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Resultados globales: 9 registros encontrados en 0.07 segundos.
Artículos, Encontrados 8 registros
Libros y colecciones, Encontrados 1 registros
Artículos Encontrados 8 registros  
1.
12 p, 2.5 MB The intrinsic chaperone network of Arabidopsis stem cells confers protection against proteotoxic stress / Llamas, Ernesto (University of Cologne) ; Torres Montilla, Salvador (Centre de Recerca en Agrigenòmica) ; Lee, Hyun Ju (University of Cologne) ; Barja, Maria Victoria (Centre de Recerca en Agrigenòmica) ; Schlimgen, Elena (University of Cologne) ; Dunken, Nick (University of Cologne) ; Wagle, Prerana (University of Cologne) ; Werr, Wolfgang (University of Cologne) ; Zuccaro, Alga (University of Cologne) ; Rodríguez Concepción, Manuel (Centre de Recerca en Agrigenòmica) ; Vilchez, David (University Hospital Cologne)
The biological purpose of plant stem cells is to maintain themselves while providing new pools of differentiated cells that form organs and rejuvenate or replace damaged tissues. Protein homeostasis or proteostasis is required for cell function and viability. [...]
2021 - 10.1111/acel.13446
Aging Cell, Vol. 20, Issue 8 (July 2021) , art. e13446  
Registro completo - Creative Commons
2.
24 p, 4.6 MB Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach / Dublang, Leire (Universidad del País Vasco. Departamento de Bioquímica y Biología Molecular) ; Underhaug, Jarl (University of Bergen. Department of Chemistry) ; Flydal, Marte I. (University of Bergen. Department of Biomedicine) ; Velasco-Carneros, Lorea (Universidad del País Vasco. Departamento de Bioquímica y Biología Molecular) ; Maréchal, Jean-Didier (Universitat Autònoma de Barcelona. Departament de Química) ; Moro, Fernando (Universidad del País Vasco. Departamento de Bioquímica y Biología Molecular) ; Boyano, Maria Dolores (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Martinez, Aurora (University of Bergen. Department of Biomedicine) ; Muga, Arturo (Universidad del País Vasco. Departamento de Bioquímica y Biología Molecular)
High levels of Heat shock proteins (Hsps) in specific cancers are usually linked to a poor prognosis, tumor progression, invasiveness, and resistance to treatment. Chaperone inhibition could therefore be toxic for cancer cells due to their high dependence on chaperone activity to survive. [...]
2021 - 10.3390/cancers13122936
Cancers, Vol. 13, Issue 12 (June 2021) , art. 2936  
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3.
13 p, 1.1 MB Post-Genomic Methodologies and Preclinical Animal Models : Chances for the Translation of Cardioprotection to the Clinic / Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ; Mendieta, Guiomar (Hospital Clínic i Provincial de Barcelona) ; Ben-Aicha Gonzalez, Soumaya (Institut d'Investigació Biomèdica Sant Pau) ; Vilahur, Gemma (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Universitat Autònoma de Barcelona
Although many cardioprotective strategies have demonstrated benefits in animal models of myocardial infarction, they have failed to demonstrate cardioprotection in the clinical setting highlighting that new therapeutic target and treatment strategies aimed at reducing infarct size are urgently needed. [...]
2019 - 10.3390/ijms20030514
International journal of molecular sciences, Vol. 20 (january 2019)  
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4.
17 p, 1.2 MB Human α-galactosidase a mutants : Priceless tools to develop novel therapies for fabry disease / Modrego, Andrea (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Amaranto, Marilla (Universidad Nacional de Córdoba (Argentina)) ; Godino, Agustina (Universidad Nacional de Córdoba (Argentina)) ; Mendoza, Rosa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Barra, José Luis (Universidad Nacional de Córdoba (Argentina)) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Fabry disease (FD) is a lysosomal storage disease caused by mutations in the gene for the α-galactosidase A (GLA) enzyme. The absence of the enzyme or its activity results in the accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb3), in different tissues, leading to a wide range of clinical manifestations. [...]
2021 - 10.3390/ijms22126518
International journal of molecular sciences, Vol. 22, Issue 12 (June 2021) , art. 6518  
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5.
3 p, 161.8 KB Editorial : protein solubility and aggregation in bacteria / Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
The Editorial on the research topic protein solubility and aggregation in bacteria.
2016 - 10.3389/fmicb.2016.01178
Frontiers in microbiology, Vol. 7 (July 2016) , art. 1178  
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6.
7 p, 1.9 MB Manipulation of plastidial protein quality control components as a new strategy to improve carotenoid contents in tomato fruit / D'Andrea, Lucio (Centre de Recerca en Agrigenòmica) ; Rodríguez Concepción, Manuel (Centre de Recerca en Agrigenòmica)
Carotenoids such as β-carotene (pro-vitamin A) and lycopene accumulate at high levels during tomato (Solanum lycopersicum L. ) fruit ripening, contributing to the characteristic color and nutritional quality of ripe tomatoes. [...]
2019 - 10.3389/fpls.2019.01071
Frontiers in plant science, Vol. 10 (September 2019) , art. 1071  
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7.
11 p, 2.2 MB Interference with Clp protease impairs carotenoid accumulation during tomato fruit ripening / D'Andrea, Lucio (Centre de Recerca en Agrigenòmica) ; Simon-Moya, Miquel (Centre de Recerca en Agrigenòmica) ; Llorente, Briardo (Centre de Recerca en Agrigenòmica) ; Llamas, Ernesto (Centre de Recerca en Agrigenòmica) ; Marro, Mónica (Institut de Ciències Fotòniques) ; Loza-Alvarez, Pablo (Institut de Ciències Fotòniques) ; Li, Li (Robert W. Holley Center for Agriculture and Health) ; Rodríguez Concepción, Manuel (Centre de Recerca en Agrigenòmica)
Profound metabolic and structural changes are required for fleshy green fruits to ripen and become colorful and tasty. In tomato (Solanum lycopersicum), fruit ripening involves the differentiation of chromoplasts, specialized plastids that accumulate carotenoid pigments such as β-carotene (pro-vitamin A) and lycopene. [...]
2018 - 10.1093/jxb/erx491
Journal of experimental botany, Vol. 69 issue 7 (2018) , p. 1557-1568  
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8.
22 p, 99.8 KB Molecular Pathology of Lewy Body Diseases / Beyer, Katrin (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domingo-Sàbat, Montse (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ariza Fernández, A.. (Aurelio) (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques)
Lewy body diseases are characterized by the presence of Lewy bodies, alphasynuclein(AS)-positive inclusions in the brain. Since their main component is conformationally modified AS, aggregation of the latter is thought to be a key pathogenic event in these diseases. [...]
2009 - 10.3390/ijms10030724
International journal of molecular sciences, Vol. 10 (2009) , p. 724-745  
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Libros y colecciones Encontrados 1 registros  
1.
24 p, 556.9 KB Detection and elimination of cellular bottlenecks in protein-producing yeasts / Zahrl, Richard J. (University of Natural Resources and Life Sciences. Department of Biotechnology (Austria)) ; Gasser, Brigitte (University of Natural Resources and Life Sciences. Department of Biotechnology (Austria)) ; Mattanovich, Diethard (University of Natural Resources and Life Sciences. Department of Biotechnology (Austria)) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Yeasts are efficient cell factories and are commonly used for the production of recombinant proteins for biopharmaceutical and industrial purposes. For such products high levels of correctly folded proteins are needed, which sometimes requires improvement and engineering of the expression system. [...]
New York : Humana, 2019 (Methods in Molecular Biology ; 1923) - 10.1007/978-1-4939-9024-5_2
Recombinant Protein Production in Yeast, 2019, p. 75-95  
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