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Articles 2 records found  
18 p, 3.4 MB Learning improvement after PI3K activation correlates with de novo formation of functional small spines / Enriquez-Barreto, Lilian (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Cuesto, Germán (Centro de Investigación Biomédica (La Rioja)) ; Dominguez-Iturza, Nuria (Centro de Investigación Biomédica (La Rioja)) ; Gavilán, Elena (Universidad de Sevilla. Instituto de Biomedicina de Sevilla) ; Ruano, Diego (Universidad de Sevilla. Instituto de Biomedicina de Sevilla) ; Sandi, Carmen (École Polytechnique Fédérale de Lausanne. Brain Mind Institute) ; Fernández-Ruiz, Antonio (Instituto Cajal-CSIC) ; Martín-Vázquez, Gonzalo (Instituto Cajal-CSIC) ; Herreras, Oscar (Instituto Cajal-CSIC) ; Morales, Miguel (Centro de Investigación Biomédica (La Rioja)) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
PI3K activation promotes the formation of synaptic contacts and dendritic spines, morphological features of glutamatergic synapses that are commonly known to be related to learning processes. In this report, we show that in vivo administration of a peptide that activates the PI3K signaling pathway increases spine density in the rat hippocampus and enhances the animals' cognitive abilities, while in vivo electrophysiological recordings show that PI3K activation results in synaptic enhancement of Schaffer and stratum lacunosum moleculare inputs. [...]
2014 - 10.3389/fnmol.2013.00054
Frontiers in molecular neuroscience, Vol. 6 (January 2014) , art. 54  
12 p, 167.1 KB Infografía y Patrimonio Arquitectónico / Fernández Ruiz, José Antonio (Escuela Técnica Superior de Arquitectura (Granada, Andalusia))
Ofereix un panorama teòric deles representacions virtuals en arquitectura i consciencia sobre la trascendència del canvi tecnològic. Reflexiona sobre les cauteles necessàries davant d'aquestes representacions tot reclamant un àmbit científic propi. [...]
Ofrece un panorama teórico de las representaciones virtuales en arquitectura. Conciencia sobre la trascendencia del cambio tecnológico. Reflexiona sobre las cautelas necesarias ante estas representaciones reclamando un ámbito científico propio. [...]
This paper offers a theoretical overview about virtual representations in architecture and points to the transcendence of technological change, reflects on the necessary caution to be taken in relation to these kind of representations and defends an own scientific area. [...]

Treballs d'arqueologia, N. 12 (2006) p. 23-34  

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