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11 p, 3.4 MB |
An interventional nationwide surveillance program lowers postoperative infection rates in elective colorectal surgery. A cohort study (2008-2019)
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Arroyo-Garcia, Nares (Universitat Internacional de Catalunya) ;
Badia, Josep M (Universitat Internacional de Catalunya) ;
Vázquez Fariñas, Ana (Universitat Autònoma de Barcelona) ;
Pera, Miguel (Hospital del Mar (Barcelona, Catalunya)) ;
Parés, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Limón, Enric (Universitat de Barcelona) ;
Almendral, Alexander (VINCat Program) ;
Piriz, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Pomar, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
López-Contreras, Joaquín (Institut d'Investigació Biomèdica Sant Pau) ;
Díez-García, C (Institut d'Investigació Biomèdica Sant Pau) ;
Fraccalvieri, Domenico (Hospital Universitari de Bellvitge) ;
Pujol, Miquel (Hospital Universitari de Bellvitge)
Colorectal surgery is associated with the highest rate of surgical site infection (SSI). This study analyses the effectiveness of an interventional surveillance program on SSI rates after elective colorectal surgery. [...]
2022 -  10.1016/j.ijsu.2022.106611
International journal of surgery, Vol. 102 (june 2022) , p. 106611
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2.
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9 p, 740.8 KB |
Incidence of Myelotoxicity and Other Adverse Effects Related to Thiopurine Starting in Patients with Inflammatory Bowel Disease : Retrospective Observational Study in a Third-Level Hospital
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Grau, Gerard (Centro Médico Teknon) ;
Brunet, Eduard (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Llovet, Laura Patricia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pedregal, Patricia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Villoria, Albert (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Melcarne, Luigi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Puy, Anna (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Garcia-Sague, Belen (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Frisancho, Luis Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ramírez-Lázaro, María José (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Lario, Sergio (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Calvet Calvo, Xavier (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
Background and objectives: Thiopurines are an effective treatment for the maintenance of remission in inflammatory bowel disease (IBD). They can present adverse effects (AEs), with myelotoxicity being the most relevant. [...]
2023 - 10.3390/jcm12206571
Journal of clinical medicine, Vol. 12 (october 2023)
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3.
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8 p, 634.0 KB |
COVAD survey 2 long-term outcomes : unmet need and protocol
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Fazal, Zoha Zahid (Aga Khan University Hospital) ;
Sen, Parikshit (Maulana Azad Medical College) ;
Joshi, Mrudula (Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals) ;
Ravichandran, Naveen (Sanjay Gandhi Postgraduate Institute of Medical Sciences. Department of Clinical Immunology and Rheumatology) ;
Lilleker, James B. (Manchester Centre for Clinical Neurosciences) ;
Agarwal, Vishwesh (Mahatma Gandhi Mission Medical College) ;
Kardes, Sinan (Istanbul University. Department of Medical Ecology and Hydroclimatology) ;
Kim, Minchul (University of Illinois College of Medicine Peoria. Department of Internal Medicine) ;
Day, Jessica (University of Melbourne. Department of Medical Biology) ;
Makol, Ashima (Mayo Clinic. Division of Rheumatology) ;
Milchert, Marcin (Pomeranian Medical University in Szczecin. Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology) ;
Gheita, Tamer (Cairo University. Rheumatology Department) ;
Salim, Babur (Rheumatology Department, Fauji Foundation Hospital (Pakistan)) ;
Velikova, Tsvetelina (Sofia University St. Kliment Ohridski. Department of Clinical Immunology) ;
Gracia-Ramos, Abraham Edgar (Department of Internal Medicine, General Hospital, National Medical Center, La Raza (Mèxic)) ;
Parodis, Ioannis (Örebro University. Department of Rheumatology) ;
Nikiphorou, Elena (King's College Hospital NHS Foundation Trust) ;
Tan, Ai Lyn (University of Leeds. Leeds Institute of Rheumatic and Musculoskeletal Medicine) ;
Chatterjee, Tulika (University of Illinois College of Medicine Peoria. Department of Internal Medicine, Center for Outcomes Research) ;
Cavagna, Lorenzo (Università degli studi di Pavia. Dipartimento di Medicine Interna e Terapia Medica) ;
Saavedra, Miguel A. (Centro Médico Nacional La Raza (Mèxic)) ;
Shinjo, Samuel Katsuyuki (Universidade de Sao Paulo) ;
Ziade, Nelly (Hotel-Dieu de France Hospital. Rheumatology Department) ;
Nune, Arvind (Southport and Ormskirk Hospital NHS Trust) ;
Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Knitza, Johannes (Universitätsklinikum Erlangen) ;
Kuwana, Masataka (Nippon Medical School Graduate School of Medicine. Department of Allergy and Rheumatology) ;
Gutiérrez, Carlos-Enrique Toro (Pontifica Javeriana University) ;
Caballero-Uribe, Carlo Vinicio (Department of Medicine, Hospital Universidad del Norte) ;
Dey, Dzifa (University of Ghana School of Medicine and Dentistry. Department of Medicine and Therapeutics) ;
Distler, Oliver (University of Zurich. Department of Rheumatology) ;
Chinoy, Hector (Salford Royal Hospital. Department of Rheumatology) ;
Agarwal, Vikas (Sanjay Gandhi Postgraduate Institute of Medical Sciences. Department of Clinical Immunology and Rheumatology) ;
Aggarwal, Rohit (University of Pittsburgh School of Medicine) ;
Gupta, Latika (City Hospital, Sandwell and West Birmingham Hospitals NHS Trust) ;
Universitat Autònoma de Barcelona
The online version contains supplementary material available at 10. 1007/s00296-022-05157-6.
2022 - 10.1007/s00296-022-05157-6
Rheumatology International, august 2022, p. 1-8
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8 p, 696.1 KB |
Clinical Patterns and Follow-Up of Inflammatory Arthritis and Other Immune-Related Adverse Events Induced by Checkpoint Inhibitors. A Multicenter Study
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Gómez-Puerta, José A. (Universitat de Barcelona. Departament de Medicina) ;
Lobo-Prat, David (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Pérez-García, Carolina (Hospital del Mar (Barcelona, Catalunya)) ;
Ponce, Andrés (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Frade-sosa, Beatriz (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Millán Arciniegas, Ana Milena (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Ojeda, Fabiola (Hospital del Mar (Barcelona, Catalunya)) ;
Ruiz-Esquide, Virginia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Corominas, Hèctor (Institut d'Investigació Biomèdica Sant Pau)
Objectives: To describe different clinical patterns of rheumatic immune-related adverse events (irAEs) induced by immune checkpoint inhibitors (ICI) and their rheumatic and oncologic outcomes. Methods: We classified clinical syndromes according to five different categories: non-inflammatory arthralgias (NIA), rheumatoid arthritis (RA)-like, psoriatic arthritis (PsA)-like, polymyalgia rheumatica (PMR)-like, and a miscellaneous group of patients with other syndromes. [...]
2022 - 10.3389/fmed.2022.888377
Frontiers in Medicine, Vol. 9 (June 2022) , p. 888377
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10 p, 7.6 MB |
Cell Senescence-Related Pathways Are Enriched in Breast Cancer Patients With Late Toxicity After Radiotherapy and Low Radiation-Induced Lymphocyte Apoptosis
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Aguado-Flor, Ester (Vall d'Hebron Institut d'Oncologia) ;
Fuentes-Raspall, María J. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Gonzalo, Ricardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alonso, Carmen (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Ramon y Cajal, Teresa (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Fisas, David (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Seoane, A. (Hospital Universitari Vall d'Hebron) ;
Sánchez, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Giralt López de Sagredo, Jordi (Vall d'Hebron Institut d'Oncologia) ;
Diez, Orland (Hospital Universitari Vall d'Hebron) ;
Gutiérrez-Enríquez, Sara (Vall d'Hebron Institut d'Oncologia) ;
Universitat Autònoma de Barcelona
Background: Radiation-induced late effects are a common cause of morbidity among cancer survivors. The biomarker with the best evidence as a predictive test of late reactions is the radiation-induced lymphocyte apoptosis (RILA) assay. [...]
2022 - 10.3389/fonc.2022.825703
Frontiers in Oncology, Vol. 12 (24 2022) , p. 825703
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15 p, 354.3 KB |
Adverse events associated with the use of recommended vaccines during pregnancy : An overview of systematic reviews
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Macias Saint-Gerons, Diego (Department of Health Systems and Services (HSS)/Unit of Medicines and Health Technologies (MT). Pan American Health Organization PAHO/WHO) ;
Solà, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
De Mucio, Bremen (Department of Preventive Medicine. School of Medicine. University of the Republic. Montevideo) ;
Arevalo-Rodriguez, Ingrid (Hospital Universitario Ramón y Cajal (Madrid)) ;
Alemán, Alicia (Department of Preventive Medicine. School of Medicine. University of the Republic. Montevideo) ;
Castro, José Luis (Department of Health Systems and Services (HSS)/Unit of Medicines and Health Technologies (MT). Pan American Health Organization PAHO/WHO) ;
Ropero Álvarez, Alba María (Department of Family. Gender and Life Course. Immunization Unit. Pan American Health Organization PAHO/WHO)
Introduction: Maternal immunization is aimed at reducing morbidity and mortality in pregnant women and their newborns. Updated evidence synthesis of maternal-fetal outcomes is constantly needed to ensure that the risk-benefit of vaccination during pregnancy remains positive. [...]
2021 - 10.1016/j.vaccine.2020.07.048
Vaccine, Vol. 39 (july 2021) , p. B12-B26
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4 p, 461.1 KB |
Risk factors for nosocomial bloodstream infections in COVID-19 affected patients : protocol for a case-control study
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Codina-Jiménez, Carla (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Marin, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Álvarez, Marlene (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quesada, Maria Dolores (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Rodríguez-Ponga, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Valls, Ester (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Quiñones, Carles (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Nosocomial bloodstream infection (nBSI) is an important clinical concern among COVID-19 hospitalised patients. It can cause sepsis and septic shock leading to high morbidity, mortality, and the emergence of antibiotic resistance. [...]
2021 - 10.1136/ejhpharm-2021-002776
European Journal of Hospital Pharmacy, Vol. 29 (august 2021) , p. e2-e5
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16 p, 967.2 KB |
Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs
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Fuggle, N. R. (University of Southampton) ;
Cooper, Cyrus (University of Oxford) ;
Harvey, N. C. (University of Southampton) ;
Al-Daghri, Nasser (King Saud University) ;
Brandi, Maria Luisa (University Hospital of Florence) ;
Bruyère, Olivier (WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium) ;
Cano Sánchez, Antonio (University of Valencia) ;
Dennison, E. M. (University of Southampton) ;
Díez Pérez, Adolfo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kaufman, J.-M. (Universitair Ziekenhuis Gent) ;
Palacios, S. (The Palacios Institute of Women's Health, Madrid) ;
Prieto-Alhambra, D. (University of Oxford) ;
Rozenberg, S. (CHU St Pierre, Bruxelles) ;
Thomas, T. (CHU de Saint-Etienne, France) ;
Tremollieres, F. (Toulouse University Hospital) ;
Rizzoli, R. (Hôpitaux Universitaires Genève) ;
Kanis, John A (Australian Catholic University) ;
Reginster, Jean-Yves (King Saud University) ;
Universitat Autònoma de Barcelona
The incidence of osteoporosis and cardiovascular disease increases with age, and there are potentially shared mechanistic associations between the two conditions. It is therefore highly relevant to understand the cardiovascular implications of osteoporosis medications. [...]
2020 - 10.1007/s40265-020-01364-2
Drugs, Vol. 80 (july 2020) , p. 1537-1552
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7 p, 969.7 KB |
Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly : A Population-Based Cohort Study in an Electronic Prescription Database
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Ortiz de Landaluce, Leticia (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ;
Carbonell, Pere (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ;
Asensio Ostos, Carmen (Fundació Institut Català de Farmacologia) ;
Escoda, Núria (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ;
López, Pilar (Servei Català de la Salut. Gerència de Prestacions Farmacèutiques i Accés al Medicament) ;
Laporte Rosselló, Joan-Ramón (Fundació Institut Català de Farmacologia) ;
Universitat Autònoma de Barcelona
Gabapentin and pregabalin are widely prescribed to elderly people, but data on their pharmacokinetics, safety, and efficacy in this population are scarce. Neurological adverse effects are common. Atrial fibrillation (AF) associated with their use has been described in several case reports and case series, but the incidence is unknown. [...]
2018 - 10.1007/s40264-018-0695-6
Drug Safety, Vol. 41 (june 2018) , p. 1325-1331
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