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8 p, 1.1 MB Consistent findings in glycaemic control, body weight and hypoglycaemia with iGlarLixi (insulin glargine/lixisenatide titratable fixed-ratio combination) vs insulin glargine across baseline HbA1c, BMI and diabetes duration categories in the LixiLan-L trial / Wysham, Carol (Rockwood Clinic (Spokane, Washington)) ; Bonadonna, Riccardo C (University of Parma) ; Aroda, Vanita R. (Medstar Health Research Institute (Hyattsville, Maryland)) ; Puig Domingo, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Kapitza, Christoph (Profil Institute (Neuss, Alemanya)) ; Stager, William (Sanofi) ; Yu, Christine (Sanofi) ; Niemoeller, Elisabeth (Sanofi) ; Souhami, Elisabeth (Sanofi) ; Bergenstal, Richard M. (International Diabetes Center (Minneapolis, Estats Units)) ; Universitat Autònoma de Barcelona
Aims: To assess the impact of baseline characteristics on clinical outcomes in the LixiLan-L trial, a randomized open-label trial designed to evaluate the efficacy and safety of iGlarLixi, a novel fixed-ratio combination of insulin glargine 100 U (iGlar) plus lixisenatide, in comparison with iGlar over 30 weeks in a population of patients with type 2 diabetes mellitus (T2DM) inadequately controlled on a previous regimen of basal insulin alone or in combination with 1 or 2 oral glucose-lowering drugs. [...]
2017 - 10.1111/dom.12961
Diabetes, Obesity and Metabolism, Vol. 19 (2017) , p. 1408-1415  

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