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14 p, 1.0 MB |
Pharmacological treatments and medication-related problems in nursing homes in Catalonia : a multidisciplinary approach
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Anderssen-Nordahl, Emilie (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez-Arcilla Rosanas, Margarita (Hospital Universitari Vall d'Hebron) ;
Bosch Ferrer, Montserrat (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Sabaté Gallego, Mònica (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Fernández-Liz, Eladio (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
San-José, Antonio (Hospital Universitari Vall d'Hebron) ;
Barceló-Colomer, Maria Estrella (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Background: Aging correlates with increased frailty, multi-morbidity, and chronic diseases. Furthermore, treating the aged often entails polypharmacy to achieve optimal disease management, augmenting medication-related problems (MRPs). [...]
2024 -  10.3389/fphar.2024.1320490
Frontiers in Pharmacology, Vol. 15 (march 2024) ,
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12 p, 1.6 MB |
Differences in mortality in critically ill elderly patients during the second COVID-19 surge in Europe
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Jung, Christian (Heinrich-Heine-University Duesseldorf) ;
Fjølner, Jesper (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Bruno, Raphael Romano (Heinrich-Heine-University Duesseldorf) ;
Wernly, Bernhard (Paracelsus Medical University) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bollen Pinto, Bernardo (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Wolff, Georg (Heinrich-Heine-University Duesseldorf) ;
Kelm, Malte (Heinrich-Heine-University Duesseldorf) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sviri, Sigal (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hadassah University Medical Center) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Czuczwar, Miroslaw (Medical University of Lublin) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Zafeiridis, Tilemachos (General University Hospital of Larissa (Grècia)) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Centro Hospitalar Universitário de Lisboa Central) ;
Leaver, Susannah (St George's University Hospital NHS Foundation Trust) ;
Boumendil, Ariane (Hôpital Saint-Antoine) ;
De Lange, Dylan W. (University Utrecht) ;
Guidet, Bertrand (Hôpital Saint-Antoine) ;
Flaatten, Hans (University of Bergen) ;
Universitat Autònoma de Barcelona
The primary aim of this study was to assess the outcome of elderly intensive care unit (ICU) patients treated during the spring and autumn COVID-19 surges in Europe. This was a prospective European observational study (the COVIP study) in ICU patients aged 70 years and older admitted with COVID-19 disease from March to December 2020 to 159 ICUs in 14 European countries. [...]
2021 - 10.1186/s13054-021-03739-7
Critical Care, Vol. 25 (september 2021)
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10 p, 496.7 KB |
Isatuximab plus carfilzomib and dexamethasone versus carfilzomib and dexamethasone in elderly patients with relapsed multiple myeloma : IKEMA subgroup analysis
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Facon, Thierry (Lille University Hospital) ;
Moreau, Philippe (University of Nantes) ;
Martin, Thomas G. (University of California San Francisco) ;
Spicka, Ivan (Charles University and General Hospital, Prague, Czech Republic) ;
Oriol, Albert (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Koh, Youngil (Seoul National University Hospital, South Korea) ;
Lim, Andrew (Austin & Repatriation Medical Center, Heidelberg, Victoria, Australia) ;
Mikala, Gabor (South Pest Central Hospital, Budapest, Hungary) ;
Rosiñol, Laura (Hospital Clínic i Provincial de Barcelona) ;
Yağci, Münci (Gazi University, Ankara, Turkey) ;
Cavo, Michele (Bologna University School of Medicine, Italy) ;
Yong, Kwee (University College Hospital, London, UK) ;
Risse, Marie Laure (Sanofi R&D, Vitry-Sur-Seine, France) ;
Asset, Gaëlle (Sanofi R&D, Chilly-Mazarin, France) ;
Schwab, Sandrine (Sanofi R&D, Chilly-Mazarin, France) ;
Martinez, Gracia (Hospital das Clínicas de São Paulo, Brazil)
In this subgroup analysis of the randomized, Phase 3 IKEMA study (NCT03275285), we evaluated efficacy and safety of the anti-CD38 monoclonal antibody isatuximab (Isa) in combination with carfilzomib-dexamethasone (Isa-Kd) versus Kd in older (≥70 years of age, n = 86) and younger (<70 years, n = 216) patients with relapsed multiple myeloma (MM). [...]
2022 - 10.1002/hon.3038
Hematological Oncology, Vol. 40 Núm. 5 (december 2022) , p. 1020-1029
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10 p, 3.2 MB |
Association of chronic heart failure with mortality in old intensive care patients suffering from Covid-19
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Bruno, Raphael Romano (Heinrich Heine University Düsseldorf) ;
Wernly, Bernhard (Paracelsus Medical University Salzburg) ;
Wolff, Georg (Heinrich Heine University Düsseldorf) ;
Fjølner, Jesper (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bollen Pinto, Bernardo (Geneva University Hospitals) ;
Schefold, Joerg C. (University of Bern) ;
Kindgen-Milles, Detlef (Heinrich Heine University Düsseldorf) ;
Baldia, Philipp Heinrich (Heinrich Heine University Düsseldorf) ;
Kelm, Malte (Medical Faculty of the Heinrich-Heine University) ;
Beil, Michael (Hebrew University of Jerusalem) ;
Sviri, Sigal (Hebrew University of Jerusalem) ;
van Heerden, Peter Vernon (Hebrew University of Jerusalem) ;
Szczeklik, Wojciech (Jagiellonian University Medical College) ;
Topeli, Arzu (Hacettepe University Faculty of Medicine) ;
Elhadi, Muhammed (University of Tripoli) ;
Joannidis, Michael (Medical University Innsbruck) ;
Oeyen, Sandra (Universitair Ziekenhuis Gent) ;
Kondili, Eumorfia (University Hospital of Heraklion) ;
Marsh, Brian (Mater Misericordiae University Hospital(Dublín, Irlanda)) ;
Andersen, Finn H. (Norwegian University of Science and Technology) ;
Moreno, Rui (Nova Medical School) ;
Leaver, Susannah (St George's University Hospitals NHS Foundation Trust) ;
Boumendil, Ariane (Hôpital Saint-Antoine) ;
De Lange, Dylan W. (Utrecht University) ;
Guidet, Bertrand (Hôpital Saint-Antoine) ;
Flaatten, Hans (Haukeland University Hospital (Bergen, Noruega)) ;
Jung, Christian (Heinrich Heine University Düsseldorf) ;
Universitat Autònoma de Barcelona
Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID-19). This prospective international multicentre study investigates the role of pre-existing CHF on clinical outcomes of critically ill old (≥70 years) intensive care patients with COVID-19. [...]
2022 - 10.1002/ehf2.13854
ESC Heart Failure, Vol. 9 (march 2022) , p. 1756-1765
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5 p, 206.7 KB |
Characteristics of potentially inappropriate prescribing of drugs in elderly polypathological patients Características del uso inadecuado de medicamentos en pacientes pluripatológicos de edad avanzada
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Rivas-Cobas, Paula Carolina (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Ramírez-Duque, Nieves (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Gómez Hernández, Mercedes (Hospital San Juan de Dios del Aljarafe) ;
García, Juana (Hospital General Juan Ramón Jiménez) ;
Agustí Escasany, M. Antònia (Hospital Universitari Vall d'Hebron) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Formiga, Francesc (Hospital Universitari de Bellvitge) ;
López-Soto, Alfonso (Hospital Clínic i Provincial de Barcelona) ;
Torres Bonafonte, Olga H (Institut d'Investigació Biomèdica Sant Pau) ;
San-José, Antonio (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
To analyse potentially inappropriate prescribing (PIP) in elderly polypathological patients (PP). Multicentre observational, prospective study of 672 patients aged 75 years and older hospitalised in Internal Medicine between April 2011 and March 2012. [...]
2017 - 10.1016/j.gaceta.2016.06.013
Gaceta sanitaria, Vol. 31 Núm. 4 (julio 2017) , p. 327-331
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9 p, 707.5 KB |
Compliance and Outcome of Elderly Patients Treated in the Concurrent Once-Daily Versus Twice-Daily Radiotherapy (CONVERT) Trial
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Christodoulou, M. (The Christie NHS Foundation Trust) ;
Blackhall, Fiona (University of Manchester) ;
Mistry, H. (University of Manchester) ;
Leylek, A. (CancerCare Manitoba) ;
Knegjens, J. (The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital) ;
Remouchamps, V. (CHU UCL Namur. site Ste Elisabeth) ;
Martel-Lafay, I. (Centre Léon Bérard) ;
Farré, Núria (Institut d'Investigació Biomèdica Sant Pau) ;
Zwitter, M. (Institute of Oncology) ;
Lerouge, D. (Centre François Baclesse (Caen, França)) ;
Pourel, N. (Institut Sainte-Catherine) ;
Janicot, H. (CHU Gabriel Montpied) ;
Scherpereel, A. (Hospital of the University (CHRU) of Lille) ;
Tissing-Tan, C. (Radiotherapiegroep) ;
Peignaux, K. (Georges Francois LECLERC Center) ;
Geets, X. (Cliniques universitaires Saint-Luc. MIRO-IREC-UCL) ;
Konopa, K. (Medical University of Gdansk) ;
Faivre-Finn, C. (University of Manchester)
There is a lack of data on the efficacy and safety of concurrent chemoradiotherapy in elderly, limited-stage, patients with SCLC. We compared outcomes of patients 70 years of age or older versus younger patients within the Concurrent Once-daily Versus twice-daily RadioTherapy (CONVERT) trial. [...]
2019 - 10.1016/j.jtho.2018.09.027
Journal of Thoracic Oncology, Vol. 14 Núm. 1 (january 2019) , p. 63-71
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9 p, 694.0 KB |
Influence of age on the occurrence of adverse events in rheumatic patients at the onset of biological treatment : Data from the BIOBADASER III register
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Vela, Paloma (ISABIAL) ;
Sanchez-Piedra, Carlos (Unidad de Investigación ser) ;
Pérez-García, Carolina (Hospital del Mar (Barcelona, Catalunya)) ;
Castro-Villegas, María C. (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ;
Freire, Mercedes (Hospital A Coruña) ;
Mateo, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Díaz Torne, César (Institut d'Investigació Biomèdica Sant Pau) ;
Bohórquez, Cristina (Hospital Príncipe de Asturias) ;
Blanco-Madrigal, Juan M. (Hospital de Basurto (Bilbao, Biscaia)) ;
Ros-Vilamajo, Inmaculada (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Gómez, Silvia (ISABIAL) ;
Caño, Rocio (ISABIAL) ;
Sánchez-Alonso, Fernando (Unidad de Investigación ser) ;
Díaz-González, Federico (Hospital Universitario de Canarias (La Laguna)) ;
Gómez-Reino, Juan J. (Hospital de Santiago) ;
Universitat Autònoma de Barcelona
To assess whether age, at the beginning of biologic treatment, is associated with the time a first adverse event (AE) appears in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS), or psoriatic arthritis (PsA). [...]
2020 - 10.1186/s13075-020-02231-x
Arthritis research & therapy, Vol. 22 Núm. 1 (15 2020) , p. 143
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23 p, 188.3 KB |
Edadismo y discursos de las personas mayores sobre la vejez y el envejecer en Chile
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Pavez Lizarraga, Amaya (Universidad de Santiago de Chile) ;
Baeza Correa, Cecilia (Universidad de Santiago de Chile) ;
Faure Bascur, Eyleen (Universidad de Santiago de Chile) ;
Pallavicini Magnere, Patricia (Universidad de Santiago de Chile)
Los resultados que presentamos dan cuenta de los significados asociados a discursos de personas mayores chilenas, acerca de la vejez y del envejecer. Como marco referencial, nos nutrimos de la gerontología crítica y aproximaciones feministas e interseccionales acerca de las condiciones del envejecimiento en Latinoamérica. [...]
The results that we present, account for the meanings associated with discourses of Chilean older people, about old age and aging. As a frame of reference, we draw on critical gerontology and feminist and intersectional approaches to the conditions of aging in Latin America. [...]
2023 - 10.5565/rev/athenea.3386
Athenea digital : revista de pensamiento e investigación social, Vol. 23 Núm. 3 (2023) , p. e3386 (Artículos)
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7 p, 442.8 KB |
Treatment decision-making in chronic lymphocytic leukaemia : Key factors for healthcare professionals. PRELIC study
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Boque, Concepcion (Institut Català d'Oncologia) ;
Abad, María Reyes (Hospital Universitario Miguel Servet (Saragossa)) ;
Agustin Ferrandez, Maria Jose (Hospital Universitario Miguel Servet (Saragossa)) ;
García-Goñi, Manuel (Universidad Complutense de Madrid) ;
Moreno, Carolina M. (Institut d'Investigació Biomèdica Sant Pau) ;
Gabás-Rivera, Clara (Outcomes 10) ;
Granados, Enrique (Gilead Sciences) ;
Castro-Gómez, Antonio (Gilead Sciences) ;
Pardo, Carlos (Gilead Sciences) ;
Lizán, Luis (Universitat Jaume I)
To explore the preferences of Spanish healthcare professionals (haematologists and hospital pharmacists) for the treatment selection of active Chronic Lymphocytic Leukaemia (CLL) patients at first relapse, condition that mainly afflicts older adults. [...]
2020 - 10.1016/j.jgo.2019.03.010
Journal of Geriatric Oncology, Vol. 11 Núm. 1 (january 2020) , p. 24-30
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