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16 p, 2.0 MB Increased Skin Clearance and Quality of Life Improvement with Brodalumab Compared with Ustekinumab in Psoriasis Patients with Aggravating Lifestyle Factors / Kokolakis, Georgios (Charité-Universitätsmedizin Berlin. Clinic of Dermatology, Venereology and Allergology, Psoriasis Research and Treatment Centre) ; Vadstrup, Kasper (LEO Pharma A/S) ; Hansen, Jes Birger (LEO Pharma A/S) ; Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Obesity, smoking, and alcohol consumption are prevalent in psoriasis patients and have been associated with increased disease severity and reduced treatment adherence and response. This post hoc analysis of pooled data from the phase 3 AMAGINE-2 and -3 trials compared the efficacy of brodalumab versus ustekinumab in psoriasis patients with aggravating and potentially treatment-confounding lifestyle risk factors. [...]
2021 - 10.1007/s13555-021-00618-5
Dermatology and Therapy, Vol. 11 (october 2021) , p. 2027-2042  
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