Home > Search Results: Alfonso, Carlos
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Results overview: Found 5 records in 0.02 seconds.
Articles, 5 records found
Articles 5 records found  
1.
14 p, 2.5 MB Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation / Esperante, Sebastián A. (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Varejão, Nathalia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Pinheiro, Francisca (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Sant'Anna, Ricardo (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Sora, Valentina (Technical University of Denmark. Cancer Systems Biology, Health and Technology Department) ; Papaleo, Elena (Technical University of Denmark. Cancer Systems Biology, Health and Technology Department) ; Rivas, Germán (Centro de Investigaciones Biológicas (Madrid)) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Hereditary transthyretin amyloidosis (ATTR) is an autosomal dominant disease characterized by the extracellular deposition of the transport protein transthyretin (TTR) as amyloid fibrils. Despite the progress achieved in recent years, understanding why different TTR residue substitutions lead to different clinical manifestations remains elusive. [...]
2021 - 10.1016/j.jbc.2021.101039
Journal of biological chemistry, Vol. 297, Issue 3 (September 2021) , art. 101039  
Detailed record - Creative Commons
2.
14 p, 1.5 MB Multiple Layered Control of the Conjugation Process of the Bacillus subtilis Plasmid pLS20 / Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa) ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ; Ares, Saúl (Centro Nacional de Biotecnología. Departamento de Biología de Sistemas) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Rojo, Fernando (Centro Nacional de Biotecnología. Department of Microbial Biotechnology) ; Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ; Wu, Ling Juan (Newcastle University. Centre for Bacterial Cell Biology, Biosciences Institute)
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of antibiotic resistance, virulence and toxin genes. During conjugation, DNA is transferred from a donor to a recipient cell via a sophisticated channel connecting the two cells. [...]
2021 - 10.3389/fmolb.2021.648468
Frontiers in Molecular Biosciences, Vol. 8 (March 2021) , art. 648468  
Detailed record - Creative Commons
3.
15 p, 7.0 MB Inactivation of the dimeric Rap anti-repressor of the conjugation operon is mediated by peptide-induced tetramerization / Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Bernardo, Nerea (ALBA Laboratori de Llum de Sincrotró) ; Miguel-Arribas, Andrés (Centro de Biología Molecular Severo Ochoa) ; Singh, Praveen K. (Centro de Biología Molecular Severo Ochoa) ; Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Malfois, Marc (ALBA Laboratori de Llum de Sincrotró) ; Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa) ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró)
Quorum sensing allows bacterial cells to communicate through the release of soluble signaling molecules into the surrounding medium. It plays a pivotal role in controlling bacterial conjugation in Gram-positive cells, a process that has tremendous impact on health. [...]
2020 - 10.1093/nar/gkaa540
Nucleic acids research, Vol. 48, issue 14 (Aug. 2020) , p. 8113-8127  
Detailed record - Creative Commons
4.
17 p, 5.8 MB Novel regulatory mechanism of establishment genes of conjugative plasmids / Val-Calvo, Jorge (Centro de Biología Molecular Severo Ochoa) ; Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ; Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Miguel Arribas, Andrés (Centro de Biología Molecular Severo Ochoa) ; Abia, David (Centro de Biología Molecular Severo Ochoa) ; Sánchez-Hevia, Dione L. (Centro de Biología Molecular Severo Ochoa) ; Serrano, Ester (Centro de Biología Molecular Severo Ochoa) ; Gago-Córdoba, César (Centro de Biología Molecular Severo Ochoa) ; Ares, Saúl (Universidad Carlos III de Madrid) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Rojo, Fernando (Centro Nacional de Biotecnología (CSIC)) ; Wu, Ling J. (Newcastle University) ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ; Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa)
The principal route for dissemination of antibiotic resistance genes is conjugation by which a conjugative DNA element is transferred from a donor to a recipient cell. Conjugative elements contain genes that are important for their establishment in the new host, for instance by counteracting the host defense mechanisms acting against incoming foreign DNA. [...]
2018 - 10.1093/nar/gky996
Nucleic acids research, Vol. 46, Issue 22 (December 2018) , p. 11910-11926  
Detailed record - Creative Commons
5.
23 p, 2.2 MB Discovery of a new family of relaxases in Firmicutes bacteria / Gayetri Ramachandran, Andrés (Centro de Biología Molecular Severo Ochoa) ; Miguel Arribas, Andrés (Centro de Biología Molecular Severo Ochoa) ; Abia, David (Centro de Biología Molecular Severo Ochoa) ; Singh, Praveen K. (Centro de Biología Molecular Severo Ochoa) ; Crespo, Isidro (ALBA Laboratori de Llum de Sincrotró) ; Gago-Córdoba, César (Centro de Biología Molecular Severo Ochoa) ; Hao, Jian An (Centro de Biología Molecular Severo Ochoa) ; Luque-Ortega, Juan Román (Centro de Investigaciones Biológicas (Madrid)) ; Alfonso, Carlos (Centro de Investigaciones Biológicas (Madrid)) ; Wu, Ling J. (Newcastle University. Institute for Cell and Molecular Biosciences. Centre for Bacterial Cell Biology) ; Boer, Roeland (ALBA Laboratori de Llum de Sincrotró) ; Meijer, Wilfried J. J. (Centro de Biología Molecular Severo Ochoa)
Antibiotic resistance is a serious global problem. Antibiotic resistance genes (ARG), which are widespread in environmental bacteria, can be transferred to pathogenic bacteria via horizontal gene transfer (HGT). [...]
2017 - 10.1371/journal.pgen.1006586
PLoS Genetics, Vol. 13, issue 2 (Feb. 2017) , e1006586  
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See also: similar author names
1 Alfonso, C.
3 Alfonso, Carla
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