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9 p, 612.9 KB |
Bariatric surgery increases the rate of major fracture : self-controlled case series study in Clinical Practice Research Datalink
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Robinson, Danielle E. (University of Oxford) ;
Douglas, Ian (London School of Hygiene & Tropical) ;
Tan, Garry D. (The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre) ;
Delmestri, Antonella (University of Oxford) ;
Judge, Andrew (University of Bristol) ;
Cooper, Cyrus (University of Oxford) ;
Javaid, M. Kassim (University of Southampton) ;
Strauss, Victoria Y. (University of Oxford) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
Conflicting results exist about the relationship between bariatric surgery and fracture risk. Also, prediction of who is at increased risk of fracture after bariatric surgery is not currently available. [...]
2021 -  10.1002/jbmr.4405
Journal of Bone and Mineral Research, Vol. 36 (july 2021) , p. 2153-2161
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11 p, 548.2 KB |
Estimating the Incidence and Key Risk Factors of Cardiovascular Disease in Patients at High Risk of Imminent Fracture Using Routinely Collected Real-World Data From the
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Pineda-Moncusí, Marta (University of Oxford) ;
El-Hussein, Leena (University of Oxford) ;
Delmestri, Antonella (University of Oxford) ;
Cooper, Cyrus (University of Southampton) ;
Moayyeri, Alireza (UCB Biopharma Sprl) ;
Libanati, Cesar (UCB Biopharma Sprl) ;
Toth, Emese (UCB Biopharma Sprl) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Khalid, Sara (University of Oxford) ;
Universitat Autònoma de Barcelona
The objective of this work was to estimate the incidence rate of cardiovascular disease (CVD) events (myocardial infarction, stroke, or CVD death) at 1 year among three cohorts of patients at high risk of fracture (osteoporosis, previous fracture, and anti-osteoporosis medication) and to identify the key risk factors of CVD events in these three cohorts. [...]
2022 - 10.1002/jbmr.4648
Journal of Bone and Mineral Research, Vol. 37 (september 2022) , p. 1986-1996
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3.
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24 p, 1.5 MB |
Is it time to consider population screening for fracture risk in postmenopausal women? A position paper from the International Osteoporosis Foundation Epidemiology/Quality of Life Working Group
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Chotiyarnwong, P. (Mahidol University) ;
McCloskey, E. V. (University of Sheffield) ;
Harvey, N. C. (University of Southampton) ;
Lorentzon, M. (Australian Catholic University) ;
Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona) ;
Abrahamsen, Bo (Holbæk Hospital (Dinamarca)) ;
Adachi, Jonathan D (St Joseph's Healthcare-McMaster University) ;
Borgström, F. (Karolinska Institutet (Estocolm, Suècia)) ;
Bruyère, Olivier (Université de Liège) ;
Carey, J. J. (Galway University Hospitals) ;
Clark, P. (Universidad Nacional Autónoma de México) ;
Cooper, Cyrus (University of Southampton) ;
Curtis, E. M. (University of Southampton) ;
Dennison, E. M (University of Southampton) ;
Diaz-Curiel, Manuel (Hospital Universitario Fundación Jiménez Díaz) ;
Dimai, Hans Peter (Medical University of Graz) ;
Grigorie, D. (National Institute of Endocrinology) ;
Hiligsmann, M. (Maastricht University) ;
Khashayar, P. (Imec and Ghent University) ;
Lewiecki, E. M. (New Mexico Clinical Research & Osteoporosis Center) ;
Lips, P. (Vrije Universiteit Amsterdam) ;
Lorenc, R. S. (Multidisciplinary Osteoporosis Forum (Polònia)) ;
Ortolani, S. (IRCCS Istituto Auxologico (Itàlia)) ;
Papaioannou, A. (GERAS Centre for Aging Research (Canadà)) ;
Silverman, Stuart (Cedars-Sinai Medical Center) ;
Sosa-Henríquez, Manuel (Universidad de Las Palmas de Gran Canaria) ;
Szulc, P. (Hôpital Edouard Herriot (França)) ;
Ward, K. A. (University of Southampton) ;
Yoshimura, N. (University of Tokyo) ;
Kanis, John A (Australian Catholic University)
The IOF Epidemiology and Quality of Life Working Group has reviewed the potential role of population screening for high hip fracture risk against well-established criteria. The report concludes that such an approach should strongly be considered in many health care systems to reduce the burden of hip fractures. [...]
2022 - 10.1007/s11657-022-01117-6
Archives of Osteoporosis, Vol. 17 (june 2022)
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4.
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2 p, 536.6 KB |
Correction to : Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease: an open cohort multivariable and propensity score analysis from Funen, Denmark
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Ali, M. Sanni (Saint Paul Hospital Millennium Medical College. Department of Public Health) ;
Ernst, Martin (University of Southern Denmark. Department of Public Health, Clinical Pharmacology and Pharmacy) ;
Robinson, Danielle E. (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Caskey, Fergus (University of Bristol. Population Health Sciences) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit) ;
Ben-Shlomo, Yoav (University of Bristol. Population Health Sciences) ;
Nybo, Mads (Odense University Hospital (Dinamarca)) ;
Rubin, Katrine H. (University of Southern Denmark. Department of Health) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit) ;
Javaid, M. K. (MRC Lifecourse Epidemiology Unit) ;
Hermann, Anne P. (Odense University Hospital (Dinamarca)) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
2021 - 10.1007/s11657-021-01001-9
Archives of Osteoporosis, Vol. 16 (september 2021)
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5.
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11 p, 810.9 KB |
The treatment gap after major osteoporotic fractures in Denmark 2005-2014 : a combined analysis including both prescription-based and hospital-administered anti-osteoporosis medications
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Skjødt, M. K. (Holbæk Hospital (Dinamarca)) ;
Ernst, M. T. (University of Southern Denmark. Department of Public Health, Clinical Pharmacology, Pharmacy and Environmental Medicine) ;
Khalid, Sara (Oxford University Hospitals. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Libanati, C. (UCB Pharma) ;
Cooper, Cyrus (University of Southampton) ;
Delmestri, Antonella (Oxford University Hospitals. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Rubin, K. H. (University of Southern Denmark) ;
Javaid, M. K. (Oxford University Hospitals. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Martínez-Laguna, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Prieto-Alhambra, Daniel (Oxford University Hospitals. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Abrahamsen, Bo (Oxford University Hospitals. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Universitat Autònoma de Barcelona
This study demonstrates a substantial and persistent anti-osteoporosis treatment gap in men and women ≥50 years old who sustained major osteoporotic fracture(s) between 2005 and 2014 in Denmark. This was not substantially reduced by including hospital-administered anti-osteoporosis treatments. [...]
2021 - 10.1007/s00198-021-05890-x
Osteoporosis International, Vol. 32 (march 2021) , p. 1961-1971
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12 p, 944.6 KB |
Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease : an open cohort multivariable and propensity score analysis from Funen, Denmark
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Ali, M. Sanni (London School of Hygiene and Tropical Medicine. Department of Non-communicable Disease Epidemiology) ;
Ernst, Martin (University of Southern Denmark. Department of Public Health, Clinical Pharmacology and Pharmacy) ;
Robinson, Danielle E. (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ;
Caskey, Fergus (University of Bristol. Population Health Sciences) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit) ;
Ben-Shlomo, Yoav (University of Bristol. Population Health Sciences) ;
Nybo, Mads (Odense University Hospital (Dinamarca)) ;
Rubin, Katrine H. (University of Southern Denmark. Department of Health) ;
Judge, Andrew (MRC Lifecourse Epidemiology Unit) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit) ;
Javaid, M. K. (MRC Lifecourse Epidemiology Unit) ;
Hermann, Anne P. (Odense University Hospital (Dinamarca)) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
Bisphosphonates are contraindicated in moderate-to-severe chronic kidney disease patients. However, they are used to prevent fragility fractures in patients with impaired kidney function, despite a lack of evidence on their effects on bone density in these patients. [...]
2020 - 10.1007/s11657-020-00746-z
Archives of Osteoporosis, Vol. 15 (june 2020)
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8 p, 535.7 KB |
The impact of rheumatoid arthritis on the risk of adverse events following joint replacement : a real-world cohort study
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Burn, Edward (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Edwards, Christopher J. (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Murray, David W. (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Silman, Alan (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK) ;
Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Arden, N. K (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Pinedo-Villanueva, Rafael (MRC Lifecourse Epidemiology Unit, Southampton University, Southampton, UK) ;
Universitat Autònoma de Barcelona
To assess whether rheumatoid arthritis (RA) is associated with a greater risk of adverse events following total knee replacement (TKR) and total hip replacement (THR) than osteoarthritis (OA). Individuals with a diagnosis of RA or OA were identified using primary care records. [...]
2018 - 10.2147/CLEP.S160347
Clinical Epidemiology, Vol. 10 (june 2018) , p. 697-704
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16 p, 967.2 KB |
Assessment of Cardiovascular Safety of Anti-Osteoporosis Drugs
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Fuggle, N. R. (University of Southampton) ;
Cooper, Cyrus (University of Oxford) ;
Harvey, N. C. (University of Southampton) ;
Al-Daghri, Nasser (King Saud University) ;
Brandi, Maria Luisa (University Hospital of Florence) ;
Bruyère, Olivier (WHO Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Aging, Liège, Belgium) ;
Cano Sánchez, Antonio (University of Valencia) ;
Dennison, E. M. (University of Southampton) ;
Díez Pérez, Adolfo (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Kaufman, J.-M. (Universitair Ziekenhuis Gent) ;
Palacios, S. (The Palacios Institute of Women's Health, Madrid) ;
Prieto-Alhambra, D. (University of Oxford) ;
Rozenberg, S. (CHU St Pierre, Bruxelles) ;
Thomas, T. (CHU de Saint-Etienne, France) ;
Tremollieres, F. (Toulouse University Hospital) ;
Rizzoli, R. (Hôpitaux Universitaires Genève) ;
Kanis, John A (Australian Catholic University) ;
Reginster, Jean-Yves (King Saud University) ;
Universitat Autònoma de Barcelona
The incidence of osteoporosis and cardiovascular disease increases with age, and there are potentially shared mechanistic associations between the two conditions. It is therefore highly relevant to understand the cardiovascular implications of osteoporosis medications. [...]
2020 - 10.1007/s40265-020-01364-2
Drugs, Vol. 80 (july 2020) , p. 1537-1552
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10 p, 780.0 KB |
Secular trends in the initiation of therapy in secondary fracture prevention in Europe : a multi-national cohort study including data from Denmark, Catalonia, and the United Kingdom
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Skjødt, M. K. (Odense University Hospital (Dinamarca)) ;
Khalid, Sara (Oxford University Hospitals. Nuffield Orthopaedic Centre) ;
Ernst, M. (University of Southern Denmark. Department of Public Health, Clinical Pharmacology and Pharmacy) ;
Rubin, K. H. (Odense University Hospital (Dinamarca)) ;
Martínez-Laguna, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Delmestri, Antonella (Oxford University Hospitals. Nuffield Orthopaedic Centre) ;
Javaid, M. K. (Oxford University Hospitals. Nuffield Orthopaedic Centre) ;
Cooper, Cyrus (University Hospital Southampton NHS Foundation Trust (Regne Unit)) ;
Libanati, C. (UCB Pharma) ;
Toth, E. (UCB Pharma) ;
Abrahamsen, Bo (Oxford University Hospitals. Nuffield Orthopaedic Centre) ;
Prieto-Alhambra, Daniel (Oxford University Hospitals. Nuffield Orthopaedic Centre)
This paper demonstrates a large post-fracture anti-osteoporosis treatment gap in the period 2005 to 2015. The gap was stable in Denmark at around 88-90%, increased in Catalonia from 80 to 88%, and started to increase in the UK towards the end of our study. [...]
2020 - 10.1007/s00198-020-05358-4
Osteoporosis International, Vol. 31 (march 2020) , p. 1535-1544
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15 p, 1.4 MB |
Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data : a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database
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Khalid, Sara (University of Oxford. NIHR Biomedical Research Centre) ;
Calderon-Larrañaga, Sara (Family and Community Medicine Teaching Unit of Granada. Cartuja University Health Centre. Andalusian Health Service (SAS), Granada, Spain) ;
Hawley, Samuel (University of Oxford. NIHR Biomedical Research Centre) ;
Ali, M. Sanni (London School of Hygiene and Tropical Medicine, London, United Kingdom) ;
Judge, Andrew (Bristol NIHR Biomedical Research Centre (Bristol, Regne Unit)) ;
Arden, N. K (University of Oxford. Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis) ;
van Staa, Tjeerd (Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands) ;
Cooper, Cyrus (NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom) ;
Javaid, Muhammad Kassim (University of Oxford. NIHR Biomedical Research Centre) ;
Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Universitat Autònoma de Barcelona
This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. We investigated two primary care records databases covering UK National Health Service (Clinical Practice Research Datalink, CPRD) and Catalan healthcare (Information System for Research in Primary Care, SIDIAP) patients during 1995-2014 and 2006-2014, respectivey. [...]
2018 - 10.2147/CLEP.S164112
Clinical Epidemiology, Vol. 10 (october 2018) , p. 1417-1431
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