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9 p, 262.4 KB |
Polygenic association between attention-deficit/hyperactivity disorder liability and cognitive impairments
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Vainieri, Isabella (Institute of Psychiatry (Regne Unit)) ;
Martin, Joanna (Cardiff University (Regne Unit)) ;
Rommel, Anna-Sophie (Public Health at the Icahn School of Medicine at Mount Sinai) ;
Asherson, Philip (King's College London) ;
Banaschewski, Tobias (University of Heidelberg) ;
Buitelaar, Jan (Radboud University Medical Centre) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Crosbie, Jennifer (University of Toronto) ;
Faraone, Stephen V. (SUNY Upstate Medical University) ;
Franke, Barbara (Radboud University Medical Center) ;
Loo, Sandra K. (Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine at UCLA) ;
Miranda, Ana (Universitat de València) ;
Manor, Iris (Tel-Aviv University) ;
Oades, Robert D. (University of Duisburg-Essen) ;
Purves, Kirstin L. (Institute of Psychiatry, Psychology and Neuroscience) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona) ;
Ribasés Haro, Marta (Universitat de Barcelona) ;
Roeyers, Herbert (Ghent University) ;
Rothenberger, Aribert (University Medical Center Göttingen) ;
Schachar, Russell (University of Toronto) ;
Sergeant, Joseph (Vrije Universiteit) ;
Steinhausen, Hans-Christoph (Centre of Child and Adolescent Mental Health) ;
Vuijk, Pieter J. (Massachusetts General Hospital (Estats Units d'Amèrica)) ;
Doyle, Alysa E. (Harvard Medical School) ;
Kuntsi, Jonna (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
A recent genome-wide association study (GWAS) identified 12 independent loci significantly associated with attention-deficit/hyperactivity disorder (ADHD). Polygenic risk scores (PRS), derived from the GWAS, can be used to assess genetic overlap between ADHD and other traits. [...]
2022 -  10.1017/S0033291720005218
Psychological Medicine, Vol. 52 (october 2022) , p. 3150-3158
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10 p, 2.1 MB |
Shared genetic background between children and adults with attention deficit/hyperactivity disorder
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Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Demontis, Ditte (Center for Genomics and Personalized Medicine, Aarhus, Denmark) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zayats, Tetyana (Broad Institute of MIT and Harvard) ;
Klein, Marieke (University Medical Center Utrecht) ;
Mota, Nina Roth (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Weber, Heike (University Hospital of Frankfurt (Alemanya)) ;
García-Martinez, Iris (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pagerols, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arribas, Lorena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Richarte, Vanesa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corrales, Montserrat (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fadeuilhe, Christian (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Martin, Gemma Español (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Almos, Peter (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Doyle, Alysa E. (Harvard Medical School. Department of Psychiatry) ;
Grevet, Eugenio Horacio (Universidade Federal do Rio Grande do Sul. Department of Psychiatry, Faculty of Medicine) ;
Grimm, Oliver (University Hospital of Frankfurt (Alemanya)) ;
Halmøy, Anne (Haukeland University Hospital (Bergen, Noruega)) ;
Hoogman, Martine (Radboud University Medical Center. Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour) ;
Hutz, Mara (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Jacob, Christian P. (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Kittel-Schneider, Sarah (University Hospital of Frankfurt (Alemanya)) ;
Knappskog, Per M. (University of Bergen. Department of Clinical Science) ;
Lundervold, Astri J. (University of Bergen. Department of Biological and Medical Psychology) ;
Rivero, Olga (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Rovaris, Diego Luiz (University of São Paulo. Department of Physiology and Biophysics, Institute of Biomedical Sciences) ;
Salatino-Oliveira, Angelica (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
da Silva, Bruna Santos (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Svirin, Evgeniy (IM Sechenov First Moscow State Medical University. Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine) ;
Sprooten, Emma (Radboud University Medical Centre. Department of Cognitive Neuroscience) ;
Strekalova, Tatyana (Maastricht University. Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS)) ;
Arias-Vásquez, Alejandro (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Sonuga-Barke, Edmund J. S. (Aarhus University. Department of Child and Adolescent Psychiatry) ;
Asherson, Philip (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Bau, Claiton Henrique Dotto (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Buitelaar, Jan (Karakter Child and Adolescent Psychiatry, Nijmegen, The Netherlands) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Faraone, Stephen V. (SUNY Upstate Medical University. Departments of Psychiatry, of Neuroscience, and Physiology) ;
Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ;
Johansson, Stefan E. (University of Bergen. Department of Clinical Science) ;
Kuntsi, Jonna (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Larsson, Henrik (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ;
Lesch, Klaus-Peter (Maastricht University. Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS)) ;
Reif, Andreas (University Hospital of Frankfurt (Alemanya)) ;
Rohde, Luis Augusto (Hospital de Clínicas de Porto Alegre (Brasil)) ;
Casas Brugué, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Børglum, Anders D. (Center for Genomics and Personalized Medicine, Aarhus, Denmark) ;
Franke, Barbara (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by age-inappropriate symptoms of inattention, impulsivity, and hyperactivity that persist into adulthood in the majority of the diagnosed children. [...]
2020 - 10.1038/s41386-020-0664-5
Neuropsychopharmacology, Vol. 45 (april 2020) , p. 1617-1626
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