala (Johns Hopkins Bloomberg School of Public Health) ;
White, Emily (University of Washington. Department of Epidemiology) ;
Zheng, Wei (Vanderbilt University Medical Center (Nashville, Estats Units d'Amèrica)) ;
Abnet, Christian C. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Albanes, Demetrius (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Andreotti, Gabriella (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Brais, Lauren (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Department of Medical Oncology) ;
Bueno-de-Mesquita, H. Bas (University of Malaya (Kuala Lumpur, Malàisia). Department of Social & Preventive Medicine) ;
Basso, Daniela (University Hospital of Padova (Pàdua, Itàlia)) ;
Berndt, Sonja (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Boutron-Ruault, Marie-Christine (IGR, F-94805, Villejuif, France) ;
Bijlsma, Maarten F. (University of Amsterdam. Laboratory for Experimental Oncology and Radiobiology) ;
Brenner, Hermann (German Cancer Research Center (DKFZ)) ;
Burdette, Laurie (Frederick National Laboratory for Cancer Research (Frederick, Estats Units d'Amèrica)) ;
Campa, Daniele (University of Pisa (Itàlia). Department of Biology) ;
Caporaso, Neil E. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Capurso, Gabriele ('Sapienza' University of Rome. Digestive and Liver Disease Unit) ;
Cavestro, Giulia Martina (Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy) ;
Cotterchio, Michelle (University of Toronto. Dalla Lana School of Public Health) ;
Costello, Eithne (University of Liverpool. Liverpool Pancreas Biomedical Research Unit) ;
Elena, Joanne (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Boggi, Ugo (University Hospital of Pisa (Pisa, Itàlia)) ;
Gaziano, J. Michael (Massachusetts Veteran's Epidemiology, Research, and Information Center, Geriatric Research Education and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, Massachusetts, USA) ;
Gazouli, Maria (Department of Basic Medical Sciences, Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, Athens, Greece) ;
Giovannucci, Edward L. (Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA) ;
Goggins, Michael (Johns Hopkins University. Department of Oncology) ;
Gross, Myron (Laboratory of Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA) ;
Haiman, Christopher A. (Preventive Medicine, University of Southern California, Los Angeles, California, USA) ;
Hassan, Manal (Department of Gastrointestinal Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA) ;
Helzlsouer, Kathy J. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Hu, Nan (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Hunter, David J. (Harvard Medical School, Boston, Massachusetts, USA) ;
Iskierka-Jazdzewska, Elzbieta (Department of Hematology, Medical University of Łodz, Łodz, Poland) ;
Jenab, Mazda (International Agency for Research on Cancer (IARC), Lyon, France) ;
Kaaks, Rudolf (German Cancer Research Center (DKFZ)) ;
Key, Timothy J. (Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom) ;
Khaw, Kay-Tee (School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom) ;
Klein, Eric A. (Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA) ;
Kogevinas, M.. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Krogh, Vittorio (Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy) ;
Kupcinskas, Juozas (Department of Gastroenterology, Lithuanian University of Health Sciences, Kaunas, Lithuania) ;
Kurtz, Robert C. (Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA) ;
Landi, Maria T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Landi, Stefano (Department of Biology, University of Pisa, Pisa, Italy) ;
Marchand, Le Loic (Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA) ;
Mambrini, Andrea (Oncology Department, ASL1 Massa Carrara, Massa Carrara, Italy) ;
Mannisto, Satu (National Institute for Health and Welfare, Department of Chronic Disease Prevention, Helsinki, Finland) ;
Milne, Roger L. (Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia) ;
Neale, Rachel E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Oberg, Ann L. (Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA) ;
Panico, Salvatore (Dipartimento di Medicina Clinica E Chirurgia, Federico II Univeristy, Naples, Italy) ;
Patel, Alpa V. (Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA) ;
Peeters, Petra H. M. (Imperial College London. Department of Epidemiology and Biostatistics) ;
Peters, Ulrike (Department of Epidemiology, University of Washington, Seattle, Washington, USA) ;
Pezzilli, Raffaele (Pancreas Unit, Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, Bologna, Italy) ;
Porta, Miquel 1957- (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Purdue, Mark (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Quiros, J. Ramón (Public Health and Participation Directorate, Asturias, Spain) ;
Riboli, Elio (Imperial College London. Department of Epidemiology and Biostatistics) ;
Rothman, Nathaniel (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Scarpa, Aldo (University and Hospital Trust of Verona. ARC-Net Centre for Applied Research on Cancer) ;
Scelo, Ghislaine (International Agency for Research on Cancer (IARC), Lyon, France) ;
Shu, Xiao-Ou (Vanderbilt Epidemiology Center (Nashville, Estats Units d'Amèrica)) ;
Silverman, Debra T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Soucek, Pavel (Laboratory of Pharmacogenomics, Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic) ;
Strobel, Oliver (Heidelberg University Hospital (Alemanya)) ;
Sund, Malin (Umeå University. Department of Surgical and Perioperative Sciences) ;
Małecka-Panas, Ewa (Medical University of Łodz (Polònia)) ;
Taylor, Philip R. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Tavano, Francesca (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Travis, Ruth C. (University of Oxford. Cancer Epidemiology Unit) ;
Thornquist, Mark (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ;
Tjønneland, Anne (Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark) ;
Tobias, Geoffrey S. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Trichopoulos, Dimitrios (Hellenic Health Foundation, Athens, Greece) ;
Vashist, Yogesh (University Hamburg-Eppendorf) ;
Vodicka, Pavel (Academy of Sciences of the Czech Republic) ;
Wactawski-Wende, Jean (University at Buffalo. Department of Social and Preventive Medicine) ;
Wentzensen, Nicolas (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Yu, Herbert (University of Hawaii Cancer Center) ;
Yu, Kai (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Zeleniuch-Jacquotte, Anne (New York University Cancer Institute) ;
Kooperberg, Charles (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ;
Risch, Harvey A. (Yale School of Public Health) ;
Jacobs, Eric J. (American Cancer Society (Atlanta, Estats Units d'Amèrica)) ;
Li, Donghui (University of Texas M.D. Anderson Cancer Center) ;
Fuchs, Charles (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Hoover, Robert (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Hartge, Patricia (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Chanock, Stephen (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Petersen, Gloria M. (Mayo Clinic (Rochester, Estats Units d'Amèrica)) ;
Stolzenberg-Solomon, Rachael S. (National Cancer Institute (Bethesda, Estats Units d'Amèrica)) ;
Wolpin, Brian M. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Department of Medical Oncology) ;
Kraft, Peter (Harvard School of Public Health (Boston, Estats Units d'Amèrica)) ;
Klein, Alison P. (Bloomberg School of Public Health. Department of Epidemiology) ;
Canzian, Federico (German Cancer Research Center (DKFZ)) ;
Amundadottir, Laufey T. (National Cancer Institute (Bethesda, Estats Units d'Amèrica))
Genome-wide association studies (GWAS) have identified common pancreatic cancer susceptibility variants at 13 chromosomal loci in individuals of European descent. To identify new susceptibility variants, we performed imputation based on 1000 Genomes (1000G) Project data and association analysis using 5,107 case and 8,845 control subjects from 27 cohort and case-control studies that participated in the PanScan I-III GWAS. [...]
2016 - 10.18632/oncotarget.11041
Oncotarget, Vol. 7 (august 2016) , p. 66328-66343
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