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15 p, 3.8 MB Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease / Barranco, Neus (Universitat de Barcelona. Institut de Neurociències) ; Plá, Virginia (University of Rochester Medical Center) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez-Domínguez, Irene (Universitat de Barcelona) ; Fischer-Colbrie, Reiner (Innsbruck Medical University) ; Ferrer, Isidro (Institut d'Investigació Biomèdica de Bellvitge) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Aguado, Fernando (Universitat de Barcelona) ; Universitat Autònoma de Barcelona
New fluid biomarkers for Alzheimer's disease (AD) that reveal synaptic and neural network dysfunctions are needed for clinical practice and therapeutic trial design. Dense core vesicle (DCV) cargos are promising cerebrospinal fluid (CSF) indicators of synaptic failure in AD patients. [...]
2021 - 10.1186/s40035-021-00263-0
Translational Neurodegeneration, Vol. 10 (september 2021)  

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