Results overview: Found 5 records in 0.02 seconds.
Articles, 5 records found
Articles 5 records found  
1.
12 p, 1.4 MB Evaluation of the immunological profile of antibody-functionalized metal-filled single-walled carbon nanocapsules for targeted radiotherapy / Perez Ruiz De Garibay, Aritz (Université de Strasbourg. Centre national de la recherche scientifique) ; Spinato, Cinzia (Université de Strasbourg. Centre national de la recherche scientifique) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Bourgognon, Maxime (King's College London. Institute of Pharmaceutical Science) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Ménard Moyon, Cécilia (Université de Strasbourg. Centre national de la recherche scientifique) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona) ; Bianco, Alberto (Université de Strasbourg. Centre national de la recherche scientifique)
This study investigates the immune responses induced by metal-filled single-walled carbon nanotubes (SWCNT) under in vitro, ex vivo and in vivo settings. Either empty amino-functionalized CNTs [SWCNT-NH 2 (1)] or samarium chloride-filled amino-functionalized CNTs with [SmCl 3 @SWCNT-mAb (3)] or without [SmCl 3 @SWCNT-NH 2 (2)] Cetuximab functionalization were tested. [...]
2017 - 10.1038/srep42605
Scientific Reports, Vol. 7 (February 2017) , art. 42605  
2.
19 p, 868.7 KB Design of antibody-functionalized carbon nanotubes filled with radioactivable metals towards a targeted anticancer therapy / Spinato, Cinzia (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Perez Ruiz De Garibay, Aritz (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Kierkowicz, Magdalena (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Bourgognon, Maxime (King's College London. Institute of Pharmaceutical Science) ; Wang, Julie Tzu-Wen (King's College London. Institute of Pharmaceutical Science) ; Ménard-Moyon, Cécilia (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science) ; Ballesteros Pérez, Belén (Institut Català de Nanociència i Nanotecnologia) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona) ; Bianco, Alberto (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique)
In the present work we have devised the synthesis of a novel promising carbon nanotube carrier for the targeted delivery of radioactivity, through a combination of endohedral and exohedral functionalization. [...]
2016 - 10.1039/c5nr07923c
Nanoscale, Vol. 8, issue 25 (2016) , p. 12626-12638  
3.
8 p, 2.5 MB Protein-Corona-by-Design in 2D : A Reliable Platform to Decode Bio–Nano Interactions for the Next-Generation Quality-by-Design Nanomedicines / Mei, Kuo‐Ching (King's College London) ; Ghazaryan, Artur (Max Planck Institute for Polymer Research) ; Teoh, Er Zhen (King's College London) ; Summers, Huw D. (Swansea University) ; Li, Yueting (Guizhou Medical University) ; Ballesteros Pérez, Belén (Institut Català de Nanociència i Nanotecnologia) ; Piasecka, Justyna (Swansea University) ; Walters, Adam (King's College London) ; Hider, Robert C. (King's College London) ; Mailänder, Volker (Johannes Gutenberg-University. Department of Dermatology) ; Al-Jamal, Khuloud T. (King's College London)
Hard corona (HC) protein, i. e. , the environmental proteins of the biological medium that are bound to a nanosurface, is known to affect the biological fate of a nanomedicine. Due to the size, curvature, and specific surface area (SSA) 3-factor interactions inherited in the traditional 3D nanoparticle, HC-dependent bio–nano interactions are often poorly probed and interpreted. [...]
2018 - 10.1002/adma.201802732
Advanced materials, Vol. 30, Issue 40 (October 2018) , art. 1802732  
4.
16 p, 2.1 MB Cationic liposome- multi-walled carbon nanotubes hybrids for dual siPLK1 and doxorubicin delivery in vitro / Pereira, Sara (University of East Anglia. School of Pharmacy) ; Lee, Jin (King's College London. Institute of Pharmaceutical Science) ; Rubio, Noelia (King's College London. Institute of Pharmaceutical Science) ; Hassan, Hatem A. F. M. (King's College London. Institute of Pharmaceutical Science) ; Suffian, Izzat Bin Mohamed (King's College London. Institute of Pharmaceutical Science) ; Wang, Julie T. W. (King's College London. Institute of Pharmaceutical Science) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Ballesteros Pérez, Belén (Institut Català de Nanociència i Nanotecnologia) ; Al-Jamal, Wafa' T. (University of East Anglia. School of Pharmacy) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science)
To formulate f -MWNTs-cationic liposome hybrids for the simultaneous delivery of siPLK1 and doxorubicin to cancer cells. f -MWNTs-cationic liposome hybrids were prepared by the thin film hydration method where the lipid film was hydrated with 100 μg/ml or 1 mg/ml of ox-MWNTs-NH₃+ or MWNTs-NH₃+ in 5% dextrose. [...]
2015 - 10.1007/s11095-015-1707-1
Pharmaceutical research, Vol. 32, Issue 10 (Oct. 2015) , p. 3293-3308  
5.
16 p, 4.7 MB The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo / Kafa, Houmam (King's College London. Institute of Pharmaceutical Science) ; Wang, Julie Tzu-Wen (King's College London. Institute of Pharmaceutical Science) ; Rubio, Noelia (King's College London. Institute of Pharmaceutical Science) ; Venner, Kerrie (University College London. Institute of Neurology) ; Anderson, Glenn (Great Ormond Street Hospital for Children. Histopathology Department) ; Pach, Elzbieta (Institut Catala de Nanociència i Nanotecnologia) ; Ballesteros Pérez, Belén (Institut Català de Nanociència i Nanotecnologia) ; Preston, Jane E. (King's College London. Institute of Pharmaceutical Science) ; Abbott, N. Joan (King's College London. Institute of Pharmaceutical Science) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science)
Carbon nanotubes (CNTs) are a novel nanocarriers with interesting physical and chemical properties. Here we investigate the ability of amino-functionalized multi-walled carbon nanotubes (MWNTs-NH₃+) to cross the Blood-Brain Barrier (BBB) in vitro using a co-culture BBB model comprising primary porcine brain endothelial cells (PBEC) and primary rat astrocytes, and in vivo following a systemic administration of radiolabelled f -MWNTs. [...]
2015 - 10.1016/j.biomaterials.2015.02.083
Biomaterials, Vol. 53 (June 2015) , p. 437-452  

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