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14 p, 1.6 MB A trigger enzyme in mycoplasma pneumoniae : impact of the glycerophosphodiesterase glpq on virulence and gene expression / Schmidl, Sebastian R. (Georg-August-University Göttingen. Department of General Microbiology) ; Otto, Andreas (Ernst-Moritz-Arndt-Universität Greifswald. Institut für Mikrobiologie und Molekularbiologie) ; Lluch Senar, Maria (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Piñol Ribas, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Busse, Julia (Georg-August-University Göttingen. Department of General Microbiology) ; Becher, Dörte (Ernst-Moritz-Arndt-Universität Greifswald. Institut für Mikrobiologie und Molekularbiologie) ; Stülke, Jörg (Georg-August-University Göttingen. Department of General Microbiology)
Mycoplasma pneumoniae is a causative agent of atypical pneumonia. The formation of hydrogen peroxide, a product of glycerol metabolism, is essential for host cell cytotoxicity. Phosphatidylcholine is the major carbon source available on lung epithelia, and its utilization requires the cleavage of deacylated phospholipids to glycerol-3-phosphate and choline. [...]
2011 - 10.1371/journal.ppat.1002263
PLoS pathogens, Vol. 7 issue 9 (2011) , art. e1002263  

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