Resultados globales: 7 registros encontrados en 0.02 segundos.
Artículos, Encontrados 7 registros
Artículos Encontrados 7 registros  
1.
18 p, 4.0 MB Targeting OGG1 arrests cancer cell proliferation by inducing replication stress / Visnes, T. (Department of Biotechnology and Nanomedicine. Sintef Industry) ; Benítez-Buelga, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Cázares-Körner, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Sanjiv, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hanna, B.M.F. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Mortusewicz, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rajagopal, V. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Albers, J.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Hagey, D.W. (Department of Laboratory Medicine. Karolinska Institutet) ; Bekkhus, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Eshtad, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Baquero, J.M. (Human Genetics Group. Spanish National Cancer Research Centre (CNIO)) ; Masuyer, G. (Department of Pharmacy and Pharmacology. Centre for Therapeutic Innovation. University of Bath) ; Wallner, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Müller, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pham, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Göktürk, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rasti, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Suman, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sarno, A. (Department of Environment and New Resources. Sintef Ocean) ; Wiita, E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Homan, E.J. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Karsten, S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Marimuthu, K. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Michel, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Koolmeister, T. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Scobie, M. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Loseva, O. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Almlöf, I. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Unterlass, J.E. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Pettke, A. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Boström, J. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Pandey, M. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Gad, H. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Herr, P. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Jemth, A.S. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; El Andaloussi, S. (Department of Laboratory Medicine. Karolinska Institutet) ; Kalderén, C. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Rodriguez-Perales, S. (Molecular Cytogenetics Group. Human Cancer Genetics Program. Spanish National Cancer Research Centre (CNIO)) ; Benítez, J. (Spanish Network on Rare Diseases (CIBERER)) ; Krokan, H.E. (The Liaison Committee for Education. Research and Innovation in Central Norway) ; Altun, M. (Science for Life Laboratory. Division of Clinical Physiology. Department of Laboratory Medicine. Karolinska Institutet) ; Stenmark, P. (Department of Experimental Medical Science. Lund University) ; Berglund, U.W. (Science for Life Laboratory. Department of Oncology and Pathology. Karolinska Institutet) ; Helleday, T. (Weston Park Cancer Centre. Department of Oncology and Metabolism. University of Sheffield) ; Universitat Autònoma de Barcelona
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e. g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. [...]
2021 - 10.1093/nar/gkaa1048
Nucleic acids research, Vol. 48 Núm. 21 (february 2021) , p. 12234-12251  
2.
25 p, 3.6 MB Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control / Oriol-Tordera, Bruna (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Duran-Castells, Clara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ganoza, C. (Alberto Hurtado School of Medicine. Universidad Peruana Cayetano Heredia) ; Sanchez, J. (Centro de Investigaciones Tecnológicas. Biomédicas y Medioambientales. CITBM) ; Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Calle, M.L. (University of Vic-Central University of Catalonia) ; Sánchez-Pla, Àlex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
GWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. [...]
2020 - 10.1371/JOURNAL.PPAT.1008678
PLoS pathogens, Vol. 16 Núm. 8 (june 2020) , p. e1008678  
3.
10 p, 1.5 MB P110 and P140 cytadherence-related proteins are negative effectors of terminal organelle duplication in Mycoplasma genitalium / Quijada Pich, Oscar (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Burgos Castellanos, Raul (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Querol Murillo, Enrique (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Piñol Ribas, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Background: The terminal organelle is a complex structure involved in many aspects of the biology of mycoplasmas such as cell adherence, motility or cell division. Mycoplasma genitalium cells display a single terminal organelle and duplicate this structure prior to cytokinesis in a coordinated manner with the cell division process. [...]
2009 - 10.1371/journal.pone.0007452
PloS one, Vol. 4 issue 10 (2009) , art. e7452  
4.
38 p, 5.4 MB Differences in firing efficiency, chromatin and transcription underlie the developmental plasticity of the Arabidopsis DNA replication origins / Sequeira-Mendes, Joana (Centro de Biología Molecular Severo Ochoa) ; Vergara, Zaida (Centro de Biología Molecular Severo Ochoa) ; Peiró, Ramon (Centro de Biología Molecular Severo Ochoa) ; Morata, Jordi (Centre de Recerca en Agrigenòmica) ; Aragüez, Irene (Centro de Biología Molecular Severo Ochoa) ; Costas, Celina (Centro de Biología Molecular Severo Ochoa) ; Méndez Giráldez, Raúl (Centro de Biología Molecular Severo Ochoa) ; Casacuberta i Suñer, Josep M. 1962- (Centre de Recerca en Agrigenòmica) ; Bastolla, Ugo (Centro de Biología Molecular Severo Ochoa) ; Gutiérrez, Crisanto (Centro de Biología Molecular Severo Ochoa)
Eukaryotic genome replication depends on thousands of DNA replication origins (ORIs). A major challenge is to learn ORI biology in multicellular organisms in the context of growing organs to understand their developmental plasticity. [...]
2019 - 10.1101/gr.240986.118
Genome research, Vol. 29, Issue 5 (May 2019) , p. 784-797  
5.
47 p, 1.4 MB The circadian clock sets the time of DNA replication licensing to regulate growth in Arabidopsis / Fung Uceda, Jorge Alberto (Centre de Recerca en Agrigenòmica) ; Lee, Kyounghee (Sungkyunkwan University. Department of Biological Sciences) ; Seo, Pil Joon (Sungkyunkwan University. Department of Biological Sciences) ; Polyn, Stefanie (Universiteit Gent. Department of Plant Biotechnology and Bioinformatics) ; De Veylder, Lieven (Universiteit Gent. Department of Plant Biotechnology and Bioinformatics) ; Mas, Paloma (Centre de Recerca en Agrigenòmica)
The circadian clock and cell cycle as separate pathways have been well documented in plants. Elucidating whether these two oscillators are connected is critical for understanding plant growth. We found that a slow-running circadian clock decelerates the cell cycle and, conversely, a fast clock speeds it up. [...]
2018 - 10.1016/j.devcel.2018.02.022
Developmental Cell, Vol. 45, issue 1 (April 2018) , p. 101-113  
6.
11 p, 1.4 MB Retrotransposons are specified as DNA replication origins in the gene-poor regions of Arabidopsis heterochromatin / Vergara, Zaida (Centro de Biología Molecular Severo Ochoa) ; Sequeira-Mendes, Joana (Centro de Biología Molecular Severo Ochoa) ; Morata, Jordi (Centre de Recerca en Agrigenòmica) ; Peiró, Ramón (Centro de Biología Molecular Severo Ochoa) ; Hénaff, Elizabeth (Centre de Recerca en Agrigenòmica) ; Costas, Celina (Centro de Biología Molecular Severo Ochoa) ; Casacuberta i Suñer, Josep M. 1962- (Centre de Recerca en Agrigenòmica) ; Gutierrez, Crisanto (Centro de Biología Molecular Severo Ochoa)
Genomic stability depends on faithful genome replication. This is achieved by the concerted activity of thousands of DNA replication origins (ORIs) scattered throughout the genome. The DNA and chromatin features determining ORI specification are not presently known. [...]
2017 - 10.1093/nar/gkx524
Nucleic acids research, Vol. 45, issue 14 (Aug. 2017) , p. 8358-8368  
7.
10 p, 1.3 MB Altering the Ad5 packaging domain affects the maturation of the ad particles / Alba Fernández, Raúl (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i Teràpia Gènica (CBATEG)) ; Cots, Dan (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i Teràpia Gènica (CBATEG)) ; Ostapchuk, Philomena (Stony Brook University. Department of Molecular Genetics and Microbiology (Nova York, Estats Units d'Amèrica)) ; Bosch i Merino, Assumpció (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Hearing, Patrick (Stony Brook University. Department of Molecular Genetics and Microbiology (Nova York, Estats Units d'Amèrica)) ; Chillón Rodríguez, Miguel (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i Teràpia Gènica (CBATEG))
We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain. These novel helper viruses have a significantly delayed viral life cycle and a severe packaging impairment, regardless of the presence of PhiC31 recombinase. [...]
2011 - 10.1371/journal.pone.0019564
PloS one, Vol. 6, Issue 5 (May 2011) , p. e19564  

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