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Angiotensin receptor blockers and β-blockers in Marfan syndrome : an individual patient data meta-analysis of randomised trials / Pitcher, Alex (University of Oxford) ; Spata, Enti (University of Oxford) ; Emberson, Jonathan (University of Oxford) ; Davies, Kelly (University of Oxford) ; Halls, Heather (University of Oxford) ; Holland, Lisa (University of Oxford) ; Wilson, Kate (University of Oxford) ; Reith, Christina (University of Oxford) ; Child, Anne H (Imperial College London) ; Clayton, Tim (London School of Hygiene & Tropical Medicine) ; Dodd, Matthew (London School of Hygiene & Tropical Medicine) ; Flather, Marcus (University of East Anglia) ; Jin, Xu Yu (John Radcliffe Hospital (Oxford, Regne Unit)) ; Sandor, George (University of British Columbia) ; Groenink, Maarten (University of Amsterdam) ; Mulder, Barbara (University of Amsterdam) ; Backer, Julie De (Universitair Ziekenhuis Gent) ; Evangelista Masip, Arturo (Hospital Universitari Vall d'Hebron) ; Forteza, Alberto (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Teixido-Tura, Gisela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Boileau, Catherine (Université Paris Cité and Université Sorbonne Paris Nord) ; Jondeau, Guillaume (Université Paris Cité and Université Sorbonne Paris Nord) ; Milleron, Olivier (Université Paris Cité and Université Sorbonne Paris Nord) ; Lacro, Ronald V. (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ; Sleeper, Lynn A (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ; Chiu, Hsin-Hui (Taipei Tzu Chi Hospital) ; Wu, Mei-Hwan (National Taiwan University Hospital (Taipei, Taiwan)) ; Neubauer, Stefan (University of Oxford) ; Watkins, Hugh (University of Oxford) ; Dietz, Hal (Johns Hopkins University School of Medicine) ; Baigent, Colin (University of Oxford) ; Universitat Autònoma de Barcelona
Angiotensin Receptor Blockers (ARBs) and β-blockers are widely used in the treatment of Marfan syndrome to try to reduce the rate of progressive aortic root enlargement characteristic of this condition, but their separate and joint effects are uncertain. [...]
2022 - DOI (Digital Object Identifier)

10.1016/S0140-6736(22)01534-3
The Lancet (British), Vol. 400 (august 2022) , p. 822-831

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