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11 p, 771.0 KB |
Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?
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Cabrera Serrano, Antonio José (Instituto de Investigación Sanitaria de Granada) ;
Sánchez Maldonado, José Manuel (Instituto de Investigación Sanitaria de Granada) ;
ter Horst, Rob (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) ;
Macauda, Angelica (German Cancer Research Center) ;
García Martín, Paloma (Hospital Campus de la Salud (Granada)) ;
Benavente, Yolanda (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Landi, Stefano (Department of Biology. University of Pisa) ;
Clay-Gilmour, Alyssa (Department of Epidemiology & Biostatistics. Arnold School of Public Health. University of South Carolina) ;
Niazi, Yasmeen (Hopp Children's Cancer Center) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez-Sevilla, Juan Jose (Department of Leukemia. The University of Texas MD Anderson Cancer Center) ;
Pérez, Eva María (Hospital Campus de la Salud) ;
Maffei, Rossana (University of Modena and Reggio Emilia) ;
Blanco, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giaccherini, Matteo (Department of Biology. University of Pisa) ;
Cerhan, James R. (Department of Quantitative Health Sciences. Mayo Clinic) ;
Marasca, Roberto (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia. AOU Policlinico) ;
Lopez Nevot, Miguel Angel (Hospital Universitario Virgen de las Nieves (Granada)) ;
Chen-Liang, Tzu Hua (Hospital Universitario Morales Meseguer (Múrcia)) ;
Thomsen, Hauke (MSB Medical School Berlin) ;
Gámez, Irene (Hematology Department. Morales Meseguer University Hospital) ;
Campa, Daniele (Department of Biology. University of Pisa) ;
Moreno Aguado, Víctor (Facultat de Medicina. Universitat de Barcelona) ;
de Sanjosé, Silvia (Universitat de Barcelona) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Álvarez, María Flor (Instituto de Investigación Biomédica de Salamanca) ;
Dierssen-Sotos, Trinidad (Universidad de Cantabria) ;
Jerez, Andrés (Vall d'Hebron Institut d'Oncologia) ;
Butrym, Aleksandra (Department of Cancer Prevention and Therapy. Medical University of Wrocław) ;
Norman, Aaron D. (Department of Quantitative Health Sciences. Mayo Clinic) ;
Luppi, Mario (University of Modena and Reggio Emilia) ;
Slager, Susan L. (Mayo Clinic) ;
Hemminki, Kari (Charles University in Prague) ;
Li, Yang (Hannover Medical School) ;
Berndt, Sonja I. (National Institutes of Health (Estats Units d'Amèrica)) ;
Casabonne, Delphine (Universitat de Barcelona) ;
Alcoceba, Miguel (Instituto de Investigación Biomédica de Salamanca) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Netea, Mihai G. (Department for Immunology & Metabolism. University of Bonn) ;
Försti, Asta (Hopp Children's Cancer Center) ;
Canzian, Federico (German Cancer Research Center) ;
Sainz, Juan (Department of Biochemistry and Molecular Biology. Universidad de Granada)
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults worldwide. Although genome-wide association studies (GWAS) have uncovered the germline genetic component underlying CLL susceptibility, the potential use of GWAS-identified risk variants to predict disease progression and patient survival remains unexplored. [...]
2023 -  10.3390/ijms24098005
International journal of molecular sciences, Vol. 24 Núm. 9 (may 2023) , p. 8005
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6 p, 1.5 MB |
Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia : a CRuCIAL study
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García Martín, Paloma (Hospital Campus de la Salud (Granada)) ;
Moñiz Díez, Ana (Instituto de Investigación Sanitaria de Granada) ;
Sánchez Maldonado, José Manuel (Instituto de Investigación Sanitaria de Granada) ;
Cabrera Serrano, Antonio José (Instituto de Investigación Sanitaria de Granada) ;
ter Horst, Rob (CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences) ;
Benavente, Yolanda (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Landi, Stefano (Department of Biology. University of Pisa) ;
Macauda, Angelica (German Cancer Research Center) ;
Clay-Gilmour, Alyssa (University of South Carolina) ;
Hernández-Mohedo, Francisca (Instituto de Investigación Sanitaria de Granada) ;
Niazi, Yasmeen (Hopp Children's Cancer Center) ;
González-Sierra, Pedro Antonio (Instituto de Investigación Sanitaria de Granada) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez-Sevilla, Juan Jose (Hospital del Mar (Barcelona, Catalunya)) ;
Maffei, Rossana (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia) ;
Blanco, Gonzalo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giaccherini, Matteo (Department of Biology. University of Pisa) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cerhan, James (Mayo Clinic) ;
Marasca, Roberto (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia) ;
Cañadas-Garre, Marisa (Instituto de Investigación Sanitaria de Granada) ;
Lopez Nevot, Miguel Angel (Hospital Universitario Virgen de las Nieves (Granada)) ;
Chen-Liang, Tzu (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Thomsen, Hauke (ProtaGene CGT GmbH (Alemanya)) ;
Gámez, Irene (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Morros, Rosa (Institut d'Investigació Biomèdica de Bellvitge) ;
Marcos-Gragera, Rafael (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Álvarez, María (Hospital Universitario de Salamanca) ;
Llorca, Javier (Universidad de Cantabria) ;
Jerez, Andrés (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Berndt, Sonja (National Institutes of Health (Estats Units d'Amèrica)) ;
Butrym, Aleksandra (Medical University of Wrocław) ;
Norman, Aaron D. (Mayo Clinic) ;
Casabonne, Delphine (CCIBER Epidemiología y Salud Pública (Madrid)) ;
Luppi, Mario (Department of Medical and Surgical Sciences. University of Modena and Reggio Emilia) ;
Slager, Susan L. (Mayo Clinic) ;
Hemminki, Kari (Charles University in Prague) ;
Li, Yang (CHannover Medical School) ;
Alcoceba, Miguel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Campa, Daniele (Department of Biology. University of Pisa) ;
Canzian, Federico (German Cancer Research Center (Alemanya)) ;
De Sanjose, Silvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Försti, Asta (Hopp Children's Cancer Center) ;
Netea, Mihai G. (University of Bonn) ;
Jurado, Manuel (Instituto de Investigación Sanitaria de Granada) ;
Sainz, Juan (Universidad de Granada. Departamento de Bioquímica y Biología Molecular) ;
Universitat Autònoma de Barcelona
2022 - 10.1038/s41408-022-00676-8
Blood Cancer Journal, Vol. 12 Núm. 5 (may 2022) , p. 79
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10 p, 1.6 MB |
SNPs in bone-related miRNAs are associated with the osteoporotic phenotype
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De-Ugarte, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Caro-Molina, Enrique (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodríguez-Sanz, Maria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
García-Pérez, Miguel Angel (Universitat de València) ;
Olmos, José M. (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Sosa-Henríquez, Manuel (Universidad de Las Palmas de Gran Canaria) ;
Pérez-Cano, Ramón (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Gómez-Alonso, Carlos (Hospital Universitario Central de Asturias) ;
Del Rio, Luis (vCETIR Grup Mèdic (Barcelona , Catalunya)) ;
Mateo-Agudo, Jesús (Hospital Universitario Miguel Servet (Saragossa)) ;
Blázquez-Cabrera, José Antonio (Complejo Hospitalario Universitario de Albacete) ;
González-Macías, Jesús (Universidad de Cantabria) ;
Pino-Montes, Javier del (Instituto de Investigación Biomédica de Salamanca) ;
Muñoz-Torres, Manuel (Hospital Universitario San Cecilio (Granada)) ;
Diaz-Curiel, Manuel (Hospital Universitario Fundación Jiménez Díaz) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Cano, Antonio (Universitat de València) ;
Pérez-Castrillon, José Luis (Hospital Universitario Río Hortega (Valladolid)) ;
Nogués Solán, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Garcia-Giralt, Natalia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Díez Pérez, Adolfo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Biogenesis and function of microRNAs can be influenced by genetic variants in the pri-miRNA sequences leading to phenotypic variability. This study aims to identify single nucleotide polymorphisms (SNPs) affecting the expression levels of bone-related mature microRNAs and thus, triggering an osteoporotic phenotype. [...]
2017 - 10.1038/s41598-017-00641-7
Scientific reports, Vol. 7 (march 2017)
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13 p, 1.3 MB |
Comparative analysis of rosaceous genomes and the reconstruction of a putative ancestral genome for the family
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Illa, Eudald (Centre de Recerca en Agrigenòmica) ;
Sargent, Daniel J. (East Malling Research) ;
López Girona, Elena (East Malling Research) ;
Bushakra, Jill (The New Zealand Institute for Plant & Food Research Ltd) ;
Cestaro, Alessandro (Fondazione Edmund Mach. Istituto agrario di San Michele all'Adige) ;
Crowhurst, Ross (The New Zealand Institute for Plant & Food Research Ltd) ;
Pindo, Massimo (Fondazione Edmund Mach. Istituto agrario di San Michele all'Adige) ;
Cabrera, Antonio (The Ohio State University. Department of Horticulture and Crop Science) ;
Van der Knaap, Esther (The Ohio State University. Department of Horticulture and Crop Science) ;
Iezzoni, Amy (Michigan State University. Department of Horticulture) ;
Gardiner, Susan (The New Zealand Institute for Plant & Food Research Ltd) ;
Velasco, Riccardo (Fondazione Edmund Mach. Istituto agrario di San Michele all'Adige) ;
Arús i Gorina, Pere (Centre de Recerca en Agrigenòmica) ;
Chagné, David (The New Zealand Institute for Plant & Food Research Ltd) ;
Troggio, Michela (Fondazione Edmund Mach. Istituto agrario di San Michele all'Adige)
Background. comparative genome mapping studies in Rosaceae have been conducted until now by aligning genetic maps within the same genus, or closely related genera and using a limited number of common markers. [...]
2011 - 10.1186/1471-2148-11-9
BMC evolutionary biology, Vol. 11 (January 2011) , art. 9
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