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19 p, 2.4 MB |
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
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Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sitlani, Collen M. (University of Washington) ;
Bone, William P. (University of Pennsylvania) ;
Martín Bórnez, Miguel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Voight, Benjamin F. (University of Pennsylvania Perelman School of Medicine) ;
Morrison, Alanna C. ;
Damrauer, Scott M. ;
de Vries, Paul S. ;
Smith, Nicholas L. ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Dehghan, Abbas ;
Heath, Adam S. ;
Reiner, Alex P. ;
Johnson, Andrew ;
Richmond, Anne ;
Peters, Annette ;
van Hylckama Vlieg, Astrid ;
McKnight, Barbara ;
Psaty, Bruce M. ;
Hayward, Caroline ;
Ward-Caviness, Cavin ;
O'Donnell, Cristopher ;
Chasman, Daniel ;
Strachan, David P. ;
Tregouet, David A. ;
Mook-Kanamori, Dennis ;
Gill, Dipender ;
Thibord, Florian ;
Asselbergs, Folkert W. ;
Leebeek, Frank W. G. ;
Rosendaal, Frits R. ;
Davies, Gail ;
Homuth, Georg ;
Temprano, Gerard ;
Campbell, Harry ;
Taylor, Herman A. ;
Bressler, Jan ;
Huffman, Jennifer E. ;
Rotter, Jerome I. ;
Yao, Jie ;
Wilson, James F. ;
Bis, Joshua C. ;
Hahn, Julie M. ;
Desch, Karl C. ;
Wiggins, Kerri L. ;
Raffield, Laura M. ;
Bielak, Lawrence F. ;
Yanek, Lisa R. ;
Kleber, Marcus E. ;
Mueller, Martina ;
Kavousi, Maryam ;
Mangino, Massimo ;
Liu, Melissa ;
Brown, Michael R. ;
Conomos, Matthew P. ;
Jhun, Min-A. ;
Chen, Ming-Huei ;
de Maat, Moniek P. M. ;
Pankratz, Nathan ;
Smith, Nicholas L. ;
Peyser, Patricia A. ;
Elliot, Paul ;
Wei, Peng ;
Wild, Philipp S. ;
Morange, Pierre E. ;
van der Harst, Pim ;
Yang, Qiong ;
Le, Ngoc-Quynh ;
Marioni, Riccardo ;
Li, Ruifang ;
Damrauer, Scott M. ;
Cox, Simon R. ;
Trompet, Stella ;
Felix, Stephan B. ;
Völker, Uwe ;
Tang, Weihong ;
Koenig, Wolfgang ;
Jukema, J. Wouter ;
Guo, Xiuqing ;
Lindstrom, Sara ;
Wang, Lu ;
Smith, Erin N. ;
Gordon, William ;
van Hylckama Vlieg, Astrid ;
de Andrade, Mariza ;
Brody, Jennifer A. ;
Pattee, Jack W. ;
Haessler, Jeffrey ;
Brumpton, Ben M. ;
Suchon, Pierre ;
Chen, Ming-Huei ;
Turman, Constance ;
Germain, Marine ;
Wiggins, Kerri L. ;
MacDonald, James ;
Braekkan, Sigrid K. ;
Armasu, Sebastian M. ;
Pankratz, Nathan ;
Jackson, Rabecca D. ;
Nielsen, Jonas B. ;
Giulianini, Franco ;
Puurunen, Marja K. ;
Ibrahim, Manal ;
Heckbert, Susan R. ;
Bammler, Theo K. ;
Frazer, Kelly A. ;
McCauley, Bryan M. ;
Taylor, Kent ;
Pankow, James S. ;
Reiner, Alexander P. ;
Gabrielsen, Maiken E. ;
Deleuze, Jean-François ;
O'Donnell, Chris J. ;
Kim, Jihye ;
McKnight, Barbara ;
Kraft, Peter ;
Hansen, John-Bjarne ;
Rosendaal, Frits R. ;
Heit, John A. ;
Psaty, Bruce M. ;
Tang, Weihong ;
Kooperberg, Charles ;
Hveem, Kristian ;
Ridker, Paul M. ;
Morange, Pierre-Emmanuel ;
Johnson, Andrew D. ;
Kabrhel, Christopher ;
Trégouët, David-Alexandre ;
Smith, Nicholas L. ;
Malik, Rainer ;
Chauhan, Ganesh ;
Traylor, Matthew ;
Sargurupremraj, Muralidharan ;
Okada, Yukinori ;
Mishra, Aniket ;
Rutten-Jacobs, Loes ;
Giese, Anne-Katrin ;
van der Laan, Sander W. ;
Gretarsdottir, Solveig ;
Anderson, Christopher D. ;
Chong, Michael ;
Adams, Hieab HH. ;
Ago, Tetsuro ;
Almgren, Peter ;
Amouyel, Philippe ;
Ay, Hakan ;
Bartz, Traci M. ;
Benavente, Oscar R. ;
Bevan, Steve ;
Boncoraglio, Giorgio B. ;
Brown, Robert D. ;
Butterworth, Aadam S. ;
Carrera, Caty ;
Carty, Cara L. ;
Chen, Wei-Min ;
Cole, John W. ;
Correa, Adolfo ;
Cotlarciuc, Ioanna ;
Cruchaga, Carlos ;
Danesh, John ;
de Bakker, Paul I. W. ;
DeStefano, Anita L. ;
den Hoed, Marcel ;
Duan, Qing ;
Engelter, Stefan T. ;
Falcone, Guido J. ;
Gottesman, Rebecca F. ;
Grewal, Raji P. ;
Gudnason, Vilmundur ;
Gustafsson, Stefan ;
Haessler, Jeffrey ;
Harris, Tamara B. ;
Hassan, Ahamad ;
Havulinna, Aki S. ;
Heckbert, Susan R. ;
Holliday, Elizabeth G. ;
Howard, George ;
Hsu, Fang-Chi ;
Hyacinth, Hyacinth I. ;
Arfan Ikram, M. ;
Ingelsson, Erik ;
Irvin, Marguerite R. ;
Jian, Xueqiu ;
Jiménez-Conde, Jordi ;
Johnson, Julie A. ;
Jukema, J. Wouter ;
Kanai, Masahiro ;
Keene, Keith L. ;
Kissela, Brett M. ;
Kleindorfer, Dawn O. ;
Kooperberg, Charles ;
Kubo, Michiaki ;
Lange, Leslie A. ;
Langefeld, Carl D. ;
Langenberg, Claudia ;
Launer, Lenore J. ;
Lee, Jin-Moo ;
Lemmens, Robin ;
Leys, Didier ;
Lewis, Cathryn M. ;
Lin, Wei-Yu ;
Lindgren, Arne G. ;
Lorentzen, Erik ;
Magnusson, Patrik K. ;
Maguire, Jane ;
Manichaikul, Ani ;
McArdle, Patrick F. ;
Meschia, James F. ;
Mitchell, Braxton D. ;
Mosley, Thomas H. ;
Nalls, Michael A. ;
Ninomiya, Toshiharu ;
O'Donnell, Martin J. ;
Psaty, Bruce M. ;
Pulit, Sara L. ;
Rannikmäe, Kristiina ;
Reiner, Alexander P. ;
Rexrode, Kathryn M. ;
Rice, Kenneth ;
Rich, Stephen S. ;
Ridker, Paul M. ;
Rost, Natalia S. ;
Rothwell, Peter M. ;
Rotter, Jerome I. ;
Rundek, Tatjana ;
Sacco, Ralph L. ;
Sakaue, Saori ;
Sale, Michele M. ;
Salomaa, Veikko ;
Sapkota, Bishwa R. ;
Schmidt, Reinhold ;
Schmidt, Carsten O. ;
Schminke, Ulf ;
Sharma, Pankaj ;
Slowik, Agnieszka ;
Sudlow, Cathie L. M. ;
Tanislav, Christian ;
Tatlisumak, Turgut ;
Taylor, Kent D. ;
Thijs, Vincent N. S. ;
Thorleifsson, Gudmar ;
Thorsteinsdottir, Unnur ;
Tiedt, Steffen ;
Trompet, Stella ;
Tzourio, Christophe ;
van Duijn, Cornelia M. ;
Walters, Matthew ;
Wareham, Nicholas J. ;
Wassertheil-Smoller, Sylvia ;
Wilson, James G. ;
Wiggins, Kerri L. ;
Yang, Qiong ;
Yusuf, Salim ;
Amin, Najaf ;
Aparicio, Hugo S. ;
Arnett, Donna K. ;
Attia, John ;
Beiser, Alexa S. ;
Berr, Claudine ;
Buring, Julie E. ;
Bustamante, Mariana ;
Caso, Valeria ;
Cheng, Yu-Ching ;
Hoan Choi, Seung ;
Chowhan, Ayesha ;
Cullell, Natalia ;
Dartigues, Jean-François ;
Delavaran, Hossein ;
Delgado, Pilar ;
Dörr, Marcus ;
Engström, Gunnar ;
Ford, Ian ;
Gurpreet, Wander S. ;
Hamsten, Anders ;
Heitsch, Laura ;
Hozawa, Aatsushi ;
Ibanez, Laura ;
Ilinca, Andrea ;
Ingelsson, Martin ;
Iwasaki, Motoki ;
Jackson, Rebecca D. ;
Jood, Katarina ;
Jousilahti, Pekka ;
Kaffashian, Sara ;
Kalra, Lalit ;
Kamouchi, Masahiro ;
Kitazono, Takanari ;
Kjartansson, Olafur ;
Kloss, Manja ;
Koudstaal, Peter J. ;
Krupinski, Jerzy ;
Labovitz, Daniel L. ;
Laurie, Cathy C. ;
Levi, Christhoper R. ;
Li, Linxin ;
Lind, Lars ;
Lindgren, Cecilia M. ;
Lioutas, Vasileios ;
Mei Liu, Yong ;
Lopez, Oscar L. ;
Makoto, Hirata ;
Martinez-Majander, Nicolas ;
Matsuda, Koichi ;
Minegishi, Naoko ;
Montaner, Joan ;
Morris, Andrew P. ;
Muiño, Elena ;
Müller-Nurasyid, Martina ;
Norrving, Bo ;
Ogishima, Soichi ;
Parati, Eugenio A. ;
Reddy Peddareddygari, Leema ;
Pedersen, Nancy L. ;
Pera, Joanna ;
Perola, Markus ;
Pezzini, Alessandro ;
Pileggi, Silvana ;
Rabionet, Raquel ;
Riba-Llena, Iolanda ;
Ribasés, Marta ;
Romero, Jose R. ;
Roquer, Jaume ;
Rudd, Anthony G. ;
Sarin, Antti-Pekka ;
Sarju, Ralhan ;
Sarnowski, Chloe ;
Sasaki, Makoto ;
Satizabal, Claudia L. ;
Satoh, Mamoru ;
Sattar, Naveed ;
Sawada, Norie ;
Sibolt, Gerli ;
Sigurdsson, Ásgeir ;
Smith, Albert ;
Sobue, Kenji ;
Soriano-Tárraga, Carolina ;
Stanne, Tara ;
Colin Stine, O. ;
Stott, David J. ;
Strauch, Konstantin ;
Takai, Takako ;
Tanaka, Hideo ;
Tanno, Kozo ;
Teumer, Alexander ;
Tomppo, Liisa ;
Torres-Aguila, Nuria P. ;
Touze, Emmanuel ;
Tsugane, Shoichiro ;
Uitterlinden, Aandre G. ;
Valdimarsson, Einar M. ;
van der Lee, Sven J. ;
Völzke, Henry ;
Wakai, Kenji ;
Weir, David ;
Williams, Stephen R. ;
Wolfe, Charles D.A. ;
Wong, Quenna ;
Xu, Huichun ;
Yamaji, Taiki ;
Sanghera, Dharambir K. ;
Melander, Olle ;
Jern, Christina ;
Strbian, Daniel ;
Fernandez-Cadenas, Israel ;
Longstreth, W.T. ;
Rolfs, Arndt ;
Hata, Jun ;
Woo, Daniel ;
Rosand, Jonathan ;
Pare, Guillaume ;
Hopewell, Jemma C. ;
Saleheen, Danish ;
Stefansson, Kari ;
Worrall, BradfordB. ;
Kittner, Steven J. ;
Seshadri, Sudha ;
Fornage, Myriam ;
Markus, Hugh S. ;
Howson, Joana M. M. ;
Kamatani, Yoichiro ;
Debette, Stephanie ;
Dichgans, Martin ;
Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 -  10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349
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11 p, 1.4 MB |
Sex differential impact of comorbidities in spondyloarthritis : data from COMOSPA study
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Llop, Maria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Moreno Martínez-Losa, Mireia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Arévalo Salaet, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Calvet, Joan (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Berenguer-Llergo, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Dougados, Maxime (Hospital Cochin) ;
Molto, Anna (Hospital Cochin) ;
López-Medina, Clementina (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Universitat Autònoma de Barcelona
To describe and compare the prevalence of comorbidities in female and male patients with spondyloarthritis (SpA) and to assess whether comorbidities had a different impact on disease outcomes in male and female patients. [...]
2024 - 10.1136/rmdopen-2023-003776
RMD Open, Vol. 10 (january 2024)
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20 p, 2.0 MB |
Microvesicles in Atherosclerosis and Angiogenesis : From Bench to Bedside and Reverse
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Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Suades, Rosa (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Arderiu, Gemma (Institut d'Investigació Biomèdica Sant Pau) ;
Peña, Esther (Institut d'Investigació Biomèdica Sant Pau) ;
Chiva-Blanch, Gemma (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Padró, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Atherosclerosis (AT) is a progressive chronic disease involving lipid accumulation, fibrosis, and inflammation in medium and large-sized arteries, and it is the main cause of cardiovascular disease (CVD). [...]
2017 - 10.3389/fcvm.2017.00077
Frontiers in Cardiovascular Medicine, Vol. 4 (18 2017) , p. 77
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6 p, 514.7 KB |
Lifestyle behaviours in patients with established cardiovascular diseases : A European observational study
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Fernández Valverde, Diana Elisabeth (Institut d'Investigació Biomèdica Sant Pau) ;
Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Moral Peláez, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Bulc, Mateja (Ljubljana University) ;
Afonso, Mélanie (Clinique des Universités de Médecine Générale) ;
Akan, Hülya (Yeditepe University) ;
Silva Pinto, Susana (Centre for Health Technology and Services Research (CINTESIS)) ;
Vucak, Jasna (Spec.ord.obiteljske Med) ;
Martins, Carlos (Centre for Health Technology and Services Research (CINTESIS)) ;
Universitat Autònoma de Barcelona
Patients who have experienced a cardiovascular clinical event such as a myocardial infarction or stroke qualify for intensive risk factor evaluation and management. The aim of this study is to explore lifestyle changes as well as the achievement of targets for risk factors in patients with established cardiovascular disease. [...]
2019 - 10.1186/s12875-019-1051-3
BMC family practice, Vol. 20 Núm. 1 (26 2019) , p. 162
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14 p, 902.2 KB |
Attention-deficit/hyperactivity disorder is associated with increased risk of cardiovascular diseases : A systematic review and meta-analysis
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Li, Lin (Karolinska Institutet (Estocolm, Suècia)) ;
Garcia-Argibay, Miguel (Örebro University) ;
Du Rietz, Ebba (Karolinska Institutet (Estocolm, Suècia)) ;
Brikell, Isabell (Aarhus University) ;
Solmi, Marco (University of Southampton) ;
Cortese, Samuele (University of Nottingham) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Chang, Zheng (Karolinska Institutet (Estocolm, Suècia)) ;
Larsson, Henrik (Karolinska Institutet (Estocolm, Suècia)) ;
Yao, Honghui (Karolinska Institutet (Estocolm, Suècia)) ;
Zhang, Le (Karolinska Institutet (Estocolm, Suècia)) ;
Universitat Autònoma de Barcelona
Attention-deficit/hyperactivity disorder (ADHD) often co-occurs with other psychiatric and physical diseases. However, available evidence on associations between ADHD and cardiovascular diseases (CVDs) is mixed. [...]
2023 - 10.1002/jcv2.12158
JCPP Advances, Vol. 3 (april 2023)
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15 p, 867.3 KB |
Cardiovascular disease in type 2 diabetes mellitus : progress toward personalized management
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Ma, Cheng-Xu (The First Clinical Medical College of Lanzhou University) ;
Ma, Xiao-Ni (The First Clinical Medical College of Lanzhou University) ;
Guan, Cong-Hui (The First Clinical Medical College of Lanzhou University) ;
Li, Ying-Dong (College of Integrated Traditional Chinese and Western Medicine. Gansu University of Chinese Medicine) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Fu, Song-Bo (The First Clinical Medical College of Lanzhou University) ;
Universitat Autònoma de Barcelona
Cardiovascular diseases (CVDs) are the main cause of death among patients with type 2 diabetes mellitus (T2DM), particularly in low- and middle-income countries. To effectively prevent the development of CVDs in T2DM, considerable effort has been made to explore novel preventive approaches, individualized glycemic control and cardiovascular risk management (strict blood pressure and lipid control), together with recently developed glucose-lowering agents and lipid-lowering drugs. [...]
2022 - 10.1186/s12933-022-01516-6
Cardiovascular diabetology, Vol. 21 Núm. 1 (december 2022) , p. 74
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12 p, 16.7 MB |
Practical outpatient management of worsening chronic heart failure
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Girerd, Nicolas (Université de Lorraine) ;
Mewton, Nathan (University Claude Bernard Lyon) ;
Tartière, Jean-Michel (Hôpital Sainte-Musse) ;
Guijarro, Damien (Université de Nantes) ;
Jourdain, Patrick (Assistance Publique-Hôpitaux de Paris) ;
Damy, Thibaud (CHU d'Henri-Mondor) ;
Lamblin, Nicolas (Université de Lille) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pellicori, Pierpaolo (University of Glasgow) ;
Januzzi, James L. (Harvard Medical School) ;
Rossignol, Patrick (Université de Lorraine) ;
Roubille, François (CHU de Montpellier) ;
Universitat Autònoma de Barcelona
Management of worsening heart failure (WHF) has traditionally been hospital-based, but with the rising burden of heart failure (HF), the pressure on healthcare systems exerted by this disease necessitates a different strategy than long (and costly) hospital stays. [...]
2022 - 10.1002/ejhf.2503
European Journal of Heart Failure, Vol. 24 (april 2022) , p. 750-761
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44 p, 3.5 MB |
Recomendaciones preventivas cardiovasculares. Actualización PAPPS 2022
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Orozco-Beltrán, Domingo (Medicina Familiar y Comunitaria, Unidad de Investigación Centro de Salud Cabo Huertas, Departamento San Juan de Alicante. Departamento de Medicina Clínica, Universidad Miguel Hernández, San Juan de Alicante, España) ;
Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Banegas Banegas, José Ramón (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública) ;
Gil Guillén, Vicente F. (Universidad Miguel Hernández) ;
Cebrián-Cuenca, Ana M (Instituto Murciano de Investigación Biosanitaria) ;
Martín Rioboó, Enrique (Hospital Reina Sofía Córdoba) ;
Jordá Baldó, Ariana (Centro de Salud San Miguel (Extremadura)) ;
Vicuña, Johanna (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Navarro Pérez, Jorge (Universitat de València)
Se presentan las recomendaciones del Programa de Actividades Preventivas y Promoción de la Salud (PAPPS) de la Sociedad Española de Medicina de Familia y Comunitaria (semFYC), para la prevención de las enfermedades cardiovasculares (V). [...]
2022 - 10.1016/j.aprim.2022.102444
Atencion Primaria, Vol. 54 (november 2022)
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12 p, 2.6 MB |
Statement of the Spanish interdisciplinary vascular prevention committee on the updated European guidelines on cardiovascular disease prevention 2021 Comentario del CEIPV a las nuevas guías europeas de prevención cardiovascular 2021
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Brotons, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Camafort, Miguel (Sociedad Española de Medicina Interna) ;
Castellanos, María del Mar (Sociedad Española de Neurología) ;
Clará Velasco, Alberto (Sociedad Española de Angiología y Cirugía Vascular) ;
Cortés, Olga (Asociación Española de Pediatría de Atención Primaria) ;
Díaz Rodríguez, Ángel (Sociedad Española de Médicos de Atención Primaria (SEMERGEN)) ;
Elosua, Roberto (Sociedad Española de Epidemiología) ;
Gorostidi, Manuel (Sociedad Española de Nefrología) ;
Hernández, Antonio M. (Sociedad Española de Diabetes) ;
Herranz, María (Federación de Asociaciones de Enfermería Comunitaria y Atención Primaria (FAECAP)) ;
Justo, Soledad (Ministerio de Sanidad) ;
Lahoz, Carlos (Sociedad Española de Medicina Interna) ;
Niño, Pilar (Sociedad Española de Medicina y Seguridad del Trabajo) ;
Pallarés-Carratalá, Vicente (Sociedad Española de Médicos de Atención Primaria (SEMERGEN)) ;
Pedro-Botet, Juan (Sociedad Española de Arteriosclerosis) ;
Pérez Pérez, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Royo-Bordonada, Miguel Ángel (Instituto de Salud Carlos III) ;
Santamaría, Rafael (Sociedad Española de Nefrología) ;
Tresserras, Ricard (Sociedad Española de Salud Pública y Administración Sanitaria (SESPAS)) ;
Zamora, Alberto (Sociedad Española de Arteriosclerosis) ;
Zuza, Inés (Ministerio de Sanidad) ;
Armario, Pedro (Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial.)
We present the Spanish adaptation of the 2021 European Guidelines on Cardiovascular Disease (CVD) prevention in clinical practice. The current guidelines besides the individual approach greatly emphasize on the importance of population level approaches to the prevention of cardiovascular diseases. [...]
2022 - 10.20960/angiologia.00411
Angiologia, Vol. 74 Núm. 5 (septiembre 2022) , p. 237-248
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