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1.
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Gut microbial dysbiosis in patients with Cushing's disease in long-term remission. Relationship with cardiometabolic risk
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Valassi, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Manichanh, Chaysavanh (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Amodru, Vincent (Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER)) ;
Fernández, Pedro González (Cruces University Hospital, Bilbao) ;
Gaztambide, Sonia (Cruces University Hospital, Bilbao) ;
Yañez, Francisca (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martel-Duguech, Luciana (Hospital de la Santa Creu i Sant Pau) ;
Puig Domingo, Manuel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Webb, Susan M. (Universitat Autònoma de Barcelona. Departament de Medicina)
Patients with Cushing's disease (CD) in remission maintain an increased cardiovascular risk. Impaired characteristics of gut microbiome (dysbiosis) have been associated with several cardiometabolic risk factors. [...]
2023 -  10.3389/fendo.2023.1074757
Frontiers in Endocrinology, Vol. 14 (june 2023)
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2.
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Association between the Immunophenotype of Peripheral Blood from mCRPC Patients and the Outcomes of Radium-223 Treatment
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Cantó, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ;
Anguera, Georgia (Hospital de la Santa Creu i Sant Pau) ;
Jiménez, Natalia (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ;
Mellado, Begoña (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ;
Ramírez, Ona (Institut d'Investigació Biomèdica Sant Pau) ;
Mariscal, Anaís (Institut d'Investigació Biomèdica Sant Pau) ;
Maroto Rey, Pablo (Hospital de la Santa Creu i Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona. Departament de Medicina
(1) Background: Prostate cancer is the second most common cancer in men, with androgen suppression as the standard treatment. Despite initially responding to castration, most metastatic prostate cancer patients eventually experience progression. [...]
2023 - 10.3390/diagnostics13132222
Diagnostics, Vol. 13, Num. 13 (june 2023)
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3.
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Consensus recommendations for the treatment and management of patients with Fabry disease on migalastat : a modified Delphi study
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Bichet, Daniel G. (University of Montréal, Canada) ;
Hopkin, Robert J. (University of Cincinnati College of Medicine, United States) ;
Aguiar, Patrício (Lisbon University) ;
Allam, Sridhar R. (Texas Christian University, Fort Worth, United States) ;
Chien, Yin-Hsiu (National Taiwan University College of Medicine, Taipei, Taiwan) ;
Giugliani, Roberto (Postgraduate Program in Genetics and Molecular Biology (PPGBM) at Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil) ;
Kallish, Staci (University of Pennsylvania, Philadelphia, United States) ;
Kineen, Sabina (Patient Advocate, United States) ;
Lidove, Olivier (French Network of Inherited Metabolic Disorders (G2m), France) ;
Niu, Dau-Ming (National Yang Ming Chiao Tung University, Taipei, Taiwan) ;
Olivotto, Iacopo (Meyer University Children's Hospital, Florence, Italy) ;
Politei, Juan (Fundacion Para el Estudio de Enfermedades Neurometabolicas (FESEN), Buenos Aires, Argentina) ;
Rakoski, Paul (Patient Advocate, United States) ;
Torra Balcells, Roser (Institut d'Investigació Biomèdica Sant Pau) ;
Tøndel, Camilla (University of Bergen, Norway) ;
Hughes, Derralynn A. (Royal Free London NHS Foundation Trust and University College London, United Kingdom) ;
Universitat Autònoma de Barcelona. Departament de Medicina
Fabry disease is a progressive disorder caused by deficiency of the α-galactosidase A enzyme (α-Gal A), leading to multisystemic organ damage with heterogenous clinical presentation. The addition of the oral chaperone therapy migalastat to the available treatment options for Fabry disease is not yet universally reflected in all treatment guidelines. [...]
2023 - 10.3389/fmed.2023.1220637
Frontiers in Medicine, Vol. 10 (september 2023)
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4.
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Influence of body mass index on recurrence of atrial fibrillation after electrical cardioversion
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Ligero, Carmen (Hospital Universitari de Sant Joan, Universitat Rovira i Virgili) ;
Bazán, Víctor (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Guerra, José Maria (Hospital de la Santa Creu i Sant Pau) ;
Rodríguez-Mañero, Moisés (Hospital Clínico Universitario de Santiago, Santiago de Compostela) ;
Viñolas, Xavier (Hospital de la Santa Creu i Sant Pau) ;
Alegret i Colomé, Josep Maria (Hospital Universitari de Sant Joan, Universitat Rovira i Virgili) ;
Universitat Autònoma de Barcelona. Departament de Medicina
Several studies have shown an independent relationship between body mass index (BMI) and the incidence of atrial fibrillation (AF). However, little is known about the influence of BMI on AF recurrence after electrical cardioversion (ECV). [...]
2023 - 10.1371/journal.pone.0291938
PloS one, Vol. 18 (september 2023)
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5.
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Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy
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Ribeiro-Constante, Juliana (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Tristán-Noguero, A. (Institut de Recerca Sant Pau) ;
Martínez Calvo, Fernando Francisco (Hospital Universitario Miguel Servet) ;
Ibañez-Mico, Salvador (Hospital Universitario de Arrixaca) ;
Peña Segura, José Luis (Hospital Universitario Miguel Servet) ;
Ramos-Fernández, José Miguel (Hospital Regional Universitario de Málaga) ;
Moyano Chicano, María del Carmen (Hospital Regional Universitario de Málaga) ;
Camino León, Rafael (Hospital Universitario Reina Sofía) ;
Soto Insuga, Víctor (Hospital Universitario Infantil del Niño Jesús) ;
González Alguacil, Elena (Hospital Universitario Infantil del Niño Jesús) ;
Valera Dávila, Carlos (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Fernández-Jaén, Alberto (Hospital Universitario Quironsalud) ;
Plans, Laura (Xarxa Assistencial) ;
Camacho, Ana (Universidad Complutense de Madrid) ;
Visa-Reñé, Nuria (Hospital Universitario Arnau de Vilanova) ;
Martin-Tamayo Blázquez, María del Pilar (Hospital General Universitario de Jerez de la Frontera) ;
Paredes-Carmona, Fernando (Hospital Universitario Arnau de Vilanova) ;
Marti-Carrera, Itxaso (Hospital Universitario Donostia) ;
Hernández-Fabián, Aránzazu (Complejo Asistencial Universitario de Salamanca) ;
Tomas Davi, Meritxell (Xarxa Assistencial) ;
Sanchez, Merce Casadesus (Xarxa Assistencial) ;
Herraiz, Laura Cuesta (Hospital de Manises) ;
Pita, Patricia Fuentes (Hospital Clínico Universitario Santiago de Compostela) ;
Gonzalez, Teresa Bermejo (Servicio de Neurología Pediátrica) ;
O'Callaghan, Maria del Mar (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Iglesias Santa Polonia, Federico Felipe (Hospital Universitario de Burgos) ;
Cazorla, María Rosario (Hospital Universitario Puerta de Hierro Majadahonda) ;
Ferrando Lucas, María Teresa (Hospital Universitario Quironsalud) ;
González-Meneses, Antonio (Hospital Universitario Virgen del Rocío) ;
Sala-Coromina, Júlia (Hospital Universitari Vall d'Hebron) ;
Macaya Ruiz, Alfons (Hospital Universitari Vall d'Hebron) ;
Lasa-Aranzasti, Amaia (Hospital Universitari Vall d'Hebron) ;
Cueto-González, Anna Mª (Hospital Universitari Vall d'Hebron) ;
Valera Párraga, Francisca (Hospital Universitario de Arrixaca) ;
Campistol Plana, Jaume (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Serrano, Mercedes (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Alonso, Xenia (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Del Castillo-Berges, Diego (Institut de Recerca Sant Pau) ;
Schwartz-Palleja, Marc (Universitat Pompeu Fabra) ;
Illescas, Sofía (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Ramírez Camacho, Alia (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Sans Capdevila, Oscar (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
García-Cazorla, Angels (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Bayés, Àlex (Institut de Recerca Sant Pau) ;
Alonso-Colmenero, Itziar (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
SYNGAP1 haploinsufficiency results in a developmental and epileptic encephalopathy (DEE) causing generalized epilepsies accompanied by a spectrum of neurodevelopmental symptoms. Concerning interictal epileptiform discharges (IEDs) in electroencephalograms (EEG), potential biomarkers have been postulated, including changes in background activity, fixation-off sensitivity (FOS) or eye closure sensitivity (ECS). [...]
2024 - 10.3389/fcell.2024.1321282
Frontiers in Cell and Developmental Biology, Vol. 12 (march 2024)
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6.
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PCSK9 plasma concentration is associated with epicardial adipose tissue volume and metabolic control in patients with type 1 diabetes
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Sardà, Helena (Hospital de la Santa Creu I Sant Pau (Barcelona, Catalunya)) ;
Colom, Cristina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Benitez, Sonia (Institut de Recerca Sant Pau) ;
Carreras, Gemma (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Amigó, Judit (Hospital Universitari Vall d'Hebrón) ;
Miñambres, Inka (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Viladés Medel, David (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Blanco Vaca, Francisco (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sanchez-Quesada, Jose Luis (Institut de Recerca Sant Pau) ;
Pérez Pérez, Antonio (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Patients with type 1 diabetes (T1D) have a greater risk of cardiovascular disease. Proconvertase subtilisin-kexin 9 (PCSK9) is involved in the atherosclerosis process. This study aimed to determine the relationship between PCSK9 levels and epicardial adipose tissue (EAT) volume and cardiometabolic variables in patients with T1D. [...]
2024 - 10.1038/s41598-024-57708-5
Scientific reports, Vol. 14 (march 2024)
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7.
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Tofacitinib and Baricitinib in Type 2 Diabetic Patients with Rheumatoid Arthritis
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Martinez-Molina, Cristina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Díaz Torne, César (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Park, Hye S (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Feliu, Anna (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vidal, Silvia (Institut de Recerca Sant Pau) ;
Corominas, Hèctor (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Recently, a randomized controlled trial suggested a potential benefit of baricitinib in patients with diabetes mellitus, preserving β-cell function. However, the clinical evidence currently available is limited. [...]
2024 - 10.3390/medicina60030360
Medicina, Vol. 60 (february 2024)
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8.
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Urban environment and health : a cross-sectional multiregional project based on population health surveys in Spain (DAS-EP project) - study protocol
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Bereziartua, Ainhoa ;
Cabrera-León, Andrés ;
Subiza-Pérez, Mikel (Bradford Institute for Health Research) ;
Garcia-Baquero Moneo, Gonzalo (Universidad de Salamanca) ;
Delís Gomez, Salvador (Hospital Universitario Araba) ;
Ballester, Ferran (Universitat de València) ;
Estarlich, Marisa ;
Merelles, Antonio ;
Esplugues, Ana ;
Irles, Maria Angeles (General Directorate of Public Health) ;
Barona, Carmen (Universitat de València) ;
Mas, Rosa (Universitat de València) ;
Font-Ribera, Laia 1982- (Institut de Recerca Sant Pau) ;
Bartoll, Xavier (Institut de Recerca Sant Pau) ;
Pérez, Katherine (Institut de Recerca Sant Pau) ;
Oliveras, Laura (Institut de Recerca Sant Pau) ;
Binter, Anne-Claire (Universitat Pompeu Fabra) ;
Daponte, Antonio ;
García Mochon, Leticia (Instituto de Investigación Biosanitaria de Granada) ;
García Cortés, Helena ;
Sánchez-Cantalejo Garrido, María del Carmen ;
Lacasaña, Marina (Instituto de Investigación Biosanitaria de Granada) ;
Cáceres, Rocío (Universitat de Sevilla) ;
Rueda, María (Universitat de Granada) ;
Saez, Marc ;
Lertxundi, Aitana ;
Universitat Autònoma de Barcelona
The European Environment Agency estimates that 75% of the European population lives in cities. Despite the many advantages of city life, the risks and challenges to health arising from urbanisation need to be addressed in order to tackle the growing burden of disease and health inequalities in cities. [...]
2024 - 10.1136/bmjopen-2023-074252
BMJ open, Vol. 14 (march 2024)
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9.
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10.
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Small Non-Coding RNAs and Their Role in Locoregional Metastasis and Outcomes in Early-Stage Breast Cancer Patients
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Escuin i Borràs, Daniel (Institut de Recerca Sant Pau) ;
Bell, Olga (Institut de Recerca Sant Pau) ;
García-Valdecasas Vilanova, Bárbara (Institut de Recerca Sant Pau) ;
Clos Enríquez, Montserrat (Institut de Recerca Sant Pau) ;
Larrañaga, Itziar (Institut de Recerca Sant Pau) ;
López Vilaró, Laura (Institut de Recerca Sant Pau) ;
Mora, Josefina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Andrés, Marta (Institut de Recerca Sant Pau) ;
Arqueros, Cristina (Institut de Recerca Sant Pau) ;
Barnadas i Molins, Agustí (Institut de Recerca Sant Pau) ;
Universitat Autònoma de Barcelona
Deregulation of small non-coding RNAs (sncRNAs) has been associated with the onset of metastasis. We evaluated the expression of sncRNAs in patients with early-stage breast cancer, performing RNA sequencing in 60 patients for whom tumor and sentinel lymph node (SLN) samples were available, and conducting differential expression, gene ontology, enrichment and survival analyses. [...]
2024 - 10.3390/ijms25073982
International journal of molecular sciences, Vol. 25 (april 2024)
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